Investigating G protein signalling bias at the glucagon‐like peptide‐1 receptor in yeast von Weston, C, Poyner, D, Patel, V, Dowell, S, Ladds, G

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Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor von Bridge, L.J., Mead, J., Frattini, E., Winfield, I., Ladds, G.

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Combining native and ‘omics’ mass spectrometry to identify endogenous ligands bound to membrane proteins von Gault, Joseph, Liko, Idlir, Landreh, Michael, Shutin, Denis, Bolla, Jani Reddy, Jefferies, Damien, Agasid, Mark, Yen, Hsin-Yung, Ladds, Marcus J. G. W., Lane, David P., Khalid, Syma, Mullen, Christopher, Remes, Philip M., Huguet, Romain, McAlister, Graeme, Goodwin, Michael, Viner, Rosa, Syka, John E.P., Robinson, Carol V.

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Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib von Ladds, Marcus J G W, Pastor-Fernández, Andrés, Popova, Gergana, van Leeuwen, Ingeborg M M, Eng, Kai Er, Drummond, Catherine J, Johansson, Lars, Svensson, Richard, Westwood, Nicholas J, McCarthy, Anna R, Tholander, Fredrik, Popa, Mihaela, Lane, David P, McCormack, Emmet, McInerney, Gerald M, Bhatia, Ravi, Laín, Sonia

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Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability von Popova, Gergana, Ladds, Marcus J. G. W, Johansson, Lars, Saleh, Aljona, Larsson, Johanna, Sandberg, Lars, Sahlberg, Sara Häggblad, Qian, Weixing, Gullberg, Hjalmar, Garg, Neeraj, Gustavsson, Anna-Lena, Haraldsson, Martin, Lane, David, Yngve, Ulrika, Lain, Sonia

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ATG7 is a haploinsufficient repressor of tumor progression and promoter of metastasis von Long, Jaclyn S, Kania, Elżbieta, McEwan, David G, Barthet, Valentin J A, Brucoli, Martina, Ladds, Marcus J G W, Nössing, Christoph, Ryan, Kevin M

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Small molecule activators of the p53 response von Ladds, Marcus J G W, Laín, Sonia

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Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology von Ladds, Marcus J. G.W., Popova, Gergana, Pastor-Fernández, Andrés, Kannan, Srinivasaraghavan, van Leeuwen, Ingeborg M.M., Håkansson, Maria, Walse, Björn, Tholander, Fredrik, Bhatia, Ravi, Verma, Chandra S., Lane, David P., Laín, Sonia

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GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation von Shigeto, Makoto, Ramracheya, Reshma, Tarasov, Andrei I, Cha, Chae Young, Chibalina, Margarita V, Hastoy, Benoit, Philippaert, Koenraad, Reinbothe, Thomas, Rorsman, Nils, Salehi, Albert, Sones, William R, Vergari, Elisa, Weston, Cathryn, Gorelik, Julia, Katsura, Masashi, Nikolaev, Viacheslav O, Vennekens, Rudi, Zaccolo, Manuela, Galione, Antony, Johnson, Paul R V, Kaku, Kohei, Ladds, Graham, Rorsman, Patrik

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PO-086 BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous cell carcinoma von Lazarus, K, Hadi, F, Bach, K, Watson, J, Das, M, Ladds, G, Quesne, J Le, Lee, JH, Calado, D, Khaled, W

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Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase von Costeira-Paulo, Joana, Gault, Joseph, Popova, Gergana, Ladds, Marcus J.G.W., van Leeuwen, Ingeborg M.M., Sarr, Médoune, Olsson, Anders, Lane, David P., Laín, Sonia, Marklund, Erik G., Landreh, Michael

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Identification of proteases with shared functions to the proprotein processing protease Krp1 in the fission yeast Schizosaccharomyces pombe von Ladds, Graham, Davey, John

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Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage von Ladds, Marcus J. G. W., van Leeuwen, Ingeborg M. M., Drummond, Catherine J., Chu, Su, Healy, Alan R., Popova, Gergana, Fernández, Andrés Pastor, Mollick, Tanzina, Darekar, Suhas, Sedimbi, Saikiran K., Nekulova, Marta, Sachweh, Marijke C. C., Campbell, Johanna, Higgins, Maureen, Tuck, Chloe, Popa, Mihaela, Safont, Mireia Mayoral, Gelebart, Pascal, Fandalyuk, Zinayida, Thompson, Alastair M., Svensson, Richard, Gustavsson, Anna-Lena, Johansson, Lars, Färnegårdh, Katarina, Yngve, Ulrika, Saleh, Aljona, Haraldsson, Martin, D’Hollander, Agathe C. A., Franco, Marcela, Zhao, Yan, Håkansson, Maria, Walse, Björn, Larsson, Karin, Peat, Emma M., Pelechano, Vicent, Lunec, John, Vojtesek, Borivoj, Carmena, Mar, Earnshaw, William C., McCarthy, Anna R., Westwood, Nicholas J., Arsenian-Henriksson, Marie, Lane, David P., Bhatia, Ravi, McCormack, Emmet, Laín, Sonia

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Interaction of PLD1b with actin in antigen-stimulated mast cells von Farquhar, M.J., Powner, D.J., Levine, B.A., Wright, M.H., Ladds, G., Hodgkin, M.N.

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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver von Barthet, Valentin J A, Brucoli, Martina, Ladds, Marcus J G W, Nössing, Christoph, Kiourtis, Christos, Baudot, Alice D, O'Prey, James, Zunino, Barbara, Müller, Miryam, May, Stephanie, Nixon, Colin, Long, Jaclyn S, Bird, Thomas G, Ryan, Kevin M

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Engineering a model cell for rational tuning of GPCR signaling von Shaw, W, Yamauchi, H, Mead, J, Gowers, G, Bell, D, Oling, D, Larsson, N, Wigglesworth, M, Ladds, G, Ellis, T

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Tenovin-D3, a novel small-molecule inhibitor of sirtuin SirT2, increases p21 (CDKN1A) expression in a p53-independent manner von McCarthy, Anna R, Sachweh, Marijke C C, Higgins, Maureen, Campbell, Johanna, Drummond, Catherine J, van Leeuwen, Ingeborg M M, Pirrie, Lisa, Ladds, Marcus J G W, Westwood, Nicholas J, Laín, Sonia

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Structure-based identification of dual ligands at the A(2A)R and PDE10A with anti-proliferative effects in lung cancer cell-lines von Kalash, L, Winfield, I, Safitri, D, Bermudez, M, Carvalho, S, Glen, R, Ladds, G, Bender, A

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Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage von Ladds, Marcus J. G. W., van Leeuwen, Ingeborg M. M., Drummond, Catherine J., Chu, Su, Healy, Alan R., Popova, Gergana, Pastor Fernández, Andrés, Mollick, Tanzina, Darekar, Suhas, Sedimbi, Saikiran K., Nekulova, Marta, Sachweh, Marijke C. C., Campbell, Johanna, Higgins, Maureen, Tuck, Chloe, Popa, Mihaela, Safont, Mireia Mayoral, Gelebart, Pascal, Fandalyuk, Zinayida, Thompson, Alastair M., Svensson, Richard, Gustavsson, Anna-Lena, Johansson, Lars, Färnegårdh, Katarina, Yngve, Ulrika, Saleh, Aljona, Haraldsson, Martin, D’Hollander, Agathe C. A., Franco, Marcela, Zhao, Yan, Håkansson, Maria, Walse, Björn, Larsson, Karin, Peat, Emma M., Pelechano, Vicent, Lunec, John, Vojtesek, Borivoj, Carmena, Mar, Earnshaw, William C., McCarthy, Anna R., Westwood, Nicholas J., Arsenian-Henriksson, Marie, Lane, David P., Bhatia, Ravi, McCormack, Emmet, Laín, Sonia

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Functional analysis of heterologous GPCR signalling pathways in yeast von Ladds, Graham, Goddard, Alan, Davey, John

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