Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents – A Potential Therapy for Cancer von Muvarak, Nidal E., Chowdhury, Khadiza, Xia, Limin, Robert, Carine, Choi, Eun Yong, Cai, Yi, Bellani, Marina, Zou, Ying, Singh, Zeba N., Duong, Vu H., Rutherford, Tyler, Nagaria, Pratik, Bentzen, Søren M., Seidman, Michael M., Baer, Maria R., Lapidus, Rena G., Baylin, Stephen B., Rassool, Feyruz V.

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Gamma Delta T Cell Therapy for Cancer: It Is Good to be Local von Pauza, C David, Liou, Mei-Ling, Lahusen, Tyler, Xiao, Lingzhi, Lapidus, Rena G, Cairo, Cristiana, Li, Haishan

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Analysis of the Mechanisms of Action of Naphthoquinone-Based Anti-Acute Myeloid Leukemia Chemotherapeutics von Lee, Michelle H, Lapidus, Rena G, Ferraris, Dana, Emadi, Ashkan

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Extracellular vesicle PD-L1 dynamics predict durable response to immune-checkpoint inhibitors and survival in patients with non-small cell lung cancer von de Miguel-Perez, Diego, Russo, Alessandro, Arrieta, Oscar, Ak, Murat, Barron, Feliciano, Gunasekaran, Muthukumar, Mamindla, Priyadarshini, Lara-Mejia, Luis, Peterson, Christine B, Er, Mehmet E, Peddagangireddy, Vishal, Buemi, Francesco, Cooper, Brandon, Manca, Paolo, Lapidus, Rena G, Hsia, Ru-Ching, Cardona, Andres F, Naing, Aung, Kaushal, Sunjay, Hirsch, Fred R, Mack, Philip C, Serrano, Maria Jose, Adamo, Vincenzo, Colen, Rivka R, Rolfo, Christian

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Regulation of cisplatin-resistant head and neck squamous cell carcinoma by the SRC/ETS-1 signaling pathway von Yang, Zejia, Liao, Jipei, Carter-Cooper, Brandon A, Lapidus, Rena G, Cullen, Kevin J, Dan, Hancai

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Dual targeting of glutamine and serine metabolism in acute myeloid leukemia von Hameed, Kanwal M, Bollino, Dominique R, Shetty, Amol C, Carter-Cooper, Brandon, Lapidus, Rena G, Emadi, Ashkan

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SIRT3, a metabolic target linked to ataxia-telangiectasia mutated (ATM) gene deficiency in diffuse large B-cell lymphoma von Bhalla, Kavita, Jaber, Sausan, Reagan, Kayla, Hamburg, Arielle, Underwood, Karen F., Jhajharia, Aditya, Singh, Maninder, Bhandary, Binny, Bhat, Shambhu, Nanaji, Nahid M., Hisa, Ruching, McCracken, Carrie, Creasy, Heather Huot, Lapidus, Rena G., Kingsbury, Tami, Mayer, Dirk, Polster, Brian, Gartenhaus, Ronald B.

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Erwinia asparaginase (crisantaspase) increases plasma levels of serine and glycine von Bollino, Dominique, Claiborne, J Preston, Hameed, Kanwal, Ma, Xinrong, Tighe, Kayla M, Carter-Cooper, Brandon, Lapidus, Rena G, Strovel, Erin T, Emadi, Ashkan

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Clinical and laboratory studies of the novel cyclin-dependent kinase inhibitor dinaciclib (SCH 727965) in acute leukemias von Gojo, Ivana, Sadowska, Mariola, Walker, Alison, Feldman, Eric J., Iyer, Swaminathan Padmanabhan, Baer, Maria R., Sausville, Edward A., Lapidus, Rena G., Zhang, Da, Zhu, Yali, Jou, Ying-Ming, Poon, Jennifer, Small, Karen, Bannerji, Rajat

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Comparison of Neuropathy-Inducing Effects of Eribulin Mesylate, Paclitaxel, and Ixabepilone in Mice von WOZNIAK, Krystyna M, NOMOTO, Kenichi, SLUSHER, Barbara S, LAPIDUS, Rena G, YING WU, CAROZZI, Valentina, CAVALETTI, Guido, HAYAKAWA, Kazuhiro, HOSOKAWA, Satoru, TOWLE, Murray J, LITTLEFIELD, Bruce A

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Long-acting Erwinia chrysanthemi, Pegcrisantaspase, induces alternate amino acid biosynthetic pathways in a preclinical model of pancreatic ductal adenocarcinoma von Bollino, Dominique, Hameed, Kanwal, Bhat, Anusha, Zarrabi, Arveen, Casildo, Andrea, Ma, Xinrong, Tighe, Kayla M, Carter-Cooper, Brandon, Strovel, Erin T, Lapidus, Rena G, Emadi, Ashkan

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Head and neck cancer radiosensitization by the novel poly(ADP-ribose) polymerase inhibitor GPI-15427 von Khan, Khurram, Araki, Koji, Wang, Daiyou, Li, Guayan, Li, Xin, Zhang, Jie, Xu, Weizheng, Hoover, Randall K., Lauter, Susan, O'Malley Jr, Bert, Lapidus, Rena G., Li, Daqing

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In Vivo Screening of S100B Inhibitors for Melanoma Therapy von Zimmer, Danna B., Lapidus, Rena G., Weber, David J.

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A novel XBP1 variant is highly enriched in cancer tissues and is specifically required for cancer cell survival von Zhong, Yongwang, Yan, Wenjing, Ruan, Jingjing, Fang, Mike, Lapidus, Rena G., Du, Shaojun, Fang, Shengyun

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Breaking Mitochondrial Fasting for Cancer Treatment: Old Wine in New Bottles von Emadi, Ashkan, Lapidus, Rena G

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Phase I Clinical Trial of DNA Methyltransferase Inhibitor Decitabine and PARP Inhibitor Talazoparib Combination Therapy in Relapsed/Refractory Acute Myeloid Leukemia von Baer, Maria R, Kogan, Aksinija A, Bentzen, Søren M, Mi, Tian, Lapidus, Rena G, Duong, Vu H, Emadi, Ashkan, Niyongere, Sandrine, O'Connell, Casey L, Youngblood, Benjamin A, Baylin, Stephen B, Rassool, Feyruz V

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Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency von McLaughlin, Lena J., Stojanovic, Lora, Kogan, Aksinija A., Rutherford, Julia L., Choi, Eun Yong, Yen, Ray-Whay Chiu, Xia, Limin, Zou, Ying, Lapidus, Rena G., Baylin, Stephen B., Topper, Michael J., Rassool, Feyruz V.

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PP2A-activating Drugs Enhance FLT3 Inhibitor Efficacy through AKT Inhibition-Dependent GSK-3 beta-Mediated c-Myc and Pim-1 Proteasomal Degradation von Scarpa, Mario, Singh, Prerna, Bailey, Christopher M., Lee, Jonelle K., Kapoor, Shivani, Lapidus, Rena G., Niyongere, Sandrine, Sangodkar, Jaya, Wang, Yin, Perrotti, Danilo, Narla, Goutham, Baer, Maria R.

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Pulsed focused ultrasound lowers interstitial fluid pressure and increases nanoparticle delivery and penetration in head and neck squamous cell carcinoma xenograft tumors von Mohammadabadi, Ali, Huynh, Ruby N, Wadajkar, Aniket S, Lapidus, Rena G, Kim, Anthony J, Raub, Christopher B, Frenkel, Victor

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Novel, Broad Spectrum Anticancer Agents Containing the Tricyclic 5:7:5-Fused Diimidazodiazepine Ring System von Kondaskar, Atul, Kondaskar, Shilpi, Kumar, Raj, Fishbein, James C, Muvarak, Nidal, Lapidus, Rena G, Sadowska, Mariola, Edelman, Martin J, Bol, Guus M, Vesuna, Farhad, Raman, Venu, Hosmane, Ramachandra S

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