A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination von Wang, Anderson T., Kim, Taeho, Wagner, John E., Conti, Brooke A., Lach, Francis P., Huang, Athena L., Molina, Henrik, Sanborn, Erica M., Zierhut, Heather, Cornes, Belinda K., Abhyankar, Avinash, Sougnez, Carrie, Gabriel, Stacey B., Auerbach, Arleen D., Kowalczykowski, Stephen C., Smogorzewska, Agata

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Mutations of the SLX4 gene in Fanconi anemia von Kim, Yonghwan, Lach, Francis P, Desetty, Rohini, Hanenberg, Helmut, Auerbach, Arleen D, Smogorzewska, Agata

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Human GEN1 and the SLX4-Associated Nucleases MUS81 and SLX1 Are Essential for the Resolution of Replication-Induced Holliday Junctions von Garner, Elizabeth, Kim, Yonghwan, Lach, Francis P., Kottemann, Molly C., Smogorzewska, Agata

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Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links von Rickman, Kimberly A, Noonan, Raymond J, Lach, Francis P, Sridhar, Sunandini, Wang, Anderson T, Abhyankar, Avinash, Huang, Athena, Kelly, Michael, Auerbach, Arleen D, Smogorzewska, Agata

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Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4 von Kim, Yonghwan, Spitz, Gabriella S., Veturi, Uma, Lach, Francis P., Auerbach, Arleen D., Smogorzewska, Agata

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Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia von Rickman, Kimberly A., Lach, Francis P., Abhyankar, Avinash, Donovan, Frank X., Sanborn, Erica M., Kennedy, Jennifer A., Sougnez, Carrie, Gabriel, Stacey B., Elemento, Olivier, Chandrasekharappa, Settara C., Schindler, Detlev, Auerbach, Arleen D., Smogorzewska, Agata

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A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair von Smogorzewska, Agata, Desetty, Rohini, Saito, Takamune T., Schlabach, Michael, Lach, Francis P., Sowa, Mathew E., Clark, Alan B., Kunkel, Thomas A., Harper, J. Wade, Colaiácovo, Monica P., Elledge, Stephen J.

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RTF2 controls replication repriming and ribonucleotide excision at the replisome von Conti, Brooke A., Ruiz, Penelope D., Broton, Cayla, Blobel, Nicolas J., Kottemann, Molly C., Sridhar, Sunandini, Lach, Francis P., Wiley, Tom F., Sasi, Nanda K., Carroll, Thomas, Smogorzewska, Agata

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Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer von Reid, Sarah, Schindler, Detlev, Hanenberg, Helmut, Barker, Karen, Hanks, Sandra, Kalb, Reinhard, Neveling, Kornelia, Kelly, Patrick, Seal, Sheila, Freund, Marcel, Wurm, Melanie, Batish, Sat Dev, Lach, Francis P, Yetgin, Sevgi, Neitzel, Heidemarie, Ariffin, Hany, Tischkowitz, Marc, Mathew, Christopher G, Auerbach, Arleen D, Rahman, Nazneen

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Transcriptional Silencing of ALDH2 Confers a Dependency on Fanconi Anemia Proteins in Acute Myeloid Leukemia von Yang, Zhaolin, Wu, Xiaoli S, Wei, Yiliang, Polyanskaya, Sofya A, Iyer, Shruti V, Jung, Moonjung, Lach, Francis P, Adelman, Emmalee R, Klingbeil, Olaf, Milazzo, Joseph P, Kramer, Melissa, Demerdash, Osama E, Chang, Kenneth, Goodwin, Sara, Hodges, Emily, McCombie, W Richard, Figueroa, Maria E, Smogorzewska, Agata, Vakoc, Christopher R

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Massively parallel sequencing, aCGH, and RNA-Seq technologies provide a comprehensive molecular diagnosis of Fanconi anemia von Chandrasekharappa, Settara C., Lach, Francis P., Kimble, Danielle C., Kamat, Aparna, Teer, Jamie K., Donovan, Frank X., Flynn, Elizabeth, Sen, Shurjo K., Thongthip, Supawat, Sanborn, Erica, Smogorzewska, Agata, Auerbach, Arleen D., Ostrander, Elaine A., NISC Comparative Sequencing Program

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Origin, functional role, and clinical impact of Fanconi anemia FANCA mutations von Castella, Maria, Pujol, Roser, Callén, Elsa, Trujillo, Juan P., Casado, José A., Gille, Hans, Lach, Francis P., Auerbach, Arleen D., Schindler, Detlev, Benítez, Javier, Porto, Beatriz, Ferro, Teresa, Muñoz, Arturo, Sevilla, Julián, Madero, Luis, Cela, Elena, Beléndez, Cristina, de Heredia, Cristina Díaz, Olivé, Teresa, de Toledo, José Sánchez, Badell, Isabel, Torrent, Montserrat, Estella, Jesús, Dasí, Ángeles, Rodríguez-Villa, Antonia, Gómez, Pedro, Barbot, José, Tapia, María, Molinés, Antonio, Figuera, Ángela, Bueren, Juan A., Surrallés, Jordi

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A homozygous missense variant in UBE2T is associated with a mild Fanconi anemia phenotype von Schultz-Rogers, Laura, Lach, Francis P, Rickman, Kimberly A, Ferrer, Alejandro, Mangaonkar, Abhishek A, Schwab, Tanya L, Schmitz, Christopher T, Clark, Karl J, Dsouza, Nikita R, Zimmermann, Michael T, Litzow, Mark, Jacobi, Nicole, Klee, Eric W, Smogorzewska, Agata, Patnaik, Mrinal M

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Assessment of SLX4 Mutations in Hereditary Breast Cancers von Shah, Sohela, Kim, Yonghwan, Ostrovnaya, Irina, Murali, Rajmohan, Schrader, Kasmintan A, Lach, Francis P, Sarrel, Kara, Rau-Murthy, Rohini, Hansen, Nichole, Zhang, Liyng, Kirchhoff, Tomas, Stadler, Zsofia, Robson, Mark, Vijai, Joseph, Offit, Kenneth, Smogorzewska, Agata

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Comprehensive Analysis of Pathogenic Deletion Variants in Fanconi Anemia Genes von Flynn, Elizabeth K., Kamat, Aparna, Lach, Francis P., Donovan, Frank X., Kimble, Danielle C., Narisu, Narisu, Sanborn, Erica, Boulad, Farid, Davies, Stella M., Gillio III, Alfred P., Harris, Richard E., MacMillan, Margaret L., Wagner, John E., Smogorzewska, Agata, Auerbach, Arleen D., Ostrander, Elaine A., Chandrasekharappa, Settara C.

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Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity von Kottemann, Molly C., Conti, Brooke A., Lach, Francis P., Smogorzewska, Agata

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The structure-specific endonuclease complex SLX4–XPF regulates Tus–Ter-induced homologous recombination von Elango, Rajula, Panday, Arvind, Lach, Francis P., Willis, Nicholas A., Nicholson, Kaitlin, Duffey, Erin E., Smogorzewska, Agata, Scully, Ralph

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Suppression of non-homologous end joining does not rescue DNA repair defects in Fanconi anemia patient cells von Thongthip, Supawat, Conti, Brooke A., Lach, Francis P., Smogorzewska, Agata

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Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer von Webster, Andrew L. H., Sanders, Mathijs A., Patel, Krupa, Dietrich, Ralf, Noonan, Raymond J., Lach, Francis P., White, Ryan R., Goldfarb, Audrey, Hadi, Kevin, Edwards, Matthew M., Donovan, Frank X., Hoogenboezem, Remco M., Jung, Moonjung, Sridhar, Sunandini, Wiley, Tom F., Fedrigo, Olivier, Tian, Huasong, Rosiene, Joel, Heineman, Thomas, Kennedy, Jennifer A., Bean, Lorenzo, Rosti, Rasim O., Tryon, Rebecca, Gonzalez, Ashlyn-Maree, Rosenberg, Allana, Luo, Ji-Dung, Carroll, Thomas S., Shroff, Sanjana, Beaumont, Michael, Velleuer, Eunike, Rastatter, Jeff C., Wells, Susanne I., Surrallés, Jordi, Bagby, Grover, MacMillan, Margaret L., Wagner, John E., Cancio, Maria, Boulad, Farid, Scognamiglio, Theresa, Vaughan, Roger, Beaumont, Kristin G., Koren, Amnon, Imielinski, Marcin, Chandrasekharappa, Settara C., Auerbach, Arleen D., Singh, Bhuvanesh, Kutler, David I., Campbell, Peter J., Smogorzewska, Agata

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Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency von Cottineau, Julien, Kottemann, Molly C, Lach, Francis P, Kang, Young-Hoon, Vély, Frédéric, Deenick, Elissa K, Lazarov, Tomi, Gineau, Laure, Wang, Yi, Farina, Andrea, Chansel, Marie, Lorenzo, Lazaro, Piperoglou, Christelle, Ma, Cindy S, Nitschke, Patrick, Belkadi, Aziz, Itan, Yuval, Boisson, Bertrand, Jabot-Hanin, Fabienne, Picard, Capucine, Bustamante, Jacinta, Eidenschenk, Céline, Boucherit, Soraya, Aladjidi, Nathalie, Lacombe, Didier, Barat, Pascal, Qasim, Waseem, Hurst, Jane A, Pollard, Andrew J, Uhlig, Holm H, Fieschi, Claire, Michon, Jean, Bermudez, Vladimir P, Abel, Laurent, de Villartay, Jean-Pierre, Geissmann, Frédéric, Tangye, Stuart G, Hurwitz, Jerard, Vivier, Eric, Casanova, Jean-Laurent, Smogorzewska, Agata, Jouanguy, Emmanuelle

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