Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab von Lacey, David L., Boyle, William J., Simonet, W. Scott, Kostenuik, Paul J., Dougall, William C., Sullivan, John K., Martin, Javier San, Dansey, Roger

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Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival von Zhou, Xiaolan, Wang, Jin Lin, Lu, John, Song, Yanping, Kwak, Keith S., Jiao, Qingsheng, Rosenfeld, Robert, Chen, Qing, Boone, Thomas, Simonet, W. Scott, Lacey, David L., Goldberg, Alfred L., Han, H.Q.

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Osteoclast differentiation and activation von Boyle, William J, Simonet, W. Scott, Lacey, David L

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Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis von Li, Xiaodong, Ominsky, Michael S, Warmington, Kelly S, Morony, Sean, Gong, Jianhua, Cao, Jin, Gao, Yongming, Shalhoub, Victoria, Tipton, Barbara, Haldankar, Raj, Chen, Qing, Winters, Aaron, Boone, Tom, Geng, Zhaopo, Niu, Qing‐Tian, Ke, Hua Zhu, Kostenuik, Paul J, Simonet, W Scott, Lacey, David L, Paszty, Chris

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Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength von Li, Xiaodong, Ominsky, Michael S, Niu, Qing‐Tian, Sun, Ning, Daugherty, Betsy, D'Agostin, Diane, Kurahara, Carole, Gao, Yongming, Cao, Jin, Gong, Jianhua, Asuncion, Frank, Barrero, Mauricio, Warmington, Kelly, Dwyer, Denise, Stolina, Marina, Morony, Sean, Sarosi, Ildiko, Kostenuik, Paul J, Lacey, David L, Simonet, W Scott, Ke, Hua Zhu, Paszty, Chris

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Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones von Ominsky, Michael S, Li, Chaoyang, Li, Xiaodong, Tan, Hong L, Lee, Edward, Barrero, Mauricio, Asuncion, Franklin J, Dwyer, Denise, Han, Chun‐Ya, Vlasseros, Fay, Samadfam, Rana, Jolette, Jacquelin, Smith, Susan Y, Stolina, Marina, Lacey, David L, Simonet, William S, Paszty, Chris, Li, Gang, Ke, Hua Z

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Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength von Ominsky, Michael S, Vlasseros, Fay, Jolette, Jacquelin, Smith, Susan Y, Stouch, Brian, Doellgast, George, Gong, Jianhua, Gao, Yongming, Cao, Jin, Graham, Kevin, Tipton, Barbara, Cai, Jill, Deshpande, Rohini, Zhou, Lei, Hale, Michael D, Lightwood, Daniel J, Henry, Alistair J, Popplewell, Andrew G, Moore, Adrian R, Robinson, Martyn K, Lacey, David L, Simonet, W Scott, Paszty, Chris

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Role of RANK ligand in mediating increased bone resorption in early postmenopausal women von Eghbali-Fatourechi, Guitty, Khosla, Sundeep, Sanyal, Arunik, Boyle, William J, Lacey, David L, Riggs, B Lawrence

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Osteoprotegerin is an effective countermeasure for spaceflight-induced bone loss in mice von Lloyd, Shane A, Morony, Sean E, Ferguson, Virginia L, Simske, Steven J, Stodieck, Louis S, Warmington, Kelly S, Livingston, Eric W, Lacey, David L, Kostenuik, Paul J, Bateman, Ted A

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Effects of spaceflight on murine skeletal muscle gene expression von Allen, David L, Bandstra, Eric R, Harrison, Brooke C, Thorng, Seiha, Stodieck, Louis S, Kostenuik, Paul J, Morony, Sean, Lacey, David L, Hammond, Timothy G, Leinwand, Leslie L, Argraves, W. Scott, Bateman, Ted A, Barth, Jeremy L

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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis von Penninger, Josef M, Kong, Young-Yun, Yoshida, Hiroki, Sarosi, Ildiko, Tan, Hong-Lin, Timms, Emma, Capparelli, Casey, Morony, Sean, Oliveira-dos-Santos, Antonio J, Van, Gwyneth, Itie, Annick, Khoo, Wilson, Wakeham, Andrew, Dunstan, Colin R, Lacey, David L, Mak, Tak W, Boyle, William J

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Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia von Li, Ji, Sarosi, Ildiko, Cattley, Russell C., Pretorius, James, Asuncion, Frank, Grisanti, Mario, Morony, Sean, Adamu, Stephen, Geng, Zhaopo, Qiu, Wanrong, Kostenuik, Paul, Lacey, David L., Simonet, W. Scott, Bolon, Brad, Qian, Xueming, Shalhoub, Victoria, Ominsky, Michael S., Zhu Ke, Hua, Li, Xiaodong, Richards, William G.

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The Osteoclast Differentiation Factor Osteoprotegerin-Ligand Is Essential for Mammary Gland Development von Fata, Jimmie E, Kong, Young-Yun, Li, Ji, Sasaki, Takehiko, Irie-Sasaki, Junko, Moorehead, Roger A, Elliott, Robin, Scully, Sheila, Voura, Evelyn B, Lacey, David L, Boyle, William J, Khokha, Rama, Penninger, Josef M

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Identity management in disaster response environments: A child exploitation mitigation perspective von Allan, Kathryn, Lacey, David

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Tumor Necrosis Factor Receptor Family Member RANK Mediates Osteoclast Differentiation and Activation Induced by Osteoprotegerin Ligand von Hsu, Hailing, Lacey, David L., Dunstan, Colin R., Solovyev, Irina, Colombero, Anne, Timms, Emma, Tan, Hong-Lin, Elliott, Gary, Kelley, Michael J., Sarosi, Ildiko, Wang, Ling, Xia, Xing-Zhong, Elliott, Robin, Chiu, Laura, Black, Tabitha, Scully, Sheila, Capparelli, Casey, Morony, Sean, Shimamoto, Grant, Bass, Michael B., Boyle, William J.

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Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism von Colloton, Matthew, Shatzen, Edward, Miller, Gerald, Stehman-Breen, Catherine, Wada, Michihito, Lacey, David, Martin, David

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Does Job Training Work?: The Clients Speak Out von Ginzberg, Eli, Williams, Terry, Dutka, Anna, Lacey, David

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Exploiting organisational vulnerabilities as dark knowledge: conceptual development from organisational fraud cases von Goode, Sigi, Lacey, David

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Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand von Penninger, Josef M, Kong, Young-Yun, Feige, Ulrich, Sarosi, Iidiko, Bolon, Brad, Tafuri, Anna, Morony, Sean, Capparelli, Casey, Li, Ji, Elliott, Robin, McCabe, Susan, Wong, Thomas, Campagnuolo, Giuseppe, Moran, Erika, Bogoch, Earl R, Van, Gwyneth, Nguyen, Linh T, Ohashi, Pamela S, Lacey, David L, Fish, Eleanor, Boyle, William J

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Estrogen Stimulates Gene Expression and Protein Production of Osteoprotegerin in Human Osteoblastic Cells von Hofbauer, Lorenz C, Khosla, Sundeep, Dunstan, Colin R, Lacey, David L, Spelsberg, Thomas C, Riggs, B. Lawrence

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