Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide von van Nifterik, K A, van den Berg, J, van der Meide, W F, Ameziane, N, Wedekind, L E, Steenbergen, R D M, Leenstra, S, Lafleur, M V M, Slotman, B J, Stalpers, L J A, Sminia, P

Volltext

Characterization of DNA damage induced by gamma-radiationderived water radicals, using DNA repair enzymes von K. KUIPERS M. V. M. LAFLEUR, G.

Volltext

Influence of the antioxidant N-acetylcysteine and its metabolites on damage induced by bleomycin in PM2 bacteriophage DNA von Cloos, Jacqueline, Gille, Johan J.P., Steen, Ivar, Lafleur, M.Vincent, Retèl, Jan, Snow, Gordon B., Braakhuis, Boudewijn J.M.

Volltext

Biological consequences of DNA damage introduced in bacteriophage PM2 DNA by hydrogen peroxide-mediated free radical reactions von GILLE, J. J. P, WIENTJES, N. M, LAFLEUR, M. V. M, JOENJE, H, RETEL, J

Volltext

Cytochrome P-450-mediated O-demethylation: a route in the metabolic activation of etoposide (VP-16-213) von VAN MAANEN, J. M. S, DE VRIES, J, PAPPIE, D, VAN DEN AKKER, E, LAFLEUR, M. V. M, RETEL, J, VAN DER GREEF, J, PINEDO, H. M

Volltext

Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded ΦX174 DNA von Mans, DRA, Retèl, J, van Maanen, JMS, Lafleur, MVM, van Schaik, MA, Pinedo, HM, Lankelma, J

Volltext

Reactions of glutathione with the catechol, the ortho-quinone and the semi-quinone free radical of etoposide Consequences for DNA inactivation von Mans, D.R.A., Lafleur, M.V.M., Westmijze, E.J., Horn, I.R., Bets, D., Schuurhuis, G.J., Lankelma, J., Retèl, J.

Volltext

The role of prostaglandin H synthase-mediated metabolism in the induction of oxidative DNA damage by BHA metabolites von Schilderman, P.A.E.L., van Maanen, J.M.S., Vaarwerk, F.J.ten, Lafleur, M.V.M., Westmijze, E.J., Hoor, F. ten, Kleinjans, J.C.S.

Volltext

Abstracts von Roth, P., Silginer, M., Goodman, S. L., Hasenbach, K., Thies, S., Schraml, P., Tabatabai, G., Moch, H., Tritschler, I., Weller, M., Perin, A., Verginelli, F., Dali, R., Hei Man Fung, K., Lo, R., Longatti, P., Guiot, M., Del Maestro, R. F., Rossi, S., Di Porzio, U., Stechishin, O., Weiss, S., Stifani, S., Sanzey, M., Golebiewska, A., Stieber, D., Nazarov, P., Muller, A., Vallar, L., Niclou, S. P., Lawler, S. E., Chiocca, E., Williams, S. P., Wanka, C., Steinbach, J. P., Rieger, J., Lavon, I., Zrihan, D., Refael, M., Siegal, T., Sminia, P., Van Nifterik, K. A., Van den Berg, J., Lafleur, V. M., Stalpers, L. J. A., Slotman, B. J., Di stefano, A., Enciso-Mora, V., Marie, Y., Desestret, V., Labussiere, M., Idbaih, A., Hoang-Xuan, K., Delattre, J., Houlston, R., Sanson, M., Woehrer, A., Slavc, I., Stefanits, H., Waldhoer, T., Heinzl, H., Zielonke, N., Czech, T., Hainfellner, J. A., Haberler, C., Zouaoui, S., Darlix, A., Virion, J., Rigau, V., Mathieu-Daude, H., Bauchet, F., Figarella-Branger, D., Duffau, H., Taillandier, L., Bauchet, L., Naydenov, E., Popov, R., Tanova, R., Minkin, K., De Vleeschouwer, S., Van Gool, S., Cavaletti, G., Wilbers, J., Hoebers, F., Boogerd, W., van Werkhoven, E., Nowee, M., Hart, G., van Dijk, E., Kappelle, A., Dorresteijn, L., Furuse, M., Miyata, T., Yoritsune, E., Kawabata, S., Kuroiwa, T., Miyatake, S., Boele, F. W., Heimans, J. J., Aaronson, N. K.

Volltext

Contrasting effects of SH-compounds on oxidative DNA damage: repair and increase of damage von Lafleur, M.V.M., Retèl, J.

Volltext

Mutations induced by c-irradiation of M13 bacteriophages containing single-stranded DNA von E. F. BRAUN, E. J. WESTMIJZE, M. V. M. LAFLEUR AND J. RETEL, J.

Volltext

Role of oxidative DNA damage in the mechanism of fecapentaene 12 genotoxicity von de Kok, T.M.C.M., Pachen, D.M.F.A., van Maanen, J.M.S., Lafleur, M.V.M., Westmijze, E.J., Hoor, F.ten, Kleinjans, J.C.S.

Volltext

L-Dopa stimulates expression of the antioxidant enzyme NAD(P)H:quinone oxidoreductase (NQO) in cultured astroglial cells von van Muiswinkel, Freek L, Riemers, Frank M, Peters, Godefridus J, LaFleur, M.Vincent M, Siegel, David, Jongenelen, Cornelis A.M, Drukarch, Benjamin

Volltext

Single base mutations can be unequivocally and rapidly detected by analysis of DNA heteroduplexes, obtained with deletion-mutant instead of wild-type DNA von Akker, Eric van den, Braun, Jacqueline E.F., Pals, Gerard, Vincent, M., Lafleur, M., Retel, Jan

Volltext

Mutations induced by γ-irradiation of M13 bacteriophages containing single-stranded DNA von BRAUN, J. E. F, WESTMIJZE, E. J, LAFLEUR, M. V. M, RETEL, J

Volltext

Effects of the ortho-quinone and catechol of the antitumor drug VP-16-213 on the biological activity of single-stranded and double-stranded ΦX174 DNA von van Maanen, Johannes M.S., Lafleur, M.Vincent M., Mans, Dennis R.A., van den Akker, Eric, de Ruiter, Cor, Kootstra, Peter R., Pappie, David, de Vries, John, Retèl, Jan, Pinedo, Herbert M.

Volltext

Formation of different reaction products with single- and double-stranded DNA by the ortho-quinone and the semi-quinone free radical of etoposide (VP-16-213) von Mans, D.R.A., Lafleur, M.V.M., Westmijze, E.J., Van Maanen, J.M.S., Van Schaik, M.A., Lankelma, J., Retèl, J.

Volltext

DNA damage induced by reduced nitroimidazole drugs von Zahoor, A., Lafleur, M.V.M., Knight, R.C., Loman, H., Edwards, D.I.

Volltext

Singlet molecular oxygen causes loss of biological activity in plasmid and bacteriophage DNA and induces single-strand breaks von Di Mascio, Paolo, Wefers, Heribert, Do-Thi, Hong-Phuc, Lafleur, M. Vincent M., Sies, Helmust

Volltext

Characterization of DNA damage induced by gamma-radiation-derived water radicals, using DNA repair enzymes von KUIPERS, G. K, LAFLEUR, M. M

Volltext