Cellular Characterization of a Novel Focal Adhesion Kinase Inhibitor von Slack-Davis, Jill K., Martin, Karen H., Tilghman, Robert W., Iwanicki, Marcin, Ung, Ethan J., Autry, Christopher, Luzzio, Michael J., Cooper, Beth, Kath, John C., Roberts, W. Gregory, Parsons, J. Thomas

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Design of Selective, ATP-Competitive Inhibitors of Akt von Freeman-Cook, Kevin D, Autry, Christopher, Borzillo, Gary, Gordon, Deborah, Barbacci-Tobin, Elsa, Bernardo, Vincent, Briere, David, Clark, Tracey, Corbett, Matthew, Jakubczak, John, Kakar, Shefali, Knauth, Elizabeth, Lippa, Blaise, Luzzio, Michael J, Mansour, Mahmoud, Martinelli, Gary, Marx, Matthew, Nelson, Kendra, Pandit, Jayvardhan, Rajamohan, Francis, Robinson, Shaughnessy, Subramanyam, Chakrapani, Wei, Liuqing, Wythes, Martin, Morris, Joel

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Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis von Buckbinder, Leonard, Crawford, David T, Qi, Hong, Ke, Hua Zhu, Olson, Lisa M, Long, Kelly R, Bonnette, Peter C, Baumann, Amy P, Hambor, John E, Grasser, William A. III, Pan, Lydia C, Owen, Thomas A, Luzzio, Michael J, Hulford, Catherine A, Gebhard, David F, Paralkar, Vishwas M, Simmons, Hollis A, Kath, John C, Roberts, W. Gregory, Smock, Steven L, Guzman-Perez, Angel, Brown, Thomas A, Li, Mei

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Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors von Himmelbauer, Martin K, Xin, Zhili, Jones, J. Howard, Enyedy, Istvan, King, Kristopher, Marcotte, Douglas J, Murugan, Paramasivam, Santoro, Joseph C, Hesson, Thomas, Spilker, Kerri, Johnson, Joshua L, Luzzio, Michael J, Gilfillan, Rab, de Turiso, Felix Gonzalez-Lopez

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Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2):  Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis von Bramson, H. Neal, Corona, John, Davis, Stephen T, Dickerson, Scott H, Edelstein, Mark, Frye, Stephen V, Gampe, Robert T, Harris, Phil A, Hassell, Anne, Holmes, William D, Hunter, Robert N, Lackey, Karen E, Lovejoy, Brett, Luzzio, Michael J, Montana, Val, Rocque, Warren J, Rusnak, David, Shewchuk, Lisa, Veal, James M, Walker, Duncan H, Kuyper, Lee F

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Synthesis and Antitumor Activity of Novel Water Soluble Derivatives of Camptothecin as Specific Inhibitors of Topoisomerase I von Luzzio, Michael J, Besterman, Jeffrey M, Emerson, David L, Evans, Michael G, Lackey, Karen, Leitner, Peter L, McIntyre, Gordon, Morton, Bradley, Myers, Peter L, Peel, Michael, Sisco, Jay M, Sternbach, Daniel D, Tong, Wei-Qin, Truesdale, Ann, Uehling, David E, Vuong, Alan, Yates, Julie

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Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2) : Structure-activity relationships and strategies for the elimination of reactive metabolite for... von WALKER, Daniel P, BI, F. Christopher, MCGLYNN, Molly A, OLIVER, Robert, DUNN, Matthew, LI, Jian-Cheng, RICHTER, Daniel T, COOPER, Beth A, KATH, John C, HULFORD, Catherine A, AUTRY, Christopher L, LUZZIO, Michael J, KALGUTKAR, Amit S, UNG, Ethan J, ROBERTS, W. Gregory, BONNETTE, Peter C, BUCKBINDER, Leonard, MISTRY, Anil, GRIFFOR, Matthew C, HAN, Seungil, GUZMAN-PEREZ, Angel, BAUMAN, Jonathan N, ZHAO, Sabrina X, SOGLIA, John R, ASPNES, Gary E, KUNG, Daniel W, KLUG-MCLEOD, Jacquelyn, ZAWISTOSKI, Michael P

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Synthesis, Topoisomerase I Inhibitory Activity, and in Vivo Evaluation of 11-Azacamptothecin Analogs von Uehling, David E, Nanthakumar, Suganthini S, Croom, Dallas, Emerson, David L, Leitner, Peter P, Luzzio, Michael J, McIntyre, Gordon, Morton, Bradley, Profeta, Salvadore

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Corrections to Design of Selective, ATP-Competitive Inhibitors of Akt von Freeman-Cook, Kevin D, Autry, Christopher, Borzillo, Gary, Gordon, Deborah, Barbacci-Tobin, Elsa, Bernardo, Vincent, Briere, David, Clark, Tracey, Corbett, Matthew, Jakubczak, John, Kakar, Shefali, Knauth, Elizabeth, Lippa, Blaise, Luzzio, Michael J, Mansour, Mahmoud, Martinelli, Gary, Marx, Matthew, Nelson, Kendra, Pandit, Jayvardhan, Rajamohan, Francis, Robinson, Shaughnessy, Subramanyam, Chakrapani, Wei, Liuqing, Wythes, Martin, Morris, Joel

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Antitumor Efficacy, Pharmacokinetics, and Biodistribution of NX 211: A Low-Clearance Liposomal Formulation of Lurtotecan von EMERSON, D. L, BENDELE, R, MOYNIHAN, K, RICHARDSON, F. C, TOMKINSON, B, LUZZIO, M. J, BACCANARI, D, BROWN, E, SUMING CHIANG, DESJARDINS, J. P, DIHEL, L. C, GILL, S. C, HAMILTON, M, LERAY, J. D, MOON-MCDERMOTT, L

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Selective addition of amines to 5-trifluoromethyl-2,4-dichloropyrimidine induced by Lewis acids von Richter, Daniel T., Kath, John C., Luzzio, Michael J., Keene, Nandell, Berliner, Martin A., Wessel, Matthew D.

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In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues von EMERSON, D. L, BESTERMAN, J. M, BROWN, H. R, EVANS, M. G, LEITNER, P. P, LUZZIO, M. J, SHAFFER, J. E, STERNBACH, D. D, UEHLING, D, VUONG, A

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Total synthesis of (.+-.)-7-epi-20-desethylgelsedine von Kende, Andrew S, Luzzio, Michael J, Mendoza, Jose S

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Water Soluble Inhibitors of Topoisomerase I:  Quaternary Salt Derivatives of Camptothecin von Lackey, Karen, Sternbach, Daniel D, Croom, Dallas K, Emerson, David L, Evans, Michael G, Leitner, Peter L, Luzzio, Michael J, McIntyre, Gordon, Vuong, Alain, Yates, Julie, Besterman, Jeffrey M

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Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors von Davis, Stephen T., Benson, Bill G., Bramson, H. Neal, Chapman, Dennis E., Dickerson, Scott H., Dold, Karen M., Eberwein, Derek J., Edelstein, Mark, Frye, Stephen V., Gampe, Robert T., Griffin, Robert J., Harris, Philip A., Hassell, Anne M., Holmes, William D., Hunter, Robert N., Knick, Victoria B., Lackey, Karen, Lovejoy, Brett, Luzzio, Michael J., Murray, Doris, Parker, Patricia, Rocque, Warren J., Shewchuk, Lisa, Veal, James M., Walker, Duncan H., Kuyper, Lee F.

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Enantioselectively catalyzed intramolecular cyclopropanations of unsaturated diazo carbonyl compounds von Dauben, William G., Hendricks, Robert T., Luzzio, Michael J., Ng, Howard P.

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Fmoc mediated synthesis of Peptide Nucleic Acids von Thomson, Stephen A., Josey, John A., Cadilla, Rodolfo, Gaul, Micheal D., Fred Hassman, C., Luzzio, Michael J., Pipe, Adrian J., Reed, Kathryn L., Ricca, Daniel J., Wiethe, Robert W., Noble, Stewart A.

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ChemInform Abstract: Selective Addition of Amines to 5-Trifluoromethyl-2,4-dichloropyrimidine Induced by Lewis Acids von Richter, Daniel T., Kath, John C., Luzzio, Michael J., Keene, Nandell, Berliner, Martin A., Wessel, Matthew D.

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Cancer von Gilmer, Tona M., Luzzio, Michael J.

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Cancer von Gilmer, Tona M., Luzzio, Michael J.

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