Impact of Organism Identification Method on Central Line-Associated Bloodstream Infection Designation von Gomez, Emily J, Roberts, Amity L, Robinson, Diana P, Alby, Kevin, Ledeboer, Nathan A, Doern, Christopher D, Lander, David W, Bearman, Gonzalo, Sullivan, Kaede V

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Identification and characterization of essential genes in the human genome von Wang, Tim, Birsoy, Kivanç, Hughes, Nicholas W., Krupczak, Kevin M., Post, Yorick, Wei, Jenny J., Lander, Eric S., Sabatini, David M.

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Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras von Wang, Tim, Yu, Haiyan, Hughes, Nicholas W., Liu, Bingxu, Kendirli, Arek, Klein, Klara, Chen, Walter W., Lander, Eric S., Sabatini, David M.

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lincRNAs act in the circuitry controlling pluripotency and differentiation von Guttman, Mitchell, Donaghey, Julie, Carey, Bryce W., Garber, Manuel, Grenier, Jennifer K., Munson, Glen, Young, Geneva, Lucas, Anne Bergstrom, Ach, Robert, Bruhn, Laurakay, Yang, Xiaoping, Amit, Ido, Meissner, Alexander, Regev, Aviv, Rinn, John L., Root, David E., Lander, Eric S.

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Punctuated Evolution of Prostate Cancer Genomes von Baca, Sylvan C., Prandi, Davide, Lawrence, Michael S., Mosquera, Juan Miguel, Romanel, Alessandro, Drier, Yotam, Park, Kyung, Kitabayashi, Naoki, MacDonald, Theresa Y., Ghandi, Mahmoud, Van Allen, Eliezer, Kryukov, Gregory V., Sboner, Andrea, Theurillat, Jean-Philippe, Soong, T. David, Nickerson, Elizabeth, Auclair, Daniel, Tewari, Ashutosh, Beltran, Himisha, Onofrio, Robert C., Boysen, Gunther, Guiducci, Candace, Barbieri, Christopher E., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Saksena, Gordon, Voet, Douglas, Ramos, Alex H., Winckler, Wendy, Cipicchio, Michelle, Ardlie, Kristin, Kantoff, Philip W., Berger, Michael F., Gabriel, Stacey B., Golub, Todd R., Meyerson, Matthew, Lander, Eric S., Elemento, Olivier, Getz, Gad, Demichelis, Francesca, Rubin, Mark A., Garraway, Levi A.

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Absolute quantification of somatic DNA alterations in human cancer von Carter, Scott L, Cibulskis, Kristian, Helman, Elena, McKenna, Aaron, Shen, Hui, Zack, Travis, Laird, Peter W, Onofrio, Robert C, Winckler, Wendy, Weir, Barbara A, Beroukhim, Rameen, Pellman, David, Levine, Douglas A, Lander, Eric S, Meyerson, Matthew, Getz, Gad

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Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine von Van Allen, Eliezer M, Wagle, Nikhil, Stojanov, Petar, Perrin, Danielle L, Cibulskis, Kristian, Marlow, Sara, Jane-Valbuena, Judit, Friedrich, Dennis C, Kryukov, Gregory, Carter, Scott L, McKenna, Aaron, Sivachenko, Andrey, Rosenberg, Mara, Kiezun, Adam, Voet, Douglas, Lawrence, Michael, Lichtenstein, Lee T, Gentry, Jeff G, Huang, Franklin W, Fostel, Jennifer, Farlow, Deborah, Barbie, David, Gandhi, Leena, Lander, Eric S, Gray, Stacy W, Joffe, Steven, Janne, Pasi, Garber, Judy, MacConaill, Laura, Lindeman, Neal, Rollins, Barrett, Kantoff, Philip, Fisher, Sheila A, Gabriel, Stacey, Getz, Gad, Garraway, Levi A

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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals von Kellis, Manolis, Feldser, David, Cassady, John P, Amit, Ido, Lander, Eric S, Zuk, Or, Lin, Michael F, Carey, Bryce W, Garber, Manuel, Mikkelsen, Tarjei S, Jacks, Tyler, Hacohen, Nir, Guttman, Mitchell, French, Courtney, Cabili, Moran N, Huarte, Maite, Regev, Aviv, Rinn, John L, Jaenisch, Rudolf, Bernstein, Bradley E

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A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen von Moffat, Jason, Grueneberg, Dorre A., Yang, Xiaoping, Kim, So Young, Kloepfer, Angela M., Hinkle, Gregory, Piqani, Bruno, Eisenhaure, Thomas M., Luo, Biao, Grenier, Jennifer K., Carpenter, Anne E., Foo, Shi Yin, Stewart, Sheila A., Stockwell, Brent R., Hacohen, Nir, Hahn, William C., Lander, Eric S., Sabatini, David M., Root, David E.

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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction von Do, Ron, Stitziel, Nathan O., Won, Hong-Hee, Jørgensen, Anders Berg, Duga, Stefano, Angelica Merlini, Pier, Kiezun, Adam, Farrall, Martin, Goel, Anuj, Zuk, Or, Guella, Illaria, Asselta, Rosanna, Lange, Leslie A., Peloso, Gina M., Auer, Paul L., Girelli, Domenico, Martinelli, Nicola, Farlow, Deborah N., DePristo, Mark A., Roberts, Robert, Stewart, Alexander F. R., Saleheen, Danish, Danesh, John, Epstein, Stephen E., Sivapalaratnam, Suthesh, Kees Hovingh, G., Kastelein, John J., Samani, Nilesh J., Schunkert, Heribert, Erdmann, Jeanette, Shah, Svati H., Kraus, William E., Davies, Robert, Nikpay, Majid, Johansen, Christopher T., Wang, Jian, Hegele, Robert A., Hechter, Eliana, Marz, Winfried, Kleber, Marcus E., Huang, Jie, Johnson, Andrew D., Li, Mingyao, Burke, Greg L., Gross, Myron, Liu, Yongmei, Assimes, Themistocles L., Heiss, Gerardo, Lange, Ethan M., Folsom, Aaron R., Taylor, Herman A., Olivieri, Oliviero, Hamsten, Anders, Clarke, Robert, Reilly, Dermot F., Yin, Wu, Rivas, Manuel A., Donnelly, Peter, Rossouw, Jacques E., Psaty, Bruce M., Herrington, David M., Wilson, James G., Rich, Stephen S., Bamshad, Michael J., Tracy, Russell P., Adrienne Cupples, L., Rader, Daniel J., Reilly, Muredach P., Spertus, John A., Cresci, Sharon, Hartiala, Jaana, Wilson Tang, W. H., Hazen, Stanley L., Allayee, Hooman, Reiner, Alex P., Carlson, Christopher S., Kooperberg, Charles, Jackson, Rebecca D., Boerwinkle, Eric, Lander, Eric S., Schwartz, Stephen M., Siscovick, David S., McPherson, Ruth, Tybjaerg-Hansen, Anne, Abecasis, Goncalo R., Watkins, Hugh, Nickerson, Deborah A., Ardissino, Diego, Sunyaev, Shamil R., O'Donnell, Christopher J., Altshuler, David, Gabriel, Stacey, Kathiresan, Sekar

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Transcriptional regulatory code of a eukaryotic genome von Harbison, C.T, Gordon, D.B, Lee, T.I, Rinaldi, N.J, Macisaac, K.D, Danford, T.W, Hannett, N.M, Tagne, J.B, Reynolds, D.B, Yoo, J

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Assessing the impact of population stratification on genetic association studies von Reich, David, Freedman, Matthew L, Penney, Kathryn L, McDonald, Gavin J, Mignault, Andre A, Patterson, Nick, Gabriel, Stacey B, Topol, Eric J, Smoller, Jordan W, Pato, Carlos N, Pato, Michele T, Petryshen, Tracey L, Kolonel, Laurence N, Lander, Eric S, Sklar, Pamela, Henderson, Brian, Hirschhorn, Joel N, Altshuler, David

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The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease von Lamb, Justin, Crawford, Emily D., Peck, David, Modell, Joshua W., Blat, Irene C., Wrobel, Matthew J., Lerner, Jim, Brunet, Jean-Philippe, Subramanian, Aravind, Ross, Kenneth N., Reich, Michael, Hieronymus, Haley, Wei, Guo, Armstrong, Scott A., Haggarty, Stephen J., Clemons, Paul A., Wei, Ru, Carr, Steven A., Lander, Eric S., Golub, Todd R.

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Thermal Energy Transport in Oxide Nuclear Fuel von Hurley, David H, El-Azab, Anter, Bryan, Matthew S, Cooper, Michael W. D, Dennett, Cody A, Gofryk, Krzysztof, He, Lingfeng, Khafizov, Marat, Lander, Gerard H, Manley, Michael E, Mann, J. Matthew, Marianetti, Chris A, Rickert, Karl, Selim, Farida A, Tonks, Michael R, Wharry, Janelle P

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Mutational heterogeneity in cancer and the search for new cancer-associated genes von Lawrence, Michael S., Stojanov, Petar, Polak, Paz, Kryukov, Gregory V., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Stewart, Chip, Mermel, Craig H., Roberts, Steven A., Kiezun, Adam, Hammerman, Peter S., McKenna, Aaron, Drier, Yotam, Zou, Lihua, Ramos, Alex H., Pugh, Trevor J., Stransky, Nicolas, Helman, Elena, Kim, Jaegil, Sougnez, Carrie, Ambrogio, Lauren, Nickerson, Elizabeth, Shefler, Erica, Cortés, Maria L., Auclair, Daniel, Saksena, Gordon, Voet, Douglas, Noble, Michael, DiCara, Daniel, Lin, Pei, Lichtenstein, Lee, Heiman, David I., Fennell, Timothy, Imielinski, Marcin, Hernandez, Bryan, Hodis, Eran, Baca, Sylvan, Dulak, Austin M., Lohr, Jens, Landau, Dan-Avi, Wu, Catherine J., Melendez-Zajgla, Jorge, Hidalgo-Miranda, Alfredo, Koren, Amnon, McCarroll, Steven A., Mora, Jaume, Lee, Ryan S., Crompton, Brian, Onofrio, Robert, Parkin, Melissa, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Roberts, Charles W. M., Biegel, Jaclyn A., Stegmaier, Kimberly, Bass, Adam J., Garraway, Levi A., Meyerson, Matthew, Golub, Todd R., Gordenin, Dmitry A., Sunyaev, Shamil, Lander, Eric S., Getz, Gad

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A comparative genomics multitool for scientific discovery and conservation von Genereux, Diane P, Serres, Aitor, Armstrong, Joel, Johnson, Jeremy, Marinescu, Voichita D, Murén, Eva, Juan, David

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A high-resolution map of human evolutionary constraint using 29 mammals von Lindblad-Toh, Kerstin, Garber, Manuel, Zuk, Or, Lin, Michael F., Parker, Brian J., Washietl, Stefan, Kheradpour, Pouya, Ernst, Jason, Jordan, Gregory, Mauceli, Evan, Ward, Lucas D., Lowe, Craig B., Holloway, Alisha K., Clamp, Michele, Gnerre, Sante, Alföldi, Jessica, Beal, Kathryn, Chang, Jean, Clawson, Hiram, Cuff, James, Di Palma, Federica, Fitzgerald, Stephen, Flicek, Paul, Guttman, Mitchell, Hubisz, Melissa J., Jaffe, David B., Jungreis, Irwin, Kent, W. James, Kostka, Dennis, Lara, Marcia, Martins, Andre L., Massingham, Tim, Moltke, Ida, Raney, Brian J., Rasmussen, Matthew D., Robinson, Jim, Stark, Alexander, Vilella, Albert J., Wen, Jiayu, Xie, Xiaohui, Zody, Michael C., Worley, Kim C., Kovar, Christie L., Muzny, Donna M., Gibbs, Richard A., Warren, Wesley C., Mardis, Elaine R., Weinstock, George M., Wilson, Richard K., Birney, Ewan, Margulies, Elliott H., Herrero, Javier, Green, Eric D., Haussler, David, Siepel, Adam, Goldman, Nick, Pollard, Katherine S., Pedersen, Jakob S., Lander, Eric S., Kellis, Manolis

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Massively parallel base editing to map variant effects in human hematopoiesis von Martin-Rufino, Jorge D., Castano, Nicole, Pang, Michael, Grody, Emanuelle I., Joubran, Samantha, Caulier, Alexis, Wahlster, Lara, Li, Tongqing, Qiu, Xiaojie, Riera-Escandell, Anna Maria, Newby, Gregory A., Al’Khafaji, Aziz, Chaudhary, Santosh, Black, Susan, Weng, Chen, Munson, Glen, Liu, David R., Wlodarski, Marcin W., Sims, Kacie, Oakley, Jamie H., Fasano, Ross M., Xavier, Ramnik J., Lander, Eric S., Klein, Daryl E., Sankaran, Vijay G.

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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma von Perry, Jennifer A, Kiezun, Adam, Tonzi, Peter, Van Allen, Eliezer M, Carter, Scott L, Baca, Sylvan C, Cowley, Glenn S, Bhatt, Ami S, Rheinbay, Esther, Pedamallu, Chandra Sekhar, Helman, Elena, Taylor-Weiner, Amaro, McKenna, Aaron, DeLuca, David S, Lawrence, Michael S, Ambrogio, Lauren, Sougnez, Carrie, Sivachenko, Andrey, Walensky, Loren D, Wagle, Nikhil, Mora, Jaume, de Torres, Carmen, Lavarino, Cinzia, Dos Santos Aguiar, Simone, Yunes, Jose Andres, Brandalise, Silvia Regina, Mercado-Celis, Gabriela Elisa, Melendez-Zajgla, Jorge, Cárdenas-Cardós, Rocío, Velasco-Hidalgo, Liliana, Roberts, Charles W M, Garraway, Levi A, Rodriguez-Galindo, Carlos, Gabriel, Stacey B, Lander, Eric S, Golub, Todd R, Orkin, Stuart H, Getz, Gad, Janeway, Katherine A

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Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication von Carneiro, Miguel, Rubin, Carl-Johan, Di Palma, Federica, Albert, Frank W., Alföldi, Jessica, Barrio, Alvaro Martinez, Pielberg, Gerli, Rafati, Nima, Sayyab, Shumaila, Turner-Maier, Jason, Younis, Shady, Afonso, Sandra, Aken, Bronwen, Alves, Joel M., Barrell, Daniel, Bolet, Gerard, Boucher, Samuel, Burbano, Hernán A., Campos, Rita, Chang, Jean L., Duranthon, Veronique, Fontanesi, Luca, Garreau, Hervé, Heiman, David, Johnson, Jeremy, Mage, Rose G., Peng, Ze, Queney, Guillaume, Rogel-Gaillard, Claire, Ruffier, Magali, Searle, Steve, Villafuerte, Rafael, Xiong, Anqi, Young, Sarah, Forsberg-Nilsson, Karin, Good, Jeffrey M., Lander, Eric S., Ferrand, Nuno, Lindblad-Toh, Kerstin, Andersson, Leif

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