Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug-Resistance Mechanisms in a Leukemia Model von Halley, Patrick D., Lucas, Christopher R., McWilliams, Emily M., Webber, Matthew J., Patton, Randy A., Kural, Comert, Lucas, David M., Byrd, John C., Castro, Carlos E.

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Anti-leukemic activity of bortezomib and carfilzomib on B-cell precursor ALL cell lines von Takahashi, Kazuya, Inukai, Takeshi, Imamura, Toshihiko, Yano, Mio, Tomoyasu, Chihiro, Lucas, David M, Nemoto, Atsushi, Sato, Hiroki, Huang, Meixian, Abe, Masako, Kagami, Keiko, Shinohara, Tamao, Watanabe, Atsushi, Somazu, Shinpei, Oshiro, Hiroko, Akahane, Koshi, Goi, Kumiko, Kikuchi, Jiro, Furukawa, Yusuke, Goto, Hiroaki, Minegishi, Masayoshi, Iwamoto, Shotaro, Sugita, Kanji

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Tetraspanin CD37 Directly Mediates Transduction of Survival and Apoptotic Signals von Lapalombella, Rosa, Yeh, Yuh-Ying, Wang, Liwen, Ramanunni, Asha, Rafiq, Sarwish, Jha, Shruti, Staubli, Justin, Lucas, David M., Mani, Rajeswaran, Herman, Sarah E.M., Johnson, Amy J., Lozanski, Arletta, Andritsos, Leslie, Jones, Jeffrey, Flynn, Joseph M., Lannutti, Brian, Thompson, Peter, Algate, Paul, Stromatt, Scott, Jarjoura, David, Mo, Xiaokui, Wang, Dasheng, Chen, Ching-Shih, Lozanski, Gerard, Heerema, Nyla A., Tridandapani, Susheela, Freitas, Michael A., Muthusamy, Natarajan, Byrd, John C.

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Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species von Pan, Li, Woodard, John L, Lucas, David M, Fuchs, James R, Douglas Kinghorn, A

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The interleukin-3 receptor CD123 targeted SL-401 mediates potent cytotoxic activity against CD34 + CD123 + cells from acute myeloid leukemia/myelodysplastic syndrome patients and h... von Mani, Rajeswaran, Goswami, Swagata, Gopalakrishnan, Bhavani, Ramaswamy, Rahul, Wasmuth, Ronni, Tran, Minh, Mo, Xiaokui, Gordon, Amber, Bucci, Donna, Lucas, David M, Mims, Alice, Brooks, Christopher, Dorrance, Adrienne, Walker, Alison, Blum, William, Byrd, John C, Lozanski, Gerard, Vasu, Sumithira, Muthusamy, Natarajan

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Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer von Kogure, Takayuki, Kinghorn, A Douglas, Yan, Irene, Bolon, Brad, Lucas, David M, Grever, Michael R, Patel, Tushar

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The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo von Lucas, David M., Edwards, Ryan B., Lozanski, Gerard, West, Derek A., Shin, Jungook D., Vargo, Melissa A., Davis, Melanie E., Rozewski, Darlene M., Johnson, Amy J., Su, Bao-Ning, Goettl, Virginia M., Heerema, Nyla A., Lin, Thomas S., Lehman, Amy, Zhang, Xiaoli, Jarjoura, David, Newman, David J., Byrd, John C., Kinghorn, A. Douglas, Grever, Michael R.

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Comprehensive Assessment of Genetic and Molecular Features Predicting Outcome in Patients With Chronic Lymphocytic Leukemia: Results From the US Intergroup Phase III Trial E2997 von GREVER, Michael R, LUCAS, David M, PAIETTA, Elisabeth, JELINEK, Diane F, GRIBBEN, John G, BYRD, John C, DEWALD, Gordon W, NEUBERG, Donna S, REED, John C, KITADA, Shinichi, FLINN, Ian W, TALLMAN, Martin S, APPELBAUM, Frederick R, LARSON, Richard A

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Quantitative DNA Methylation Analysis Identifies a Single CpG Dinucleotide Important for ZAP-70 Expression and Predictive of Prognosis in Chronic Lymphocytic Leukemia von CLAUS, Rainer, LUCAS, David M, KAY, Neil E, JELINEK, Diane F, KIPPS, Thomas J, RASSENTI, Laura Z, GRIBBEN, John G, DÖHNER, Hartmut, HEEREMA, Nyla A, MARCUCCI, Guido, PLASS, Christoph, BYRD, John C, STILGENBAUER, Stephan, RUPPERT, Amy S, LIANBO YU, ZUCKNICK, Manuela, MERTENS, Daniel, BÜHLER, Andreas, OAKES, Christopher C, LARSON, Richard A

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Transducin β-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma von Youssef, Youssef, Karkhanis, Vrajesh, Chan, Wing Keung, Jeney, Frankie, Canella, Alessandro, Zhang, Xiaoli, Sloan, Shelby, Prouty, Alexander, Helmig-Mason, JoBeth, Tsyba, Liudmyla, Hanel, Walter, Zheng, Xuguang, Zhang, Pu, Chung, Ji-Hyun, Lucas, David M, Kauffman, Zachary, Larkin, Karilyn, Strohecker, Anne M, Ozer, Hatice G, Lapalombella, Rosa, Zhou, Hui, Xu-Monette, Zijun Y, Young, Ken H, Han, Ruolan, Nurmemmedov, Elmar, Nuovo, Gerard, Maddocks, Kami, Byrd, John C, Baiocchi, Robert A, Alinari, Lapo

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Select High-Risk Genetic Features Predict Earlier Progression Following Chemoimmunotherapy With Fludarabine and Rituximab in Chronic Lymphocytic Leukemia: Justification for Risk-Ad... von BYRD, John C, GRIBBEN, John G, PETERSON, Bercedis L, GREVER, Michael R, LOZANSKI, Gerard, LUCAS, David M, LAMPSON, Ben, LARSON, Richard A, CALIGIURI, Michael A, HEEREMA, Nyla A

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Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia von Papaioannou, Dimitrios, Nicolet, Deedra, Volinia, Stefano, Mrózek, Krzysztof, Yan, Pearlly, Bundschuh, Ralf, Carroll, Andrew J, Kohlschmidt, Jessica, Blum, William, Powell, Bayard L, Uy, Geoffrey L, Kolitz, Jonathan E, Wang, Eunice S, Eisfeld, Ann-Kathrin, Orwick, Shelley J, Lucas, David M, Caligiuri, Michael A, Stone, Richard M, Byrd, John C, Garzon, Ramiro, Bloomfield, Clara D

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Mcl-1 Is a Relevant Therapeutic Target in Acute and Chronic Lymphoid Malignancies: Down-Regulation Enhances Rituximab-Mediated Apoptosis and Complement-Dependent Cytotoxicity von HUSSAIN, Syed-Rehan A, CHENEY, Carolyn M, JOHNSON, Amy J, LIN, Thomas S, GREVER, Michael R, CALIGIURI, Michael A, LUCAS, David M, BYRD, John C

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The Perceptions of Math and Math Education in Midville, Illinois von Lucas, David M., Fugitt, Jamie

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Resistance to the Translation Initiation Inhibitor Silvestrol is Mediated by ABCB1/P-Glycoprotein Overexpression in Acute Lymphoblastic Leukemia Cells von Gupta, Sneha V., Sass, Ellen J., Davis, Melanie E., Edwards, Ryan B., Lozanski, Gerard, Heerema, Nyla A., Lehman, Amy, Zhang, Xiaoli, Jarjoura, David, Byrd, John C., Pan, Li, Chan, Kenneth K., Kinghorn, A. Douglas, Phelps, Mitch A., Grever, Michael R., Lucas, David M.

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Milatuzumab immunoliposomes induce cell death in CLL by promoting accumulation of CD74 on the surface of B cells von Hertlein, Erin, Triantafillou, Georgia, Sass, Ellen J., Hessler, Joshua D., Zhang, Xiaoli, Jarjoura, David, Lucas, David M., Muthusamy, Natarajan, Goldenberg, David M., Lee, Robert J., Byrd, John C.

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Pentostatin in Steroid-Refractory Acute Graft-Versus-Host Disease von BOLANOS-MEADE, Javier, JACOBSOHN, David A, VOGELSANG, Georgia B, MARGOLIS, Jeffrey, OGDEN, Adam, GUILLAUME WIENTJES, M, BYRD, John C, LUCAS, David M, ANDERS, Viki, PHELPS, Michele, GREVER, Michael R

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Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia von Alachkar, Houda, Santhanam, Ramasamy, Harb, Jason G, Lucas, David M, Oaks, Joshua J, Hickey, Christopher J, Pan, Li, Kinghorn, A Douglas, Caligiuri, Michael A, Perrotti, Danilo, Byrd, John C, Garzon, Ramiro, Grever, Michael R, Marcucci, Guido

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The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo von Lucas, David M, Alinari, Lapo, West, Derek A, Davis, Melanie E, Edwards, Ryan B, Johnson, Amy J, Blum, Kristie A, Hofmeister, Craig C, Freitas, Michael A, Parthun, Mark R, Wang, Dasheng, Lehman, Amy, Zhang, Xiaoli, Jarjoura, David, Kulp, Samuel K, Croce, Carlo M, Grever, Michael R, Chen, Ching-Shih, Baiocchi, Robert A, Byrd, John C

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Sorbicillinoid analogs with cytotoxic and selective anti-Aspergillus activities from Scytalidium album von El-Elimat, Tamam, Raja, Huzefa A, Figueroa, Mario, Swanson, Steven M, Falkinham III, Joseph O, Lucas, David M, Grever, Michael R, Wani, Mansukh C, Pearce, Cedric J, Oberlies, Nicholas H

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