Editorial: The contribution of viruses and innate immune system in the pathogenesis of type 1 diabetes von Nigi, Laura, Laiho, Jutta E, Hyöty, Heikki, Dotta, Francesco

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Differential Detection of Encapsidated versus Unencapsidated Enterovirus RNA in Samples Containing Pancreatic Enzymes-Relevance for Diabetes Studies von Oikarinen, Maarit, Bertolet, Lori, Toniolo, Antonio, Oikarinen, Sami, Laiho, Jutta E., Pugliese, Alberto, Lloyd, Richard, Hyoty, Heikki

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Coxsackievirus B Persistence Modifies the Proteome and the Secretome of Pancreatic Ductal Cells von Lietzén, Niina, Hirvonen, Karoliina, Honkimaa, Anni, Buchacher, Tanja, Laiho, Jutta E., Oikarinen, Sami, Mazur, Magdalena A., Flodström-Tullberg, Malin, Dufour, Eric, Sioofy-Khojine, Amir-Babak, Hyöty, Heikki, Lahesmaa, Riitta

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Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells von Buchacher, Tanja, Honkimaa, Anni, Välikangas, Tommi, Lietzén, Niina, Hirvonen, M. Karoliina, Laiho, Jutta E., Sioofy-Khojine, Amir-Babak, Eskelinen, Eeva-Liisa, Hyöty, Heikki, Elo, Laura L., Lahesmaa, Riitta

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Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes von Krogvold, Lars, Edwin, Bjørn, Buanes, Trond, Frisk, Gun, Skog, Oskar, Anagandula, Mahesh, Korsgren, Olle, Undlien, Dag, Eike, Morten C, Richardson, Sarah J, Leete, Pia, Morgan, Noel G, Oikarinen, Sami, Oikarinen, Maarit, Laiho, Jutta E, Hyöty, Heikki, Ludvigsson, Johnny, Hanssen, Kristian F, Dahl-Jørgensen, Knut

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Detection of Viral -RNA and +RNA Strands in Enterovirus-Infected Cells and Tissues von Salmikangas, Sami, Laiho, Jutta E, Kalander, Kerttu, Laajala, Mira, Honkimaa, Anni, Shanina, Iryna, Oikarinen, Sami, Horwitz, Marc S, Hyöty, Heikki, Marjomäki, Varpu

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Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study von Oikarinen, Sami, Krogvold, Lars, Edwin, Bjørn, Buanes, Trond, Korsgren, Olle, Laiho, Jutta E., Oikarinen, Maarit, Ludvigsson, Johnny, Skog, Oskar, Anagandula, Mahesh, Frisk, Gun, Hyöty, Heikki, Dahl-Jørgensen, Knut

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Safety, tolerability and immunogenicity of PRV-101, a multivalent vaccine targeting coxsackie B viruses (CVBs) associated with type 1 diabetes: a double-blind randomised placebo-co... von Hyöty, Heikki, Kääriäinen, Susanna, Laiho, Jutta E., Comer, Gail M., Tian, Wei, Härkönen, Taina, Lehtonen, Jussi P., Oikarinen, Sami, Puustinen, Leena, Snyder, Michele, León, Francisco, Scheinin, Mika, Knip, Mikael, Sanjuan, Miguel

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Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection von Lin, Jake, Moradi, Elaheh, Salenius, Karoliina, Lehtipuro, Suvi, Häkkinen, Tomi, Laiho, Jutta E., Oikarinen, Sami, Randelin, Sofia, Parikh, Hemang M., Krischer, Jeffrey P., Toppari, Jorma, Lernmark, Åke, Petrosino, Joseph F., Ajami, Nadim J., She, Jin-Xiong, Hagopian, William A., Rewers, Marian J., Lloyd, Richard E., Rautajoki, Kirsi J., Hyöty, Heikki, Nykter, Matti

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Respiratory infections and type 1 diabetes: Potential roles in pathogenesis von Wu, Roy, Mumtaz, Mohsin, Maxwell, Anna J., Isaacs, Sonia R., Laiho, Jutta E., Rawlinson, William D., Hyöty, Heikki, Craig, Maria E., Kim, Ki Wook

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HLA‐DQ‐conferred risk for type 1 diabetes does not alter neutralizing antibody response to a widely used enterovirus vaccine, the poliovirus vaccine von Sioofy‐Khojine, Amir‐Babak, Lehtonen, Jussi P., Nurminen, Noora, Laiho, Jutta E., Toppari, Jorma, Veijola, Riitta, Lempainen, Johanna, Ilonen, Jorma, Knip, Mikael, Hyöty, Heikki

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Novel antivirals for severe enterovirus infection in immunocompromised hosts; A case series von Meinhardt, Andrea, Reilly, Liam, Kaliakatsos, Marios, Abdel-Aziz, Khaled, Alsharidah, Sondus, Bodi, Istvan, Booth, Claire, Chetty, Kritika, Evans, Jennifer, Ferreras-Antolín, Laura, Froude, Susannah, Galtrey, Clare M., Guruprasad, Suba, Hadden, Robert D., Hassell, Jane, Hyöty, Heikki, Kreins, Alexandra Y., Laiho, Jutta E., Lowe, David M., Lunn, Michael P., Mankad, Kshitij, Struik, Siske, Whittaker, Elizabeth, Worth, Austen, Yong, Patrick, Zhang, Liqun, Breuer, Judith, Kadambari, Seilesh

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Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes von Busse, Niels, Paroni, Federico, Richardson, Sarah J, Laiho, Jutta E, Oikarinen, Maarit, Frisk, Gun, Hyöty, Heikki, de Koning, Eelco, Morgan, Noel G, Maedler, Kathrin

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A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses von Saarinen, Niila V. V., Laiho, Jutta E., Richardson, Sarah J., Zeissler, Marie, Stone, Virginia M., Marjomäki, Varpu, Kantoluoto, Tino, Horwitz, Marc S., Sioofy-Khojine, Amirbabak, Honkimaa, Anni, Hankaniemi, Minna M., Flodström-Tullberg, Malin, Hyöty, Heikki, Hytönen, Vesa P., Laitinen, Olli H.

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Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas von Richardson, Sarah J., Leete, Pia, Dhayal, Shalinee, Russell, Mark A., Oikarinen, Maarit, Laiho, Jutta E., Svedin, Emma, Lind, Katharina, Rosenling, Therese, Chapman, Nora, Bone, Adrian J., Foulis, Alan K., Frisk, Gun, Flodstrom-Tullberg, Malin, Hober, Didier, Hyoty, Heikki, Morgan, Noel G.

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Relative sensitivity of immunohistochemistry, multiple reaction monitoring mass spectrometry, in situ hybridization and PCR to detect Coxsackievirus B1 in A549 cells von Laiho, Jutta E, Oikarinen, Maarit, Richardson, Sarah J, Frisk, Gun, Nyalwidhe, Julius, Burch, Tanya C, Morris, Margaret A, Oikarinen, Sami, Pugliese, Alberto, Dotta, Francesco, Campbell-Thompson, Martha, Nadler, Jerry, Morgan, Noel G, Hyöty, Heikki

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Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology von Laiho, Jutta E, Oikarinen, Sami, Oikarinen, Maarit, Larsson, Pär G, Stone, Virginia M, Hober, Didier, Oberste, Steven, Flodström-Tullberg, Malin, Isola, Jorma, Hyöty, Heikki

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Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter] von Richardson, Sarah J., Leete, Pia, Dhayal, Shalinee, Russell, Mark A., Oikarinen, Maarit, Laiho, Jutta E., Svedin, Emma, Lind, Katharina, Rosenling, Therese, Chapman, Nora, Bone, Adrian J., Foulis, Alan K., Frisk, Gun, Flodström-Tullberg, Malin, Hober, Didier, Hyoty, Heikki, Pugliese, Alberto, Morgan, Noel G.

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Detection of Viral -RNA and plus RNA Strands in Enterovirus-Infected Cells and Tissues von Salmikangas, Sami, Laiho, Jutta E., Kalander, Kerttu, Laajala, Mira, Honkimaa, Anni, Shanina, Iryna, Oikarinen, Sami, Horwitz, Marc S., Hyoty, Heikki, Marjomaki, Varpu

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Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes von Busse, Niels, Paroni, Federico, Richardson, Sarah J, Laiho, Jutta E, Oikarinen, Maarit, Frisk, Gun, Hyöty, Heikki, de Koning, Eelco, Morgan, Noel G, Maedler, Kathrin

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