Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency von Blackburn, J S, Liu, S, Raiser, D M, Martinez, S A, Feng, H, Meeker, N D, Gentry, J, Neuberg, D, Look, A T, Ramaswamy, S, Bernards, A, Trede, N S, Langenau, D M

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Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish von Langenau, D M, Keefe, M D, Storer, N Y, Jette, C A, Smith, A C H, Ceol, C J, Bourque, C, Look, A T, Zon, L I

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BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals von Jette, C A, Flanagan, A M, Ryan, J, Pyati, U J, Carbonneau, S, Stewart, R A, Langenau, D M, Look, A T, Letai, A

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PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis von Garcia, E. G., Veloso, A., Oliveira, M. L., Allen, J. R., Loontiens, S., Brunson, D., Do, D., Yan, C., Morris, R., Iyer, S., Garcia, S. P., Iftimia, N., Van Loocke, W., Matthijssens, F., McCarthy, K., Barata, J. T., Speleman, F., Taghon, T., Gutierrez, A., Van Vlierberghe, P., Haas, W., Blackburn, J. S., Langenau, D. M.

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Myelopoiesis in the zebrafish, Danio rerio von Bennett, Carolyn M., Kanki, John P., Rhodes, Jennifer, Liu, Ting X., Paw, Barry H., Kieran, Mark W., Langenau, David M., Delahaye-Brown, Anne, Zon, Leonard I., Fleming, Mark D., Look, A. Thomas

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Knockdown of Zebrafish Fancd2 Causes Developmental Abnormalities via p53-Dependent Apoptosis von Liu, Ting Xi, Howlett, Niall G., Deng, Min, Langenau, David M., Hsu, Karl, Rhodes, Jennifer, Kanki, John P., D'Andrea, Alan D., Look, A.Thomas

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Rhabdomyosarcoma: current challenges and their implications for developing therapies von Hettmer, Simone, Li, Zhizhong, Billin, Andrew N, Barr, Frederic G, Cornelison, D D W, Ehrlich, Alan R, Guttridge, Denis C, Hayes-Jordan, Andrea, Helman, Lee J, Houghton, Peter J, Khan, Javed, Langenau, David M, Linardic, Corinne M, Pal, Ranadip, Partridge, Terence A, Pavlath, Grace K, Rota, Rossella, Schäfer, Beat W, Shipley, Janet, Stillman, Bruce, Wexler, Leonard H, Wagers, Amy J, Keller, Charles

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The zebrafish: a new model of T-cell and thymic development von Zon, Leonard I, Langenau, David M

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Cre/Lox-Regulated Transgenic Zebrafish Model with Conditional Myc-Induced T Cell Acute Lymphoblastic Leukemia von Langenau, David M., Feng, Hui, Berghmans, Stephane, Kanki, John P., Kutok, Jeffery L., Look, A. Thomas, Cooper, Max D.

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Cloning and characterization of prostaglandin endoperoxide synthase-1 and -2 from the brook trout ovary von Roberts, Steven B, Langenau, David M, Goetz, Frederick W

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Molecular cloning and developmental expression of Tlx ( Hox11) genes in zebrafish ( Danio rerio) von Langenau, D.M, Palomero, T, Kanki, J.P, Ferrando, A.A, Zhou, Y, Zon, L.I, Look, A.T

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Zebrafish as a Model for Cancer Self-Renewal von Ignatius, Myron S., Langenau, David M.

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Use of cellular context to determine sarcoma phenotype in a new mouse sarcoma model von Hettmer, S., Liu, J., Miller, C. M., Bronson, R. T., Langenau, D. M., Wagers, A. J.

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Suppression of apoptosis by bcl-2 overexpression in lymphoid cells of transgenic zebrafish von Langenau, David M., Jette, Cicely, Berghmans, Stephane, Palomero, Teresa, Kanki, John P., Kutok, Jeffery L., Look, A.Thomas

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Clusters of circulating tumor cells traverse capillary-sized vessels von Au, SH, Storey, BD, Moore, JC, Tang, Q, Chen, Y, Javaid, S, Sarioglu, AF, Sullivan, R, Madden, MW, O’Keefe, R, Haber, DA, Maheswaran, S, Langenau, DM, Stott, SL, Toner, M

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TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia von Lobbardi, R, Pinder, J, Martinez-Pastor, B, Theodorou, M, Blackburn, JS, Abraham, BJ, Namiki, Y, Mansour, M, Abdelfattah, NS, Molodtsov, A, Alexe, G, Toiber, D, de Waard, M, Jain, E, Boukhali, M, Lion, M, Bhere, D, Shah, K, Gutierrez, A, Stegmaier, K, Silverman, LB, Sadreyev, RI, Asara, JM, Oettinger, MA, Haas, W, Look, AT, Young, RA, Mostoslavsky, R, Dellaire, G, Langenau, DM

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Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs) von Moore, Finola E, Reyon, Deepak, Sander, Jeffry D, Martinez, Sarah A, Blackburn, Jessica S, Khayter, Cyd, Ramirez, Cherie L, Joung, J Keith, Langenau, David M

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Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish von Yan, Chuan, Brunson, Dalton C., Tang, Qin, Do, Daniel, Iftimia, Nicolae A., Moore, John C., Hayes, Madeline N., Welker, Alessandra M., Garcia, Elaine G., Dubash, Taronish D., Hong, Xin, Drapkin, Benjamin J., Myers, David T., Phat, Sarah, Volorio, Angela, Marvin, Dieuwke L., Ligorio, Matteo, Dershowitz, Lyle, McCarthy, Karin M., Karabacak, Murat N., Fletcher, Jonathan A., Sgroi, Dennis C., Iafrate, John A., Maheswaran, Shyamala, Dyson, Nick J., Haber, Daniel A., Rawls, John F., Langenau, David M.

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Effects of RAS on the genesis of embryonal rhabdomyosarcoma von Langenau, David M, Keefe, Matthew D, Storer, Narie Y, Guyon, Jeffrey R, Kutok, Jeffery L, Le, Xiuning, Goessling, Wolfram, Neuberg, Donna S, Kunkel, Louis M, Zon, Leonard I

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The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma von Ignatius, Myron S., Hayes, Madeline N., Lobbardi, Riadh, Chen, Eleanor Y., McCarthy, Karin M., Sreenivas, Prethish, Motala, Zainab, Durbin, Adam D., Molodtsov, Aleksey, Reeder, Sophia, Jin, Alexander, Sindiri, Sivasish, Beleyea, Brian C., Bhere, Deepak, Alexander, Matthew S., Shah, Khalid, Keller, Charles, Linardic, Corinne M., Nielsen, Petur G., Malkin, David, Khan, Javed, Langenau, David M.

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