Design, Synthesis, and Structure−Activity Relationships of Novel Insulin Receptor Tyrosine Kinase Activators von Lum, Robert T, Cheng, Mingshan, Cristobal, Cristina P, Goldfine, Ira D, Evans, Joseph L, Keck, James G, Macsata, Robert W, Manchem, Vara Prasad, Matsumoto, Yukiharu, Park, Sophia J, Rao, Sandhya S, Robinson, Louise, Shi, Songyuan, Spevak, Wayne R, Schow, Steven R

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A Novel Small Molecule That Directly Sensitizes the Insulin Receptor In Vitro and In Vivo von VARA PRASAD MANCHEM, GOLDFINE, Ira D, VILLAR, Hugo O, WICK, Michael M, KOZLOWSKI, Michael R, KOHANSKI, Ronald A, CRISTOBAL, Cristina P, LUM, Robert T, SCHOW, Steven R, SHI, Songyuan, SPEVAK, Wayne R, LABORDE, Edgardo, TOAVS, Deborah K

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Phase I Study of TLK286 (Glutathione S-Transferase P1-1 Activated Glutathione Analogue) in Advanced Refractory Solid Malignancies von ROSEN, Lee S, BROWN, Joseph, MASCAVAGE, Julie C, DOMBROSKI, Jacqueline A, GOMEZ, Reinaldo F, BROWN, Gail L, LAXA, Bernadette, BOULOS, Leny, REISWIG, Laura, HENNER, William D, LUM, Robert T, SCHOW, Steve R, MAACK, Christopher A, KECK, James G

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CVT-313, a Specific and Potent Inhibitor of CDK2 That Prevents Neointimal Proliferation von Brooks, Eric E., Gray, Nathanael S., Joly, Alison, Kerwar, Suresh S., Lum, Robert, Mackman, Richard L., Norman, Thea C., Rosete, Jose, Rowe, Michael, Schow, Steven R., Schultz, Peter G., Wang, Xingbo, Wick, Michael M., Shiffman, Dov

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5-Substituted isophthalamides as insulin receptor sensitizers von Robinson, Louise, Bajjalieh, Sonia, Cairns, Nicholas, Lum, Robert T., Macsata, Robert W., Manchem, Vara Prasad, Park, Sophia J., Rao, Sandhya, Schow, Steven R., Shi, Songyuan, Spevak, Wayne R.

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In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator von Cheng, Mingshan, Chen, Seiyu, Schow, Steven R., Manchem, Vara Prasad, Spevak, Wayne R., Cristobal, Cristina P., Shi, Songyuan, Macsata, Robert W., Lum, Robert T., Goldfine, Ira D., Keck, James G.

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Synthesis and Biological Evaluation of the Enantiomers of the Potent and Selective A1-Adenosine Antagonist 1,3-Dipropyl-8-[2-(5,6-epoxynorbonyl)]- xanthine von Pfister, Jürg R, Belardinelli, Luiz, Lee, Gavin, Lum, Robert T, Milner, Peter, Stanley, William C, Linden, Joel, Baker, Stephen P, Schreiner, George

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A New Structural Class of Proteasome Inhibitors that Prevent NF-κB Activation von Lum, Robert T, Kerwar, Suresh S, Meyer, Stephanie M, Nelson, Marek G, Schow, Steven R, Shiffman, Dov, Wick, Michael M, Joly, Alison

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Novel Cyclooxygenase-1 Inhibitors Discovered Using Affinity Fingerprints von Hsu, Nancy, Cai, Danying, Damodaran, Komath, Gomez, Reinaldo F, Keck, James G, Laborde, Edgardo, Lum, Robert T, Macke, Thomas J, Martin, Graeme, Schow, Steven R, Simon, Reyna J, Villar, Hugo O, Wick, Michael M, Beroza, Paul

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Synthesis, structure, and reactions of a zirconocene-cyclohexyne complex von Buchwald, Stephen L, Lum, Robert T, Dewan, John C

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Synthesis and x-ray crystal structure of a zirconocene complex of a cyclopentyne and its use to prepare bicyclic cyclopentenones von Buchwald, Stephen L, Lum, Robert T, Fisher, Richard A, Davis, William M

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A general method for the preparation of zirconocene complexes of substituted benzynes: in situ generation, coupling reactions, and use in the synthesis of polyfunctionalized aromat... von Buchwald, Stephen L, Watson, Brett T, Lum, Robert T, Nugent, William A

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Selective inhibition of the chymotrypsin-like activity of the 20S proteasome by 5-methoxy-1-indanone dipeptide benzamides von Lum, Robert T., Nelson, Marek G., Joly, Alison, Horsma, Amy G., Lee, Gavin, Meyer, Stephanie M., Wick, Michael M., Schow, Steven R.

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A comparison of an A 1 adenosine receptor agonist (CVT‐510) with diltiazem for slowing of AV nodal conduction in guinea‐pig von Snowdy, Stephen, Liang, Hui Xiu, Blackburn, Brent, Lum, Robert, Nelson, Marek, Wang, Lisa, Pfister, Jürg, Sharma, Bhavender P, Wolff, Andrew, Belardinelli, Luiz

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A fast algorithm for representing continuous piecewise linear functions in closed form von Lum, Robert, Chua, Leon O.

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DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS von LUM, Robert, DAVIDSON, Matthew, SCHOW, Steven R, SAIKI, Julie

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DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS von LUM, Robert, DAVIDSON, Matthew, SCHOW, Steven R, SAIKI, Julie

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DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS von LUM, Robert, DAVIDSON, Matthew, SCHOW, Steven R, SAIKI, Julie

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How to represent continuous piecewise linear functions in closed form von Lum, Robert, Chua, Leon O.

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Synthesis and antiviral activity of a novel class of HIV-1 protease inhibitors containing a heterocyclic P1′-P2′ amide bond isostere von Thompson, Scott K., Eppley, Alecia M., Frazee, James S., Darcy, Michael G., Lum, Robert T., Tomaszek, Thaddeus A., Ivanoff, Lucinda A., Morris, Jane F., Sternberg, Edmund J., Lambert, Dennis M., Fernandez, Annabellee V., Petteway, Stephen R., Meek, Thomas D, Metcalf, Brian W., Gleason, John G.

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