Vδ2 T-cell engagers bivalent for Vδ2-TCR binding provide anti-tumor immunity and support robust Vγ9Vδ2 T-cell expansion von King, Lisa A, de Jong, Milon, Veth, Myrthe, Lutje Hulsik, David, Yousefi, Parsa, Iglesias-Guimarais, Victoria, van Helden, Pauline M, de Gruijl, Tanja D, van der Vliet, Hans J

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Functional characterization of the selective pan-allele anti-SIRPα antibody ADU-1805 that blocks the SIRPα–CD47 innate immune checkpoint von Voets, Erik, Paradé, Marc, Lutje Hulsik, David, Spijkers, Sanne, Janssen, Wout, Rens, Joost, Reinieren-Beeren, Inge, van den Tillaart, Gilbert, van Duijnhoven, Sander, Driessen, Lilian, Habraken, Maurice, van Zandvoort, Peter, Kreijtz, Joost, Vink, Paul, van Elsas, Andrea, van Eenennaam, Hans

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Epitope mapping of monoclonal antibodies: a comprehensive comparison of different technologies von Dang, Xibei, Guelen, Lars, Lutje Hulsik, David, Ermakov, Grigori, Hsieh, Edward J, Kreijtz, Joost, Stammen-Vogelzangs, Judith, Lodewijks, Imke, Bertens, Astrid, Bramer, Arne, Guadagnoli, Marco, Nazabal, Alexis, van Elsas, Andrea, Fischmann, Thierry, Juan, Veronica, Beebe, Amy, Beaumont, Maribel, van Eenennaam, Hans

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Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41 von Sabin, Charles, Corti, Davide, Buzon, Victor, Seaman, Mike S, Lutje Hulsik, David, Hinz, Andreas, Vanzetta, Fabrizia, Agatic, Gloria, Silacci, Chiara, Mainetti, Lara, Scarlatti, Gabriella, Sallusto, Federica, Weiss, Robin, Lanzavecchia, Antonio, Weissenhorn, Winfried

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Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions von Lameris, Roeland, Shahine, Adam, Veth, Myrthe, Westerman, Bart, Godfrey, Dale I, Lutje Hulsik, David, Brouwer, Patricia, Rossjohn, Jamie, de Gruijl, Tanja D, van der Vliet, Hans J

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Structural Basis for ESCRT-III CHMP3 Recruitment of AMSH von Solomons, Julianna, Sabin, Charles, Poudevigne, Emilie, Usami, Yoshiko, Hulsik, David Lutje, Macheboeuf, Pauline, Hartlieb, Bettina, Göttlinger, Heinrich, Weissenhorn, Winfried

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Isolation of Llama Antibody Fragments for Prevention of Dandruff by Phage Display in Shampoo von Dolk, Edward, van der Vaart, Marcel, Lutje Hulsik, David, Vriend, Gert, de Haard, Hans, Spinelli, Silvia, Cambillau, Christian, Frenken, Leon, Verrips, Theo

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Crystal Structure of the Neutralizing Llama VHH D7 and Its Mode of HIV-1 gp120 Interaction von Hinz, Andreas, Lutje Hulsik, David, Forsman, Anna, Koh, Willie Wee-Lee, Belrhali, Hassan, Gorlani, Andrea, de Haard, Hans, Weiss, Robin A., Verrips, Theo, Weissenhorn, Winfried

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Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodeling von de Morrée, Antoine, Lutje Hulsik, David, Impagliazzo, Antonietta, van Haagen, Herman H H B M, de Galan, Paula, van Remoortere, Alexandra, 't Hoen, Peter A C, van Ommen, Gertjan B, Frants, Rune R, van der Maarel, Silvère M

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A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition von Lutje Hulsik, David, Liu, Ying-ying, Strokappe, Nika M, Battella, Simone, El Khattabi, Mohamed, McCoy, Laura E, Sabin, Charles, Hinz, Andreas, Hock, Miriam, Macheboeuf, Pauline, Bonvin, Alexandre M J J, Langedijk, Johannes P M, Davis, David, Forsman Quigley, Anna, Aasa-Chapman, Marlén M I, Seaman, Michael S, Ramos, Alejandra, Poignard, Pascal, Favier, Adrien, Simorre, Jean-Pierre, Weiss, Robin A, Verrips, C Theo, Weissenhorn, Winfried, Rutten, Lucy

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Llama antibody fragments recognizing various epitopes of the CD4bs neutralize a broad range of HIV-1 subtypes A, B and C von Strokappe, Nika, Szynol, Agnieszka, Aasa-Chapman, Marlèn, Gorlani, Andrea, Forsman Quigley, Anna, Hulsik, David Lutje, Chen, Lei, Weiss, Robin, de Haard, Hans, Verrips, Theo

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Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy von Guelen, Lars, Fischmann, Thierry O, Wong, Jerelyn, Mauze, Smita, Guadagnoli, Marco, Bąbała, Nikolina, Wagenaars, Jozef, Juan, Veronica, Rosen, David, Prosise, Winnie, Habraken, Maurice, Lodewijks, Imke, Gu, Danling, Stammen-Vogelzangs, Judith, Yu, Ying, Baker, Jeanne, Lutje Hulsik, David, Driessen-Engels, Lilian, Malashock, Dan, Kreijtz, Joost, Bertens, Astrid, de Vries, Evert, Bovens, Astrid, Bramer, Arne, Zhang, Yiwei, Wnek, Richard, Troth, Sean, Chartash, Elliot, Dobrenkov, Konstantin, Sadekova, Svetlana, van Elsas, Andrea, Cheung, Jason K, Fayadat-Dilman, Laurence, Borst, Jannie, Beebe, Amy M, Van Eenennaam, Hans

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Leveraging Vγ9Vδ2 T cells against prostate cancer through a VHH-based PSMA-Vδ2 bispecific T cell engager von King, Lisa A., Veth, Myrthe, Iglesias-Guimarais, Victoria, Blijdorp, Iris, Kloosterman, Jan, Vis, André N., Roovers, Rob C., Hulsik, David Lutje, Riedl, Thilo, Adang, Anton E.P., Parren, Paul W.H.I., van Helden, Pauline M., de Gruijl, Tanja D., van der Vliet, Hans J.

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Charged Multivesicular Body Protein 2B (CHMP2B) of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III) Polymerizes into Helical Structures Deforming the Plasma Mem... von Bodon, Gilles, Chassefeyre, Romain, Pernet-Gallay, Karin, Martinelli, Nicolas, Effantin, Grégory, Hulsik, David Lutje, Belly, Agnès, Goldberg, Yves, Chatellard-Causse, Christine, Blot, Béatrice, Schoehn, Guy, Weissenhorn, Winfried, Sadoul, Rémy

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A novel efficient bispecific antibody format, combining a conventional antigen-binding fragment with a single domain antibody, avoids potential heavy-light chain mis-pairing von Huang, Shuyu, Segués, Aina, Hulsik, David Lutje, Zaiss, Dietmar M, Sijts, Alice J A M, van Duijnhoven, Sander M J, van Elsas, Andrea

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A novel efficient bispecific antibody format, combining a conventional antigen-binding fragment with a single domain antibody, avoids potential heavy-light chain mis-pairing von Huang, Shuyu, Segués, Aina, Hulsik, David Lutje, Zaiss, Dietmar M., Sijts, Alice J.A.M., van Duijnhoven, Sander M.J., van Elsas, Andrea

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Abstract 1203: Preclinical development of ADU-1805, a highly selective pan-allele anti-SIRPα antibody that blocks the SIRPα-CD47 innate immune checkpoint von Voets, Erik, Kreijtz, Joost, Vink, Paul, Hulsik, David Lutje, Parade, Mark, Spijkers, Sanne, Reinieren-Beeren, Inge, Rens, Joost, Janssen, Wout, Zandvoort, Peter van, Francica, Brian, Leong, Meredith, Elsas, Andrea van, Eenennaam, Hans van

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Abstract 2645: Development of a first in class APRIL fully blocking antibody BION-1301 for the treatment of multiple myeloma von Dulos, John, Driessen, Lilian, Snippert, Marc, Guadagnoli, Marco, Bertens, Astrid, Hulsik, David Lutje, Tzu, Tai Yu, Anderson, Kenneth, Medema, Jan Paul, Cameron, Kate, Eenennaam, Hans, Elsas, Andrea

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Abstract 1702: Assessment of pharmacology and toxicology of anti-CTLA-4 antibody (ADU-1604) in non-human primates and evaluation of local anti-CTLA-4 application von Hendriks, Maaike, Kreijtz, Joost, Vink, Paul, Hulsik, David Lutje, Lodewijks, Imke, Bertens, Astrid, Crommert, Jos van de, Habraken, Maurice, Janssen, Wout, Stammen-Vogelzang, Judith, Gardner, Olivia, Deng, Weiwen, Leong, Meredith, McWhirter, Sarah, Eenennaam, Hans van, Elsas, Andrea van

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A Fusion Intermediate gp41 Immunogen Elicits Neutralizing Antibodies to HIV-1 von Lai, Rachel P.J., Hock, Miriam, Radzimanowski, Jens, Tonks, Paul, Hulsik, David Lutje, Effantin, Gregory, Seilly, David J., Dreja, Hanna, Kliche, Alexander, Wagner, Ralf, Barnett, Susan W., Tumba, Nancy, Morris, Lynn, LaBranche, Celia C., Montefiori, David C., Seaman, Michael S., Heeney, Jonathan L., Weissenhorn, Winfried

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