Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging von Freckmann, Eva C., Sandilands, Emma, Cumming, Erin, Neilson, Matthew, Román-Fernández, Alvaro, Nikolatou, Konstantina, Nacke, Marisa, Lannagan, Tamsin R. M., Hedley, Ann, Strachan, David, Salji, Mark, Morton, Jennifer P., McGarry, Lynn, Leung, Hing Y., Sansom, Owen J., Miller, Crispin J., Bryant, David M.

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Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis von Ng, Jia Q., Jafarov, Toghrul H., Little, Christopher B., Wang, Tongtong, Ali, Abdullah M., Ma, Yan, Radford, Georgette A., Vrbanac, Laura, Ichinose, Mari, Whittle, Samuel, Hunter, David J., Lannagan, Tamsin R. M., Suzuki, Nobumi, Goyne, Jarrad M., Kobayashi, Hiroki, Wang, Timothy C., Haynes, David R., Menicanin, Danijela, Gronthos, Stan, Worthley, Daniel L., Woods, Susan L., Mukherjee, Siddhartha

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Delineating proinflammatory microenvironmental signals by ex vivo modeling of the immature intestinal stroma von Ichinose, Mari, Suzuki, Nobumi, Wang, Tongtong, Wright, Josephine A., Lannagan, Tamsin R. M., Vrbanac, Laura, Kobayashi, Hiroki, Gieniec, Krystyna, Ng, Jia Q., Ihara, Souzaburo, Mavrangelos, Chris, Hayakawa, Yoku, Hughes, Patrick, Worthley, Daniel L., Woods, Susan L.

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BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer von Ramesh, Prashanthi, Lannagan, Tamsin R. M., Jackstadt, Rene, Atencia Taboada, Lidia, Lansu, Nico, Wirapati, Pratyaksha, van Hooff, Sander R., Dekker, Danielle, Pritchard, Jessica, Kirov, Aleksandar B., van Neerven, Sanne M., Tejpar, Sabine, Kops, Geert J. P. L., Sansom, Owen J., Medema, Jan Paul

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Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia von Gurbatri, Candice R., Radford, Georgette A., Vrbanac, Laura, Im, Jongwon, Thomas, Elaine M., Coker, Courtney, Taylor, Samuel R., Jang, YoungUk, Sivan, Ayelet, Rhee, Kyu, Saleh, Anas A., Chien, Tiffany, Zandkarimi, Fereshteh, Lia, Ioana, Lannagan, Tamsin R. M., Wang, Tongtong, Wright, Josephine A., Kobayashi, Hiroki, Ng, Jia Q., Lawrence, Matt, Sammour, Tarik, Thomas, Michelle, Lewis, Mark, Papanicolas, Lito, Perry, Joanne, Fitzsimmons, Tracy, Kaazan, Patricia, Lim, Amanda, Stavropoulos, Alexandra M., Gouskos, Dion A., Marker, Julie, Ostroff, Cheri, Rogers, Geraint, Arpaia, Nicholas, Worthley, Daniel L., Woods, Susan L., Danino, Tal

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MmCMS: mouse models’ consensus molecular subtypes of colorectal cancer von Amirkhah, Raheleh, Gilroy, Kathryn, Malla, Sudhir B., Lannagan, Tamsin R. M., Byrne, Ryan M., Fisher, Natalie C., Corry, Shania M., Mohamed, Noha-Ehssan, Naderi-Meshkin, Hojjat, Mills, Megan L., Campbell, Andrew D., Ridgway, Rachel A., Ahmaderaghi, Baharak, Murray, Richard, Llergo, Antoni Berenguer, Sanz-Pamplona, Rebeca, Villanueva, Alberto, Batlle, Eduard, Salazar, Ramon, Lawler, Mark, Sansom, Owen J., Dunne, Philip D.

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Co-inhibition of TGF-β and PD-L1 pathways in a metastatic colorectal cancer mouse model triggers interferon responses, innate cells and T cells, alongside metabolic changes and tum... von Nair, Reshmi, Lannagan, Tamsin R. M., Jackstadt, Rene, Andrusaite, Anna, Cole, John, Boyne, Caitlin, Nibbs, Robert J. B., Sansom, Owen J., Milling, Simon

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Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification von Kleeman, Sam O, Koelzer, Viktor H, Jones, Helen JS, Vazquez, Ester Gil, Davis, Hayley, East, James E, Arnold, Roland, Koppens, Martijn AJ, Blake, Andrew, Domingo, Enric, Cunningham, Chris, Beggs, Andrew D, Pestinger, Valerie, Loughrey, Maurice B, Wang, Lai-Mun, Lannagan, Tamsin RM, Woods, Susan L, Worthley, Daniel, Tomlinson, Ian, Dunne, Philip D, Maughan, Timothy, Leedham, Simon J

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Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia von Bond, Catherine E., Liu, Cheng, Kawamata, Futoshi, McKeone, Diane M., Fernando, Winnie, Jamieson, Saara, Pearson, Sally-Ann, Kane, Alexandra, Woods, Susan L., Lannagan, Tamsin R. M., Somashekar, Roshini, Lee, Young, Dumenil, Troy, Hartel, Gunter, Spring, Kevin J., Borowsky, Jennifer, Fennell, Lochlan, Bettington, Mark, Lee, Jason, Worthley, Daniel L., Leggett, Barbara A., Whitehall, Vicki L. J.

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Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development von Ichinose, Mari, Suzuki, Nobumi, Wang, Tongtong, Wright, Josephine A, Lannagan, Tamsin R M, Vrbanac, Laura, Kobayashi, Hiroki, Gieniec, Krystyna A, Ng, Jia Q, Hayakawa, Yoku, García-Gallastegui, Patricia, Monsalve, Eva M, Bauer, Steven R, Laborda, Jorge, García-Ramírez, J J, Ibarretxe, Gaskon, Worthley, Daniel L, Woods, Susan L

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Molecular Subtyping Resource: a user-friendly tool for rapid biological discovery from transcriptional data von Ahmaderaghi, Baharak, Amirkhah, Raheleh, Jackson, James, Lannagan, Tamsin R M, Gilroy, Kathryn, Malla, Sudhir B, Redmond, Keara L, Quinn, Gerard, McDade, Simon S, ACRCelerate Consortium, Maughan, Tim, Leedham, Simon, Campbell, Andrew S D, Sansom, Owen J, Lawler, Mark, Dunne, Philip D

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Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma von Kobayashi, Hiroki, Gieniec, Krystyna A., Ng, Jia Q., Goyne, Jarrad, Lannagan, Tamsin R. M., Thomas, Elaine M., Radford, Georgette, Wang, Tongtong, Suzuki, Nobumi, Ichinose, Mari, Wright, Josephine A., Vrbanac, Laura, Burt, Alastair D., Takahashi, Masahide, Enomoto, Atsushi, Worthley, Daniel L., Woods, Susan L.

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Medium-throughput Drug Screening of Patient-derived Organoids from Colorectal Peritoneal Metastases to Direct Personalized Therapy von Narasimhan, Vignesh, Wright, Josephine A, Churchill, Michael, Wang, Tongtong, Rosati, Rachele, Lannagan, Tamsin R M, Vrbanac, Laura, Richardson, Anne B, Kobayashi, Hiroki, Price, Timothy, Tye, Gayle X Y, Marker, Julie, Hewett, Peter J, Flood, Michael P, Pereira, Shalini, Whitney, G Adam, Michael, Michael, Tie, Jeanne, Mukherjee, Siddhartha, Grandori, Carla, Heriot, Alexander G, Worthley, Daniel L, Ramsay, Robert G, Woods, Susan L

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The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis von Kobayashi, Hiroki, Gieniec, Krystyna A., Lannagan, Tamsin R.M., Wang, Tongtong, Asai, Naoya, Mizutani, Yasuyuki, Iida, Tadashi, Ando, Ryota, Thomas, Elaine M., Sakai, Akihiro, Suzuki, Nobumi, Ichinose, Mari, Wright, Josephine A., Vrbanac, Laura, Ng, Jia Q., Goyne, Jarrad, Radford, Georgette, Lawrence, Matthew J., Sammour, Tarik, Hayakawa, Yoku, Klebe, Sonja, Shin, Alice E., Asfaha, Samuel, Bettington, Mark L., Rieder, Florian, Arpaia, Nicholas, Danino, Tal, Butler, Lisa M., Burt, Alastair D., Leedham, Simon J., Rustgi, Anil K., Mukherjee, Siddhartha, Takahashi, Masahide, Wang, Timothy C., Enomoto, Atsushi, Woods, Susan L., Worthley, Daniel L.

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Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia von Vasquez, Ester Gil, Nasreddin, Nadia, Valbuena, Gabriel N., Mulholland, Eoghan J., Belnoue-Davis, Hayley L., Eggington, Holly R., Schenck, Ryan O., Wouters, Valérie M., Wirapati, Pratyaksha, Gilroy, Kathryn, Lannagan, Tamsin R.M., Flanagan, Dustin J., Najumudeen, Arafath K., Omwenga, Sulochana, McCorry, Amy M.B., Easton, Alistair, Koelzer, Viktor H., East, James E., Morton, Dion, Trusolino, Livio, Maughan, Timothy, Campbell, Andrew D., Loughrey, Maurice B., Dunne, Philip D., Tsantoulis, Petros, Huels, David J., Tejpar, Sabine, Sansom, Owen J., Leedham, Simon J.

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Advances in colon cancer research: in vitro and animal models von Lannagan, Tamsin RM, Jackstadt, Rene, Leedham, Simon J, Sansom, Owen J

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Prokineticins: novel mediators of inflammatory and contractile pathways at parturition? von Catalano, Rob D., Lannagan, Tamsin R.M., Gorowiec, Marta, Denison, Fiona C., Norman, Jane E., Jabbour, Henry N.

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The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses von Ichinose, Mari, Suzuki, Nobumi, Wang, Tongtong, Kobayashi, Hiroki, Vrbanac, Laura, Ng, Jia Q., Wright, Josephine A., Lannagan, Tamsin R. M., Gieniec, Krystyna A., Lewis, Martin, Ando, Ryota, Enomoto, Atsushi, Koblar, Simon, Thomas, Paul, Worthley, Daniel L., Woods, Susan L.

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Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis von Lannagan, Tamsin R M, Lee, Young K, Wang, Tongtong, Roper, Jatin, Bettington, Mark L, Fennell, Lochlan, Vrbanac, Laura, Jonavicius, Lisa, Somashekar, Roshini, Gieniec, Krystyna, Yang, Miao, Ng, Jia Q, Suzuki, Nobumi, Ichinose, Mari, Wright, Josephine A, Kobayashi, Hiroki, Putoczki, Tracey L, Hayakawa, Yoku, Leedham, Simon J, Abud, Helen E, Yilmaz, Ömer H, Marker, Julie, Klebe, Sonja, Wirapati, Pratyaksha, Mukherjee, Siddhartha, Tejpar, Sabine, Leggett, Barbara A, Whitehall, Vicki L J, Worthley, Daniel L, Woods, Susan L

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Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia von Gil Vazquez, Ester, Nasreddin, Nadia, Valbuena, Gabriel N., Mulholland, Eoghan J., Belnoue-Davis, Hayley L., Eggington, Holly R., Schenck, Ryan O., Wouters, Valérie M., Wirapati, Pratyaksha, Gilroy, Kathryn, Lannagan, Tamsin R.M., Flanagan, Dustin J., Najumudeen, Arafath K., Omwenga, Sulochana, McCorry, Amy M.B., Easton, Alistair, Koelzer, Viktor H., East, James E., Morton, Dion, Trusolino, Livio, Maughan, Timothy, Campbell, Andrew D., Loughrey, Maurice B., Dunne, Philip D., Tsantoulis, Petros, Huels, David J., Tejpar, Sabine, Sansom, Owen J., Leedham, Simon J.

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