The potential of PARP as a therapeutic target across pediatric solid malignancies von Keller, Kaylee M, Koetsier, Joost, Schild, Linda, Amo-Addae, Vicky, Eising, Selma, van den Handel, Kim, Ober, Kimberley, Koopmans, Bianca, Essing, Anke, van den Boogaard, Marlinde L, Langenberg, Karin P S, Jäger, Natalie, Kool, Marcel, Pfister, Stefan, Dolman, M Emmy M, Molenaar, Jan J, van Hooff, Sander R

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Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes von Meister, Michael T, Groot Koerkamp, Marian J A, de Souza, Terezinha, Breunis, Willemijn B, Frazer‐Mendelewska, Ewa, Brok, Mariël, DeMartino, Jeff, Manders, Freek, Calandrini, Camilla, Kerstens, Hinri H D, Janse, Alex, Dolman, M Emmy M, Eising, Selma, Langenberg, Karin P S, van Tuil, Marc, Knops, Rutger R G, van Scheltinga, Sheila Terwisscha, Hiemcke‐Jiwa, Laura S, Flucke, Uta, Merks, Johannes H M, van Noesel, Max M, Tops, Bastiaan B J, Hehir‐Kwa, Jayne Y, Kemmeren, Patrick, Molenaar, Jan J, van de Wetering, Marc, van Boxtel, Ruben, Drost, Jarno, Holstege, Frank C P

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Myeloproliferative Neoplasm Driven by ETV6-ABL1 in an Adolescent with Recent History of Burkitt Leukemia von Renzi, Samuele, Algawahmed, Fatimah, Davidson, Scott, Langenberg, Karin P S, Fuligni, Fabio, Ali, Salah, Anderson, Nathaniel, Brunga, Ledia, Bartram, Jack, Abdelhaleem, Mohamed, Naqvi, Ahmed, Beimnet, Kassa, Schuh, Andre, Tierens, Anne, Malkin, David, Shlien, Adam, Shago, Mary, Villani, Anita

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Assessment of Cancer Predisposition Syndromes in a National Cohort of Children With a Neoplasm von Bakhuizen, Jette J, Hopman, Saskia M J, Bosscha, Machteld I, Dommering, Charlotte J, van den Heuvel-Eibrink, Marry M, Hol, Janna A, Kester, Lennart A, Koudijs, Marco J, Langenberg, Karin P S, Loeffen, Jan L C, van der Lugt, Jasper, Moll, Annette C, van Noesel, Max M, Smetsers, Stephanie E, de Vos-Kerkhof, Evelien, Merks, Johannes H M, Kuiper, Roland P, Jongmans, Marjolijn C J

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Oncogenic and immunological targets for matched therapy of pediatric blood cancer patients: Dutch iTHER study experience von Boer, Judith M., Ilan, Uri, Boeree, Aurélie, Langenberg, Karin P. S., Koster, Jan, Koudijs, Marco J., Hehir‐Kwa, Jayne Y., Nierkens, Stefan, Rossi, Corinne, Molenaar, Jan J., Goemans, Bianca F., Boer, Monique L., Zwaan, C. Michel

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mRNA Expression Level of ALK in Neuroblastoma Is Associated with Histological Subtype, ALK Mutations and ALK Immunohistochemical Protein Expression von Bruinsma, Rixt S., Fiocco, Marta F., de Leng, Wendy W. J., Kester, Lennart A., Langenberg, Karin P. S., Tytgat, Godelieve A. M., van Noesel, Max M., Wijnen, Marc H. W. A., van der Steeg, Alida F. W., de Krijger, Ronald R.

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The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets von van Tilburg, Cornelis M., Pfaff, Elke, Pajtler, Kristian W., Langenberg, Karin P. S., Fiesel, Petra, Jones, Barbara C., Balasubramanian, Gnana Prakash, Stark, Sebastian, Johann, Pascal D., Blattner-Johnson, Mirjam, Schramm, Kathrin, Dikow, Nicola, Hirsch, Steffen, Sutter, Christian, Grund, Kerstin, von Stackelberg, Arend, Kulozik, Andreas E., Lissat, Andrej, Borkhardt, Arndt, Meisel, Roland, Reinhardt, Dirk, Klusmann, Jan-Henning, Fleischhack, Gudrun, Tippelt, Stephan, von Schweinitz, Dietrich, Schmid, Irene, Kramm, Christof M., von Bueren, Andre O., Calaminus, Gabriele, Vorwerk, Peter, Graf, Norbert, Westermann, Frank, Fischer, Matthias, Eggert, Angelika, Burkhardt, Birgit, Woessmann, Wilhelm, Nathrath, Michaela, Hecker-Nolting, Stefanie, Fruehwald, Michael C., Schneider, Dominik T., Brecht, Ines B., Ketteler, Petra, Fulda, Simone, Koscielniak, Ewa, Meister, Michael T., Scheer, Monika, Hettmer, Simone, Schwab, Matthias, Tremmel, Roman, Ora, Ingrid, Hutter, Caroline, Gerber, Nicolas U., Lohi, Olli, Kazanowska, Bernarda, Kattamis, Antonis, Filippidou, Maria, Goemans, Bianca, Zwaan, C. Michel, Milde, Till, Jaeger, Natalie, Wolf, Stephan, Reuss, David, Sahm, Felix, von Deimling, Andreas, Dirksen, Uta, Freitag, Angelika, Witt, Ruth, Lichter, Peter, Kopp-Schneider, Annette, Jones, David T. W., Molenaar, Jan J., Capper, David, Pfister, Stefan M., Witt, Olaf

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The Landscape of Pediatric Precision Oncology: Program Design, Actionable Alterations, and Clinical Trial Development von Langenberg, Karin P. S., Looze, Eleonora J., Molenaar, Jan J.

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Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors von Calandrini, Camilla, van Hooff, Sander R., Paassen, Irene, Ayyildiz, Dilara, Derakhshan, Sepide, Dolman, M. Emmy M., Langenberg, Karin P.S., van de Ven, Marieke, de Heus, Cecilia, Liv, Nalan, Kool, Marcel, de Krijger, Ronald R., Tytgat, Godelieve A.M., van den Heuvel-Eibrink, Marry M., Molenaar, Jan J., Drost, Jarno

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Paternal exposure to recreational drugs before conception and its effect on live‐born offspring: A scoping review von Verstegen, Ruud H.J., Wang, Guo, Langenberg‐Ververgaert, Karin P.S., Ren, Lily Yuxi, Nulman, Irena

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Case series on clinical applications of liquid biopsy in pediatric solid tumors: towards improved diagnostics and disease monitoring von Gelineau, Nina U, van Barneveld, Astrid, Samim, Atia, Van Zogchel, Lieke, Lak, Nathalie, Tas, Michelle L, Matser, Yvette, Mavinkurve-Groothuis, Annelies M C, van Grotel, Martine, Zsiros, Jószef, van Eijkelenburg, Natasha K A, Knops, Rutger R G, van Ewijk, Roelof, Langenberg, Karin P S, Krijger, Ronald De, Hiemcke-Jiwa, Laura S, Van Paemel, Ruben, Cornelli, Lotte, De Preter, Katleen, De Wilde, Bram, Van Der Schoot, Ellen, Tytgat, Godelieve

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Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell von Kildisiute, Gerda, Kholosy, Waleed M., Young, Matthew D., Roberts, Kenny, Elmentaite, Rasa, van Hooff, Sander R., Pacyna, Clarissa N., Khabirova, Eleonora, Piapi, Alice, Thevanesan, Christine, Bugallo-Blanco, Eva, Burke, Christina, Mamanova, Lira, Keller, Kaylee M., Langenberg-Ververgaert, Karin P. S., Lijnzaad, Philip, Margaritis, Thanasis, Holstege, Frank C. P., Tas, Michelle L., Wijnen, Marc H. W. A., van Noesel, Max M., Del Valle, Ignacio, Barone, Giuseppe, van der Linden, Reinier, Duncan, Catriona, Anderson, John, Achermann, John C., Haniffa, Muzlifah, Teichmann, Sarah A., Rampling, Dyanne, Sebire, Neil J., He, Xiaoling, de Krijger, Ronald R., Barker, Roger A., Meyer, Kerstin B., Bayraktar, Omer, Straathof, Karin, Molenaar, Jan J., Behjati, Sam

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Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry... von Heipertz, AE, Pajtler, KW, Pfaff, E, Schramm, K, Blattner-Johnson, M, Milde, T, Jones, BC, Zuliani, C, Hutter, C, Lohi, O, Kattamis, A, Dachowska-Kalwak, I, Nilsson, A, Gerber, NU, Langenberg, KPS, Goemans, B, Zwaan, CM, Molenaar, JJ, Jager, N, Dirksen, U, Witt, R, Pfister, SM, Jones, DTW, Kopp-Schneider, A, Witt, O, van Tilburg, CM

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Chemotherapy-Colchicine Interaction in a Child with Familial Mediterranean Fever and Hodgkin Lymphoma von Langenberg-Ververgaert, Karin P S, Laxer, Ronald M, Punnett, Angela S, Dupuis, L Lee, Finkelstein, Yaron, Abla, Oussama

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Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program 'iTHER' von Langenberg, Karin P S, Meister, Michael T, Bakhuizen, Jette J, Breunis, Willemijn, Vormoor, H Josef

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The Landscape of Pediatric Precision Oncology: Program Design, Actionable Alterations, and Clinical Trial Development von Langenberg, Karin P S, Looze, Eleonora J, Molenaar, Jan J

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The Landscape of Pediatric Precision Oncology: Program Design, Actionable Alterations, and Clinical Trial Development von Langenberg, Karin P S, Looze, Eleonora J, Molenaar, Jan J

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Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy von Wienke, Judith, Visser, Lindy L., Kholosy, Waleed M., Keller, Kaylee M., Barisa, Marta, Poon, Evon, Munnings-Tomes, Sophie, Himsworth, Courtney, Calton, Elizabeth, Rodriguez, Ana, Bernardi, Ronald, van den Ham, Femke, van Hooff, Sander R., Matser, Yvette A.H., Tas, Michelle L., Langenberg, Karin P.S., Lijnzaad, Philip, Borst, Anne L., Zappa, Elisa, Bergsma, Francisca J., Strijker, Josephine G.M., Verhoeven, Bronte M., Mei, Shenglin, Kramdi, Amira, Restuadi, Restuadi, Sanchez-Bernabeu, Alvaro, Cornel, Annelisa M., Holstege, Frank C.P., Gray, Juliet C., Tytgat, Godelieve A.M., Scheijde-Vermeulen, Marijn A., Wijnen, Marc H.W.A., Dierselhuis, Miranda P., Straathof, Karin, Behjati, Sam, Wu, Wei, Heck, Albert J.R., Koster, Jan, Nierkens, Stefan, Janoueix-Lerosey, Isabelle, de Krijger, Ronald R., Baryawno, Ninib, Chesler, Louis, Anderson, John, Caron, Hubert N., Margaritis, Thanasis, van Noesel, Max M., Molenaar, Jan J.

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Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program ‘iTHER’ von Langenberg, Karin P.S., Meister, Michael T., Bakhuizen, Jette J., Boer, Judith M., van Eijkelenburg, Natasha K.A., Hulleman, Esther, Ilan, Uri, Looze, Eleonora J., Dierselhuis, Miranda P., van der Lugt, Jasper, Breunis, Willemijn, Schild, Linda G., Ober, Kimberley, van Hooff, Sander R., Scheijde-Vermeulen, Marijn A., Hiemcke-Jiwa, Laura S., Flucke, Uta E., Kranendonk, Mariette E.G., Wesseling, Pieter, Sonneveld, Edwin, Punt, Simone, Boltjes, Arjan, van Dijk, Freerk, Verwiel, Eugene T.P., Volckmann, Richard, Hehir-Kwa, Jayne Y., Kester, Lennart A., Koudijs, Marco M.J., Waanders, Esme, Holstege, Frank C.P., Vormoor, H. Josef, Hoving, Eelco W., van Noesel, Max M., Pieters, Rob, Kool, Marcel, Stumpf, Miriam, Blattner-Johnson, Mirjam, Balasubramanian, Gnana P., Van Tilburg, Cornelis M., Jones, Barbara C., Jones, David T.W., Witt, Olaf, Pfister, Stefan M., Jongmans, Marjolijn C.J., Kuiper, Roland P., de Krijger, Ronald R., Wijnen, Marc H.W., den Boer, Monique L., Zwaan, C. Michel, Kemmeren, Patrick, Koster, Jan, Tops, Bastiaan B.J., Goemans, Bianca F., Molenaar, Jan J.

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Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy von Wienke, Judith, Visser, Lindy L, Kholosy, Waleed M, Keller, Kaylee M, Barisa, Marta, Poon, Evon, Munnings-Tomes, Sophie, Himsworth, Courtney, Calton, Elizabeth, Rodriguez, Ana, Bernardi, Ronald, van den Ham, Femke, van Hooff, Sander R, Matser, Yvette A H, Tas, Michelle L, Langenberg, Karin P S, Lijnzaad, Philip, Borst, Anne L, Zappa, Elisa, Bergsma, Francisca J, Strijker, Josephine G M, Verhoeven, Bronte M, Mei, Shenglin, Kramdi, Amira, Restuadi, Restuadi, Sanchez-Bernabeu, Alvaro, Cornel, Annelisa M, Holstege, Frank C P, Gray, Juliet C, Tytgat, Godelieve A M, Scheijde-Vermeulen, Marijn A, Wijnen, Marc H W A, Dierselhuis, Miranda P, Straathof, Karin, Behjati, Sam, Wu, Wei, Heck, Albert J R, Koster, Jan, Nierkens, Stefan, Janoueix-Lerosey, Isabelle, de Krijger, Ronald R, Baryawno, Ninib, Chesler, Louis, Anderson, John, Caron, Hubert N, Margaritis, Thanasis, van Noesel, Max M, Molenaar, Jan J

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