Differential effects of social isolation in adolescent and adult mice on behavior and cortical gene expression von Lander, Sharon S., Linder-Shacham, Donna, Gaisler-Salomon, Inna

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Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex von Mitchell, Amanda C., Javidfar, Behnam, Bicks, Lucy K., Neve, Rachael, Garbett, Krassimira, Lander, Sharon S., Mirnics, Karoly, Morishita, Hirofumi, Wood, Marcelo A., Jiang, Yan, Gaisler-Salomon, Inna, Akbarian, Schahram

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Glutamate Dehydrogenase–Deficient Mice Display Schizophrenia-Like Behavioral Abnormalities and CA1-Specific Hippocampal Dysfunction von Lander, Sharon S, Khan, Usman, Lewandowski, Nicole, Chakraborty, Darpan, Provenzano, Frank A, Mingote, Susana, Chornyy, Sergiy, Frigerio, Francesca, Maechler, Pierre, Kaphzan, Hanoch, Small, Scott A, Rayport, Stephen, Gaisler-Salomon, Inna

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21.3 NEURONAL-ASTROCYTIC REGULATION OF GLUTAMATE HOMEOSTASIS: RELEVANCE TO COGNITIVE DYSFUNCTION IN SCHIZOPHRENIA von Gaisler-Salomon, Inna, Lander, Sharon S, Chakraborty, Darpan, Asraf, Kfir, Safory, Hazem, Wolosker, Herman, Kaphzan, Hanoch

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T220. THE GLUTAMINASE INHIBITOR EBSELEN PREVENTS AMPHETAMINE SENSITIZATION IN MICE von Heffetz-Giterman, Lior, Lander, Sharon S, Cohen, Reut, Gross, Amit, Gaisler-Salomon, Inna

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216. Glutamate Dehydrogenase-Deficient Mice: A Novel Mouse Model of Schizophrenia-Like Phenotypes von Lander, Sharon S, Chakraborti, Darpan, Donner, Reut, Provenzano, Frank, Lewandowski, Nicole, Mingote, Susana M, Maechler, Pierre, Rayport, Stephen, Small, Scott A, Kaphzan, Hanoch, Gaisler-Salomon, Inna

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RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin Sites von Engreitz, Jesse M., Sirokman, Klara, McDonel, Patrick, Shishkin, Alexander A., Surka, Christine, Russell, Pamela, Grossman, Sharon R., Chow, Amy Y., Guttman, Mitchell, Lander, Eric S.

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Adopt a moratorium on heritable genome editing von Lander, Eric S., Baylis, Françoise, Zhang, Feng, Charpentier, Emmanuelle, Berg, Paul, Bourgain, Catherine, Friedrich, Bärbel, Joung, J. Keith, Li, Jinsong, Liu, David, Naldini, Luigi, Nie, Jing-Bao, Qiu, Renzong, Schoene-Seifert, Bettina, Shao, Feng, Terry, Sharon, Wei, Wensheng, Winnacker, Ernst-Ludwig

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Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations von Fulco, Charles P., Nasser, Joseph, Jones, Thouis R., Munson, Glen, Bergman, Drew T., Subramanian, Vidya, Grossman, Sharon R., Anyoha, Rockwell, Doughty, Benjamin R., Patwardhan, Tejal A., Nguyen, Tung H., Kane, Michael, Perez, Elizabeth M., Durand, Neva C., Lareau, Caleb A., Stamenova, Elena K., Aiden, Erez Lieberman, Lander, Eric S., Engreitz, Jesse M.

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Detecting Novel Associations in Large Data Sets von Reshef, David N., Reshef, Yakir A., Finucane, Hilary K., Grossman, Sharon R., McVean, Gilean, Turnbaugh, Peter J., Lander, Eric S., Mitzenmacher, Michael, Sabeti, Pardis C.

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Identifying Recent Adaptations in Large-Scale Genomic Data von Grossman, Sharon R., Andersen, Kristian G., Shlyakhter, Ilya, Tabrizi, Shervin, Winnicki, Sarah, Yen, Angela, Park, Daniel J., Griesemer, Dustin, Karlsson, Elinor K., Wong, Sunny H., Cabili, Moran, Adegbola, Richard A., Bamezai, Rameshwar N.K., Hill, Adrian V.S., Vannberg, Fredrik O., Rinn, John L., Lander, Eric S., Schaffner, Stephen F., Sabeti, Pardis C.

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Systematic dissection of genomic features determining transcription factor binding and enhancer function von Grossman, Sharon R., Zhang, Xiaolan, Wang, Li, Engreitz, Jesse, Melnikov, Alexandre, Rogov, Peter, Tewhey, Ryan, Isakova, Alina, Deplancke, Bart, Bernstein, Bradley E., Mikkelsen, Tarjei S., Lander, Eric S.

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Systematic mapping of functional enhancer-promoter connections with CRISPR interference von Fulco, Charles P., Munschauer, Mathias, Anyoha, Rockwell, Munson, Glen, Grossman, Sharon R., Perez, Elizabeth M., Kane, Michael, Cleary, Brian, Lander, Eric S., Engreitz, Jesse M.

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Discovery and characterization of artifactual mutations in deep coverage targeted capture sequencing data due to oxidative DNA damage during sample preparation von Costello, Maura, Pugh, Trevor J, Fennell, Timothy J, Stewart, Chip, Lichtenstein, Lee, Meldrim, James C, Fostel, Jennifer L, Friedrich, Dennis C, Perrin, Danielle, Dionne, Danielle, Kim, Sharon, Gabriel, Stacey B, Lander, Eric S, Fisher, Sheila, Getz, Gad

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Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection von Grossman, Sharon R, Shylakhter, Ilya, Karlsson, Elinor K, Byrne, Elizabeth H, Morales, Shannon, Frieden, Gabriel, Hostetter, Elizabeth, Angelino, Elaine, Garber, Manuel, Zuk, Or, Lander, Eric S, Schaffner, Stephen F, Sabeti, Pardis C

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Compatibility rules of human enhancer and promoter sequences von Bergman, Drew T., Jones, Thouis R., Liu, Vincent, Ray, Judhajeet, Jagoda, Evelyn, Siraj, Layla, Kang, Helen Y., Nasser, Joseph, Kane, Michael, Rios, Antonio, Nguyen, Tung H., Grossman, Sharon R., Fulco, Charles P., Lander, Eric S., Engreitz, Jesse M.

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Positional specificity of different transcription factor classes within enhancers von Grossman, Sharon R., Engreitz, Jesse, Ray, John P., Nguyen, Tung H., Hacohen, Nir, Lander, Eric S.

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The genetic landscape of high-risk neuroblastoma von Pugh, Trevor J, Morozova, Olena, Attiyeh, Edward F, Asgharzadeh, Shahab, Wei, Jun S, Auclair, Daniel, Carter, Scott L, Cibulskis, Kristian, Hanna, Megan, Kiezun, Adam, Kim, Jaegil, Lawrence, Michael S, Lichenstein, Lee, McKenna, Aaron, Pedamallu, Chandra Sekhar, Ramos, Alex H, Shefler, Erica, Sivachenko, Andrey, Sougnez, Carrie, Stewart, Chip, Ally, Adrian, Birol, Inanc, Chiu, Readman, Corbett, Richard D, Hirst, Martin, Jackman, Shaun D, Kamoh, Baljit, Khodabakshi, Alireza Hadj, Krzywinski, Martin, Lo, Allan, Moore, Richard A, Mungall, Karen L, Qian, Jenny, Tam, Angela, Thiessen, Nina, Zhao, Yongjun, Cole, Kristina A, Diamond, Maura, Diskin, Sharon J, Mosse, Yael P, Wood, Andrew C, Ji, Lingyun, Sposto, Richard, Badgett, Thomas, London, Wendy B, Moyer, Yvonne, Gastier-Foster, Julie M, Smith, Malcolm A, Auvil, Jaime M Guidry, Gerhard, Daniela S, Hogarty, Michael D, Jones, Steven J M, Lander, Eric S, Gabriel, Stacey B, Getz, Gad, Seeger, Robert C, Khan, Javed, Marra, Marco A, Meyerson, Matthew, Maris, John M

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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction von Do, Ron, Stitziel, Nathan O., Won, Hong-Hee, Jørgensen, Anders Berg, Duga, Stefano, Angelica Merlini, Pier, Kiezun, Adam, Farrall, Martin, Goel, Anuj, Zuk, Or, Guella, Illaria, Asselta, Rosanna, Lange, Leslie A., Peloso, Gina M., Auer, Paul L., Girelli, Domenico, Martinelli, Nicola, Farlow, Deborah N., DePristo, Mark A., Roberts, Robert, Stewart, Alexander F. R., Saleheen, Danish, Danesh, John, Epstein, Stephen E., Sivapalaratnam, Suthesh, Kees Hovingh, G., Kastelein, John J., Samani, Nilesh J., Schunkert, Heribert, Erdmann, Jeanette, Shah, Svati H., Kraus, William E., Davies, Robert, Nikpay, Majid, Johansen, Christopher T., Wang, Jian, Hegele, Robert A., Hechter, Eliana, Marz, Winfried, Kleber, Marcus E., Huang, Jie, Johnson, Andrew D., Li, Mingyao, Burke, Greg L., Gross, Myron, Liu, Yongmei, Assimes, Themistocles L., Heiss, Gerardo, Lange, Ethan M., Folsom, Aaron R., Taylor, Herman A., Olivieri, Oliviero, Hamsten, Anders, Clarke, Robert, Reilly, Dermot F., Yin, Wu, Rivas, Manuel A., Donnelly, Peter, Rossouw, Jacques E., Psaty, Bruce M., Herrington, David M., Wilson, James G., Rich, Stephen S., Bamshad, Michael J., Tracy, Russell P., Adrienne Cupples, L., Rader, Daniel J., Reilly, Muredach P., Spertus, John A., Cresci, Sharon, Hartiala, Jaana, Wilson Tang, W. H., Hazen, Stanley L., Allayee, Hooman, Reiner, Alex P., Carlson, Christopher S., Kooperberg, Charles, Jackson, Rebecca D., Boerwinkle, Eric, Lander, Eric S., Schwartz, Stephen M., Siscovick, David S., McPherson, Ruth, Tybjaerg-Hansen, Anne, Abecasis, Goncalo R., Watkins, Hugh, Nickerson, Deborah A., Ardissino, Diego, Sunyaev, Shamil R., O'Donnell, Christopher J., Altshuler, David, Gabriel, Stacey, Kathiresan, Sekar

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Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory von Lander, Sharon Sima, Chornyy, Sergiy, Safory, Hazem, Gross, Amit, Wolosker, Herman, Gaisler‐Salomon, Inna

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