Abstract 5053: Discovery of GDC-0810 a novel, non-steroidal selective estrogen receptor degrader with robust activity in pre-clinical models of endocrine-resistant breast cancer von Joseph, James, Govek, Steven, Darimont, Beatrice, Brigham, Daniel, Aparicio, Anna, Bischoff, Eric, Kahraman, Mehmet, Nannini, Michelle, Kaufman, Joshua, Lai, Andily, Lee, Kyoung-Jin, Oeh, Jason, Lu, Nhin, Zhou, Wei, Moon, Michael, Qian, Jing, Sensintaffar, John, Shao, Gang, Sampath, Deepak, Friedman, Lori S., Rix, Peter, Heyman, Richard A., Smith, Nicholas, Hager, Jeffrey H.

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composto e uso de um composto von KELLY G. SPRANKLE, MARK W. HOLLADAY, BRIAN T. CAMPBELL, EDUARDO SETTI, RAFFALELLA FARAONI, ANDILY G. LAI, MARTIN W. ROWBOTTON, QI CHAO, SUNNY ABRAHAM, SHRIPAD BHAGWAT

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