P 136 Brain network analysis of EEG data in the service of clinical assessment – utilizing big data and prior theoretical knowledge to identify a biomarker for mTBI in adolscents von Reches, A., Or-ly, H., Weiss, M., Stern, Y., Baumeister, J.C., Foss, K.B., Ellis, J., Laish, B., Laufer, O., Sadeh, B., Ettinger, M., Arthur, T., Shaham, G., Myer, G., Kehat, O., Shani-Hershkovich, R., Peremen, Z., Geva, A.

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Mycosis fungoides‐derived exosomes promote cell motility and are enriched with microRNA‐155 and microRNA‐1246, and their plasma‐cell‐free expression may serve as a potential biomar... von Moyal, L., Arkin, C., Gorovitz‐Haris, B., Querfeld, C., Rosen, S., Knaneh, J., Amitay‐Laish, I., Prag‐Naveh, H., Jacob‐Hirsch, J., Hodak, E.

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Unilesional mycosis fungoides is associated with increased expression of microRNA‐17~92 and T helper 1 skewing von Moyal, L., Gorovitz‐Haris, B., Yehezkel, S., Jacob‐Hirsch, J., Bershtein, V., Barzilai, A., Rotem, C., Sherman, S., Amitay‐Laish, I., Feinmesser, M., Hodak, E.

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Treatment of early‐stage mycosis fungoides: results from the PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) study von Quaglino, P., Prince, H.M., Cowan, R., Vermeer, M., Papadavid, E., Bagot, M., Servitjie, O., Berti, E., Guenova, E., Stadler, R., Querfeld, C., Busschots, A.M., Hodak, E., Patsatsi, A., Sanches, J., Maule, M., Yoo, J., Kevin, M., Fava, P., Ribero, S., Zocchi, L., Rubatto, M., Fierro, M.T., Wehkamp, U., Marshalko, M., Mitteldorf, C., Akilov, O., Ortiz‐Romero, P., Estrach, T., Vakeva, L., Enz, P.A., Wobser, M., Bayne, M., Jonak, C., Rubeta, M., Forbes, A., Bates, A., Battistella, M., Amel‐Kashipaz, R., Vydianath, B., Combalia, A., Georgiou, E., Hauben, E., Hong, E.K., Jost, M., Knobler, R., Amitay‐Laish, I., Miyashiro, D., Cury‐Martins, J., Martinez, X., Muniesa, C., Prag‐Naveh, H., Stratigos, A., Nikolaou, V., Quint, K., Ram‐Wolff, C., Rieger, K., Stranzenbach, R., Szepesi, Á., Alberti‐Violetti, S., Felicity, E., Cerroni, L., Kempf, W., Whittaker, S., Willemze, R., Kim, Y., Scarisbrick, J.J.

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Stage-dependent Increase in Expression of miR-155 and Ki-67 and Number of Tumour-associated Inflammatory Cells in Folliculotropic Mycosis Fungoides von Atzmony, Lihi, Moyal, Lilach, Feinmesser, Meora, Gorovitz, Batya, Hirshberg, Avraham, Amitay-Laish, Iris, Prag-Naveh, Hadas, Barzilai, Aviv, Hodak, Emmilia

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A-152 Dissecting the role of CXCR4 in mycosis fungoides: from gene editing to therapeutic molecule von Moyal, L., Da'adoosh, B., Gorovitz, B., Mironovich, A., Omar, R., Khoury, H., Tsvetkova, M., Aronovich, A., Amitay-Laish, I., Naveh, H. Prag, Buzhansky, L., Shankar, S., Binyamini, R., Hodak, E.

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Reduction in operator radiation exposure during transradial coronary procedures using a simple lead rectangle von Osherov, Azriel B., Bruoha, Sharon, Laish Farkash, Avishag, Paul, Gideon, Orlov, Ian, Katz, Amos, Jafari, Jamal

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P119 Hereditary Colorectal Cancer Syndromes and Inflammatory Bowel Diseases: an ECCO CONFER Multicenter Case Series von Barberio, B, Savarino, E, Verstockt, B, Fumery, M, Pugliese, D, Bertani, L, Buda, A, Dragoni, G, Goren, I, Laish, I, Spinelli, A, Teich, N, Truyens, M, Ellul, P

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Hereditary Colorectal Cancer Syndromes and Inflammatory Bowel Diseases: an ECCO CONFER Multicenter Case Series von Barberio, B., Savarino, E., Verstockt, B., Fumery, Mathurin, Pugliese, D., Bertani, L., Buda, A., Dragoni, G., Goren, I., Laish, I., Spinelli, A., Teich, N., Truyens, M., Ellul, P.

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Unilesional mycosis fungoides is associated with increased expression of micro RNA ‐17~92 and T helper 1 skewing von Moyal, L., Gorovitz‐Haris, B., Yehezkel, S., Jacob‐Hirsch, J., Bershtein, V., Barzilai, A., Rotem, C., Sherman, S., Amitay‐Laish, I., Feinmesser, M., Hodak, E.

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The precede consortium: A longitudinal international cohort study of individuals with a high-risk of pancreatic cancer von García García de Paredes, A., Katona, B., Zogopoulos, G., Brand, R., Kaul, V., Earl, J., Tempero, M., Kupfer, S., Paiella, S., Farrell, J., Sears, R., Sheppard, B., Grossberg, A., Idos, G., Chung, D., Golan, T., Friedman, E., Laish, I., Kwon, R., Stoffel, E., Merchant, N., Sussman, D., Brentnall, T., Gaddam, S., Jeter, J., Klute, K., Lowy, A., Liau, J., Lindberg, J., Permuth, J., Kastrinos, F., Bi, Y., Carpizo, D., Lin, J., Schrader, I., Lucas, A., Wadlow, R., Greenhalf, W., Shan, Y., Simeone, D.

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030 - Cancer-associated fibroblasts: characterization and role in mycosis fungoides lesions von Moyal, L., Aronovich, A., Gorovitz, B., Forer, Y., Laurent, L., Amitay-Laish, I., Prag Naveh, H., Ad-El, D., Yaacobi, D., Barel, E., Litwin, A., Maron, L., Hodak, E.

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Cancer-associated fibroblasts: characterization and role in mycosis fungoides lesions von Moyal, L., Aronovich, A., Gorovitz, B., Forer, Y., Laurent, L., Amitay-Laish, I., Prag Naveh, H., Ad-El, D., Yaacobi, D., Barel, E., Litwin, A., Maron, L., Hodak, E.

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Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospec... von Haupt, Saskia, Seppälä, Toni T., Sampson, Julian R., Sunde, Lone, Bernstein, Inge, Jenkins, Mark A., Engel, Christoph, Aretz, Stefan, Nielsen, Maartje, Capella, Gabriel, Balaguer, Francesc, Evans, Dafydd Gareth, Burn, John, Holinski-Feder, Elke, Bonanni, Bernardo, Lindblom, Annika, Levi, Zohar, Macrae, Finlay, Winship, Ingrid, Plazzer, John-Paul, Sijmons, Rolf, Della Valle, Adriana, Heinimann, Karl, Dębniak, Tadeusz, Fruscio, Robert, Katz, Lior H., Laish, Ido, Vainer, Elez, Carraro, Dirce Maria, Monahan, Kevin, Half, Elizabeth, Stakelum, Aine, Winter, Des, Kennelly, Rory, Gluck, Nathan, Sheth, Harsh, Abu-Freha, Naim, Greenblatt, Marc, Bohorquez, Mabel, Cavestro, Giulia Martina, Lino-Silva, Leonardo S., Horisberger, Karoline, Nascimento, Ivana do, Thomas, Huw, Rossi, Norma Teresa, Apolinário da Silva, Leandro, Zaránd, Attila, Ruiz-Bañobre, Juan, Heuveline, Vincent, Mecklin, Jukka-Pekka, Renkonen-Sinisalo, Laura, Peltomäki, Päivi, Madsen, Mia Gebauer, Burgdorf, Stefan Kobbelgaard, Hopper, John L., Win, Aung Ko, Haile, Robert W., Lindor, Noralane, Le Marchand, Loïc, Newcomb, Polly A., Figueiredo, Jane, Buchanan, Daniel D., Rahner, Nils, Schröck, Evelin, Steinke-Lange, Verena, Schmiegel, Wolff, Vangala, Deepak, Perne, Claudia, Hüneburg, Robert, Redler, Silke, Büttner, Reinhard, Weitz, Jürgen, Pineda, Marta, Duenas, Nuria, Vidal, Joan Brunet, Moreira, Leticia, Sánchez, Ariadna, Hovig, Eivind, Nakken, Sigve, Green, Kate, Lalloo, Fiona, Hill, James, Crosbie, Emma, Mints, Miriam, Goldberg, Yael, Tjandra, Douglas, ten Broeke, Sanne W., Kariv, Revital, Rosner, Guy, Advani, Suresh H., Thomas, Lidiya, Shah, Pankaj, Shah, Mithun, Neffa, Florencia, Esperon, Patricia, Pavicic, Walter, Torrezan, Giovana Tardin, Bassaneze, Thiago, Moslein, Gabriela, Moller, Pål

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Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium von Møller, Pål, Seppälä, Toni, Dowty, James G, Haupt, Saskia, Dominguez-Valentin, Mev, Sunde, Lone, Bernstein, Inge, Engel, Christoph, Aretz, Stefan, Nielsen, Maartje, Capella, Gabriel, Evans, Dafydd Gareth, Burn, John, Holinski-Feder, Elke, Bertario, Lucio, Bonanni, Bernardo, Lindblom, Annika, Levi, Zohar, Macrae, Finlay, Winship, Ingrid, Plazzer, John-Paul, Sijmons, Rolf, Laghi, Luigi, Valle, Adriana Della, Heinimann, Karl, Half, Elizabeth, Lopez-Koestner, Francisco, Alvarez-Valenzuela, Karin, Scott, Rodney J, Katz, Lior, Laish, Ido, Vainer, Elez, Vaccaro, Carlos Alberto, Carraro, Dirce Maria, Gluck, Nathan, Abu-Freha, Naim, Stakelum, Aine, Kennelly, Rory, Winter, Des, Rossi, Benedito Mauro, Greenblatt, Marc, Bohorquez, Mabel, Sheth, Harsh, Tibiletti, Maria Grazia, Lino-Silva, Leonardo S, Horisberger, Karoline, Portenkirchner, Carmen, Nascimento, Ivana, Rossi, Norma Teresa, da Silva, Leandro Apolinário, Thomas, Huw, Zaránd, Attila, Mecklin, Jukka-Pekka, Pylvänäinen, Kirsi, Renkonen-Sinisalo, Laura, Lepisto, Anna, Peltomäki, Päivi, Therkildsen, Christina, Lindberg, Lars Joachim, Thorlacius-Ussing, Ole, von Knebel Doeberitz, Magnus, Loeffler, Markus, Rahner, Nils, Steinke-Lange, Verena, Schmiegel, Wolff, Vangala, Deepak, Perne, Claudia, Hüneburg, Robert, de Vargas, Aída Falcón, Latchford, Andrew, Gerdes, Anne-Marie, Backman, Ann-Sofie, Guillén-Ponce, Carmen, Snyder, Carrie, Lautrup, Charlotte K, Amor, David, Palmero, Edenir, Stoffel, Elena, Duijkers, Floor, Hall, Michael J, Hampel, Heather, Williams, Heinric, Okkels, Henrik, Lubiński, Jan, Reece, Jeanette, Ngeow, Joanne, Guillem, Jose G, Arnold, Julie, Wadt, Karin, Monahan, Kevin, Senter, Leigha, Rasmussen, Lene J, van Hest, Liselotte P, Ricciardiello, Luigi, Kohonen-Corish, Maija R J, Ligtenberg, Marjolijn J L, Southey, Melissa, Aronson, Melyssa, Zahary, Mohd N, Samadder, N Jewel

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Treatment of early-stage mycosis fungoides: results from the PROspective Cutaneous Lymphoma International Study (PROCLIPI study) von Quaglino, P., Prince, H.M., Cowan, R., Vermeer, M., Papadavid, L., Bagot, M., Servitjie, O., Berti, E., Guenova, E., Stadler, R., Querfeld, C., Busschots, A.M., Hodak, E., Patsatsi, A., Sanches, J., Maule, M., Yoo, J., Kevin, M., Fava, P., Ribero, S., Zocchi, L., Rubatto, M., Fierro, M.T., Wehkamp, U., Marshalko, M., Mitteldorf, C., Akilov, O., Ortiz-Romero, P., Estrach, T., Vakeva, L., Enz, P.A., Wobser, M., Bayne, M., Jonak, C., Rubeta, M., Forbes, A., Bates, A., Battistella, M., Amel-Kashipaz, R., Vydianath, B., Combalia, A., Georgiou, E., Hauben, E., Hong, E.K., Jost, M., Knobler, R., Amitay-Laish, I., Miyashiro, D., Cury-Martins, J., Martinez, X., Muniesa, C., Prag-Naveh, H., Nikolaou, V., Quint, K., Ram-Wolff, C., Rieger, K., Stranzenbach, R., Szepesi, Á., Alberti-Violetti, S., Felicity, E., Cerroni, L., Kempf, W., Whittaker, S., Willemze, R., Kim, Y., Scarisbrick, J.J.

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Treatment of early-stage mycosis fungoides: results from the PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) study von Quaglino, P, Prince, H.M, Cowan, R, Vermeer, M, Papadavid, E, Bagot, M, Servitjie, O, Berti, E, Guenova, E, Stadler, R, Querfeld, C, Busschots, A.M, Hodak, E, Patsatsi, A, Sanches, J, Maule, M, Yoo, J, Kevin, M, Fava, P, Ribero, S, Zocchi, L, Rubatto, M, Fierro, M.T, Wehkamp, U, Marshalko, M, Mitteldorf, C, Akilov, O, Ortiz-Romero, P, Estrach, T, Vakeva, L, Enz, P.A, Wobser, M, Bayne, M, Jonak, C, Rubeta, M, Forbes, A, Bates, A, Battistella, M, Amel-Kashipaz, R, Vydianath, B, Combalia, A, Georgiou, E, Hauben, E, Hong, E.K, Jost, M, Knobler, R, Amitay-Laish, I, Miyashiro, D, Cury-Martins, J, Martinez, X, Muniesa, C, Prag-Naveh, H, Stratigos, A, Nikolaou, V, Quint, K, Ram-Wolff, C, Rieger, K, Stranzenbach, R, Szepesi, A, Alberti-Violetti, S, Felicity, E, Cerroni, L, Kempf, W, Whittaker, S, Willemze, R, Kim, Y, Scarisbrick, J.J

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Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium von Seppala, T, Dowty, JG, Haupt, S, Dominguez-Valentin, M, Engel, C, Aretz, S, Nielsen, M, Capella, G, Burn, J, Bertario, L, Bonanni, B, Lindblom, A, Macrae, F, Winship, I, Heinimann, K, Half, E, Lopez-Koestner, F, Katz, L, Laish, I, Vaccaro, CA, Carraro, DM, Gluck, N, Abu-Freha, N, Kennelly, R, Winter, D, Greenblatt, M, Sheth, H, Tibiletti, MG, Horisberger, K, Portenkirchner, C, Da Silva, LA, Thomas, H, Zarand, A, Renkonen-Sinisalo, L, Peltomaki, P, Loeffler, M, Rahner, N, Schmiegel, W, Vangala, D, Hueneburg, R, De Vargas, AF, Gerdes, A-M, Backman, A-S, Lautrup, CK, Amor, D, Palmero, E, Stoffel, E, Duijkers, F, Hall, MJ, Williams, H, Okkels, H, Lubinski, J, Reece, J, Guillem, JG, Wadt, K, Monahan, K, Rasmussen, LJ, Ricciardiello, L, Kohonen-Corish, MRJ, Southey, M, Samadder, NJ, Hoogerbrugge, N, Morrison, PJ, Chen-Shtoyerman, R, Ankathil, R, Pai, R, Ward, R, Parry, S, Debniak, T, Caldes, T, Yamaguchi, T, Barca-Tierno, V, Cavestro, GM, Weitz, J, Redler, S, Buettner, R, Heuveline, V, Hopper, JL, Lindor, N, Newcomb, PA, Figueiredo, J, Buchanan, DD, Thibodeau, SN, Ten Broeke, SW, Hovig, E, Brunet, J, Lalloo, F, Newton, K, Mints, M, Tjandra, D, Neffa, F, Esperon, P, Kariv, R, Rosner, G, Pavicic, WH, Torrezan, GT, Bassaneze, T, Ahadova, A, Sampson, JR, Jenkins, MA

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Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospec... von Dominguez-Valentin, M, Seppälä, TT, Sampson, JR, Sunde, L, Bernstein, I, Engel, C, Aretz, S, Nielsen, M, Capella, G, Balaguer, F, Evans, DG, Burn, J, Holinski-Feder, E, Bertario, L, Bonanni, B, Levi, Z, Macrae, F, Winship, I, Plazzer, J-P, Sijmons, R, Laghi, L, Heinimann, K, Dębniak, T, Fruscio, R, Lopez-Koestner, F, Alvarez-Valenzuela, K, Katz, LH, Laish, I, Vainer, E, Carraro, DM, Monahan, K, Half, E, Stakelum, A, Winter, D, Kennelly, R, Gluck, N, Sheth, H, Greenblatt, M, Rossi, BM, Bohorquez, M, Cavestro, GM, Lino-Silva, LS, Horisberger, K, Tibiletti, MG, Nascimento, ID, Thomas, H, Rossi, NT, Apolinário da Silva, L, Zaránd, A, Ruiz-Bañobre, J, Heuveline, V, Mecklin, J-P, Pylvänäinen, K, Renkonen-Sinisalo, L, Lepistö, A, Peltomäki, P, Therkildsen, C, Madsen, MG, Hopper, JL, Win, AK, Haile, RW, Lindor, N, Gallinger, S, Newcomb, PA, Figueiredo, J, Thibodeau, SN, Von Knebel Doeberitz, M, Loeffler, M, Schröck, E, Steinke-Lange, V, Schmiegel, W, Vangala, D, Perne, C, Hüneburg, R, Redler, S, Büttner, R, Weitz, J, Duenas, N, Vidal, JB, Moreira, L, Sánchez, A, Hovig, E, Green, K, Lalloo, F, Hill, J, Goldberg, Y, Tjandra, D, Ten Broeke, SW, Kariv, R, Rosner, G, Advani, SH, Shah, P, Shah, M, Neffa, F, Pavicic, W, Torrezan, GT, Bassaneze, T, Martin, CA, Moslein, G, Moller, P

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Abstracts: Genetics in arrhythmias von Posch, M. G., Perrot, A., Boldt, L. H., Lehmkuhl, H. B., Hetzer, R., Dietz, R., Haverkamp, W., Ozcelik, C., Lohse, M., Polotzki, M., Rolf, S., Nof, E., Laish- Farkash, A., Marek, D., Pras, E., Eldar, M., Antzelevitch, C., Glikson, M., Luria, D., Laish-Farkash, A., Marek-Yagel, D., Viskin, S., Belhassen, B., Arad, M., Bhuiyan, Z. A., Rosso, R., Wilde, A. A. M., Duthoit, G., Fressart, V., Simon, F., Hidden-Lucet, F., Lacotte, J., Lecarpentier, Y., Frank, R., Hebert, J.- L.

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