Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes von Lee, Michael, Hills, Mark, Conomos, Dimitri, Stutz, Michael D, Dagg, Rebecca A, Lau, Loretta M S, Reddel, Roger R, Pickett, Hilda A

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Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres von Dagg, Rebecca A., Pickett, Hilda A., Neumann, Axel A., Napier, Christine E., Henson, Jeremy D., Teber, Erdahl T., Arthur, Jonathan W., Reynolds, C. Patrick, Murray, Jayne, Haber, Michelle, Sobinoff, Alexander P., Lau, Loretta M.S., Reddel, Roger R.

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Whole-genome landscapes of major melanoma subtypes von Hayward, Nicholas K., Wilmott, James S., Waddell, Nicola, Johansson, Peter A., Field, Matthew A., Nones, Katia, Patch, Ann-Marie, Kakavand, Hojabr, Alexandrov, Ludmil B., Burke, Hazel, Jakrot, Valerie, Kazakoff, Stephen, Holmes, Oliver, Leonard, Conrad, Sabarinathan, Radhakrishnan, Mularoni, Loris, Wood, Scott, Xu, Qinying, Waddell, Nick, Tembe, Varsha, Pupo, Gulietta M., De Paoli-Iseppi, Ricardo, Vilain, Ricardo E., Shang, Ping, Lau, Loretta M. S., Dagg, Rebecca A., Schramm, Sarah-Jane, Pritchard, Antonia, Dutton-Regester, Ken, Newell, Felicity, Fitzgerald, Anna, Shang, Catherine A., Grimmond, Sean M., Pickett, Hilda A., Yang, Jean Y., Stretch, Jonathan R., Behren, Andreas, Kefford, Richard F., Hersey, Peter, Long, Georgina V., Cebon, Jonathan, Shackleton, Mark, Spillane, Andrew J., Saw, Robyn P. M., López-Bigas, Núria, Pearson, John V., Thompson, John F., Scolyer, Richard A., Mann, Graham J.

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Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma von Ziegler, David S., Wong, Marie, Mayoh, Chelsea, Kumar, Amit, Tsoli, Maria, Mould, Emily, Tyrrell, Vanessa, Khuong-Quang, Dong-Anh, Pinese, Mark, Gayevskiy, Velimir, Cohn, Richard J., Lau, Loretta M. S., Reynolds, Mark, Cox, Michael C., Gifford, Andrew, Rodriguez, Michael, Cowley, Mark J., Ekert, Paul G., Marshall, Glenn M., Haber, Michelle

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Parents' and adolescents' perspectives and understanding of information about childhood cancer precision medicine von Gereis, Jessica M, Hetherington, Kate, Robertson, Eden G, Daly, Rebecca, Donoghoe, Mark W, Ziegler, David S, Marshall, Glenn M, Lau, Loretta M S, Marron, Jonathan M, Wakefield, Claire E

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High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer von Mayoh, Chelsea, Mao, Jie, Xie, Jinhan, Tax, Gabor, Chow, Shu-Oi, Cadiz, Roxanne, Pazaky, Karina, Barahona, Paulette, Ajuyah, Pamela, Trebilcock, Peter, Malquori, Angela, Gunther, Kate, Avila, Anica, Yun, Doo Young, Alfred, Stephanie, Gopalakrishnan, Anjana, Kamili, Alvin, Wong, Marie, Cowley, Mark J, Jessop, Sophie, Lau, Loretta M S, Trahair, Toby N, Ziegler, David S, Fletcher, Jamie I, Gifford, Andrew J, Tsoli, Maria, Marshall, Glenn M, Haber, Michelle, Tyrrell, Vanessa, Failes, Timothy W, Arndt, Greg M, Lock, Richard B, Ekert, Paul G, Dolman, M Emmy M

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Telomere sequence content can be used to determine ALT activity in tumours von Lee, Michael, Teber, Erdahl T, Holmes, Oliver, Nones, Katia, Patch, Ann-Marie, Dagg, Rebecca A, Lau, Loretta M S, Lee, Joyce H, Napier, Christine E, Arthur, Jonathan W, Grimmond, Sean M, Hayward, Nicholas K, Johansson, Peter A, Mann, Graham J, Scolyer, Richard A, Wilmott, James S, Reddel, Roger R, Pearson, John V, Waddell, Nicola, Pickett, Hilda A

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Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes von Ajuyah, Pamela, Mayoh, Chelsea, Lau, Loretta M. S., Barahona, Paulette, Wong, Marie, Chambers, Hazel, Valdes-Mora, Fatima, Senapati, Akanksha, Gifford, Andrew J., D’Arcy, Colleen, Hansford, Jordan R., Manoharan, Neevika, Nicholls, Wayne, Williams, Molly M., Wood, Paul J., Cowley, Mark J., Tyrrell, Vanessa, Haber, Michelle, Ekert, Paul G., Ziegler, David S., Khuong-Quang, Dong-Anh

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Loss of wild-type ATRX expression in somatic cell hybrids segregates with activation of Alternative Lengthening of Telomeres von Bower, Kylie, Napier, Christine E, Cole, Sara L, Dagg, Rebecca A, Lau, Loretta M S, Duncan, Emma L, Moy, Elsa L, Reddel, Roger R

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Detection of alternative lengthening of telomeres by telomere quantitative PCR von Lau, Loretta M S, Dagg, Rebecca A, Henson, Jeremy D, Au, Amy Y M, Royds, Janice A, Reddel, Roger R

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Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis von Manoharan, Neevika, Ajuyah, Pamela, Senapati, Akanksha, Wong, Marie, Mullins, Anna, Rodriguez, Michael, Doyle, Helen, McCowage, Geoff, Lau, Loretta M. S., Ekert, Paul G., Ziegler, David S.

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The C-Circle Biomarker Is Secreted by Alternative-Lengthening-of-Telomeres Positive Cancer Cells inside Exosomes and Provides a Blood-Based Diagnostic for ALT Activity von Chen, Yuan-Yin, Dagg, Rebecca, Zhang, Yuchen, Lee, Joyce H. Y., Lu, Robert, Martin La Rotta, Nancy, Sampl, Sandra, Korkut-Demirbas, Medina, Holzmann, Klaus, Lau, Loretta M. S., Reddel, Roger R., Henson, Jeremy D.

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Pediatric spindle cell/sclerosing rhabdomyosarcoma with FUS-TFCP2 fusion: a case report and literature review von Fang, Zishi, Duan, Chao, Wang, Shengcai, Fu, Libing, Yang, Peiyi, Yu, Tong, Deel, Michael D, Lau, Loretta M S, Ma, Xiaoli, Ni, Xin, Su, Yan

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Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations von Farooqi, Ahsan S., Dagg, Rebecca A., Choi, L. Mi Rim, Shay, Jerry W., Reynolds, C. Patrick, Lau, Loretta M. S.

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Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnos... von Fuentes Bolanos, Noemi Auxiliadora, Padhye, Bhavna, Daley, Macabe, Hunter, Jacqueline, Hetherington, Kate, Warby, Meera, Courtney, Eliza, Kirk, Judy, Josephi-Taylor, Sarah, Chen, Yuyan, Alvaro, Frank, Barlow-Stewart, Kristine, Wong-Erasmus, Marie, Barahona, Paulette, Ajuyah, Pamela, Altekoester, Ann-Kristin, Tyrrell, Vanessa J, Lau, Loretta M S, Wakefield, Claire, Sylvester, Dianne, Tucker, Katherine, Pinese, Mark, Dalla Pozza, Luciano, O’Brien, Tracey A

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Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial von Daly, Rebecca, Hetherington, Kate, Hazell, Emily, Wadling, Bethany R, Tyrrell, Vanessa, Tucker, Katherine M, Marshall, Glenn M, Ziegler, David S, Lau, Loretta M S, Trahair, Toby N, O'Brien, Tracey A, Collins, Kiri, Gifford, Andrew J, Haber, Michelle, Pinese, Mark, Malkin, David, Cowley, Mark J, Karpelowsky, Jonathan, Drew, Donna, Jacobs, Chris, Wakefield, Claire E

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Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor von Nagabushan, Sumanth, Lau, Loretta M. S., Barahona, Paulette, Wong, Marie, Sherstyuk, Alexandra, Marshall, Glenn M., Tyrrell, Vanessa, Wegner, Eva A., Ekert, Paul G., Cowley, Mark J., Mayoh, Chelsea, Trahair, Toby N., Crowe, Philip, Anazodo, Antoinette, Ziegler, David S.

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Advances in paediatric cancer treatment von Saletta, Federica, Seng, Michaela S, Lau, Loretta M S

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Translating palbociclib to the clinic for DIPG - What is truly achievable? von Franshaw, Laura, Tsoli, Maria, Lau, Loretta M.S., Ziegler, David S.

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qmotif: determination of telomere content from whole-genome sequence data von Holmes, Oliver, Nones, Katia, Tang, Yue Hang, Loffler, Kelly A, Lee, Michael, Patch, Ann-Marie, Dagg, Rebecca A, Lau, Loretta M S, Leonard, Conrad, Wood, Scott, Xu, Qinying, Pickett, Hilda A, Reddel, Roger R, Barbour, Andrew P, Grimmond, Sean M, Waddell, Nicola, Pearson, John V

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