Mechanistic Study on the Use of the l‑Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the Development of Prodr... von Puris, Elena, Gynther, Mikko, de Lange, Elizabeth C.M, Auriola, Seppo, Hammarlund-Udenaes, Margareta, Huttunen, Kristiina M, Loryan, Irena

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Fabrication of height-modulated carbon nanotube forests: Morphologies and prospects for broadband absorption von Lange, C.M., Shen, T.-C.

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Macrophage-derived extracellular vesicles mediate a long-lasting innate immune response against hepatitis C virus von Cai, C, Koch, B, Akhras, S, Hildt, E, Zeuzem, S, Lange, C.M

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Identification of glycogen synthase kinase 3 beta as a novel host factor of hepatitis C virus replication von Saleh, M, Rüschenbaum, S, Welsch, C, Zeuzem, S, Moradpour, D, Gouttenoire, J, Lange, C.M

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Mycobacterium xenopi clinical relevance and determinants, the Netherlands von van Ingen, Jakko, Boeree, Martin J, de Lange, Wiel C M, Hoefsloot, Wouter, Bendien, Saar A, Magis-Escurra, Cecile, Dekhuijzen, Richard, van Soolingen, Dick

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The emerging role of Enterococcus spp. and multidrug-resistant bacteria causing pyogenic liver abscesses von Mücke, M.M, Kessel, J, Mücke, V.T, Sosnowsky, K, Hogardt, M, Stephan, C, Zeuzem, S, Kempf, V.A.J, Lange, C.M

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In vivo Target Residence Time and Kinetic Selectivity: The Association Rate Constant as Determinant von de Witte, Wilhelmus E.A, Danhof, Meindert, van der Graaf, Piet H, de Lange, Elizabeth C.M

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Altered protein expression of membrane transporters in isolated cerebral microvessels and brain cortex of a rat Alzheimer's disease model von Puris, Elena, Auriola, Seppo, Petralla, Sabrina, Hartman, Robin, Gynther, Mikko, de Lange, Elizabeth C.M., Fricker, Gert

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P732 PREDICTIVE VALUE OF THE INTERFERON-LAMBDA 4 GENE (IFN-L4) FOR DIRECT-/ANTIVIRAL TREATMENT IN HEPATITIS C VIRUS INFECTED PATIENTS WITH GENOTYPES 1, 2, 3, AND 4 von Susser, S, Lange, C.M, Hamdi, N, Berg, T, Perner, D, Zeuzem, S, Sarrazin, C

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Blood‐Based Biomarkers of Quinpirole Pharmacology: Cluster‐Based PK/PD and Metabolomics to Unravel the Underlying Dynamics in Rat Plasma and Brain von Brink, Willem J., Hartman, Robin, Berg, Dirk‐Jan, Flik, Gunnar, Gonzalez‐Amoros, Belén, Koopman, Nanda, Elassais‐Schaap, Jeroen, Graaf, Piet Hein, Hankemeier, Thomas, Lange, Elizabeth C.M.

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The 3D Brain Unit Network Model to Study Spatial Brain Drug Exposure under Healthy and Pathological Conditions von Vendel, Esmée, Rottschäfer, Vivi, de Lange, Elizabeth C.M.

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P0721 : Viral and host parameters in association with outcome of acute hepatitis C in HIV-coinfected patients von Dietz, J, Lutz, T, Knecht, G, Gute, P, Berkowski, C, Lange, C.M, Khaykin, P, Stephan, C, Brodt, H.-R, Zeuzem, S, Sarrazin, C

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Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research von Danhof, Meindert, de Lange, Elizabeth C.M, Della Pasqua, Oscar E, Ploeger, Bart A, Voskuyl, Rob A

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Utility of Animal Models to Understand Human Alzheimer's Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals von Qin, Tian, Prins, Samantha, Groeneveld, Geert Jan, Van Westen, Gerard, de Vries, Helga E., Wong, Yin Cheong, Bischoff, Luc J. M., de Lange, Elizabeth C. M.

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123 A FUNCTIONAL LINK BETWEEN VITAMIN D RECEPTOR AND JAK-STAT SIGNALING RESULTS IN SYNERGISTIC HEPATOCELLULAR RESPONSE TO CALCITRIOL AND INTERFERON-α von Lange, C.M, Gouttenoire, J, Duong, F.H.T, Morikawa, K, Heim, M.H, Moradpour, D

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P1309 HCV MUTANTS RESISTANT TO MACROCYCLIC NS3-4A PROTEASE INHIBITORS SUPPRESS INTERFERON-β INDUCTION BY EFFICIENT MAVS CLEAVAGE von Welsch, C, Haselow, K, Gouttenoire, J, Schneider, M, Morikawa, K, Martinez, Y, Susser, S, Sarrazin, C, Zeuzem, S, Antes, I, Moradpour, D, Lange, C.M

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Effects of daily L-dopa administration on learning and brain structure in older adults undergoing cognitive training: a randomised clinical trial von Lebedev, Alexander V., Nilsson, Jonna, Lindström, Joanna, Fredborg, William, Akenine, Ulrika, Hillilä, Carolina, Andersen, Pia, Spulber, Gabriela, de Lange, Elizabeth C. M., van den Berg, Dirk-Jan, Kivipelto, Miia, Lövdén, Martin

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LUF7244, an allosteric modulator/activator of Kv11.1 channels, counteracts dofetilide‐induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model von Qile, Muge, Beekman, Henriette D.M., Sprenkeler, David J., Houtman, Marien J.C., Ham, Willem B., Stary‐Weinzinger, Anna, Beyl, Stanislav, Hering, Steffen, Berg, Dirk‐Jan, Lange, Elizabeth C.M., Heitman, Laura H., IJzerman, Ad P., Vos, Marc A., Heyden, Marcel A.G.

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High-performance liquid chromatography of nalbuphine, butorphanol and morphine in blood and brain microdialysate samples: Application to pharmacokinetic/pharmacodynamic studies in... von Groenendaal, Dorien, Blom-Roosemalen, Margret C.M., Danhof, Meindert, Lange, Elizabeth C.M. de

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1412 COMPARATIVE GENETIC ANALYSES POINT TO HCP5 AS SUSCEPTIBILITY LOCUS FOR HCV-ASSOCIATED HEPATOCELLULAR CARCINOMA von Lange, C.M, Bibert, S, Dufour, J.-F, Cellerai, C, Cerny, A, Heim, M.H, Kaiser, L, Malinverni, R, Müllhaupt, B, Negro, F, Semela, D, Moradpour, D, Kutalik, Z, Bochud, P.-Y

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