Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine von Hansen, Scott G, Zak, Daniel E, Xu, Guangwu, Ford, Julia C, Marshall, Emily E, Malouli, Daniel, Gilbride, Roxanne M, Hughes, Colette M, Ventura, Abigail B, Ainslie, Emily, Randall, Kurt T, Selseth, Andrea N, Rundstrom, Parker, Herlache, Lauren, Lewis, Matthew S, Park, Haesun, Planer, Shannon L, Turner, John M, Fischer, Miranda, Armstrong, Christina, Zweig, Robert C, Valvo, Joseph, Braun, Jackie M, Shankar, Smitha, Lu, Lenette, Sylwester, Andrew W, Legasse, Alfred W, Messerle, Martin, Jarvis, Michael A, Amon, Lynn M, Aderem, Alan, Alter, Galit, Laddy, Dominick J, Stone, Michele, Bonavia, Aurelio, Evans, Thomas G, Axthelm, Michael K, Früh, Klaus, Edlefsen, Paul T, Picker, Louis J

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Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens von Laddy, Dominick J, Yan, Jian, Kutzler, Michele, Kobasa, Darwyn, Kobinger, Gary P, Khan, Amir S, Greenhouse, Jack, Sardesai, Niranjan Y, Draghia-Akli, Ruxandra, Weiner, David B

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Prevention of tuberculosis in macaques after intravenous BCG immunization von Darrah, Patricia A., Zeppa, Joseph J., Maiello, Pauline, Hackney, Joshua A., Wadsworth, Marc H., Hughes, Travis K., Pokkali, Supriya, Swanson, Phillip A., Grant, Nicole L., Rodgers, Mark A., Kamath, Megha, Causgrove, Chelsea M., Laddy, Dominick J., Bonavia, Aurelio, Casimiro, Danilo, Lin, Philana Ling, Klein, Edwin, White, Alexander G., Scanga, Charles A., Shalek, Alex K., Roederer, Mario, Flynn, JoAnne L., Seder, Robert A.

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Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype von Smith, Clare M, Proulx, Megan K, Olive, Andrew J, Laddy, Dominick, Mishra, Bibhuti B, Moss, Caitlin, Gutierrez, Nuria Martinez, Bellerose, Michelle M, Barreira-Silva, Palmira, Phuah, Jia Yao, Baker, Richard E, Behar, Samuel M, Kornfeld, Hardy, Evans, Thomas G, Beamer, Gillian, Sassetti, Christopher M

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Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity von Morrow, Matthew P., Pankhong, Panyupa, Laddy, Dominick J., Schoenly, Kimberly A., Yan, Jian, Cisper, Neil, Weiner, David B.

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Electroporation of Synthetic DNA Antigens Offers Protection in Nonhuman Primates Challenged with Highly Pathogenic Avian Influenza Virus von LADDY, Dominick J, JIAN YAN, DRAGHIA-AKLI, Ruxandra, WEINER, David B, KHAN, Amir S, ANDERSEN, Hanne, COHN, Amanda, GREENHOUSE, Jack, LEWIS, Mark, MANISCHEWITZ, Jody, KING, Lisa R, GOLDING, Hana

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MTBVAC vaccination protects rhesus macaques against aerosol challenge with M. tuberculosis and induces immune signatures analogous to those observed in clinical studies von White, Andrew D., Sibley, Laura, Sarfas, Charlotte, Morrison, Alexandra, Gullick, Jennie, Clark, Simon, Gleeson, Fergus, McIntyre, Anthony, Arlehamn, Cecilia Lindestam, Sette, Alessandro, Salguero, Francisco J., Rayner, Emma, Rodriguez, Esteban, Puentes, Eugenia, Laddy, Dominick, Williams, Ann, Dennis, Mike, Martin, Carlos, Sharpe, Sally

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The TB vaccine development pathway – An innovative approach to accelerating global TB vaccine development von Roordink, Danielle, Williams, Ann, Fritzell, Bernard, Laddy, Dominick J., Gerdil, Emmanuelle, Graffin, Anne Marie, Tait, Dereck, van der Pol, Leo, van den Brink, Ilona, Holleman, Marit, Thole, Jelle, Voss, Gerald, Lempicki, Maria, Thiry, Georges

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Toward Tuberculosis Vaccine Development: Recommendations for Nonhuman Primate Study Design von Laddy, Dominick J, Bonavia, Aurelio, Hanekom, Willem A, Kaushal, Deepak, Williams, Ann, Roederer, Mario, Seder, Robert A, Sharpe, Sally, Verreck, Frank A W, Darrah, Patricia A

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Immunogenicity and Protective Efficacy of the DAR-901 Booster Vaccine in a Murine Model of Tuberculosis von Lahey, Timothy, Laddy, Dominick, Hill, Krystal, Schaeffer, Jacqueline, Hogg, Alison, Keeble, James, Dagg, Belinda, Ho, Mei Mei, Arbeit, Robert D, von Reyn, C Fordham

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Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus von Muthumani, Karuppiah, Lankaraman, Katthikbabu M, Laddy, Dominick J, Sundaram, Senthil G, Chung, Christopher W, Sako, Eric, Wu, Ling, Khan, Amir, Sardesai, Niranjan, Kim, Joseph J, Vijayachari, Paluru, Weiner, David B

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From Plasmids to Protection: A Review of DNA Vaccines Against Infectious Diseases von Laddy, Dominick J., Weiner, David B.

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Immunogenicity of novel consensus-based DNA vaccines against avian influenza von Laddy, Dominick J, Yan, Jian, Corbitt, Natasha, Kobasa, Darwyn, Kobinger, Gary P, Weiner, David B

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Human Immunodeficiency Virus Type 1 Nef Induces Programmed Death 1 Expression through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism von MUTHUMANI, Karuppiah, CHOO, Andrew Y, TEBAS, Pablo, SILVESTRI, Guido, WEINER, David B, SHEDLOCK, Devon J, LADDY, Dominick J, SUNDARAM, Senthil G, HIRAO, Lauren, LING WU, THIEU, Khanh P, CHUNG, Christopher W, LANKARAMAN, Karthikbabu M

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Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques von Darrah, Patricia A., DiFazio, Robert M., Maiello, Pauline, Gideon, Hannah P., Myers, Amy J., Rodgers, Mark A., Hackney, Joshua A., Lindenstrom, Thomas, Evans, Thomas, Scanga, Charles A., Prikhodko, Victor, Andersen, Peter, Lin, Philana Ling, Laddy, Dominick, Roederer, Mario, Seder, Robert A., Flynn, JoAnne L.

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Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG von Villarreal, Daniel O, Walters, Jewell, Laddy, Dominick J, Yan, Jian, Weiner, David B

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Co-immunization with an optimized plasmid-encoded immune stimulatory interleukin, high-mobility group box 1 protein, results in enhanced interferon-γ secretion by antigen-specific... von Muthumani, Gowtham, Laddy, Dominick J, Sundaram, Senthil G, Fagone, Paolo, Shedlock, Devon J, Kannan, Senthil, Wu, Ling, Chung, Christopher W, Lankaraman, Karthikbabu Mallil, Burns, John, Muthumani, Karuppiah, Weiner, David B

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Plasmid-Encoded Interleukin-15 Receptor α Enhances Specific Immune Responses Induced by a DNA Vaccine In Vivo von KRAYNYAK, Kimberly A, KUTZLER, Michele A, CISPER, Neil J, LADDY, Dominick J, MORROW, Matthew P, WALDMANN, Thomas A, WEINER, David B

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High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model von Yin, Jiangmei, Dai, Anlan, Laddy, Dominick J, Yan, Jian, Arango, Tatiana, Khan, Amir S, Lewis, Mark G, Andersen, Hanne, Kutzler, Michele A, Draghia-Akli, Ruxandra, Weiner, David B, Boyer, Jean D

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Nonclinical Development of BCG Replacement Vaccine Candidates von Velmurugan, Kamalakannan, Grode, Leander, Chang, Rosemary, Fitzpatrick, Megan, Laddy, Dominick, Hokey, David, Derrick, Steven, Morris, Sheldon, McCown, David, Kidd, Reginald, Gengenbacher, Martin, Eisele, Bernd, Kaufmann, Stefan H E, Fulkerson, John, Brennan, Michael J

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