The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway von Bailly, A, Perrin, A, Bou Malhab, L J, Pion, E, Larance, M, Nagala, M, Smith, P, O'Donohue, M-F, Gleizes, P-E, Zomerdijk, J, Lamond, A I, Xirodimas, D P

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Acute or Chronic Upregulation of Mitochondrial Fatty Acid Oxidation Has No Net Effect on Whole-Body Energy Expenditure or Adiposity von Hoehn, Kyle L., Turner, Nigel, Swarbrick, Michael M., Wilks, Donna, Preston, Elaine, Phua, Yuwei, Joshi, Himani, Furler, Stuart M., Larance, Mark, Hegarty, Bronwyn D., Leslie, Simon J., Pickford, Russell, Hoy, Andrew J., Kraegen, Edward W., James, David E., Cooney, Gregory J.

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PB0861 Endoplasmic Reticulum (ER) Stress is Increased in Diabetic Platelets and Contributes to Platelet Hyperactivity von Kong, Y., Rehan, R., Ghani, F., Fenwick, J., Robertshaw, D., Trang, V., Madsen, S., Potter, M., Cooke, K., Stoeckli, J., Morahan, G., Cartland, S., Kavurma, M., Cielesh, M., Zhang, Y., Yang, J., James, D., Weaver, J., Larance, M., Passam, F.

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Cab45G trafficking through the insulin secretory pathway is altered in human type 2 diabetes von Germanos, M., Yau, B., Taper, M., Yeoman, C., Wilson, A., An, Y., Cattin-Ortolá, J., Maslar, D., Tong, J., Naghiloo, S., Needham, E.J., van der Kraan, A.G., Sun, K., Loudovaris, T., Diaz-Vegas, A., Larance, M., Thomas, H., von Blume, J., Thorn, P., Ailion, M., Asensio, C.S., Kebede, M.A.

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The "Mutated in Colorectal Cancer" Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint von Pangon, Laurent, Sigglekow, Nicholas D, Larance, Mark, Al-Sohaily, Sam, Mladenova, Dessislava N, Selinger, Christina I, Musgrove, Elizabeth A, Kohonen-Corish, Maija R J

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Two-dimensional liquid chromatography/tandem mass spectrometry analysis of Gradiflow™ fractionated native human plasma von Wasinger, Valerie C., Locke, Vicki L., Raftery, Mark J., Larance, Mark, Rothemund, Deborah, Liew, Audrey, Bate, Irene, Guilhaus, Michael

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The docking protein and proto-oncogene product Gab2 is regulated via a novel negative feedback mechanism mediated by 14-3-3 binding von Brummer, T, Larance, M, Abreu, MT Herrera, Lyons, RJ, Timpson, P, Emmerich, CH, Fleuren, EDG, Lehrbach, GM, Schramek, D, Guilhaus, M, James, DE, Daly, RJ

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Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan von Richman, T.R, Ermer, J.A, Siira, S.J, Kuznetsova, I, Brosnan, C.A, Rossetti, G, Baker, J, Perks, K.L, Cserne Szappanos, H, Viola, H.M, Gray, N, Larance, M, Hool, L.C, Zuryn, S, Rackham, Oliver, Filipovska, A

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Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress von Byrne, FL, Olzomer, EM, Marriott, GR, Quek, LE, Katen, A, Su, J, Nelson, ME, Hart-Smith, G, Larance, M, Sebesfi, VF, Cuff, J, Martyn, GE, Childress, E, Alexopoulos, SJ, Poon, IK, Faux, MC, Burgess, AW, Reid, G, McCarroll, JA, Santos, WL, Quinlan, KG, Turner, N, Fazakerley, DJ, Kumar, N, Hoehn, KL

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The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription von Akay, A, Di Domenico, T, Suen, KM, Nabih, A, Parada, GE, Larance, M, Medhi, R, Berkyurek, Zhang, X, Wedeles, CJ, Rudolph, Engelhardt, J, Hemberg, M, Ma, P, Lamond, AI, Claycomb, JM, Miska

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The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription von Akay, A, Di Domenico, T, Suen, KM, Nabih, A, Parada, GE, Larance, M, Medhi, R, Berkyurek, AC, Zhang, X, Wedeles, CJ, Rudolph, KLM, Engelhardt, J, Hemberg, M, Ma, P, Lamond, AI, Claycomb, JM, Miska, EA

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Production of Large Amounts of Pure Water von Marvin, Kenneth T, Lansford, Larance M

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Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study von Campbell, Gabrielle, Hall, Wayne D, Peacock, Amy, Lintzeris, Nicholas, Bruno, Raimondo, Larance, Briony, Nielsen, Suzanne, Cohen, Milton, Chan, Gary, Mattick, Richard P, Blyth, Fiona, Shanahan, Marian, Dobbins, Timothy, Farrell, Michael, Degenhardt, Louisa

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Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus von Sangesland, Maya, Ronsard, Larance, Kazer, Samuel W., Bals, Julia, Boyoglu-Barnum, Seyhan, Yousif, Ashraf S., Barnes, Ralston, Feldman, Jared, Quirindongo-Crespo, Maricel, McTamney, Patrick M., Rohrer, Daniel, Lonberg, Nils, Chackerian, Bryce, Graham, Barney S., Kanekiyo, Masaru, Shalek, Alex K., Lingwood, Daniel

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The Pain and Opioids IN Treatment study: characteristics of a cohort using opioids to manage chronic non-cancer pain von Campbell, Gabrielle, Nielsen, Suzanne, Bruno, Raimondo, Lintzeris, Nicholas, Cohen, Milton, Hall, Wayne, Larance, Briony, Mattick, Richard P., Degenhardt, Louisa

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Polyphenols Mediate Neuroprotection in Cerebral Ischemic Stroke-An Update von Abdelsalam, Salaheldin Abdelraouf, Renu, Kaviyarasi, Zahra, Hamad Abu, Abdallah, Basem M, Ali, Enas M, Veeraraghavan, Vishnu Priya, Sivalingam, Kalaiselvi, Ronsard, Larance, Ammar, Rebai Ben, Vidya, Devanathadesikan Seshadri, Karuppaiya, Palaniyandi, Al-Ramadan, S Y, Rajendran, Peramaiyan

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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds von Wamhoff, Eike-Christian, Ronsard, Larance, Feldman, Jared, Knappe, Grant A., Hauser, Blake M., Romanov, Anna, Case, James Brett, Sanapala, Shilpa, Lam, Evan C., Denis, Kerri J. St, Boucau, Julie, Barczak, Amy K., Balazs, Alejandro B., Diamond, Michael S., Schmidt, Aaron G., Lingwood, Daniel, Bathe, Mark

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Chromatin Modifiers SET-25 and SET-32 Are Required for Establishment but Not Long-Term Maintenance of Transgenerational Epigenetic Inheritance von Woodhouse, Rachel M., Buchmann, Gabriele, Hoe, Matthew, Harney, Dylan J., Low, Jason K.K., Larance, Mark, Boag, Peter R., Ashe, Alyson

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Engaging an HIV vaccine target through the acquisition of low B cell affinity von Ronsard, Larance, Yousif, Ashraf S., Nait Mohamed, Faez Amokrane, Feldman, Jared, Okonkwo, Vintus, McCarthy, Caitlin, Schnabel, Julia, Caradonna, Timothy, Barnes, Ralston M., Rohrer, Daniel, Lonberg, Nils, Schmidt, Aaron, Lingwood, Daniel

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