Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12) von Navia-Paldanius, Dina, Savinainen, Juha R., Laitinen, Jarmo T.

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Biochemical and pharmacological characterization of the human lymphocyte antigen B-associated transcript 5 (BAT5/ABHD16A) von Savinainen, Juha R, Patel, Jayendra Z, Parkkari, Teija, Navia-Paldanius, Dina, Marjamaa, Joona J T, Laitinen, Tuomo, Nevalainen, Tapio, Laitinen, Jarmo T

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Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL) von Ahamed, Muneer, Attili, Bala, van Veghel, Daisy, Ooms, Maarten, Berben, Philippe, Celen, Sofie, Koole, Michel, Declercq, Lieven, Savinainen, Juha R., Laitinen, Jarmo T., Verbruggen, Alfons, Bormans, Guy

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Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12) von Parkkari, Teija, Haavikko, Raisa, Laitinen, Tuomo, Navia-Paldanius, Dina, Rytilahti, Roosa, Vaara, Miia, Lehtonen, Marko, Alakurtti, Sami, Yli-Kauhaluoma, Jari, Nevalainen, Tapio, Savinainen, Juha R, Laitinen, Jarmo T

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Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) von Korhonen, Jani, Kuusisto, Anne, van Bruchem, John, Patel, Jayendra Z., Laitinen, Tuomo, Navia-Paldanius, Dina, Laitinen, Jarmo T., Savinainen, Juha R., Parkkari, Teija, Nevalainen, Tapio J.

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Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography–electrospray tandem mass spectrometry von Aaltonen, Niina, Laitinen, Jarmo T., Lehtonen, Marko

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High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated... von Aaltonen, Niina, Singha, Prosanta K, Jakupović, Hermina, Wirth, Thomas, Samaranayake, Haritha, Pasonen-Seppänen, Sanna, Rilla, Kirsi, Varjosalo, Markku, Edgington-Mitchell, Laura E, Kasperkiewicz, Paulina, Drag, Marcin, Kälvälä, Sara, Moisio, Eemeli, Savinainen, Juha R, Laitinen, Jarmo T

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Screening of Various Hormone-Sensitive Lipase Inhibitors as Endocannabinoid-Hydrolyzing Enzyme Inhibitors von Minkkilä, Anna, Savinainen, Juha R., Käsnänen, Heikki, Xhaard, Henri, Nevalainen, Tapio, Laitinen, Jarmo T., Poso, Antti, Leppänen, Jukka, Saario, Susanna M.

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Monoglyceride Lipase as an Enzyme Hydrolyzing 2-Arachidonoylglycerol von Saario, Susanna M., Laitinen, Jarmo T.

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An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A 1 and cannabinoid CB 1 receptors von Savinainen, Juha R, Saario, Susanna M, Niemi, Riku, Järvinen, Tomi, Laitinen, Jarmo T

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Virtual Screening of Novel CB2 Ligands Using a Comparative Model of the Human Cannabinoid CB2 Receptor von Salo, Outi M. H, Raitio, Katri H, Savinainen, Juha R, Nevalainen, Tapio, Lahtela-Kakkonen, Maija, Laitinen, Jarmo T, Järvinen, Tomi, Poso, Antti

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Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL) von Savinainen, Juha R., Kansanen, Emilia, Pantsar, Tatu, Navia-Paldanius, Dina, Parkkari, Teija, Lehtonen, Marko, Laitinen, Tuomo, Nevalainen, Tapio, Poso, Antti, Levonen, Anna-Liisa, Laitinen, Jarmo T.

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Chiral 1,3,4-Oxadiazol-2-ones as Highly Selective FAAH Inhibitors von Patel, Jayendra Z, Parkkari, Teija, Laitinen, Tuomo, Kaczor, Agnieszka A, Saario, Susanna M, Savinainen, Juha R, Navia-Paldanius, Dina, Cipriano, Mariateresa, Leppänen, Jukka, Koshevoy, Igor O, Poso, Antti, Fowler, Christopher J, Laitinen, Jarmo T, Nevalainen, Tapio

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Evaluation of FASN inhibitors by a versatile toolkit reveals differences in pharmacology between human and rodent FASN preparations and in antiproliferative efficacy in vitro vs. i... von Singha, Prosanta K., Mäklin, Kiira, Vihavainen, Taina, Laitinen, Tuomo, Nevalainen, Tapio J., Patil, Mahadeo R., Tonduru, Arun K., Poso, Antti, Laitinen, Jarmo T., Savinainen, Juha R.

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In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048) von Aaltonen, Niina, Kedzierska, Ewa, Orzelska-Górka, Jolanta, Lehtonen, Marko, Navia-Paldanius, Dina, Jakupovic, Hermina, Savinainen, Juha R., Nevalainen, Tapio, Laitinen, Jarmo T., Parkkari, Teija, Gynther, Mikko

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Visualization of 2‐arachidonoylglycerol accumulation and cannabinoid CB1 receptor activity in rat brain cryosections by functional autoradiography von Palomäki, Ville A. B., Lehtonen, Marko, Savinainen, Juha R., Laitinen, Jarmo T.

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The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D–lysophosphatidic acid receptor axis and 5‐HT 1A receptors in rat brain sect... von Palomäki, Ville A B, Laitinen, Jarmo T

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A Sensitive and Versatile Fluorescent Activity Assay for ABHD12 von Savinainen, Juha R., Navia-Paldanius, Dina, Laitinen, Jarmo T.

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A Sensitive and Versatile Fluorescent Activity Assay for ABHD6 von Savinainen, Juha R., Navia-Paldanius, Dina, Laitinen, Jarmo T.

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Exposure to a 50-Hz Magnetic Field Induces a Circadian Rhythm in 6-hydroxymelatonin Sulfate Excretion in Mice von Kumlin, Timo, Heikkinen, Päivi, Laitinen, Jarmo T., Juutilainen, Jukka

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