Understanding activity of butyrate at a cellular level von Chakraborty, Prapti, Laird, Angela S

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Aberrant Cerebellar Circuitry in the Spinocerebellar Ataxias von Robinson, Katherine J., Watchon, Maxinne, Laird, Angela S.

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Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy von Laird, Angela S, Van Hoecke, Annelies, De Muynck, Louis, Timmers, Mieke, Van den Bosch, Ludo, Van Damme, Philip, Robberecht, Wim

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EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans von Van Hoecke, Annelies, Schoonaert, Lies, Lemmens, Robin, Timmers, Mieke, Staats, Kim A, Laird, Angela S, Peeters, Elke, Philips, Thomas, Goris, An, Dubois, Bénédicte, Andersen, Peter M, Al-Chalabi, Ammar, Thijs, Vincent, Turnley, Ann M, van Vught, Paul W, Veldink, Jan H, Hardiman, Orla, Van Den Bosch, Ludo, Gonzalez-Perez, Paloma, Van Damme, Philip, Brown, Robert H, van den Berg, Leonard H, Robberecht, Wim

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Machado Joseph disease severity is linked with gut microbiota alterations in transgenic mice von Gamage, Hasinika K.A.H., Robinson, Katherine J., Luu, Luan, Paulsen, Ian T., Laird, Angela S.

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Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy von Watchon, Maxinne, Yuan, Kristy C, Mackovski, Nick, Svahn, Adam J, Cole, Nicholas J, Goldsbury, Claire, Rinkwitz, Silke, Becker, Thomas S, Nicholson, Garth A, Laird, Angela S

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Conserved anti-inflammatory effects and sensing of butyrate in zebrafish von Cholan, Pradeep Manuneedhi, Han, Alvin, Woodie, Brad R., Watchon, Maxinne, Kurz, Angela R. M., Laird, Angela S., Britton, Warwick J., Ye, Lihua, Holmes, Zachary C., McCann, Jessica R., David, Lawrence A., Rawls, John F., Oehlers, Stefan H.

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Spermidine treatment: induction of autophagy but also apoptosis? von Watchon, Maxinne, Wright, Amanda L, Ahel, Holly I, Robinson, Katherine J, Plenderleith, Stuart K, Kuriakose, Andrea, Yuan, Kristy C, Laird, Angela S

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Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3 von Robinson, Katherine J., Tym, Madelaine C., Hogan, Alison, Watchon, Maxinne, Yuan, Kristy C., Plenderleith, Stuart K., Don, Emily K., Laird, Angela S.

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Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype von Hogan, Alison L, Don, Emily K, Rayner, Stephanie L, Lee, Albert, Laird, Angela S, Watchon, Maxinne, Winnick, Claire, Tarr, Ingrid S, Morsch, Marco, Fifita, Jennifer A, Gwee, Serene S L, Formella, Isabel, Hortle, Elinor, Yuan, Kristy C, Molloy, Mark P, Williams, Kelly L, Nicholson, Garth A, Chung, Roger S, Blair, Ian P, Cole, Nicholas J

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Autophagy Function and Benefits of Autophagy Induction in Models of Spinocerebellar Ataxia Type 3 von Watchon, Maxinne, Luu, Luan, Plenderleith, Stuart K, Yuan, Kristy C, Laird, Angela S

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Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo von Watchon, Maxinne, Luu, Luan, Robinson, Katherine J., Yuan, Kristy C., De Luca, Alana, Suddull, Hannah J., Tym, Madelaine C., Guillemin, Gilles J., Cole, Nicholas J., Nicholson, Garth A., Chung, Roger S., Lee, Albert, Laird, Angela S.

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A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3 von Robinson, Katherine J., Yuan, Kristy, Plenderleith, Stuart K., Watchon, Maxinne, Laird, Angela S.

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The deubiquitinase function of ataxin-3 and its role in the pathogenesis of Machado-Joseph disease and other diseases von Potapenko, Anastasiya, Davidson, Jennilee M, Lee, Albert, Laird, Angela S

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Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis Pathway: A Workflow to Scr... von Cheng, Flora, De Luca, Alana, Hogan, Alison L., Rayner, Stephanie L., Davidson, Jennilee M., Watchon, Maxinne, Stevens, Claire H., Munoz, Sonia Sanz, Ooi, Lezanne, Yerbury, Justin J., Don, Emily K., Fifita, Jennifer A., Villalva, Maria D., Suddull, Hannah, Chapman, Tyler R., Hedl, Thomas J., Walker, Adam K., Yang, Shu, Morsch, Marco, Shi, Bingyang, Blair, Ian P., Laird, Angela S., Chung, Roger S., Lee, Albert

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Mutant human FUS Is ubiquitously mislocalized and generates persistent stress granules in primary cultured transgenic zebrafish cells von Acosta, Jamie Rae, Goldsbury, Claire, Winnick, Claire, Badrock, Andrew P, Fraser, Stuart T, Laird, Angela S, Hall, Thomas E, Don, Emily K, Fifita, Jennifer A, Blair, Ian P, Nicholson, Garth A, Cole, Nicholas J

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The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models von Parakh, Sonam, Shadfar, Sina, Perri, Emma R., Ragagnin, Audrey M.G., Piattoni, Claudia V., Fogolín, Mariela B., Yuan, Kristy C., Shahheydari, Hamideh, Don, Emily K., Thomas, Collen J., Hong, Yuning, Comini, Marcelo A., Laird, Angela S., Spencer, Damian M., Atkin, Julie D.

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Long polyglutamine tracts impair the autophagy protein quality control pathway von Laird, Angela S.

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Butyrate as a potential therapeutic agent for neurodegenerative disorders von Chakraborty, Prapti, Gamage, Hasinika K.A.H., Laird, Angela S.

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Tissue-specific models of spinal muscular atrophy confirm a critical role of SMN in motor neurons from embryonic to adult stages von Laird, Angela S, Mackovski, Nikolce, Rinkwitz, Silke, Becker, Thomas S, Giacomotto, Jean

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