The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study von Feng, Joy Y, Ly, John K, Myrick, Florence, Goodman, Derrick, White, Kirsten L, Svarovskaia, Evguenia S, Borroto-Esoda, Katyna, Miller, Michael D

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The K65R reverse transcriptase mutation in HIV-1 reverses the excision phenotype of zidovudine resistance mutations von WHITE, Kirsten L, CHEN, James M, FENG, Joy Y, MARGOT, Nicolas A, LY, John K, RAY, Adrian S, MACARTHUR, Holly L, MCDERMOTT, Martin J, SWAMINATHAN, S, MILLER, Michael D

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A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT von WHITE, Kirsten L, MARGOT, Nicolas A, LY, John K, CHEN, James M, RAY, Adrian S, PAVELKO, Martina, WANG, Ruth, MCDERMOTT, Martin, SWAMINATHAN, S, MILLER, Michael D

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Effects of the Translocation Status of Human Immunodeficiency Virus Type 1 Reverse Transcriptase on the Efficiency of Excision of Tenofovir von MARCHAND, Bruno, WHITE, Kirsten L, LY, John K, MARGOT, Nicolas A, WANG, Ruth, MCDERMOTT, Martin, MILLER, Michael D, GÖTTEL, Matthias

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The Balance between NRTI Discrimination and Excision Drives the Susceptibility of HIV-1 RT Mutants K65R, M184V and K65R+M184V von Ly, John K, Margot, Nicolas A, MacArthur, Holly L, Hung, Magdeleine, Miller, Michael D, White, Kirsten L

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The A62V and S68G Mutations in HIV-1 Reverse Transcriptase Partially Restore the Replication Defect Associated With the K65R Mutation von Svarovskaia, Evguenia S, Feng, Joy Y, Margot, Nicolas A, Myrick, Florence, Goodman, Derrick, Ly, John K, White, Kirsten L, Kutty, Nilima, Wang, Ruth, Borroto-Esoda, Katyna, Miller, Michael D

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A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19 von Lundgren, Jens D, Grund, Birgit, Barkauskas, Christina E, Holland, Thomas L, Gottlieb, Robert L, Sandkovsky, Uriel, Brown, Samuel M, Knowlton, Kirk U, Self, Wesley H, Files, D Clark, Jain, Mamta K, Benfield, Thomas, Bowdish, Michael E, Leshnower, Bradley G, Baker, Jason V, Jensen, Jens-Ulrik, Gardner, Edward M, Ginde, Adit A, Harris, Estelle S, Johansen, Isik S, Markowitz, Norman, Matthay, Michael A, Østergaard, Lars, Chang, Christina C, Davey, Victoria J, Goodman, Anna, Higgs, Elizabeth S, Murray, Daniel D, Murray, Thomas A, Paredes, Roger, Parmar, Mahesh K B, Phillips, Andrew N, Reilly, Cavan, Sharma, Shweta, Dewar, Robin L, Teitelbaum, Marc, Wentworth, Deborah, Cao, Huyen, Klekotka, Paul, Babiker, Abdel G, Gelijns, Annetine C, Kan, Virginia L, Polizzotto, Mark N, Thompson, B Taylor, Lane, H Clifford, Neaton, James D

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Dabigatran versus Warfarin in Patients with Atrial Fibrillation von Connolly, Stuart J, Ezekowitz, Michael D, Yusuf, Salim, Eikelboom, John, Oldgren, Jonas, Parekh, Amit, Pogue, Janice, Reilly, Paul A, Themeles, Ellison, Varrone, Jeanne, Wang, Susan, Alings, Marco, Xavier, Denis, Zhu, Jun, Diaz, Rafael, Lewis, Basil S, Darius, Harald, Diener, Hans-Christoph, Joyner, Campbell D, Wallentin, Lars

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Pharmacodynamics of mutant-IDH1 inhibitors in glioma patients probed by in vivo 3D MRS imaging of 2-hydroxyglutarate von Andronesi, Ovidiu C., Arrillaga-Romany, Isabel C., Ly, K. Ina, Bogner, Wolfgang, Ratai, Eva M., Reitz, Kara, Iafrate, A. John, Dietrich, Jorg, Gerstner, Elizabeth R., Chi, Andrew S., Rosen, Bruce R., Wen, Patrick Y., Cahill, Daniel P., Batchelor, Tracy T.

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FDA Approval Summary: Margetuximab plus Chemotherapy for Advanced or Metastatic HER2-Positive Breast Cancer von Royce, Melanie, Osgood, Christy L, Amatya, Anup K, Fiero, Mallorie H, Chang, C J George, Ricks, Tiffany K, Shetty, Krithika A, Kraft, Jeffrey, Qiu, Junshan, Song, Pengfei, Charlab, Rosane, Yu, Jingyu, King, Kathryn E, Rastogi, Anshu, Janelsins, Brian, Weinberg, Wendy C, Clouse, Kathleen, Borders-Hemphill, Vicky, Brown, Lindsey, Gomez-Broughton, Candace, Li, Zhong, Nguyen, Thuy Thanh, Qiu, Zhihao, Ly, Anh-Thy, Chang, Suyoung, Gao, Tingting, Tu, Chi-Ming, King-Kallimanis, Bellinda, Pierce, William F, Chiang, Kelly, Lee, Clara, Goldberg, Kirsten B, Leighton, John K, Tang, Shenghui, Pazdur, Richard, Beaver, Julia A, Amiri-Kordestani, Laleh

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Chromosomal instability drives metastasis through a cytosolic DNA response von Bakhoum, Samuel F., Ngo, Bryan, Laughney, Ashley M., Cavallo, Julie-Ann, Murphy, Charles J., Ly, Peter, Shah, Pragya, Sriram, Roshan K., Watkins, Thomas B. K., Taunk, Neil K., Duran, Mercedes, Pauli, Chantal, Shaw, Christine, Chadalavada, Kalyani, Rajasekhar, Vinagolu K., Genovese, Giulio, Venkatesan, Subramanian, Birkbak, Nicolai J., McGranahan, Nicholas, Lundquist, Mark, LaPlant, Quincey, Healey, John H., Elemento, Olivier, Chung, Christine H., Lee, Nancy Y., Imielenski, Marcin, Nanjangud, Gouri, Pe’er, Dana, Cleveland, Don W., Powell, Simon N., Lammerding, Jan, Swanton, Charles, Cantley, Lewis C.

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Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin von Sun, Kun, Jiang, Peiyong, Cheng, Suk Hang, Cheng, Timothy H T, Wong, John, Wong, Vincent W S, Ng, Simon S M, Ma, Brigette B Y, Leung, Tak Y, Chan, Stephen L, Mok, Tony S K, Lai, Paul B S, Chan, Henry L Y, Sun, Hao, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis

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Precautions and Procedures for Coronary and Structural Cardiac Interventions During the COVID-19 Pandemic: Guidance from Canadian Association of Interventional Cardiology von Wood, David A., Sathananthan, Janarthanan, Gin, Ken, Mansour, Samer, Ly, Hung Q., Quraishi, Ata-ur-Rehman, Lavoie, Andrea, Lutchmedial, Sohrab, Nosair, Mohamed, Bagai, Akshay, Bainey, Kevin R., Boone, Robert H., Liu, Shuangbo, Krahn, Andrew, Virani, Sean, Mehta, Shamir R., Natarajan, Madhu K., Velianou, James L., Dehghani, Payam, Wijeysundera, Harindra C., Asgar, Anita W., Virani, Alice, Welsh, Robert C., Webb, John G., Cohen, Eric A.

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Two big bones, one big decision: When to fix bilateral femur fractures von Arnold, Suzanne C., Lagazzi, Emanuele, Wagner, Robert K., Rafaqat, Wardah, Abiad, May, Argandykov, Dias, Hoekman, Anne H., Panossian, Vahe, Nzenwa, Ikemsinachi C., Cote, Mark, Hwabejire, John O., Schipper, Inger B., Ly, Thuan V., Velmahos, George C.

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Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data von Campbell, Bruce C V, Leys, Didier, Molina, Carlos, Curtze, Sami, De Silva, Deidre A, Bladin, Christopher F, Pfaff, Johannes A R, Sharma, Gagan, Desmond, Patricia M, Toni, Danilo, Thijs, Vincent, Churilov, Leonid, Yan, Bernard, Mitchell, Peter J., Sharma, Gagan, Desmond, Patricia M., Oxley, Thomas, Rodrigues, Edrich, Williams, Cameron, Ng, Jo-Lyn, Tu, Hans T-H., McCoy, Rachael, Patel, S., Harvey, J., Cheong, E., Waters, Michael, Wijeratne, Tissa, Bladin, Christopher F., Loh, Poh Sien, Coote, Skye, Moore, A., Ross, Z., Miteff, Ferdinand, Ang, Timothy, Garcia-Esperon, Carlos, Krause, Martin, Day, Susan, Young, Dennis, Wong, Andrew A., Muller, Claire, Vallat, W., Bailey, Peter, Sabet, Arman, Mishra, Sachin, Tan, Meng, George, K., Tatlisumak, Turgut, Sibolt, G., Tiainen, M., Koivu, M., Eirola, S., Lin, C.M., Ho, S.C., Tsai, C.H., Lu, C.H., Kung, W.L., Jiang, S.K., Kuan, C.W., Tsai, H.T., Lu, C.J., Ysai, C.L., Jeng, J.S., Tang, S.C., Chung, T.C., Hu, C.J., Chan, L., Yeh, H.L., Peng, G.S., Cheng, C.A., Hsu, C.H., Sung, Y.F., Blacker, David, Chen, C-I., Cowley, Elise, Kolbe, John, Macdonnell, Richard, Attia, John, Cadilhac, Dominique, Anderson, Craig, Howells, David, Barber, A., Bendszus, Martin, Hacke, Werner, Ringleb, Peter, Toni, Danilo, Ehrenkrona, Christina, Cove, Lynda, Niederkorn, Kurt, Mikulik, Robert, Mas, Jean-Louis, Berrouschot, Jörg, Sobesky, Jan, Kessler, Christof, Poli, Sven, Althaus-Knaurer, Katharina, Rodriguez, Alain L., Muir, Keith, Fink, John N., McNeil, John, Williams, M.

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The Cardiac Genome Clinic: implementing genome sequencing in pediatric heart disease von Reuter, Miriam S., Chaturvedi, Rajiv R., Liston, Eriskay, Manshaei, Roozbeh, Aul, Ritu B., Bowdin, Sarah, Cohn, Iris, Curtis, Meredith, Dhir, Priya, Hayeems, Robin Z., Hosseini, S. Mohsen, Khan, Reem, Ly, Linh G., Marshall, Christian R., Mertens, Luc, Okello, John B. A., Pereira, Sergio L., Raajkumar, Akshaya, Seed, Mike, Thiruvahindrapuram, Bhooma, Scherer, Stephen W., Kim, Raymond H., Jobling, Rebekah K.

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Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine von Weisbord, Steven D, Gallagher, Martin, Jneid, Hani, Garcia, Santiago, Cass, Alan, Thwin, Soe-Soe, Conner, Todd A, Chertow, Glenn M, Bhatt, Deepak L, Shunk, Kendrick, Parikh, Chirag R, McFalls, Edward O, Brophy, Mary, Ferguson, Ryan, Wu, Hongsheng, Androsenko, Maria, Myles, John, Kaufman, James, Palevsky, Paul M

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Targeted Delivery of microRNA-29b by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia von XIAOMENG HUANG, SCHWIND, Sebastian, BLUM, William, PERROTTI, Danilo, BYRD, John C, BLOOMFIELD, Clara D, CALIGIURI, Michael A, LEE, Robert J, GARZON, Ramiro, MUTHUSAMY, Natarajan, LEE, Ly James, MARCUCCI, Guido, BO YU, SANTHANAM, Ramasamy, HONGYAN WANG, HOELLERBAUER, Pia, MIMS, Alice, KLISOVIC, Rebecca, WALKER, Alison R, CHAN, Kenneth K

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Krüppel-Like Factor 15 Mediates Glucocorticoid-Induced Restoration of Podocyte Differentiation Markers von Mallipattu, Sandeep K, Guo, Yiqing, Revelo, Monica P, Roa-Peña, Lucia, Miller, Timothy, Ling, Jason, Shankland, Stuart J, Bialkowska, Agnieszka B, Ly, Victoria, Estrada, Chelsea, Jain, Mukesh K, Lu, Yuan, Ma'ayan, Avi, Mehrotra, Anita, Yacoub, Rabi, Nord, Edward P, Woroniecki, Robert P, Yang, Vincent W, He, John C

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Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes von Brouwer, Stephan, Barnett, Timothy C., Ly, Diane, Kasper, Katherine J., De Oliveira, David M. P., Rivera-Hernandez, Tania, Cork, Amanda J., McIntyre, Liam, Jespersen, Magnus G., Richter, Johanna, Schulz, Benjamin L., Dougan, Gordon, Nizet, Victor, Yuen, Kwok-Yung, You, Yuanhai, McCormick, John K., Sanderson-Smith, Martina L., Davies, Mark R., Walker, Mark J.

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