Clinical importance of risk variants in the dihydropyrimidine dehydrogenase gene for the prediction of early‐onset fluoropyrimidine toxicity von Froehlich, Tanja K., Amstutz, Ursula, Aebi, Stefan, Joerger, Markus, Largiadèr, Carlo R.

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Association of the Intestinal Microbiome with the Development of Neovascular Age-Related Macular Degeneration von Zinkernagel, Martin S., Zysset-Burri, Denise C., Keller, Irene, Berger, Lieselotte E., Leichtle, Alexander B., Largiadèr, Carlo R., Fiedler, Georg M., Wolf, Sebastian

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Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of... von Meulendijks, Didier, PharmD, Henricks, Linda M, PharmD, Sonke, Gabe S, MD, Deenen, Maarten J, PhD, Froehlich, Tanja K, PhD, Amstutz, Ursula, PhD, Largiadèr, Carlo R, Prof, Jennings, Barbara A, PhD, Marinaki, Anthony M, PhD, Sanderson, Jeremy D, MD, Kleibl, Zdenek, PhD, Kleiblova, Petra, PhD, Schwab, Matthias, Prof, Zanger, Ulrich M, Prof, Palles, Claire, PhD, Tomlinson, Ian, Prof, Gross, Eva, PhD, van Kuilenburg, André B P, PhD, Punt, Cornelis J A, Prof, Koopman, Miriam, MD, Beijnen, Jos H, Prof, Cats, Annemieke, MD, Schellens, Jan H M, Prof

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Annual incidence and severity of acute episodes in hereditary thrombotic thrombocytopenic purpura von Tarasco, Erika, Bütikofer, Lukas, Friedman, Kenneth D., George, James N., Hrachovinova, Ingrid, Knöbl, Paul N., Matsumoto, Masanori, von Krogh, Anne Sophie, Aebi-Huber, Isabella, Cermakova, Zuzana, Górska-Kosicka, Magdalena, Jalowiec, Katarzyna A., Largiadèr, Carlo R., Prohászka, Zoltán, Sinkovits, György, Windyga, Jerzy, Lämmle, Bernhard, Kremer Hovinga, Johanna A.

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Determinants of Interpatient Variability in Treosulfan Pharmacokinetics in AML Patients Undergoing Autologous Stem Cell Transplantation von Ayçiçek, Selin G, Akhoundova, Dilara, Bacher, Ulrike, Hayoz, Michael, Aebi, Yolanda, Largiadèr, Carlo R, Pabst, Thomas

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Approach for Phased Sequence-Based Genotyping of the Critical Pharmacogene Dihydropyrimidine Dehydrogenase ( DPYD ) von Ambrodji, Alisa, Sadlon, Angélique, Amstutz, Ursula, Hoch, Dennis, Berger, Martin D, Bastian, Sara, Offer, Steven M, Largiadèr, Carlo R

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The gut microbiome and HLA-B27-associated anterior uveitis: a case-control study von Morandi, Sophia C, Herzog, Elio L, Munk, Marion, Kreuzer, Marco, Largiadèr, Carlo R, Wolf, Sebastian, Zinkernagel, Martin, Zysset-Burri, Denise C

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The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017 von van Dorland, Hendrika A, Taleghani, Magnus Mansouri, Sakai, Kazuya, Friedman, Kenneth D, George, James N, Hrachovinova, Ingrid, Knöbl, Paul N, von Krogh, Anne Sophie, Schneppenheim, Reinhard, Aebi-Huber, Isabella, Bütikofer, Lukas, Largiadèr, Carlo R, Cermakova, Zuzana, Kokame, Koichi, Miyata, Toshiyuki, Yagi, Hideo, Terrell, Deirdra R, Vesely, Sara K, Matsumoto, Masanori, Lämmle, Bernhard, Fujimura, Yoshihiro, Kremer Hovinga, Johanna A

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Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5‐fluorour... von Hamzic, Seid, Schärer, Dominic, Offer, Steven M., Meulendijks, Didier, Nakas, Christos, Diasio, Robert B., Fontana, Stefano, Wehrli, Marc, Schürch, Stefan, Amstutz, Ursula, Largiadèr, Carlo R.

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LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity p... von Büchel, Barbara, Rhyn, Peter, Schürch, Stefan, Bühr, Claudia, Amstutz, Ursula, R. Largiadèr, Carlo

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Dihydropyrimidine Dehydrogenase Testing prior to Treatment with 5-Fluorouracil, Capecitabine, and Tegafur: A Consensus Paper von Wörmann, Bernhard, Bokemeyer, Carsten, Burmeister, Thomas, Köhne, Claus-Henning, Schwab, Matthias, Arnold, Dirk, Blohmer, Jens-Uwe, Borner, Markus, Brucker, Sara, Cascorbi, Ingolf, Decker, Thomas, de Wit, Maike, Dietz, Andreas, Einsele, Hermann, Eisterer, Wolfgang, Folprecht, Gunnar, Hilbe, Wolfgang, Hoffmann, Jürgen, Knauf, Wolfgang, Kunzmann, Volker, Largiadèr, Carlo R., Lorenzen, Sylvie, Lüftner, Diana, Moehler, Markus, Nöthen, Markus M., Pox, Christian, Reinacher-Schick, Anke, Scharl, Anton, Schlegelberger, Brigitte, Seufferlein, Thomas, Sinn, Marianne, Stroth, Matthias, Tamm, Ingo, Trümper, Lorenz, Wilhelm, Martin, Wöll, Ewald, Hofheinz, Ralf-Dieter

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Genotype-guided fluoropyrimidine dosing: ready for implementation von Amstutz, Ursula, Largiadèr, Carlo R

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Comparison of methods for donor-derived cell-free DNA quantification in plasma and urine from solid organ transplant recipients von Kueng, Nicholas, Arcioni, Séverine, Sandberg, Fanny, Kuhn, Christian, Banz, Vanessa, Largiadèr, Carlo R, Sidler, Daniel, Amstutz, Ursula

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Recent habitat fragmentation caused by major roads leads to reduction of gene flow and loss of genetic variability in ground beetles von Keller, Irene, Largiadèr, Carlo R.

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Increased erythroferrone levels in malarial anaemia von Neyer, Peter J., Kaboré, Bérenger, Nakas, Christos T., Diallo, Salou, Tinto, Halidou, Post, Annelies, Ven, Andre J., Huber, Andreas R., Largiadèr, Carlo R., Hammerer‐Lercher, Angelika

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Clinical Implementation of DPYD Pharmacogenetic Testing to Prevent Early-Onset Fluoropyrimidine-Related Toxicity in Cancer Patients in Switzerland von Begré, Ursina B M, Jörger, Markus, Aebi, Stefan, Amstutz, Ursula, Largiadèr, Carlo R

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Serological testing for SARS‐CoV‐2 antibodies in clinical practice: A comparative diagnostic accuracy study von Horn, Michael P., Jonsdottir, Hulda R., Brigger, Daniel, Damonti, Lauro, Suter‐Riniker, Franziska, Endrich, Olga, Froehlich, Tanja K., Fiedler, Martin, Largiadèr, Carlo R., Marschall, Jonas, Weber, Benjamin, Eggel, Alexander, Nagler, Michael

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Accuracy of serological testing for SARS‐CoV‐2 antibodies: First results of a large mixed‐method evaluation study von Brigger, Daniel, Horn, Michael P., Pennington, Luke F., Powell, Abigail E., Siegrist, Denise, Weber, Benjamin, Engler, Olivier, Piezzi, Vanja, Damonti, Lauro, Iseli, Patricia, Hauser, Christoph, Froehlich, Tanja K., Villiger, Peter M., Bachmann, Martin F., Leib, Stephen L., Bittel, Pascal, Fiedler, Martin, Largiadèr, Carlo R., Marschall, Jonas, Stalder, Hanspeter, Kim, Peter S., Jardetzky, Theodore S., Eggel, Alexander, Nagler, Michael

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Rs895819 in MIR27A improves the predictive value of DPYD variants to identify patients at risk of severe fluoropyrimidine‐associated toxicity von Meulendijks, Didier, Henricks, Linda M., Amstutz, Ursula, Froehlich, Tanja K., Largiadèr, Carlo R., Beijnen, Jos H., de Boer, Anthonius, Deenen, Maarten J., Cats, Annemieke, Schellens, Jan H.M.

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Come a long way, still a ways to go: from predicting and preventing fluoropyrimidine toxicity to increased efficacy? von Hamzic, Seid, Amstutz, Ursula, Largiadèr, Carlo R

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