Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities von LANGLAND, Gregory T, YANNONE, Steven M, LANGLAND, Rachel A, NAKAO, Aki, GUAN, Yinghui, LONG, Sydney B. T, VONGUYEN, Lien, CHEN, David J, GRAY, Joe W, FANQING CHEN

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Abstract C24: Detection of BRAFV600E in cell free DNA from patients with papillary thyroid cancer von Sherman, Eric, Cohen, Ezra E.W., Cabanillas, Maria E., Gianoukakis, Andrew, Tai, Yu Chuan, Langland, Rachel A., Brose, Marcia S.

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Differential expression of AP-2γ and AP-2α during human trophoblast differentiation von Richardson, Brian D., Cheng, You-Hong, Langland, Rachel A., Handwerger, Stuart

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Analytical Performance of a Real-time PCR-based Assay for V600 Mutations in the BRAF Gene, Used as the Companion Diagnostic Test for the Novel BRAF Inhibitor Vemurafenib in Metasta... von Halait, Harkanwal, DeMartin, Kelli, Shah, Sweta, Soviero, Stephen, Langland, Rachel, Cheng, Suzanne, Hillman, Grantland, Wu, Lin, Lawrence, H Jeffrey

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Multisite analytic performance studies of a real-time polymerase chain reaction assay for the detection of BRAF V600E mutations in formalin-fixed, paraffin-embedded tissue specimen... von Anderson, Steven, Bloom, Kenneth J, Vallera, Dino U, Rueschoff, Josef, Meldrum, Cliff, Schilling, Robert, Kovach, Barbara, Lee, Ju Ruey-Jiuan, Ochoa, Pam, Langland, Rachel, Halait, Harkanwal, Lawrence, H Jeffrey, Dugan, Michael C

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Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results von Youssef, Eriene A, Berry-Kravis, Elizabeth, Czech, Christian, Hagerman, Randi J, Hessl, David, Wong, Chin Y, Rabbia, Michael, Deptula, Dennis, John, Amy, Kinch, Russell, Drewitt, Philip, Lindemann, Lothar, Marcinowski, Moritz, Langland, Rachel, Horn, Carsten, Fontoura, Paulo, Santarelli, Luca, Quiroz, Jorge A

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A sensitive and accurate test for simultaneous detection of 36 BRAF and NRAS mutations von Patten, Nancy, Brophy, Victoria H., Hui, Winnie, Langland, Rachel Anne

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HLA-DQA105 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn’s Disease von Kennedy, Nicholas A., Moutsianas, Loukas, Heap, Graham A., Chanchlani, Neil, Walker, Gareth J., Perry, Mandy H., Lees, Charlie W., Parkes, Miles, Mansfield, John C., McGovern, Dermot, Ahmad, Tariq, Patel, Vinod, Mazhar, Zia, Colleypriest, Ben, Weaver, Sean, Preston, Cathryn, Butt, Assad, Smith, Melissa, Beale, Amanda, Langlands, Sarah, Direkze, Natalie, Torrente, Franco, De La Revella Negro, Juan, Ewen MacDonald, Chris, Evans, Stephen M, Gunasekera, Anton V J, Thakur, Alka, Elphick, David, Shenoy, Achuth, Agrawal, Anurag, Bridger, Stephen, Cooper, Sheldon C, de Silva, Shanika, Mowat, Craig, Mayhead, Phillip, Lees, Charlie, Ahmad, Tariq, Russell, Richard K, Gervais, Lisa, Dunckley, Paul, Mahmood, Tariq, Banim, Paul J R, Sonwalkar, Sunil, Ghosh, Deb, Phillips, Rosemary H, Azaz, Amer, Sebastian, Shaji, Shenderey, Richard, Armstrong, Lawrence, Bell, Claire, Hariraj, Radhakrishnan, Matthews, Helen, Jafferbhoy, Hasnain, Selinger, Christian P, Willmott, Anne, Bloom, Stuart L, Chung-Faye, Guy, Harbord, Marcus, Hart, Ailsa, Lindsay, James O, Mawdsley, Joel E, McNair, Alistair, Murray, Charles D, Paul, Thankam, Pollok, Richard, Shah, Neil, Johnson, Matt W, Modi, Anita, Dawa Kabiru, Kasamu, Baburajan, B K, Bhaduri, Bim, Adebayo Fagbemi, Andrew, Limdi, Jimmy K, Ramadas, Arvind, MacFaul, George, Mansfield, John, Morris, Mary-Anne, Tremelling, Mark, Hawkey, Chris, Charlton, Charles PJ, Rodrigues, Astor, Snook, Jonathon, De Silva, Aminda N, Smith, Mark S, Panter, Simon, Cummings, Fraser, Mahmood, Zahid, Sen, Sandip, Pigott, Anna J, Hobday, David, Wesley, Emma, Beckly, John, Vani, Deven, Ramakrishnan, Subramaniam, Chaudhary, Rakesh, Trudgill, Nigel J, Cooney, Rachel, Bell, Andy, Li, Andy, Gore, Stephen

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Comparison of testing methods for the detection of BRAF V600E mutations in malignant melanoma: pre-approval validation study of the companion diagnostic test for vemurafenib von Lopez-Rios, Fernando, Angulo, Barbara, Gomez, Belen, Mair, Debbie, Martinez, Rebeca, Conde, Esther, Shieh, Felice, Vaks, Jeffrey, Langland, Rachel, Lawrence, H Jeffrey, de Castro, David Gonzalez

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Optimizing targeted therapeutic development: Analysis of a colorectal cancer patient population with the BRAFV600E mutation von Tie, Jeanne, Gibbs, Peter, Lipton, Lara, Christie, Michael, Jorissen, Robert N., Burgess, Antony W., Croxford, Matthew, Jones, Ian, Langland, Rachel, Kosmider, Suzanne, McKay, Daniel, Bollag, Gideon, Nolop, Keith, Sieber, Oliver M., Desai, Jayesh

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Optimizing targeted therapeutic development: analysis of a colorectal cancer patient population with the BRAF(V600E) mutation von Tie, Jeanne, Gibbs, Peter, Lipton, Lara, Christie, Michael, Jorissen, Robert N, Burgess, Antony W, Croxford, Matthew, Jones, Ian, Langland, Rachel, Kosmider, Suzanne, McKay, Daniel, Bollag, Gideon, Nolop, Keith, Sieber, Oliver M, Desai, Jayesh

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Characterization of WU-CART-007, an Allogeneic CD7-Targeted CAR-T Cell Therapy for T-Cell Malignancies von Leedom, Tom, Hamil, Alexander S., Pouyanfard, Somayeh, Govero, Jennifer, Langland, Rachel, Ballard, Anna, Schwarzkopf, Liz, Martens, Andrew, Espenschied, Andrew, Vinay, Pooja, James, Michael, Mahajan, Nitin, Spencer, David H, Chrobak, Kenneth M, Cooper, Matthew L, Kabakibi, Ayman

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Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study von Kennedy, Nicholas A, Heap, Graham A, Green, Harry D, Hamilton, Benjamin, Bewshea, Claire, Thomas, Amanda, Nice, Rachel, Perry, Mandy H, Bouri, Sonia, Heerasing, Neel M, Lin, Simeng, Gaya, Daniel R, Cummings, J R Fraser, Hart, Ailsa L, Parkes, Miles, Sebastian, Shaji, Mansfield, John C, Goodhand, James R, Ahmad, Tariq, Patel, Vinod, Mazhar, Zia, Saich, Rebecca, Colleypriest, Ben, Tham, Tony C, Iqbal, Tariq H, Kaushik, Vishal, Murugesan, Senthil, Weaver, Sean, Butt, Assad, Basude, Dharamveer, Parkes, Miles, Evans, Stephen M, Gunasekera, Anton V J, Thakur, Alka, Shenoy, Achuth, Cooper, Sheldon C, de Silva, Shanika, Mowat, Craig, Lees, Charlie, Jones, Gareth, Ahmad, Tariq, Gaya, Daniel R, Russell, Richard K, Sonwalkar, Sunil, Ghosh, Deb, Phillips, Rosemary H, Azaz, Amer, Sebastian, Shaji, Shenderey, Richard, Armstrong, Lawrence, Hariraj, Radhakrishnan, Matthews, Helen, Jafferbhoy, Hasnain, Selinger, Christian P, Miller, Richard, Tzivinikos, Christos, Chung-Faye, Guy, Croft, Nicholas M, Harbord, Marcus, Lindsay, James O, Mawdsley, Joel E, McNair, Alistair, Monahan, Kevin J, Murray, Charles D, Paul, Thankam, Pollok, Richard, Shah, Neil, Johnson, Matt W, Kabiru, Kasamu Dawa, Baburajan, B K, Bhaduri, Bim, Limdi, Jimmy K, Watts, Gill, Foley, Stephen, Ramadas, Arvind, MacFaul, George, Grellier, Leonie, Morris, Mary-Anne, Tremelling, Mark, Hawkey, Chris, Rodrigues, Astor, Simmons, Alison, Lewis, Stephen J, Tighe, Mark, Goggin, Patrick M, De Silva, Aminda N, Smith, Mark S, Panter, Simon, Mahmood, Zahid, McLain, Bruce, Sen, Sandip, Pigott, Anna J, Hobday, David, Johnston, Richard, Beckly, John, Vani, Deven, Chaudhary, Rakesh, Cooney, Rachel, Bell, Andy, Brookes, Matthew J

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Repression of organizer genes in dorsal and ventral Xenopus cells mediated by maternal XTcf3 von Houston, Douglas W, Kofron, Matt, Resnik, Ernesto, Langland, Rachel, Destree, Olivier, Wylie, Christopher, Heasman, Janet

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Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients von Bai, Benjamin Y H, Reppell, Mark, Smaoui, Nizar, Waring, Jeffrey F, Pivorunas, Valerie, Guay, Heath, Lin, Simeng, Chanchlani, Neil, Bewshea, Claire, Goodhand, James R, Kennedy, Nicholas A, Ahmad, Tariq, Anderson, Carl A

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Mechanisms and management of loss of response to anti-TNF therapy for patients with Crohn's disease: 3-year data from the prospective, multicentre PANTS cohort study von Bewshea, Claire, Thomas, Amanda, Roberts, Christopher, Bishara, Maria, Nice, Rachel, Lees, Charlie W, Sebastian, Shaji, Irving, Peter M, Russell, Richard K, McDonald, Timothy J, Goodhand, James R, Ahmad, Tariq, Mazhar, Zia, Saich, Rebecca, Colleypriest, Ben, Tham, Tony C, Iqbal, Tariq, Kaushik, Vishal, Murugesan, Senthil, Singh, Salil, Weaver, Sean, Butt, Assad, Smith, Melissa, Basude, Dharamveer, Beale, Amanda, Langlands, Sarah, Direkze, Natalie, Parkes, Miles, Torrente, Franco, MacDonald, Chris Ewen, Evans, Stephen M, Gunasekera, Anton VJ, Elphick, David, Nwokolo, Chuka U, Cole, Andrew T, Doherty, Julie, Cooper, Sheldon C, Mowat, Craig, Mayhead, Phillip, Ahmad, Tariq, Hart, James W, Kennedy, Nicholas A, McDonald, Timothy J, Greenish, Huw, Heath, Harry, Gaya, Daniel R, Russell, Richard K, Sonwalkar, Sunil, Ghosh, Deb, Phillips, Rosemary H, Azaz, Amer, Sebastian, Shaji, Shenderey, Richard, Armstrong, Lawrence, Hariraj, Radhakrishnan, Matthews, Helen, Jafferbhoy, Hasnain, Selinger, Christian P, Miller, Richard, Tzivinikos, Christos, Chung-Faye, Guy, Croft, Nicholas M, Harbord, Marcus, Lindsay, James O, Mawdsley, Joel E, McNair, Alistair, Monahan, Kevin J, Murray, Charles D, Pollok, Richard, Shah, Neil, Johnson, Matt W, Kabiru, Kasamu Dawa, Baburajan, B K, Bhaduri, Bim, Watts, Gill, Foley, Stephen, Ramadas, Arvind, MacFaul, George, Grellier, Leonie, Morris, Mary-Anne, Tremelling, Mark, Hawkey, Chris, Rodrigues, Astor, Simmons, Alison, Tighe, Mark, Goggin, Patrick M, De Silva, Aminda N, Smith, Mark S, Panter, Simon, Mahmood, Zahid, McLain, Bruce, Sen, Sandip, Pigott, Anna J, Hobday, David, Johnston, Richard, Beckly, John, Chaudhary, Rakesh, Cooney, Rachel, Bell, Andy, Brookes, Matthew J

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Vegetal Localization of Maternal mRNAs Is Disrupted by VegT Depletion von Heasman, Janet, Wessely, Oliver, Langland, Rachel, Craig, Eileen J., Kessler, Daniel S.

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Abstract 2212: The analytic performance of a real-time PCR-based assay for the BRAF V600E mutation used as the companion diagnostic test for the novel BRAF inhibitor RG7204 (PLX403... von Halait, Harkanwal, DeMartin, Kelli, Shah, Sweta, Soviero, Stephen, Langland, Rachel, Cheng, Suzanne, Hillman, Grantland, Wu, Lin, Lawrence, Jeffrey

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Optimizing targeted therapeutic development: Analysis of a colorectal cancer patient population with the BRAF V600E mutation von Tie, Jeanne, Gibbs, Peter, Lipton, Lara, Christie, Michael, Jorissen, Robert N., Burgess, Antony W., Croxford, Matthew, Jones, Ian, Langland, Rachel, Kosmider, Suzanne, McKay, Daniel, Bollag, Gideon, Nolop, Keith, Sieber, Oliver M., Desai, Jayesh

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Diagnostic test for susceptibility to b-raf kinase inhibitors von WILL STEPHEN, WU LIN, SHARP THAD, LANGLAND RACHEL

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