Development of mAb-based polyglutamine-dependent and polyglutamine length-independent huntingtin quantification assays with cross-site validation von Fischer, David F, Dijkstra, Sipke, Lo, Kimberly, Suijker, Johnny, Correia, Ana C P, Naud, Patricia, Poirier, Martin, Tessari, Michela A, Boogaard, Ivette, Flynn, Geraldine, Visser, Mijke, Lamers, Marieke B A C, McAllister, George, Munoz-Sanjuan, Ignacio, Macdonald, Douglas

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Quantification assays for total and polyglutamine-expanded huntingtin proteins von Macdonald, Douglas, Tessari, Michela A, Boogaard, Ivette, Smith, Melanie, Pulli, Kristiina, Szynol, Agnieszka, Albertus, Faywell, Lamers, Marieke B A C, Dijkstra, Sipke, Kordt, Daniel, Reindl, Wolfgang, Herrmann, Frank, McAllister, George, Fischer, David F, Munoz-Sanjuan, Ignacio

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[1,2,4]Triazolo[1,5‑a]pyrimidine Phosphodiesterase 2A Inhibitors: Structure and Free-Energy Perturbation-Guided Exploration von Tresadern, Gary, Velter, Ingrid, Trabanco, Andrés A, Van den Keybus, Frans, Macdonald, Gregor J, Somers, Marijke V. F, Vanhoof, Greet, Leonard, Philip M, Lamers, Marieke B. A. C, Van Roosbroeck, Yves E. M, Buijnsters, Peter J. J. A

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Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)‑5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)am... von Osborne, James D, Matthews, Thomas P, McHardy, Tatiana, Proisy, Nicolas, Cheung, Kwai-Ming J, Lainchbury, Michael, Brown, Nathan, Walton, Michael I, Eve, Paul D, Boxall, Katherine J, Hayes, Angela, Henley, Alan T, Valenti, Melanie R, De Haven Brandon, Alexis K, Box, Gary, Jamin, Yann, Robinson, Simon P, Westwood, Isaac M, van Montfort, Rob L. M, Leonard, Philip M, Lamers, Marieke B. A. C, Reader, John C, Aherne, G. Wynne, Raynaud, Florence I, Eccles, Suzanne A, Garrett, Michelle D, Collins, Ian

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Structure of human caspase-6 in complex with Z-VAD-FMK: New peptide binding mode observed for the non-canonical caspase conformation von Müller, Ilka, Lamers, Marieke B.A.C., Ritchie, Alison J., Dominguez, Celia, Munoz-Sanjuan, Ignacio, Kiselyov, Alex

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A New Apo-Caspase-6 Crystal Form Reveals the Active Conformation of the Apoenzyme von Müller, Ilka, Lamers, Marieke B.A.C., Ritchie, Alison J., Park, Hyunsun, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Maillard, Michel, Kiselyov, Alex

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Structure of a Cys25→Ser mutant of human cathepsin S von Turkenburg, Johan P., Lamers, Marieke B. A. C., Brzozowski, A. Marek, Wright, Lisa M., Hubbard, Roderick E., Sturt, Simone L., Williams, David H.

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Effectiveness of a web‐based treatment decision aid for men with lower urinary tract symptoms due to benign prostatic hyperplasia von Wijden, Fieke C., Angst, Isabel B., Lamers, Romy E.D., Cuypers, Maarten, Vries, Marieke, Melick, Harm H.E., Beij, Jeltje S., Oerlemans, Dennis J.A.J., Beek, Kees, Kil, Paul J.M.

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Treatment Preferences of Patients With Benign Prostatic Hyperplasia Before and After Using a Web-based Decision Aid von Lamers, Romy E.D., van der Wijden, Fieke C., de Angst, Isabel B., de Vries, Marieke, Cuypers, Maarten, van Melick, Harm H.E., de Beij, Jeltje S., Oerlemans, Dennis J.A.J., van de Beek, Kees, Bosch, Ruud J.L.H. R., Kil, Paul J.M.

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Predictors of biologic-free disease control in patients with rheumatoid arthritis after stopping tumor necrosis factor inhibitor treatment von Ghiti Moghadam, Marjan, Lamers-Karnebeek, Femke B G, Vonkeman, Harald E, Ten Klooster, Peter M, Tekstra, Janneke, van Schaeybroeck, Barbara, Klaasen, Ruth, van Onna, Marieke, Bernelot Moens, Hein J, Visser, Henk, Schilder, Annemarie M, Kok, Marc R, Landewé, Robert B M, van Riel, Piet L C M, van de Laar, Mart A F J, Jansen, Tim L

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Lead Optimization toward Proof-of-Concept Tools for Huntington’s Disease within a 4‑(1H‑Pyrazol-4-yl)pyrimidine Class of Pan-JNK Inhibitors von Wityak, John, McGee, Kevin F, Conlon, Michael P, Song, Ren Hua, Duffy, Bryan C, Clayton, Brent, Lynch, Michael, Wang, Gwen, Freeman, Emily, Haber, James, Kitchen, Douglas B, Manning, David D, Ismail, Jiffry, Khmelnitsky, Yuri, Michels, Peter, Webster, Jeff, Irigoyen, Macarena, Luche, Michele, Hultman, Monica, Bai, Mei, Kuok, IokTeng D, Newell, Ryan, Lamers, Marieke, Leonard, Philip, Yates, Dawn, Matthews, Kim, Ongeri, Lynette, Clifton, Steve, Mead, Tania, Deupree, Susan, Wheelan, Pat, Lyons, Kathy, Wilson, Claire, Kiselyov, Alex, Toledo-Sherman, Leticia, Beconi, Maria, Muñoz-Sanjuan, Ignacio, Bard, Jonathan, Dominguez, Celia

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Predictors of biologic-free disease control in patients with rheumatoid arthritis after stopping tumor necrosis factor inhibitor treatment von Ghiti Moghadam, Marjan, Lamers-Karnebeek, Femke B. G., Vonkeman, Harald E., ten Klooster, Peter M., Tekstra, Janneke, van Schaeybroeck, Barbara, Klaasen, Ruth, van Onna, Marieke, Bernelot Moens, Hein J., Visser, Henk, Schilder, Annemarie M., Kok, Marc R., Landewé, Robert B. M., van Riel, Piet L. C. M., van de Laar, Mart A. F. J., Jansen, Tim L.

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Effect of l-arginine on lower oesophageal sphincter motility in man von Straathof, Jan Willem A, Adamse, Marieke, Onkenhout, Willem, Lamers, Cornelis B. H. W, Masclee, Ad A. M

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Baculoviral Expression and Characterization of Rodent Cathepsin S von Mason, Clive S., Lamers, Marieke B.A.C., Henderson, Ian M.J., Monk, Tracy, Williams, David H.

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Biosynthesis of the 25-kDa protein in the macrogametes/zygotes of Plasmodium falciparum von Fries, Hella C.W., Lamers, Marieke B.A.C., van Deursen, Jan, Ponnudurai, Thivi, Meuwissen, Joseph H.E.Th

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