Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer von Färkkilä, Anniina, Gulhan, Doga C., Casado, Julia, Jacobson, Connor A., Nguyen, Huy, Kochupurakkal, Bose, Maliga, Zoltan, Yapp, Clarence, Chen, Yu-An, Schapiro, Denis, Zhou, Yinghui, Graham, Julie R., Dezube, Bruce J., Munster, Pamela, Santagata, Sandro, Garcia, Elizabeth, Rodig, Scott, Lako, Ana, Chowdhury, Dipanjan, Shapiro, Geoffrey I., Matulonis, Ursula A., Park, Peter J., Hautaniemi, Sampsa, Sorger, Peter K., Swisher, Elizabeth M., D’Andrea, Alan D., Konstantinopoulos, Panagiotis A.

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Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial von Uppaluri, Ravindra, Campbell, Katie M, Egloff, Ann Marie, Zolkind, Paul, Skidmore, Zachary L, Nussenbaum, Brian, Paniello, Randal C, Rich, Jason T, Jackson, Ryan, Pipkorn, Patrik, Michel, Loren S, Ley, Jessica, Oppelt, Peter, Dunn, Gavin P, Barnell, Erica K, Spies, Nicholas C, Lin, Tianxiang, Li, Tiantian, Mulder, David T, Hanna, Youstina, Cirlan, Iulia, Pugh, Trevor J, Mudianto, Tenny, Riley, Rachel, Zhou, Liye, Jo, Vickie Y, Stachler, Matthew D, Hanna, Glenn J, Kass, Jason, Haddad, Robert, Schoenfeld, Jonathan D, Gjini, Evisa, Lako, Ana, Thorstad, Wade, Gay, Hiram A, Daly, Mackenzie, Rodig, Scott J, Hagemann, Ian S, Kallogjeri, Dorina, Piccirillo, Jay F, Chernock, Rebecca D, Griffith, Malachi, Griffith, Obi L, Adkins, Douglas R

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Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade von Gu, Shengqing Stan, Zhang, Wubing, Wang, Xiaoqing, Jiang, Peng, Traugh, Nicole, Li, Ziyi, Meyer, Clifford, Stewig, Blair, Xie, Yingtian, Bu, Xia, Manos, Michael P, Font-Tello, Alba, Gjini, Evisa, Lako, Ana, Lim, Klothilda, Conway, Jake, Tewari, Alok K, Zeng, Zexian, Sahu, Avinash Das, Tokheim, Collin, Weirather, Jason L, Fu, Jingxin, Zhang, Yi, Kroger, Benjamin, Liang, Jin Hua, Cejas, Paloma, Freeman, Gordon J, Rodig, Scott, Long, Henry W, Gewurz, Benjamin E, Hodi, F Stephen, Brown, Myles, Liu, X Shirley

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Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity von Mahadevan, Navin R, Knelson, Erik H, Wolff, Jacquelyn O, Vajdi, Amir, Saigí, Maria, Campisi, Marco, Hong, Deli, Thai, Tran C, Piel, Brandon, Han, Saemi, Reinhold, Bruce B, Duke-Cohan, Jonathan S, Poitras, Michael J, Taus, Luke J, Lizotte, Patrick H, Portell, Andrew, Quadros, Victor, Santucci, Alison D, Murayama, Takahiko, Cañadas, Israel, Kitajima, Shunsuke, Akitsu, Aoi, Fridrikh, Maya, Watanabe, Hideo, Reardon, Brendan, Gokhale, Prafulla C, Paweletz, Cloud P, Awad, Mark M, Van Allen, Eliezer M, Lako, Ana, Wang, Xi-Tao, Chen, Benjamin, Hong, Fangxin, Sholl, Lynette M, Tolstorukov, Michael Y, Pfaff, Kathleen, Jänne, Pasi A, Gjini, Evisa, Edwards, Robin, Rodig, Scott, Reinherz, Ellis L, Oser, Matthew G, Barbie, David A

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The Society for Immunotherapy of Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation von Taube, Janis M, Akturk, Guray, Angelo, Michael, Engle, Elizabeth L, Gnjatic, Sacha, Greenbaum, Shirley, Greenwald, Noah F, Hedvat, Cyrus V, Hollmann, Travis J, Juco, Jonathan, Parra, Edwin R, Rebelatto, Marlon C, Rimm, David L, Rodriguez-Canales, Jaime, Schalper, Kurt A, Stack, Edward C, Ferreira, Cláudia S, Korski, Konstanty, Lako, Ana, Rodig, Scott J, Schenck, Emanuel, Steele, Keith E, Surace, Michael J, Tetzlaff, Michael T, von Loga, Katharina, Wistuba, Ignacio I, Bifulco, Carlo B

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Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade von Gstalder, Cécile, Liu, David, Miao, Diana, Lutterbach, Bart, DeVine, Alexander L, Lin, Chenyu, Shettigar, Megha, Pancholi, Priya, Buchbinder, Elizabeth I, Carter, Scott L, Manos, Michael P, Rojas-Rudilla, Vanesa, Brennick, Ryan, Gjini, Evisa, Chen, Pei-Hsuan, Lako, Ana, Rodig, Scott, Yoon, Charles H, Freeman, Gordon J, Barbie, David A, Hodi, F Stephen, Miles, Wayne, Van Allen, Eliezer M, Haq, Rizwan

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Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival von Wang, Yubao, Begley, Michael, Li, Qing, Huang, Hai-Tsang, Lako, Ana, Eck, Michael J., Gray, Nathanael S., Mitchison, Timothy J., Cantley, Lewis C., Zhao, Jean J.

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Angiopoietin-2 as a Biomarker and Target for Immune Checkpoint Therapy von Wu, Xinqi, Giobbie-Hurder, Anita, Liao, Xiaoyun, Connelly, Courtney, Connolly, Erin M, Li, Jingjing, Manos, Michael P, Lawrence, Donald, McDermott, David, Severgnini, Mariano, Zhou, Jun, Gjini, Evisa, Lako, Ana, Lipschitz, Mikel, Pak, Christine J, Abdelrahman, Sara, Rodig, Scott, Hodi, F Stephen

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966 Spatial profiling of the metastatic castration resistant prostate cancer tumor microenvironment at the single cell level reveals insights into intrinsic resistance to immunothe... von Lako, Ana, Fisher, Andrew, Lewin, Anne, Barrientos, Katharine, Chen, Benjamin

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FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues von Font-Tello, Alba, Kesten, Nikolas, Xie, Yingtian, Taing, Len, Varešlija, Damir, Young, Leonie S., Hamid, Anis A., Van Allen, Eliezer M., Sweeney, Christopher J., Gjini, Evisa, Lako, Ana, Hodi, F. Steven, Bellmunt, Joaquim, Brown, Myles, Cejas, Paloma, Long, Henry W.

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Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands von Garman, Bradley, Jiang, Can, Daouti, Sherif, Kumar, Sanah, Mehta, Priyanka, Jacques, Miye K., Menard, Laurence, Manjarrez-Orduno, Nataly, Dolfi, Sonia, Mukherjee, Piali, Rai, Sharmila Chamling, Lako, Ana, Koenitzer, Jennifer D., David, Justin M.

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MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells von Wang, Yubao, Lee, Young-Mi, Baitsch, Lukas, Huang, Alan, Xiang, Yi, Tong, Haoxuan, Lako, Ana, Von, Thanh, Choi, Christine, Lim, Elgene, Min, Junxia, Li, Li, Stegmeier, Frank, Schlegel, Robert, Eck, Michael J, Gray, Nathanael S, Mitchison, Timothy J, Zhao, Jean J

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624 Longitudinal scRNAseq profiling of PBMCs from melanoma patients treated with anti-CTLA4 or anti-PD1/CTLA4 combination elucidates mechanisms of immunotherapy resistance von Lako, Ana, Rai, Sharmila Chamling, Mukherjee, Piali, O’Brien, Brendan, Tenney, Daniel, Dolfi, Sonia, Bhatt, Rupal, Chen, Benjamin

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Bevacizumab improves tumor infiltration of mature dendritic cells and effector T-cells in triple-negative breast cancer patients von Boucher, Yves, Kumar, Ashwin S., Posada, Jessica M., Gjini, Evisa, Pfaff, Kathleen, Lipschitz, Mikel, Lako, Ana, Duda, Dan G., Rodig, Scott J., Hodi, F. Stephen, Jain, Rakesh K.

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Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer von Färkkilä, Anniina, Gulhan, Doga C., Casado, Julia, Jacobson, Connor A., Nguyen, Huy, Kochupurakkal, Bose, Maliga, Zoltan, Yapp, Clarence, Chen, Yu-An, Schapiro, Denis, Zhou, Yinghui, Graham, Julie R., Dezube, Bruce J., Munster, Pamela, Santagata, Sandro, Garcia, Elizabeth, Rodig, Scott, Lako, Ana, Chowdhury, Dipanjan, Shapiro, Geoffrey I., Matulonis, Ursula A., Park, Peter J., Hautaniemi, Sampsa, Sorger, Peter K., Swisher, Elizabeth M., D’Andrea, Alan D., Konstantinopoulos, Panagiotis A.

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972 Platinum-based chemotherapy reverses human MDSC phenotype and suppressive activity on CD8+ T cells von Ding, Yueyun, Schrand, Ailem, DeBettencourt, Joe, Lako, Ana, Rai, Sharmila Chamling, Tauras, Christine, Bleicher, Zoe, Consedine, Timothy, George, Sangeeth, Balli, David, Simpson, Tyler, Geese, William J, Bhatt, Rupal, Chen, Benjamin, Ramirez-Alejo, Noe

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Society for Immunotherapy of Cancer: updates and best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) image analysis and data sharing von Taube, Janis M, Sunshine, Joel C, Angelo, Michael, Akturk, Guray, Eminizer, Margaret, Engle, Logan L, Ferreira, Cláudia S, Gnjatic, Sacha, Green, Benjamin, Greenbaum, Shirley, Greenwald, Noah F, Hedvat, Cyrus V, Hollmann, Travis J, Jiménez-Sánchez, Daniel, Korski, Konstanty, Lako, Ana, Parra, Edwin R, Rebelatto, Marlon C, Rimm, David L, Rodig, Scott J, Rodriguez-Canales, Jamie, Roskes, Jeffrey S, Schalper, Kurt A, Schenck, Emanuel, Steele, Keith E, Surace, Michael J, Szalay, Alexander S, Tetzlaff, Michael T, Wistuba, Ignacio I, Yearley, Jennifer H, Bifulco, Carlo B

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Correction: MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells von Wang, Yubao, Li, Young-Mi, Baitsch, Lukas, Huang, Alan, Xiang, Yi, Tong, Haoxuan, Lako, Ana, Von, Thanh, Choi, Christine, Lim, Elgene, Min, Junxia, Li, Li, Stegmeier, Frank, Schlegel, Robert, Eck, Michael J, Gray, Nathanael S, Mitchison, Timothy J, Zhao, Jean J

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700 Increasing MHC-I expression to potentiate immune checkpoint blockade therapy von Gu, Shengqing, Zhang, Wubing, Wang, Xiaoqing, Jiang, Peng, Traugh, Nicole, Li, Ziyi, Meyer, Clifford, Stewig, Blair, Xie, Yingtian, Bu, Xia, Manos, Michael, Font-Tello, Alba, Gjini, Evisa, Lako, Ana, Lim, Klothilda, Conway, Jake, Tewari, Alok, Zeng, Zexian, Sahu, Avinash Das, Tokheim, Collin, Weirather, Jason, Fu, Jingxin, Zhang, Yi, Kroger, Benjamin, Liang, Jin Hua, Cejas, Paloma, Freeman, Gordon, Rodig, Scott, Long, Henry, Gewurz, Benjamin, Stephen Hodi, F., Brown, Myles, Shirley Liu, X

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733 Integrative molecular profiling of high-grade primary prostate cancer identifies patients with a biomarker profile that favors the combination of standard of care (SOC) therapy... von Gjini, Evisa, Trillo-Tinoco, Jimena, Browne, Andrew, Powles, Ryan, Wang, Tai, Tauras, Christine, Lako, Ana, Ferrer-Luna, Ruben, Bleicher, Zoe, Consedine, Timothy, Zhou, Chensheng, Kelemen, Evan, Lewin, Anne, King, Catherine, Bhattacharya, Sumit, Bell-Temin, Harris, Dongre, Ashok, Nelson, David, Hatzis, Christos, Macisaac, Kenzie, Towfic, Fadi, Chen, Benjamin, Bowden, Michaela

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