Osteoclasts in multiple myeloma are derived from Gr-1+CD11b+myeloid-derived suppressor cells von Zhuang, Junling, Zhang, Jianghong, Lwin, Seint T, Edwards, James R, Edwards, Claire M, Mundy, Gregory R, Yang, Xiangli

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Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease von Fowler, Jessica A., Lwin, Seint T., Drake, Matthew T., Edwards, James R., Kyle, Robert A., Mundy, Gregory R., Edwards, Claire M.

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Bone Marrow Stromal Cells Create a Permissive Microenvironment for Myeloma Development: A New Stromal Role for Wnt Inhibitor Dkk1 von FOWLER, Jessica A, MUNDY, Gregory R, LWIN, Seint T, EDWARDS, Claire M

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Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo von Edwards, Claire M., Edwards, James R., Lwin, Seint T., Esparza, Javier, Oyajobi, Babatunde O., McCluskey, Brandon, Munoz, Steven, Grubbs, Barry, Mundy, Gregory R.

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Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment von Olechnowicz, Sam W. Z., Weivoda, Megan M., Lwin, Seint T., Leung, Szi K., Gooding, Sarah, Nador, Guido, Javaid, Muhammed Kassim, Ramasamy, Karthik, Rao, Srinivasa R., Edwards, James R., Edwards, Claire M.

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Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo von Edwards, Claire M., Lwin, Seint T., Fowler, Jessica A., Oyajobi, Babatunde O., Zhuang, Junling, Bates, Andreia L., Mundy, Gregory R.

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Silent information regulator (Sir)T1 inhibits NF‐κB signaling to maintain normal skeletal remodeling von Edwards, James R, Perrien, Daniel S, Fleming, Nicole, Nyman, Jeffry S, Ono, Koichiro, Connelly, Linda, Moore, Megan M, Lwin, Seint T, Yull, Fiona E, Mundy, Gregory R, Elefteriou, Florent

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Silent information regulator (Sir)T1 inhibits NF-[kappa]B signaling to maintain normal skeletal remodeling von Edwards, James R, Perrien, Daniel S, Fleming, Nicole, Nyman, Jeffry S, Ono, Koichiro, Connelly, Linda, Moore, Megan M, Lwin, Seint T, Yull, Fiona E, Mundy, Gregory R, Elefteriou, Florent

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A murine model of myeloma that allows genetic manipulation of the host microenvironment von Fowler, Jessica A, Mundy, Gregory R, Lwin, Seint T, Lynch, Conor C, Edwards, Claire M

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Inhibition of TGF‐β signaling by 1D11 antibody treatment increases bone mass and quality in vivo von Edwards, James R, Nyman, Jeffry S, Lwin, Seint T, Moore, Megan M, Esparza, Javier, O'Quinn, Elizabeth C, Hart, Andrew J, Biswas, Swati, Patil, Chetan A, Lonning, Scott, Mahadevan‐Jansen, Anita, Mundy, Gregory R

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Preclinical animal models of multiple myeloma von Lwin, Seint T, Edwards, Claire M, Silbermann, Rebecca

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Calmodulin kinase II inhibition disrupts cardiomyopathic effects of enhanced green fluorescent protein von Khoo, Michelle S.C, Grueter, Chad E, Eren, Mesut, Yang, Jinying, Zhang, Rong, Bass, Martha A, Lwin, Seint T, Mendes, Lisa A, Vaughan, Douglas E, Colbran, Roger J, Anderson, Mark E

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Cholesterol promotes myeloma cell viability and increases bone marrow myeloma tumour burden in vivo von Gamez, Beatriz, Morris, Emma V., Olechnowicz, Sam W.Z., Aneka, Sowman, Turner, Christina J., Lwin, Seint T., Drake, Matthew T., Edwards, Claire M.

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Differential effects of host-derived mmps on development of multiple myeloma in vivo von Edwards, Claire M, Lynch, Conor C, Fowler, Jessica A, Carter, Kathy, Lwin, Seint T, Matrisian, Lynn M, Mundy, Gregory R

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Osteoclasts in Myeloma Are Derived from Gr-1+CD11b+ Myeloid Immune Suppressor Cells of the Bone Marrow Niche in Vivo von Zhuang, Junling, Yang, Li, Lwin, Seint T, Edwards, Claire M., Edwards, James R, Mundy, Gregory R

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Inhibition of TGF-[beta] signaling by 1D11 antibody treatment increases bone mass and quality in vivo von Edwards, James R, Nyman, Jeffry S, Lwin, Seint T, Moore, Megan M, Esparza, Javier, O'Quinn, Elizabeth C, Hart, Andrew J, Biswas, Swati, Patil, Chetan A, Lonning, Scott, Mahadevan-Jansen, Anita, Mundy, Gregory R

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Targeting Wnt Signaling in Myeloma In Vivo; Differential Effects on Tumor Burden and Myeloma Bone Disease von Edwards, Claire M., Edwards, James R., Lwin, Seint T., Mundy, Gregory R.

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Inhibition of TGF-β Signaling by 1 D11 Antibody Treatment Increases Bone Mass and Quality In Vivo von EDWARDS, James R, NYMAN, Jeffry S, MAHADEVAN-JANSEN, Anita, MUNDY, Gregory R, LWIN, Seint T, MOORE, Megan M, ESPARZA, Javier, O'QUINN, Elizabeth C, HART, Andrew J, BISWAS, Swati, PATIL, Chetan A, LONNING, Scott

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Protein Profiling in Myeloma In Vivo; Effects of Bortezomib in a Mouse Model of Myeloma von Edwards, Claire M., Caldwell, Robert L., Bates, Andreia L., Fowler, Jessica A., Edwards, James R., Oyajobi, Babatunde O., Lwin, Seint T., Zhang, Jianghong, Mundy, Gregory R.

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Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300 von Sacitharan, Pradeep K., Lwin, Seint, Gharios, George Bou, Edwards, James R.

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