Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration von Sleiman, Sama F, Langley, Brett C, Basso, Manuela, Berlin, Jill, Xia, Li, Payappilly, Jimmy B, Kharel, Madan K, Guo, Hengchang, Marsh, J Lawrence, Thompson, Leslie Michels, Mahishi, Lata, Ahuja, Preeti, MacLellan, W Robb, Geschwind, Daniel H, Coppola, Giovanni, Rohr, Jürgen, Ratan, Rajiv R

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Functional Differences in Epigenetic ModulatorsSuperiority of Mercaptoacetamide-Based Histone Deacetylase Inhibitors Relative to Hydroxamates in Cortical Neuron Neuroprotection Stu... von Kozikowski, Alan P., Chen, Yufeng, Gaysin, Arsen, Chen, Bin, D'Annibale, Melissa A., Suto, Carla M., Langley, Brett C.

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Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease von McConoughey, Stephen J., Basso, Manuela, Niatsetskaya, Zoya V., Sleiman, Sama F., Smirnova, Natalia A., Langley, Brett C., Mahishi, Lata, Cooper, Arthur J. L., Antonyak, Marc A., Cerione, Rick A., Li, Bo, Starkov, Anatoly, Chaturvedi, Rajnish Kumar, Beal, M. Flint, Coppola, Giovanni, Geschwind, Daniel H., Ryu, Hoon, Xia, Li, Iismaa, Siiri E., Pallos, Judit, Pasternack, Ralf, Hils, Martin, Fan, Jing, Raymond, Lynn A., Marsh, J. Lawrence, Thompson, Leslie M., Ratan, Rajiv R.

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Searching for Disease Modifiers - PKC Activation and HDAC Inhibition - A Dual Drug Approach to Alzheimer's Disease that Reduces Aβ Production while Blocking Oxidative Stress von Kozikowski, Alan P., Chen, Yihua, Subhasish, Tapadar, Lewin, Nancy E., Blumberg, Peter M., Zhong, Zhenyu, D'Annibale, Melissa A., Wang, Weng-Long, Shen, Yong, Langley, Brett C.

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Compounds for Enhancing p21 Expression and Methods of Use Thereof von RATAN RAJIV R, LANGLEY BRETT C, KO BRIAN S

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Respiratory Syncytial Virus-Associated Hospitalizations Among Young Children: 2015-2016 von Rha, Brian, Curns, Aaron T., Lively, Joana Y., Campbell, Angela P., Englund, Janet A., Boom, Julie A., Azimi, Parvin H., Weinberg, Geoffrey A., Staat, Mary A., Selvarangan, Rangaraj, Halasa, Natasha B., McNeal, Monica M., Klein, Eileen J., Harrison, Christopher J., Williams, John V., Szilagyi, Peter G., Singer, Monica N., Sahni, Leila C., Figueroa-Downing, Daniella, McDaniel, Darius, Prill, Mila M., Whitaker, Brett L., Stewart, Laura S., Schuster, Jennifer E., Pahud, Barbara A., Weddle, Gina, Avadhanula, Vasanthi, Munoz, Flor M., Piedra, Pedro A., Payne, Daniel C., Langley, Gayle, Gerber, Susan I.

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Discriminative Value of Inflammatory Biomarkers for Suspected Sepsis von Tsalik, Ephraim L., MD, PhD, Jaggers, L. Brett, MD, Glickman, Seth W., MD, Langley, Raymond J., PhD, van Velkinburgh, Jennifer C., PhD, Park, Lawrence P., PhD, Fowler, Vance G., MD, Cairns, Charles B., MD, Kingsmore, Stephen F., MB, CHB, BAO, DSC, Woods, Christopher W., MD, MPH

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Myostatin, a Negative Regulator of Muscle Growth, Functions by Inhibiting Myoblast Proliferation von Thomas, Mark, Langley, Brett, Berry, Carole, Sharma, Mridula, Kirk, Sonnie, Bass, John, Kambadur, Ravi

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Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway von Haskew-Layton, Renée E., Payappilly, Jimmy B., Smirnova, Natalya A., Ma, Thong C., Chan, Kelvin K., Murphy, Timothy H., Guo, Hengchang, Langley, Brett, Sultana, Rukhsana, Butterfield, D. Allan, Santagata, Sandro, Alldred, Melissa J., Gazaryan, Irina G., Bell, George W., Ginsberg, Stephen D., Ratan, Rajiv R.

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Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical Research von Langley, Gill, Austin, Christopher P, Balapure, Anil K, Birnbaum, Linda S, Bucher, John R, Fentem, Julia, Fitzpatrick, Suzanne C, Fowle, 3rd, John R, Kavlock, Robert J, Kitano, Hiroaki, Lidbury, Brett A, Muotri, Alysson R, Peng, Shuang-Qing, Sakharov, Dmitry, Seidle, Troy, Trez, Thales, Tonevitsky, Alexander, van de Stolpe, Anja, Whelan, Maurice, Willett, Catherine

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Chemotherapy for the Brain: The Antitumor Antibiotic Mithramycin Prolongs Survival in a Mouse Model of Huntington's Disease von Ferrante, Robert J, Ryu, Hoon, Kubilus, James K, D'Mello, Santosh, Sugars, Katharine L, Lee, Junghee, Lu, Peiyuan, Smith, Karen, Browne, Susan, Beal, M. Flint, Kristal, Bruce S, Stavrovskaya, Irina G, Hewett, Sandra, Rubinsztein, David C, Langley, Brett, Ratan, Rajiv R

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Respiratory Virus Surveillance Among Children with Acute Respiratory Illnesses - New Vaccine Surveillance Network, United States, 2016-2021 von Perez, Ariana, Lively, Joana Y, Curns, Aaron, Weinberg, Geoffrey A, Halasa, Natasha B, Staat, Mary Allen, Szilagyi, Peter G, Stewart, Laura S, McNeal, Monica M, Clopper, Benjamin, Zhou, Yingtao, Whitaker, Brett L, LeMasters, Elizabeth, Harker, Elizabeth, Englund, Janet A, Klein, Eileen J, Selvarangan, Rangaraj, Harrison, Christopher J, Boom, Julie A, Sahni, Leila C, Michaels, Marian G, Williams, John V, Langley, Gayle E, Gerber, Susan I, Campbell, Angela, Hall, Aron J, Rha, Brian, McMorrow, Meredith

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Respiratory Syncytial Virus-Associated Hospitalizations Among Children <5 Years Old: 2016 to 2020 von Curns, Aaron T, Rha, Brian, Lively, Joana Y, Sahni, Leila C, Englund, Janet A, Weinberg, Geoffrey A, Halasa, Natasha B, Staat, Mary A, Selvarangan, Rangaraj, Michaels, Marian, Moline, Heidi, Zhou, Yingtao, Perez, Ariana, Rohlfs, Chelsea, Hickey, Robert, Lacombe, Kirsten, McHenry, Rendie, Whitaker, Brett, Schuster, Jennifer, Pulido, Claudia Guevara, Strelitz, Bonnie, Quigley, Christina, Dnp, Gina Weddle, Avadhanula, Vasanthi, Harrison, Christopher J, Stewart, Laura S, Schlaudecker, Elizabeth, Szilagyi, Peter G, Klein, Eileen J, Boom, Julie, Williams, John V, Langley, Gayle, Gerber, Susan I, Hall, Aron J, McMorrow, Meredith L

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Epigenetics in the Nervous System von Jiang, Yan, Langley, Brett, Lubin, Farah D, Renthal, William, Wood, Marcelo A, Yasui, Dag H, Kumar, Arvind, Nestler, Eric J, Akbarian, Schahram, Beckel-Mitchener, Andrea C

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Challenges With Left Ventricular Functional Parameters: The Pediatric Heart Network Normal Echocardiogram Database von Minich, L. LuAnn, Altmann, Karen, Camarda, Joseph, Cohen, Meryl S., Colan, Steven D., Dragulescu, Andreea, Frommelt, Michele A., Johnson, Tiffanie R., Kovalchin, John P., Lin, Lina, Mahgerefteh, Joseph, Nutting, Arni, Pearson, Gail D., Sachdeva, Ritu, Statile, Christopher J., Tierney, E. Seda, Lopez, Leo, Burns, Kristin, Stylianou, Mario, Mahony, Lynn, Chen, Shan, Gongwer, Russell, Granger, Suzanne, Keosaian, Julia, Langley, Susanne, Lin, Lina, Mansolf, Tammi, Moine, Stephanie, Morrison, Andrew, Nelson, Katelyn, Ni, Brenda, Ortiz, Janet, Pucillo, Michelle, Stark, Paul, Trachtenberg, Felicia, Winrich, Barbara, McCrindle, Brian, Dragulescu, Andreea, Radojewski, Elizabeth, Mital, Seema, Walter, Patricia, Slorach, Cameron, Newburger, Jane, Levine, Jami, Paridon, Stephen, Cohen, Meryl, Goldberg, David, Morrison, Tonia, Chowdhury, Shahryar, Infinger, Patricia, LuAnn Minich, L., Truong, Dongngan T., Lambert, Linda M., Shearrow, Marian E., Stanton, Belva, Goldberg, Caren, Welch, Suzanne, Cnota, James F., Ash, Kathleen, Sticka, Joshua, Payne, Mark, Cordes, Timothy, Swan, Liz, Friedman, Heather S., Clark, Laurie J., Sachdeva, Ritu, Penny, Daniel, Pignatelli, Ricardo, Lai, Wyman, Anderson, Brett, Thankavel, Poonam Punjwani, Carron, Hollie, Ginde, Salil, Frommelt, Michele, Markham, Larry, Parra, David A., Soslow, Jonathan H., Young, Luciana, Camarda, Joseph, Van't Hof, Kathleen, Lewin, Mark, Lester, Joel, Bhat, Aarti H., Payne, Amy, Srivastava, Shubhika, Lytrivi, Irene, Ko, Helen, Mahgerefteh, Joseph, Lopez, Leo, Balem, Kelly Ann, Sable, Craig, Stelter, Jessica, Artman, Michael, Rao, Anu, Johnson, Julie, Krischer, Jeffrey P., Kugler, John, Driscoll, David, Hunsberger, Sally, Taylor, Holly

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A screen for inducers of p21(waf1/cip1) identifies HIF prolyl hydroxylase inhibitors as neuroprotective agents with antitumor properties von Ma, Thong C, Langley, Brett, Ko, Brian, Wei, Na, Gazaryan, Irina G, Zareen, Neela, Yamashiro, Darrell J, Willis, Dianna E, Ratan, Rajiv R

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Respiratory Syncytial Virus Infection Among Hospitalized Infants in Four Middle-Income Countries von Biggs, Holly M, Simões, Eric A F, Abu Khader, Ilham, Thompson, Mark G, Gordon, Aubree, Hunt, Danielle R, DeGroote, Nicholas P, Porter, Rachael M, Bino, Silvia, Marar, Basima I, Gresh, Lionel, de Jesus-Cornejo, Joanne, Langley, Gayle, Thornburg, Natalie J, Peret, Teresa C T, Whitaker, Brett, Zhang, Yange, Wang, Lijuan, Patel, Mira C, McMorrow, Meredith, Campbell, William, Hasibra, Iris, Duka, Enkeleda, Al-Gazo, Mahmoud, Kubale, John, Sanchez, Felix, Lucero, Marilla G, Tallo, Veronica L, Azziz-Baumgartner, Eduardo, Simaku, Artan, Gerber, Susan I

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Myostatin inhibits rhabdomyosarcoma cell proliferation through an Rb-independent pathway von LANGLEY, Brett, THOMAS, Mark, MCFARLANE, Craig, GILMOUR, Stewart, SHARMA, Mridula, KAMBADUR, Ravi

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Titin-cap associates with, and regulates secretion of, Myostatin von Nicholas, Gina, Thomas, Mark, Langley, Brett, Somers, Wayne, Patel, Ketan, Kemp, C. Fred, Sharma, Mridula, Kambadur, Ravi

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Proteolytic processing of myostatin is auto-regulated during myogenesis von McFarlane, Craig, Langley, Brett, Thomas, Mark, Hennebry, Alex, Plummer, Erin, Nicholas, Gina, McMahon, Chris, Sharma, Mridula, Kambadur, Ravi

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