Defining actionable mutations for oncology therapeutic development von Carr, T. Hedley, McEwen, Robert, Dougherty, Brian, Johnson, Justin H., Dry, Jonathan R., Lai, Zhongwu, Ghazoui, Zara, Laing, Naomi M., Hodgson, Darren R., Cruzalegui, Francisco, Hollingsworth, Simon J., Barrett, J. Carl

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Discovery of a Novel Class of Dimeric Smac Mimetics as Potent IAP Antagonists Resulting in a Clinical Candidate for the Treatment of Cancer (AZD5582) von Hennessy, Edward J, Adam, Ammar, Aquila, Brian M, Castriotta, Lillian M, Cook, Donald, Hattersley, Maureen, Hird, Alexander W, Huntington, Christopher, Kamhi, Victor M, Laing, Naomi M, Li, Danyang, MacIntyre, Terry, Omer, Charles A, Oza, Vibha, Patterson, Troy, Repik, Galina, Rooney, Michael T, Saeh, Jamal C, Sha, Li, Vasbinder, Melissa M, Wang, Haiyun, Whitston, David

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A Smac mimetic augments the response of urothelial cancer cells to gemcitabine and cisplatin von Lee, Eugene K, Jinesh G, Goodwin, Laing, Naomi M, Choi, Woonyoung, McConkey, David J, Kamat, Ashish M

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Discovery of aminopiperidine-based Smac mimetics as IAP antagonists von Hennessy, Edward J., Saeh, Jamal C., Sha, Li, MacIntyre, Terry, Wang, Haiyun, Larsen, Nicholas A., Aquila, Brian M., Ferguson, Andrew D., Laing, Naomi M., Omer, Charles A.

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Structure-based design and synthesis of tricyclic IAP (Inhibitors of Apoptosis Proteins) inhibitors von Hird, Alexander W., Aquila, Brian M., Block, Michael H., Hennessy, Edward J., Kamhi, Victor M., Omer, Charles A., Laing, Naomi M., Saeh, Jamal C., Sha, Li, Yang, Bin

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Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells von LAING, N. M, BELINSKY, M. G, KRUH, G. D, BELL, D. W, BOYD, J. T, BARONE, L, TESTA, J. R, TEW, K. D

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Coordinate changes in expression of protective genes in drug-resistant cells von Tew, Kenneth D, O’Brien, Miechelle, Laing, Naomi M, Shen, Hongxie

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Association of Estramustine Resistance in Human Prostatic Carcinoma Cells with Modified Patterns of Tubulin Expression von Sangrajrang, Suleeporn, Denoulet, Philippe, Laing, Naomi M, Tatoud, Roger, Millot, Guy, Calvo, Fabien, Tew, Kenneth D, Fellous, Arlette

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A Biomarker-enriched, Randomized Phase II Trial of Adavosertib (AZD1775) Plus Paclitaxel and Carboplatin for Women with Platinum-sensitive TP53-mutant Ovarian Cancer von Oza, Amit M., Estevez-Diz, Maria, Grischke, Eva-Maria, Hall, Marcia, Marme, Frederik, Provencher, Diane, Uyar, Denise, Weberpals, Johanne I., Wenham, Robert M., Laing, Naomi, Tracy, Michael, Freshwater, Tomoko, Lee, Mark A., Liu, Ji, Qiu, Jingjun, Rose, Shelonitda, Rubin, Eric H., Moore, Kathleen

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Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia von Restuadi, Restuadi, Garton, Fleur C, Benyamin, Beben, Lin, Tian, Williams, Kelly L, Vinkhuyzen, Anna, van Rheenen, Wouter, Zhu, Zhihong, Laing, Nigel G, Mather, Karen A, Sachdev, Perminder S, Ngo, Shyuan T, Steyn, Frederik J, Wallace, Leanne, Henders, Anjali K, Visscher, Peter M, Needham, Merrilee, Mathers, Susan, Nicholson, Garth, Rowe, Dominic B, Henderson, Robert D, McCombe, Pamela A, Pamphlett, Roger, Blair, Ian P, Wray, Naomi R, McRae, Allan F

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Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials von Axfors, Cathrine, Janiaud, Perrine, Schmitt, Andreas M., Van't Hooft, Janneke, Smith, Emily R., Haber, Noah A., Abayomi, Akin, Abduljalil, Manal, Abdulrahman, Abdulkarim, Acosta-Ampudia, Yeny, Aguilar-Guisado, Manuela, Al-Beidh, Farah, Alejandria, Marissa M., Alfonso, Rachelle N., Ali, Mohammad, AlQahtani, Manaf, AlZamrooni, Alaa, Anaya, Juan-Manuel, Ang, Mark Angelo C., Aomar, Ismael F., Argumanis, Luis E., Averyanov, Alexander, Baklaushev, Vladimir P., Balionis, Olga, Benfield, Thomas, Berry, Scott, Birocco, Nadia, Bonifacio, Lynn B., Bowen, Asha C., Bown, Abbie, Cabello-Gutierrez, Carlos, Camacho, Bernardo, Camacho-Ortiz, Adrian, Campbell-Lee, Sally, Cao, Damon H., Cardesa, Ana, Carnate, Jose M., Castillo, German Jr J., Cavallo, Rossana, Chowdhury, Fazle R., Chowdhury, Forhad U. H., Ciccone, Giovannino, Cingolani, Antonella, Climacosa, Fresthel Monica M., Compernolle, Veerle, Cortez, Carlo Francisco N., Neto, Abel Costa, D'Antico, Sergio, Daly, James, Danielle, Franca, Davis, Joshua S., De Rosa, Francesco Giuseppe, Denholm, Justin T., Denkinger, Claudia M., Desmecht, Daniel, Diaz-Coronado, Juan C., Diaz Ponce-Medrano, Juan A., Donneau, Anne-Francoise, Dumagay, Teresita E., Dunachie, Susanna, Dungog, Cecile C., Erinoso, Olufemi, Escasa, Ivy Mae S., Estcourt, Lise J., Evans, Amy, Evasan, Agnes L. M., Fareli, Christian J., Fernandez-Sanchez, Veronica, Galassi, Claudia, Gallo, Juan E., Garcia, Patricia J., Garcia, Patricia L., Garcia, Jesus A., Garigliany, Mutien, Garza-Gonzalez, Elvira, Gauiran, Deonne Thaddeus, Gaviria Garcia, Paula A., Giron-Gonzalez, Jose-Antonio, Gomez-Almaguer, David, Gordon, Anthony C., Gothot, Andre, Grass Guaqueta, Jeser Santiago, Green, Cameron, Grimaldi, David, Hammond, Naomi E., Harvala, Heli, Heralde, Francisco M., Herrick, Jesica, Higgins, Alisa M., Hills, Thomas E., Hines, Jennifer, Holm, Karin, Hoque, Ashraful, Hoste, Eric, Ignacio, Jose M., Ivanov, Alexander, Janssen, Maike, Jennings, Jeffrey H., Jha, Vivekanand, King, Ruby Anne N.

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Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis von Nabais, Marta F., Lin, Tian, Benyamin, Beben, Williams, Kelly L., Garton, Fleur C., Vinkhuyzen, Anna A. E., Zhang, Futao, Vallerga, Costanza L., Restuadi, Restuadi, Freydenzon, Anna, Zwamborn, Ramona A. J., Hop, Paul J., Robinson, Matthew R., Gratten, Jacob, Visscher, Peter M., Hannon, Eilis, Mill, Jonathan, Brown, Matthew A., Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Needham, Merrilee, Veldink, Jan H., Mathers, Susan, Nicholson, Garth, Rowe, Dominic B., Henderson, Robert D., McCombe, Pamela A., Pamphlett, Roger, Yang, Jian, Blair, Ian P., McRae, Allan F., Wray, Naomi R.

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Nephrocalcinosis (Enamel Renal Syndrome) Caused by Autosomal Recessive FAM20A Mutations von Jaureguiberry, Graciana, De la Dure-Molla, Muriel, Parry, David, Quentric, Mickael, Himmerkus, Nina, Koike, Toshiyasu, Poulter, James, Klootwijk, Enriko, Robinette, Steven L., Howie, Alexander J., Patel, Vaksha, Figueres, Marie-Lucile, Stanescu, Horia C., Issler, Naomi, Nicholson, Jeremy K., Bockenhauer, Detlef, Laing, Christopher, Walsh, Stephen B., McCredie, David A., Povey, Sue, Asselin, Audrey, Picard, Arnaud, Coulomb, Aurore, Medlar, Alan J., Bailleul-Forestier, Isabelle, Verloes, Alain, Le Caignec, Cedric, Roussey, Gwenaelle, Guiol, Julien, Isidor, Bertrand, Logan, Clare, Shore, Roger, Johnson, Colin, Inglehearn, Christopher, Al-Bahlani, Suhaila, Schmittbuhl, Matthieu, Clauss, François, Huckert, Mathilde, Laugel, Virginie, Ginglinger, Emmanuelle, Pajarola, Sandra, Spartà, Giuseppina, Bartholdi, Deborah, Rauch, Anita, Addor, Marie-Claude, Yamaguti, Paulo M., Safatle, Heloisa P., Acevedo, Ana Carolina, Martelli-Júnior, Hercílio, dos Santos Netos, Pedro E., Coletta, Ricardo D., Gruessel, Sandra, Sandmann, Carolin, Ruehmann, Denise, Langman, Craig B., Scheinman, Steven J., Ozdemir-Ozenen, Didem, Hart, Thomas C., Hart, P. Suzanne, Neugebauer, Ute, Schlatter, Eberhard, Houillier, Pascal, Gahl, William A., Vikkula, Miikka, Bloch-Zupan, Agnès, Bleich, Markus, Kitagawa, Hiroshi, Unwin, Robert J., Mighell, Alan, Berdal, Ariane, Kleta, Robert

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Augmentation of urothelial cancer cells' response to gemcitabine and cisplatin by a Smac mimetic von Lee, Eugene K., Gerald, Jinesh, Laing, Naomi, Choi, Woonyoung, McConkey, David James, Kamat, Ashish M.

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Abstract S1-01: TransCONFIRM: The correlative analysis of breast tumors from patients with advanced hormone receptor positive disease identifies a genetic signature associated with... von Jeselsohn, Rinath M, Barry, William T, Zhao, Jin, Buchwalter, Gilles, Guarducci, Cristina, Migliaccio, Ilenia, Biagioni, Chiara, Bonechi, Martina, Laing, Naomi, Rukazenkov, Yuri, Winer, Eric P, Brown, Myles, Di Leo, Angelo, Malorni, Luca

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Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling von Michaud, Neil R, Wang, Youzhen, McEachern, Kristen A, Jordan, Jerold J, Mazzola, Anne Marie, Hernandez, Axel, Jalla, Sanjoo, Chesebrough, Jon W, Hynes, Mark J, Belmonte, Matthew A, Wang, Lidong, Kang, Jaspal S, Jovanovic, Jelena, Laing, Naomi, Jenkins, David W, Hurt, Elaine, Liang, Meina, Frantz, Christopher, Hollingsworth, Robert E, Simeone, Diane M, Blakey, David C, Bedian, Vahe

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L’enseignement des traités autochtones dans une classe d’immersion française. L’apprentissage des thèmes reliés à la réconciliation dans un contexte français minoritaire... von Fortier-Fréçon, Naomi, Laing, Leia

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Activity-guided fractionation of the leaves of Ormosia sumatrana using a proteasome inhibition assay von Su, B.N, Hwang, B.Y, Chai, H, Carcache-Blanco, E.J, Kardono, L.B.S, Afriastini, J.J, Riswan, S, Wild, R, Laing, N, Farnsworth, N.R

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Nephrocalcinosis (Enamel Renal Syndrome) Caused by Autosomal Recessive FAM20A Mutations von JAUREGUIBERRY, Graciana, DE LA DURE-MOLLA, Muriel, PATEL, Vaksha, FIGUERES, Marie-Lucile, STANESCU, Horia C, ISSLER, Naomi, NICHOLSON, Jeremy K, BOCKENHAUER, Detlef, LAING, Christopher, WALSH, Stephen B, MCCREDIE, David A, POVEY, Sue, PARRY, David, ASSELIN, Audrey, PICARD, Arnaud, COULOMB, Aurore, MEDLAR, Alan J, BAILLEUL-FORESTIER, Isabelle, VERLOES, Alain, LE CAIGNEC, Cedric, ROUSSEY, Gwenaelle, GUIOL, Julien, ISIDOR, Bertrand, QUENTRIC, Mickael, LOGAN, Clare, SHORE, Roger, JOHNSON, Colin, INGLEHEARN, Christopher, AL-BAHLANI, Suhaila, SCHMITTBUHL, Matthieu, CLAUSS, François, HUCKERT, Mathilde, LAUGEL, Virginie, GINGLINGER, Emmanuelle, HIMMERKUS, Nina, PAJAROLA, Sandra, SPARTA, Giuseppina, BARTHOLDI, Deborah, RAUCH, Anita, ADDOR, Marie-Claude, YAMAGUTI, Paulo M, SAFATLE, Heloisa P, ACEVEDO, Ana Carolina, MARTELLI-JUNIOR, Hercílio, DOS SANTOS NETOS, Pedro E, KOIKE, Toshiyasu, COLETTA, Ricardo D, GRUESSEL, Sandra, SANDMANN, Carolin, RUEHMANN, Denise, LANGMAN, Craig B, SCHEINMAN, Steven J, OZDEMIR-OZENEN, Didem, HART, Thomas C, SUZANNE HART, P, NEUGEBAUER, Ute, POULTER, James, KLOOTWIJK, Enriko, ROBINETTE, Steven L, HOWIE, Alexander J

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COVID-19 first lockdown as a window into language acquisition: associations between caregiver-child activities and vocabulary gains von Kartushina, Natalia, Mani, Nivedita, Aslı, Aktan-Erciyes, Alaslani, Khadeejah, Aldrich, Naomi J, Almohammadi, Alaa, Alroqi, Haifa, Anderson, Lucy M, Andonova, Elena, Aussems, Suzanne, Babineau, Mireille, Barokova, Mihaela, Bergmann, Christina, Cashon, Cara, Custode, Stephanie, de Carvalho, Alex, Dimitrova, Nevena, Dynak, Agnieszka, Farah, Rola, Fennell, Christopher, Fiévet, Anne-Caroline, Frank, Michael C, Gavrilova, Margarita, Gendler-Shalev, Hila, Gibson, Shannon P, Golway, Katherine, Gonzalez-Gomez, Nayeli, Haman, Ewa, Hannon, Erin, Havron, Naomi, Hay, Jessica, Hendriks, Cielke, Horowitz-kraus, Tzipi, Kalashnikova, Marina, Kanero, Junko, Keller, Christina, Krajewski, Grzegorz, Laing, Catherine, Lundwall, Rebecca A, Łuniewska, Magdalena, Mieszkowska, Karolina, Munoz, Luis Eduardo, Nave, Karli, Olesen, Nonah, Perry, Lynn, Rowland, Caroline F, Santos Oliveira, Daniela, Shinskey, Jeanne, Veraksa, Aleksander N, Vincent, Kolbie, Zivan, Michal, Mayor, Julien

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