The role of toxins in Clostridium difficile infection von Chandrasekaran, Ramyavardhanee, Lacy, D. Borden

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Clostridioides difficile toxins: mechanisms of action and antitoxin therapeutics von Kordus, Shannon L., Thomas, Audrey K., Lacy, D. Borden

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Molecular architecture of bacterial type IV secretion systems von Sheedlo, Michael J, Ohi, Melanie D, Lacy, D Borden, Cover, Timothy L

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Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection von Peritore-Galve, F Christopher, Shupe, John A, Cave, Rory J, Childress, Kevin O, Washington, M Kay, Kuehne, Sarah A, Lacy, D Borden

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Staphylococcus aureus Leukotoxin ED Targets the Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection von Reyes-Robles, Tamara, Alonzo, Francis, Kozhaya, Lina, Lacy, D. Borden, Unutmaz, Derya, Torres, Victor J.

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Paeniclostridium sordellii uterine infection is dependent on the estrous cycle von Bernard, Sarah C, Washington, M Kay, Lacy, D Borden

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Intestinal bile acids directly modulate the structure and function of C. difficile TcdB toxin von Tam, John, Icho, Simoun, Utama, Evelyn, Orrell, Kathleen E., Gómez-Biagi, Rodolfo F., Theriot, Casey M., Kroh, Heather K., Rutherford, Stacey A., Lacy, D. Borden, Melnyk, Roman A.

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Structural elucidation of the Clostridioides difficile transferase toxin reveals a single-site binding mode for the enzyme von Sheedlo, Michael J., Anderson, David M., Thomas, Audrey K., Lacy, D. Borden

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Identification of an epithelial cell receptor responsible for Clostridium difficile TcdB-induced cytotoxicity von LaFrance, Michelle E, Farrow, Melissa A, Chandrasekaran, Ramyavardhanee, Sheng, Jinsong, Rubin, Donald H, Lacy, D Borden

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Nanobodies against C. difficile TcdA and TcdB reveal unexpected neutralizing epitopes and provide a toolkit for toxin quantitation in vivo von Kordus, Shannon L, Kroh, Heather K, Rodríguez, Rubén Cano, Shrem, Rebecca A, Peritore-Galve, F Christopher, Shupe, John A, Wadzinski, Brian E, Lacy, D Borden, Spiller, Benjamin W

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Cloning and variation of ground state intestinal stem cells von Wang, Xia, Yamamoto, Yusuke, Wilson, Lane H., Zhang, Ting, Howitt, Brooke E., Farrow, Melissa A., Kern, Florian, Ning, Gang, Hong, Yue, Khor, Chiea Chuen, Chevalier, Benoit, Bertrand, Denis, Wu, Lingyan, Nagarajan, Niranjan, Sylvester, Francisco A., Hyams, Jeffrey S., Devers, Thomas, Bronson, Roderick, Lacy, D. Borden, Ho, Khek Yu, Crum, Christopher P., McKeon, Frank, Xian, Wa

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Clostridium difficile Toxin A Undergoes Clathrin-Independent, PACSIN2-Dependent Endocytosis von Chandrasekaran, Ramyavardhanee, Kenworthy, Anne K, Lacy, D Borden

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Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex von Durie, Clarissa L., Sheedlo, Michael J., Chung, Jeong Min, Byrne, Brenda G., Su, Min, Knight, Thomas, Swanson, Michele, Lacy, D. Borden, Ohi, Melanie D.

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Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile inf... von Nabukhotna, Kateryna, Kordus, Shannon L, Shupe, John A, Cano Rodríguez, Rubén, Smith, Anna, Bohannon, Julia K, Washington, M Kay, Lacy, D Borden

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Toward a structural understanding of Clostridium difficile toxins A and B von Pruitt, Rory N, Lacy, D Borden

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Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex von Farrow, Melissa A., Chumbler, Nicole M., Lapierre, Lynne A., Franklin, Jeffrey L., Rutherford, Stacey A., Goldenring, James R., Lacy, D. Borden

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Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex von Sheedlo, Michael J., Chung, Jeong Min, Sawhney, Neha, Durie, Clarissa L., Cover, Timothy L., Ohi, Melanie D., Lacy, D. Borden

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Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB von Childress, Kevin O, Cencer, Caroline S, Tyska, Matthew J, Lacy, D Borden

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Murine Intrarectal Instillation of Purified Recombinant Clostridioides difficile Toxins Enables Mechanistic Studies of Pathogenesis von Markham, Nicholas O., Bloch, Sarah C., Shupe, John A., Laubacher, Erin N., Thomas, Audrey K., Kroh, Heather K., Childress, Kevin O., Peritore-Galve, F. Christopher, Washington, M. Kay, Coffey, Robert J., Lacy, D. Borden

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Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism von Chumbler, Nicole M, Farrow, Melissa A, Lapierre, Lynne A, Franklin, Jeffrey L, Haslam, David B, Haslam, David, Goldenring, James R, Lacy, D Borden

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