Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes von Labib, Sarah, Williams, Andrew, Yauk, Carole L, Nikota, Jake K, Wallin, Håkan, Vogel, Ulla, Halappanavar, Sabina

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Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells von Søs Poulsen, Sarah, Jacobsen, Nicklas R, Labib, Sarah, Wu, Dongmei, Husain, Mainul, Williams, Andrew, Bøgelund, Jesper P, Andersen, Ole, Købler, Carsten, Mølhave, Kristian, Kyjovska, Zdenka O, Saber, Anne T, Wallin, Håkan, Yauk, Carole L, Vogel, Ulla, Halappanavar, Sabina

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A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects von Acosta-Uribe, Juliana, Aguillón, David, Cochran, J Nicholas, Giraldo, Margarita, Madrigal, Lucía, Killingsworth, Bradley W, Singhal, Rijul, Labib, Sarah, Alzate, Diana, Velilla, Lina, Moreno, Sonia, García, Gloria P, Saldarriaga, Amanda, Piedrahita, Francisco, Hincapié, Liliana, López, Hugo E, Perumal, Nithesh, Morelo, Leonilde, Vallejo, Dionis, Solano, Juan Marcos, Reiman, Eric M, Surace, Ezequiel I, Itzcovich, Tatiana, Allegri, Ricardo, Sánchez-Valle, Raquel, Villegas-Lanau, Andrés, White, 3rd, Charles L, Matallana, Diana, Myers, Richard M, Browning, Sharon R, Lopera, Francisco, Kosik, Kenneth S

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Lamin A/C mutants disturb sumo1 localization and sumoylation in vitro and in vivo von Boudreau, Émilie, Labib, Sarah, Bertrand, Anne T, Decostre, Valérie, Bolongo, Pierrette M, Sylvius, Nicolas, Bonne, Gisèle, Tesson, Frédérique

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Protein Kinase C Alpha Cellular Distribution, Activity, and Proximity with Lamin A/C in Striated Muscle Laminopathies von Nicolas, Hannah A., Bertrand, Anne T., Labib, Sarah, Mohamed-Uvaize, Musfira, Bolongo, Pierrette M., Wu, Wen Yu, Bilinska, Zofia T., Bonne, Gisele, Akimenko, Marie-Andree, Tesson, Frederique

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FORMULATION AND EVALUATION OF ATORVASTATIN CALCIUM NANOCRYSTALS CONTAINING P-GLYCOPROTEIN INHIBITORS FOR ENHANCING ORAL DELIVERY von LABIB, SARAH, NASR, MOHAMED

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End-tidal carbon dioxide measurements as a surrogate to arterial carbon dioxide during pediatric laparoscopic surgeries: a prospective observational cohort study von Abdel-Ghaffar, Hala Saad, Bakr, Mohammed Abdel-Moneim, Osman, Mohamed Abdel-Kadr, Hanna, Sarah George Labib, Ali, Wesam Nashat

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A new c.1621 C>G, p.R541G lamin A C mutation in a family with DCM and regional wall motion abnormalities (akinesis dyskinesis): genotype-phenotype correlation von Małek, Lukasz A, Labib, Sarah, Mazurkiewicz, Lukasz, Saj, Michał, Płoski, Rafał, Tesson, Frédérique, Bilińska, Zofia T

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Scalable new model of genomic care delivery: Assessing psychological outcomes von Gray, Stacy W., Solomon, Ilana, Labib, Sarah, Luong, Marilan, Garcia, Michael, Xiao, Yi, Bonner, Joseph D., Shaktah, Lawrence, Currey, Madeline, Fujii, Christina, Hampel, Heather, Hong, Christine, Idos, Gregory, McDonnell, Kevin, Lindsey, Sidney S., Park, Wai, Reyes, Kathryn, Tang, Sarah, Hamilton, Stanley R., Gruber, Stephen B.

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Healthcare utilization among individuals diagnosed with lynch syndrome through a universal germline genetic testing program von Hampel, Heather, Solomon, Ilana, Garcia, Michael, Luong, Marilan, Labib, Sarah, Bonner, Joseph D., Shaktah, Lawrence, Gima, Lauren, Hong, Christine, Idos, Gregory, Lindsey, Sidney S., McDonnell, Kevin, Park, Wai, Roth, Katherine G., Sobotka, Elise, Xiao, Yi, Hamilton, Stanley R., Gruber, Stephen B., Gray, Stacy W.

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Healthcare utilization among individuals diagnosed with hereditary breast-ovarian cancer syndrome through a universal germline genetic testing program von Gray, Stacy W., Hampel, Heather, Solomon, Ilana, Garcia, Michael, Luong, Marilan, Labib, Sarah, Bonner, Joseph D., Shaktah, Lawrence, Hong, Christine, Idos, Gregory, Lindsey, Sidney S., McDonnell, Kevin, Park, Wai, Roth, Katherine G., Sobotka, Elise, Xiao, Yi, Zukin, Elyssa, Hamilton, Stanley R., Gruber, Stephen B.

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A framework for the use of single-chemical transcriptomics data in predicting the hazards associated with complex mixtures of polycyclic aromatic hydrocarbons von Labib, Sarah, Williams, Andrew, Kuo, Byron, Yauk, Carole L., White, Paul A., Halappanavar, Sabina

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Toxicogenomic outcomes predictive of forestomach carcinogenesis following exposure to benzo(a)pyrene: Relevance to human cancer risk von Labib, Sarah, Guo, Charles H., Williams, Andrew, Yauk, Carole L., White, Paul A., Halappanavar, Sabina

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Subchronic oral exposure to benzo(a)pyrene leads to distinct transcriptomic changes in the lungs that are related to carcinogenesis von Labib, Sarah, Yauk, Carole, Williams, Andrew, Arlt, Volker M, Phillips, David H, White, Paul A, Halappanavar, Sabina

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A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects von Acosta Uribe, Juliana, Aguillón, David, Cochran, J. Nicholas, Giraldo, Margarita, Madrigal, Lucia, Killingsworth, Bradley W, Singhal, Rijul, Labib, Sarah, Alzate, Diana, Velilla, Lina, Moreno Escribà, Sonia, García, Gloria P, Saldarriaga, Amanda, Piedrahita, Francisco, Hincapié, Liliana, López, Hugo E, Perumal, Nithesh, Morelo, Leonilde, Vallejo, Dionis, Solano, Juan Marcos, Reiman, Eric M, Surace, Ezequiel I, Itzcovich, Tatiana, Allegri, Ricardo, Sánchez Valle, Raquel, Villegas Lanau, Andrés, White III, Charles L, Matallana, Diana, Myers, Richard M, Browning, Sharon R, Lopera, Francisco, Kosik, Kenneth S

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Genetic and ultrastructural studies in dilated cardiomyopathy patients: a large deletion in the lamin A/C gene is associated with cardiomyocyte nuclear envelope disruption von Gupta, Pallavi, Bilinska, Zofia T., Sylvius, Nicolas, Boudreau, Emilie, Veinot, John P., Labib, Sarah, Bolongo, Pierrette M., Hamza, Akil, Jackson, Tracy, Ploski, Rafal, Walski, Michal, Grzybowski, Jacek, Walczak, Ewa, Religa, Grzegorz, Fidzianska, Anna, Tesson, Frédérique

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Toxicogenomic applications in risk assessment at Health Canada von Yauk, Carole L., Cheung, Carmen, Barton-Maclaren, Tara S., Boucher, Sherri, Bourdon-Lacombe, Julie, Chauhan, Vinita, Gagné, Matthew, Gillespie, Zoe, Halappanavar, Sabina, Honeyman, Michael, Jones, Steven R., Jones-McLean, Elaine, Labib, Sarah, MacAulay, Jane, Moore, Jocelyn, Paquette, Martin, Petronella, Nicholas, Semalulu, Souleh, Slot, Andrew, Vespa, Alisa, Woodland, Cindy L.A.

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Utility of Toxicogenomics in Risk Assessment of Human Carcinogens: A Case Study on Benzo(a)pyrene von Chepelev, Nikolai L., Moffat, Ivy D., Labib, Sarah, Bourdon, Julie, Kuo, Byron, Buick, Julie, Lemieux, France, Malik, Amal, Halappanavar, Sabina, Yauk, Carole L.

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Variants of the Lamin A/C (LMNA) Gene in Non-Valvular Atrial Fibrillation Patients: A Possible Pathogenic Role of the Thr528Met Mutation von Saj, Michal, Dabrowski, Rafal, Labib, Sarah, Jankowska, Agnieszka, Szperl, Malgorzata, Broda, Grazyna, Szwed, Hanna, Tesson, Frederique, Bilinska, Zofia T., Ploski, Rafal

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Specific contribution of lamin A and lamin C in the development of laminopathies von Sylvius, Nicolas, Hathaway, Andrea, Boudreau, Emilie, Gupta, Pallavi, Labib, Sarah, Bolongo, Pierrette M., Rippstein, Peter, McBride, Heidi, Bilinska, Zofia T., Tesson, Frédérique

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