Regulation and aggregation of intrinsically disordered peptides von Levine, Zachary A., Larini, Luca, LaPointe, Nichole E., Feinstein, Stuart C., Shea, Joan-Emma

Volltext

Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: Implications for chemotherapy-induced peripheral neu... von LaPointe, Nichole E., Morfini, Gerardo, Brady, Scott T., Feinstein, Stuart C., Wilson, Leslie, Jordan, Mary Ann

Volltext

Tau Assembly: The Dominant Role of PHF6 (VQIVYK) in Microtubule Binding Region Repeat R3 von Ganguly, Pritam, Do, Thanh D, Larini, Luca, LaPointe, Nichole E, Sercel, Alexander J, Shade, Madeleine F, Feinstein, Stuart C, Bowers, Michael T, Shea, Joan-Emma

Volltext

The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity von LaPointe, Nichole E., Morfini, Gerardo, Pigino, Gustavo, Gaisina, Irina N., Kozikowski, Alan P., Binder, Lester I., Brady, Scott T.

Volltext

Amino Acid Metaclusters: Implications of Growth Trends on Peptide Self-Assembly and Structure von Do, Thanh D, de Almeida, Natália E. C, LaPointe, Nichole E, Chamas, Ali, Feinstein, Stuart C, Bowers, Michael T

Volltext

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport von Kanaan, Nicholas M, Morfini, Gerardo, Pigino, Gustavo, LaPointe, Nichole E, Andreadis, Athena, Song, Yuyu, Leitman, Ellen, Binder, Lester I, Brady, Scott T

Volltext

A novel MAPT mutation, G55R, in a frontotemporal dementia patient leads to altered Tau function von Iyer, Abhinaya, Lapointe, Nichole E, Zielke, Krzysztof, Berdynski, Mariusz, Guzman, Elmer, Barczak, Anna, Chodakowska-Żebrowska, Małgorzata, Barcikowska, Maria, Feinstein, Stuart, Zekanowski, Cezary

Volltext

Oligomerization of the microtubule‐associated protein tau is mediated by its N‐terminal sequences: implications for normal and pathological tau action von Feinstein, H. Eric, Benbow, Sarah J., LaPointe, Nichole E., Patel, Nirav, Ramachandran, Srinivasan, Do, Thanh D., Gaylord, Michelle R., Huskey, Noelle E., Dressler, Nicolette, Korff, Megan, Quon, Brady, Cantrell, Kristi Lazar, Bowers, Michael T., Lal, Ratnesh, Feinstein, Stuart C.

Volltext

Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE... von Best, Rebecca L., LaPointe, Nichole E., Azarenko, Olga, Miller, Herb, Genualdi, Christine, Chih, Stephen, Shen, Ben-Quan, Jordan, Mary Ann, Wilson, Leslie, Feinstein, Stuart C., Stagg, Nicola J.

Volltext

Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases von Kanaan, Nicholas M, Morfini, Gerardo A, LaPointe, Nichole E, Pigino, Gustavo F, Patterson, Kristina R, Song, Yuyu, Andreadis, Athena, Fu, Yifan, Brady, Scott T, Binder, Lester I

Volltext

Amyloid β‑Protein C‑Terminal Fragments: Formation of Cylindrins and β‑Barrels von Do, Thanh D, LaPointe, Nichole E, Nelson, Rebecca, Krotee, Pascal, Hayden, Eric Y, Ulrich, Brittany, Quan, Sarah, Feinstein, Stuart C, Teplow, David B, Eisenberg, David, Shea, Joan-Emma, Bowers, Michael T

Volltext

Tau isoform–specific stabilization of intermediate states during microtubule assembly and disassembly von Best, Rebecca L., LaPointe, Nichole E., Liang, Jiahao, Ruan, Kevin, Shade, Madeleine F., Wilson, Leslie, Feinstein, Stuart C.

Volltext

βIII-tubulin enhances efficacy of cabazitaxel as compared with docetaxel von Smiyun, Gregoriy, Azarenko, Olga, Miller, Herbert, Rifkind, Alexander, LaPointe, Nichole E., Wilson, Leslie, Jordan, Mary Ann

Volltext

Tau Aggregation Propensity Engrained in Its Solution State von Eschmann, Neil A, Do, Thanh D, LaPointe, Nichole E, Shea, Joan-Emma, Feinstein, Stuart C, Bowers, Michael T, Han, Songi

Volltext

Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study von Larini, Luca, Gessel, Megan Murray, LaPointe, Nichole E, Do, Thanh D, Bowers, Michael T, Feinstein, Stuart C, Shea, Joan-Emma

Volltext

1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose binds to the N-terminal metal binding region to inhibit amyloid β-protein oligomer and fibril formation von de Almeida, Natália E.C., Do, Thanh D., LaPointe, Nichole E., Tro, Michael, Feinstein, Stuart C., Shea, Joan-Emma, Bowers, Michael T.

Volltext

Effects of pH and Charge State on Peptide Assembly: The YVIFL Model System von Do, Thanh D, LaPointe, Nichole E, Economou, Nicholas J, Buratto, Steven K, Feinstein, Stuart C, Shea, Joan-Emma, Bowers, Michael T

Volltext

Factors That Drive Peptide Assembly from Native to Amyloid Structures: Experimental and Theoretical Analysis of [Leu-5]-Enkephalin Mutants von Do, Thanh D, LaPointe, Nichole E, Sangwan, Smriti, Teplow, David B, Feinstein, Stuart C, Sawaya, Michael R, Eisenberg, David S, Bowers, Michael T

Volltext

Factors That Drive Peptide Assembly and Fibril Formation: Experimental and Theoretical Analysis of Sup35 NNQQNY Mutants von Do, Thanh D, Economou, Nicholas J, LaPointe, Nichole E, Kincannon, William M, Bleiholder, Christian, Feinstein, Stuart C, Teplow, David B, Buratto, Steven K, Bowers, Michael T

Volltext

Opposing Effects of Cucurbit[7]uril and 1,2,3,4,6-Penta‑O‑galloyl-β‑d‑glucopyranose on Amyloid β25–35 Assembly von de Almeida, Natália E. C, Do, Thanh D, Tro, Michael, LaPointe, Nichole E, Feinstein, Stuart C, Shea, Joan-Emma, Bowers, Michael T

Volltext