Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease von Rangaraju, Srikant, Dammer, Eric B, Raza, Syed Ali, Rathakrishnan, Priyadharshini, Xiao, Hailian, Gao, Tianwen, Duong, Duc M, Pennington, Michael W, Lah, James J, Seyfried, Nicholas T, Levey, Allan I

Volltext

Accelerated model-based T1, T2 and proton density mapping using a Bayesian approach with automatic hyperparameter estimation von Huang, Shuai, Lah, James J, Allen, Jason W, Qiu, Deqiang

Volltext

Robust quantitative susceptibility mapping via approximate message passing with parameter estimation von Huang, Shuai, Lah, James J., Allen, Jason W., Qiu, Deqiang

Volltext

Automated analysis of facial emotions in subjects with cognitive impairment von Jiang, Zifan, Seyedi, Salman, Haque, Rafi U, Pongos, Alvince L, Vickers, Kayci L, Manzanares, Cecelia M, Lah, James J, Levey, Allan I, Clifford, Gari D

Volltext

Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level von Johnson, Erik C. B., Carter, E. Kathleen, Dammer, Eric B., Duong, Duc M., Gerasimov, Ekaterina S., Liu, Yue, Liu, Jiaqi, Betarbet, Ranjita, Ping, Lingyan, Yin, Luming, Serrano, Geidy E., Beach, Thomas G., Peng, Junmin, De Jager, Philip L., Haroutunian, Vahram, Zhang, Bin, Gaiteri, Chris, Bennett, David A., Gearing, Marla, Wingo, Thomas S., Wingo, Aliza P., Lah, James J., Levey, Allan I., Seyfried, Nicholas T.

Volltext

Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age von Wingo, Aliza P., Dammer, Eric B., Breen, Michael S., Logsdon, Benjamin A., Duong, Duc M., Troncosco, Juan C., Thambisetty, Madhav, Beach, Thomas G., Serrano, Geidy E., Reiman, Eric M., Caselli, Richard J., Lah, James J., Seyfried, Nicholas T., Levey, Allan I., Wingo, Thomas S.

Volltext

A probabilistic Bayesian approach to recover R2$$ {R}_{2\ast } $$ map and phase images for quantitative susceptibility mapping von Huang, Shuai, Lah, James J., Allen, Jason W., Qiu, Deqiang

Volltext

Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease von Johnson, Erik C B, Dammer, Eric B, Duong, Duc M, Yin, Luming, Thambisetty, Madhav, Troncoso, Juan C, Lah, James J, Levey, Allan I, Seyfried, Nicholas T

Volltext

Brain proteome-wide association study implicates novel proteins in depression pathogenesis von Wingo, Thomas S., Liu, Yue, Gerasimov, Ekaterina S., Gockley, Jake, Logsdon, Benjamin A., Duong, Duc M., Dammer, Eric B., Lori, Adriana, Kim, Paul J., Ressler, Kerry J., Beach, Thomas G., Reiman, Eric M., Epstein, Michael P., De Jager, Philip L., Lah, James J., Bennett, David A., Seyfried, Nicholas T., Levey, Allan I., Wingo, Aliza P.

Volltext

Variant of TREM2 Associated with the Risk of Alzheimer's Disease von Jonsson, Thorlakur, Stefansson, Hreinn, Steinberg, Stacy, Jonsdottir, Ingileif, Jonsson, Palmi V, Snaedal, Jon, Bjornsson, Sigurbjorn, Huttenlocher, Johanna, Levey, Allan I, Lah, James J, Rujescu, Dan, Hampel, Harald, Giegling, Ina, Andreassen, Ole A, Engedal, Knut, Ulstein, Ingun, Djurovic, Srdjan, Ibrahim-Verbaas, Carla, Hofman, Albert, Ikram, M. Arfan, van Duijn, Cornelia M, Thorsteinsdottir, Unnur, Kong, Augustine, Stefansson, Kari

Volltext

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation von Johnson, Erik C. B., Dammer, Eric B., Duong, Duc M., Ping, Lingyan, Zhou, Maotian, Yin, Luming, Higginbotham, Lenora A., Guajardo, Andrew, White, Bartholomew, Troncoso, Juan C., Thambisetty, Madhav, Montine, Thomas J., Lee, Edward B., Trojanowski, John Q., Beach, Thomas G., Reiman, Eric M., Haroutunian, Vahram, Wang, Minghui, Schadt, Eric, Zhang, Bin, Dickson, Dennis W., Ertekin-Taner, Nilüfer, Golde, Todd E., Petyuk, Vladislav A., De Jager, Philip L., Bennett, David A., Wingo, Thomas S., Rangaraju, Srikant, Hajjar, Ihab, Shulman, Joshua M., Lah, James J., Levey, Allan I., Seyfried, Nicholas T.

Volltext

Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease von Hsieh, Yi-Chen, Guo, Caiwei, Yalamanchili, Hari K., Abreha, Measho, Al-Ouran, Rami, Li, Yarong, Dammer, Eric B., Lah, James J., Levey, Allan I., Bennett, David A., De Jager, Philip L., Seyfried, Nicholas T., Liu, Zhandong, Shulman, Joshua M.

Volltext

Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease pathogenesis von Wingo, Aliza P., Liu, Yue, Gerasimov, Ekaterina S., Gockley, Jake, Logsdon, Benjamin A., Duong, Duc M., Dammer, Eric B., Robins, Chloe, Beach, Thomas G., Reiman, Eric M., Epstein, Michael P., De Jager, Philip L., Lah, James J., Bennett, David A., Seyfried, Nicholas T., Levey, Allan I., Wingo, Thomas S.

Volltext

Telehealth equivalence of the Montreal cognitive assessment (MoCA): Results from the Emory healthy brain study (EHBS) von Loring, David W., Lah, James J., Goldstein, Felicia C.

Volltext

Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins von Rangaraju, Srikant, Dammer, Eric B, Raza, Syed Ali, Gao, Tianwen, Xiao, Hailian, Betarbet, Ranjita, Duong, Duc M, Webster, James A, Hales, Chadwick M, Lah, James J, Levey, Allan I, Seyfried, Nicholas T

Volltext

A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain von Umoh, Mfon E, Dammer, Eric B, Dai, Jingting, Duong, Duc M, Lah, James J, Levey, Allan I, Gearing, Marla, Glass, Jonathan D, Seyfried, Nicholas T

Volltext

The complex relationship of air pollution and neighborhood socioeconomic status and their association with cognitive decline von Christensen, Grace M., Li, Zhenjiang, Pearce, John, Marcus, Michele, Lah, James J., Waller, Lance A., Ebelt, Stefanie, Hüls, Anke

Volltext

Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease von Ping, Lingyan, Duong, Duc M., Yin, Luming, Gearing, Marla, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.

Volltext

Extracellular signal‐regulated kinase regulates microglial immune responses in Alzheimer’s disease von Chen, Michael J., Ramesha, Supriya, Weinstock, Laura D., Gao, Tianwen, Ping, Lingyan, Xiao, Hailian, Dammer, Eric B., Duong, Duc D., Levey, Allan I., Lah, James J., Seyfried, Nicholas T., Wood, Levi B., Rangaraju, Srikant

Volltext

A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease von Seyfried, Nicholas T., Dammer, Eric B., Swarup, Vivek, Nandakumar, Divya, Duong, Duc M., Yin, Luming, Deng, Qiudong, Nguyen, Tram, Hales, Chadwick M., Wingo, Thomas, Glass, Jonathan, Gearing, Marla, Thambisetty, Madhav, Troncoso, Juan C., Geschwind, Daniel H., Lah, James J., Levey, Allan I.

Volltext