inhibitors of apoptosis (IAPs) as cancer targets von Hunter, Allison M, LaCasse, Eric C, Korneluk, Robert G

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Inhibitors of apoptosis (IAPs) regulate intestinal immunity and inflammatory bowel disease (IBD) inflammation von Pedersen, Jannie, LaCasse, Eric C, Seidelin, Jakob B, Coskun, Mehmet, Nielsen, Ole H

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Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma von Beug, Shawn T., Beauregard, Caroline E., Healy, Cristin, Sanda, Tarun, St-Jean, Martine, Chabot, Janelle, Walker, Danielle E., Mohan, Aditya, Earl, Nathalie, Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Staeheli, Peter, Forsyth, Peter A., Alain, Tommy, LaCasse, Eric C., Korneluk, Robert G.

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Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization von Morón-Calvente, Virginia, Romero-Pinedo, Salvador, Toribio-Castelló, Sofía, Plaza-Díaz, Julio, Abadía-Molina, Ana C, Rojas-Barros, Domingo I, Beug, Shawn T, LaCasse, Eric C, MacKenzie, Alex, Korneluk, Robert, Abadía-Molina, Francisco

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Astrocytes and the tumor microenvironment inflammatory state dictate the killing of glioblastoma cells by Smac mimetic compounds von Malone, Kyle, Dugas, Melanie, Earl, Nathalie, Alain, Tommy, LaCasse, Eric C., Beug, Shawn T.

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Smac mimetics and innate immune stimuli synergize to promote tumor death von Beug, Shawn T, Tang, Vera A, LaCasse, Eric C, Cheung, Herman H, Beauregard, Caroline E, Brun, Jan, Nuyens, Jeffrey P, Earl, Nathalie, St-Jean, Martine, Holbrook, Janelle, Dastidar, Himika, Mahoney, Douglas J, Ilkow, Carolina, Le Boeuf, Fabrice, Bell, John C, Korneluk, Robert G

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LCL161 enhances expansion and survival of engineered anti-tumor T cells but is restricted by death signaling von Afsahi, Arya, Silvestri, Christopher M, Moore, Allyson E, Graham, Carly F, Bacchiochi, Kaylyn, St-Jean, Martine, Baker, Christopher L, Korneluk, Robert G, Beug, Shawn T, LaCasse, Eric C, Bramson, Jonathan L

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Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy von Lala-Tabbert, Neena, Lejmi-Mrad, Rim, Timusk, Kristen, Fukano, Marina, Holbrook, Janelle, St-Jean, Martine, LaCasse, Eric C, Korneluk, Robert G

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Down-regulation of c-FLIP Enhances Death of Cancer Cells by Smac Mimetic Compound von CHEUNG, Herman H, MAHONEY, Douglas J, LACASSE, Eric C, KORNELUK, Robert G

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XIAP protection of photoreceptors in animal models of retinitis pigmentosa von Leonard, Kevin C, Petrin, Dino, Coupland, Stuart G, Baker, Adam N, Leonard, Brian C, LaCasse, Eric C, Hauswirth, William W, Korneluk, Robert G, Tsilfidis, Catherine

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Antisense Oligonucleotides Targeting XIAP Induce Apoptosis and Enhance Chemotherapeutic Activity against Human Lung Cancer Cells in Vitro and in Vivo von Hu, YanPing, Cherton-Horvat, Gabriele, Dragowska, Visia, Baird, Stephen, Korneluk, Robert G, Durkin, Jon P, Mayer, Lawrence D, LaCasse, Eric C

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Taking aim with IAP antagonists at triple-negative breast cancer: a moving target no more? von LaCasse, Eric C.

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Pulling the plug on a cancer cell by eliminating XIAP with AEG35156 von LaCasse, Eric C

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Preclinical Characterization of AEG35156/GEM 640, a Second-Generation Antisense Oligonucleotide Targeting X-Linked Inhibitor of Apoptosis von LACASSE, Eric C, CHERTON-HORVAT, Gabriele G, AGRAWAL, Sudhir, GILLARD, John W, DURKIN, Jon P, HEWITT, Kimberley E, JEROME, Lori J, MORRIS, Stephen J, KANDIMALLA, Ekambar R, DONG YU, HUI WANG, WEI WANG, RUIWEN ZHANG

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Selective JAK1 inhibitors for the treatment of inflammatory bowel disease von Nielsen, Ole Haagen, Boye, Theresa Louise, Gubatan, John, Chakravarti, Deepavali, Jaquith, James B., LaCasse, Eric C.

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Sp3-cificity of TNF-α expression promotes the Smac mimetic-mediated killing of cancer cells von Beug, Shawn T., Korneluk, Robert G., LaCasse, Eric C.

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Combination of IAP Antagonists and TNF-α-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression von Beug, Shawn T., Pichette, Stephanie J., St-Jean, Martine, Holbrook, Janelle, Walker, Danielle E., LaCasse, Eric C., Korneluk, Robert G.

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Modulation of immune signalling by inhibitors of apoptosis von Beug, Shawn T, Cheung, Herman H, LaCasse, Eric C, Korneluk, Robert G

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Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta von Micali, O Cristina, Cheung, Herman H, Plenchette, Stéphanie, Hurley, Sandra L, Liston, Peter, LaCasse, Eric C, Korneluk, Robert G

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The transcription factor SP3 drives TNF-α expression in response to Smac mimetics von Beug, Shawn T, Cheung, Herman H, Sanda, Tarun, St-Jean, Martine, Beauregard, Caroline E, Mamady, Hapsatou, Baird, Stephen D, LaCasse, Eric C, Korneluk, Robert G

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