Discovery, synthesis and SAR of azinyl- and azolylbenzamides antagonists of the P2X7 receptor von Subramanyam, Chakrapani, Duplantier, Allen J., Dombroski, Mark A., Chang, Shang-Poa, Gabel, Christopher A., Whitney-Pickett, Carrie, Perregaux, David G., Labasi, Jeff M., Yoon, Kwansik, Shepard, Richard M., Fisher, Michael

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Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X₇ receptor antagonists leading to the discovery of the clinical candidate CE-224,53... von Duplantier, Allen J, Dombroski, Mark A, Subramanyam, Chakrapani, Beaulieu, Aimee M, Chang, Shang-Poa, Gabel, Christopher A, Jordan, Crystal, Kalgutkar, Amit S, Kraus, Kenneth G, Labasi, Jeff M, Mussari, Christopher, Perregaux, David G, Shepard, Rick, Taylor, Timothy J, Trevena, Kristen A, Whitney-Pickett, Carrie, Yoon, Kwansik

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Benzimidazolone p38 inhibitors von DOMBROSKI, Mark A, LETAVIC, Michael A, JORDAN, Crystal K, LABASI, Jeff M, MARTIN, William H, PEESE, Kevin M, STOCK, Ingrid A, SVENSSON, Linne, SWEENEY, Francis J, YU, Chul H, MCCLURE, Kim F, BARBERIA, John T, CARTY, Thomas J, CORTINA, Santo R, CSIKI, Csilla, DIPESA, Alan J, ELLIOTT, Nancy C, GABEL, Christopher A

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Structure–activity relationships of triazolopyridine oxazole p38 inhibitors: Identification of candidates for clinical development von McClure, Kim F., Letavic, Michael A., Kalgutkar, Amit S., Gabel, Christopher A., Audoly, Laurent, Barberia, John T., Braganza, John F., Carter, Demetrius, Carty, Thomas J., Cortina, Santo R., Dombroski, Mark A., Donahue, Kathleen M., Elliott, Nancy C., Gibbons, Colleen P., Jordan, Crystal K., Kuperman, Alexander V., Labasi, Jeff M., LaLiberte, Ronald E., McCoy, Jennifer M., Naiman, Brian M., Nelson, Kendra L., Nguyen, Hang T., Peese, Kevin M., Sweeney, Francis J., Taylor, Timothy J., Trebino, Catherine E., Abramov, Yuriy A., Laird, Ellen R., Volberg, Walter A., Zhou, Jun, Bach, Justin, Lombardo, Franco

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Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X 7 receptor antagonists leading to the discovery of the clinical candidate CE-224,5... von Duplantier, Allen J., Dombroski, Mark A., Subramanyam, Chakrapani, Beaulieu, Aimee M., Chang, Shang-Poa, Gabel, Christopher A., Jordan, Crystal, Kalgutkar, Amit S., Kraus, Kenneth G., Labasi, Jeff M., Mussari, Christopher, Perregaux, David G., Shepard, Rick, Taylor, Timothy J., Trevena, Kristen A., Whitney-Pickett, Carrie, Yoon, Kwansik

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Altered Cytokine Production in Mice Lacking P2X7Receptors von Solle, Mike, Labasi, Jeff, Perregaux, David G., Stam, Ethan, Petrushova, Nina, Koller, Beverly H., Griffiths, Richard J., Gabel, Christopher A.

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Discovery, synthesis and SAR of azinyl- and azolylbenzamides antagonists of the P2X sub(7 receptor) von Subramanyam, Chakrapani, Duplantier, Allen J, Dombroski, Mark A, Chang, Shang-Poa, Gabel, Christopher A, Whitney-Pickett, Carrie, Perregaux, David G, Labasi, Jeff M, Yoon, Kwansik, Shepard, Richard M, Fisher, Michael

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Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X sub(7 receptor antagonists leading to the discovery of the clinical candidate CE-2... von Duplantier, Allen J, Dombroski, Mark A, Subramanyam, Chakrapani, Beaulieu, Aimee M, Chang, Shang-Poa, Gabel, Christopher A, Jordan, Crystal, Kalgutkar, Amit S, Kraus, Kenneth G, Labasi, Jeff M, Mussari, Christopher, Perregaux, David G, Shepard, Rick, Taylor, Timothy J, Trevena, Kristen A, Whitney-Pickett, Carrie, Yoon, Kwansik

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Interleukin‐1β posttranslational processing—exploration of P2X 7 receptor involvement von Perregaux, David G., Labasi, Jeff, Laliberte, Ron, Stam, Ethan, Solle, Mike, Koller, Bev, Griffiths, Richard, Gabel, Christopher A.

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Interleukin-1β posttranslational processing-exploration of P2X7 receptor involvement von Perregaux, David G., Labasi, Jeff, Laliberte, Ron, Stam, Ethan, Solle, Mike, Koller, Bev, Griffiths, Richard, Gabel, Christopher A.

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