Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides von Iwamoto, Naoki, Butler, David C D, Svrzikapa, Nenad, Mohapatra, Susovan, Zlatev, Ivan, Sah, Dinah W Y, Meena, Standley, Stephany M, Lu, Genliang, Apponi, Luciano H, Frank-Kamenetsky, Maria, Zhang, Jason Jingxin, Vargeese, Chandra, Verdine, Gregory L

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Regio- and Diastereoselective Insertion of Allenes into Stable Oxapalladacycles with a Metal-Bonded Stereogenic Carbon. Preparation of Contiguously Substituted 3,4-Dihydro-2H-1-Ben... von Lu, Genliang, Malinakova, Helena C

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Polymer-Supported Palladacycles:  Efficient Reagents for Synthesis of Benzopyrans with Palladium Recovery. Relationship among Resin Loading, Pd:P Ratio, and Reactivity of Immobiliz... von Hershberger, John C, Zhang, Lei, Lu, Genliang, Malinakova, Helena C

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Universal Peptidomimetics von Ko, Eunhwa, Liu, Jing, Perez, Lisa M, Lu, Genliang, Schaefer, Amber, Burgess, Kevin

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Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides von Monian, Prashant, Shivalila, Chikdu, Lu, Genliang, Shimizu, Mamoru, Boulay, David, Bussow, Karley, Byrne, Michael, Bezigian, Adam, Chatterjee, Arindom, Chew, David, Desai, Jigar, Favaloro, Frank, Godfrey, Jack, Hoss, Andrew, Iwamoto, Naoki, Kawamoto, Tomomi, Kumarasamy, Jayakanthan, Lamattina, Anthony, Lindsey, Amber, Liu, Fangjun, Looby, Richard, Marappan, Subramanian, Metterville, Jake, Murphy, Ronelle, Rossi, Jeff, Pu, Tom, Bhattarai, Bijay, Standley, Stephany, Tripathi, Snehlata, Yang, Hailin, Yin, Yuan, Yu, Hui, Zhou, Cong, Apponi, Luciano H., Kandasamy, Pachamuthu, Vargeese, Chandra

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Impact of stereopure chimeric backbone chemistries on the potency and durability of gene silencing by RNA interference von Liu, Wei, Iwamoto, Naoki, Marappan, Subramanian, Luu, Khoa, Tripathi, Snehlata, Purcell-Estabrook, Erin, Shelke, Juili Dilip, Shah, Himali, Lamattina, Anthony, Pan, Qianli, Schrand, Brett, Favaloro, Frank, Bedekar, Mugdha, Chatterjee, Arindom, Desai, Jigar, Kawamoto, Tomomi, Lu, Genliang, Metterville, Jake, Samaraweera, Milinda, Prakasha, Priyanka Shiva, Yang, Hailin, Yin, Yuan, Yu, Hui, Giangrande, Paloma H, Byrne, Michael, Kandasamy, Pachamuthu, Vargeese, Chandra

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A diversity oriented synthesis of 3′- O-modified nucleoside triphosphates for DNA ‘sequencing by synthesis’ von Lu, Genliang, Burgess, Kevin

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Rational design of base, sugar and backbone modifications improves ADAR-mediated RNA editing von Lu, Genliang, Shivalila, Chikdu, Monian, Prashant, Yu, Hui, Harding, Ian, Briem, Stearne, Byrne, Michael, Faraone, Alyse, Friend, Stephen, Huth, Olivia, Iwamoto, Naoki, Kawamoto, Tomomi, Kumarasamy, Jayakanthan, Lamattina, Anthony, Longo, Kenneth, McCarthy, Leah, McGlynn, Andrew, Molski, Allison, Pan, Qianli, Pu, Tom, Purcell-Estabrook, Erin, Rossi, Jeff, Standley, Stephany, Thomas, Carina, Walen, Alexandra, Yang, Hailin, Kandasamy, Pachamuthu, Vargeese, Chandra

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Control of backbone chemistry and chirality boost oligonucleotide splice switching activity von Kandasamy, Pachamuthu, McClorey, Graham, Shimizu, Mamoru, Kothari, Nayantara, Alam, Rowshon, Iwamoto, Naoki, Kumarasamy, Jayakanthan, Bommineni, Gopal R, Bezigian, Adam, Chivatakarn, Onanong, Butler, David C D, Byrne, Michael, Chwalenia, Katarzyna, Davies, Kay E, Desai, Jigar, Shelke, Juili Dilip, Durbin, Ann F, Ellerington, Ruth, Edwards, Ben, Godfrey, Jack, Hoss, Andrew, Liu, Fangjun, Longo, Kenneth, Lu, Genliang, Marappan, Subramanian, Oieni, Jacopo, Paik, Ik-Hyeon, Estabrook, Erin Purcell, Shivalila, Chikdu, Tischbein, Maeve, Kawamoto, Tomomi, Rinaldi, Carlo, Rajão-Saraiva, Joana, Tripathi, Snehlata, Yang, Hailin, Yin, Yuan, Zhao, Xiansi, Zhou, Cong, Zhang, Jason, Apponi, Luciano, Wood, Matthew J A, Vargeese, Chandra

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Mechanism of Stereoinduction in Asymmetric Synthesis of Highly Functionalized 1,2-Dihydroquinolines and 2H-1-Benzopyrans via Nonracemic Palladacycles with a Metal-Bonded Stereogeni... von Lu, Genliang, Malinakova, Helena C

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FRI-151 RNA editing for the treatment of Alpha-1 antitrypsin deficiency von Monian, Prashant, Lu, Genliang, Shivalila, Chikdu, Bowman, Keith, Bylsma, Marissa, Byrne, Michael, Cannon, Megan, Desai, Jigar, Faraone, Alyse, Favaloro, Frank, Ghosh, Anamitra, Godfrey, Jack, Hernandez, Nidia, Huth, Olivia, Iwamoto, Naoki, Kawamoto, Tomomi, Kumarasamy, Jayakanthan, Kandasamy, Pachamuthu, Lamattina, Anthony, Lindsey, Amber, Liu, Fangjun, Looby, Richard, Luu, Khoa, Metterville, Jake, Paik, Ik-Hyeon, Pan, Qianli, Purcell-Estabrook, Erin, Rheinhardt, Jeanette, Shimizu, Mamoru, Singh, Kuldeep, Standley, Stephany, Thomas, Carina, Tripathi, Snehlata, Yang, Hailin, Yordanoff, Ryan, Yin, Benny, Yu, Hui, Caracta, Cynthia, Narayanan, Padma, Giangrande, Paloma, Vargeese, Chandra

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Quantitative Measurement of Cytosolic and Nuclear Penetration of Oligonucleotide Therapeutics von Deprey, Kirsten, Batistatou, Nefeli, Debets, Marjoke F, Godfrey, Jack, VanderWall, Kirstin B, Miles, Rebecca R, Shehaj, Livia, Guo, Jiaxing, Andreucci, Amy, Kandasamy, Pachamuthu, Lu, Genliang, Shimizu, Mamoru, Vargeese, Chandra, Kritzer, Joshua A

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Sa1465 - The Pharmacological Properties of APOC3 Antisense Oligonucleotides are Enhanced by Control of Stereochemistry von Apponi, Luciano, Iwamoto, Naoki, Frank-Kamenetsky, Maria, Yang, Hailin, Braun, Maurine, Shah, Anee, Yin, Yuan, Butler, David, Lu, Genliang, Menon, Sethu, Standley, Stephany, Aduda, Vincent, Bowman, Keith, Longo, Kenneth, Pittet, Lynnelle, Zhang, Jason, Zhong, Zhong, Vargeese, Chandra

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An iterative route to "decorated" ethylene glycol-based linkers von Lu, Genliang, Lam, Sang, Burgess, Kevin

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Small molecule inhibitors of PSMA incorporating technetium-99m for imaging prostate cancer: Effects of chelate design on pharmacokinetics von Maresca, Kevin P., Hillier, Shawn M., Lu, Genliang, Marquis, John C., Zimmerman, Craig N., Eckelman, William C., Joyal, John L., Babich, John W.

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Novel Polar Single Amino Acid Chelates for Technetium-99m Tricarbonyl-Based Radiopharmaceuticals with Enhanced Renal Clearance: Application to Octreotide von Maresca, Kevin P, Marquis, John C, Hillier, Shawn M, Lu, Genliang, Femia, Frank J, Zimmerman, Craig N, Eckelman, William C, Joyal, John L, Babich, John W

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Synthesis and SAR of Novel Re/ 99m Tc-Labeled Benzenesulfonamide Carbonic Anhydrase IX Inhibitors for Molecular Imaging of Tumor Hypoxia von Lu, Genliang, Hillier, Shawn M., Maresca, Kevin P., Zimmerman, Craig N., Eckelman, William C., Joyal, John L., Babich, John W.

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Synthesis and SAR of Novel Re/99mTc-Labeled Benzenesulfonamide Carbonic Anhydrase IX Inhibitors for Molecular Imaging of Tumor Hypoxia von Lu, Genliang, Hillier, Shawn M, Maresca, Kevin P, Zimmerman, Craig N, Eckelman, William C, Joyal, John L, Babich, John W

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Abstract 1619: Hsp90 inhibitor drug conjugates (HDCs): Construct design and preliminary evaluation von Ying, Weiwen, Chimmanamada, Dinesh, Zhang, Junyi, Przewloka, Teresa, Jiang, Jun, Lu, Genliang, Osman, Sami, Loch, James, Vutukuri, Dharma, Chen, Shoujun, Stein, Robert, Chu, John, Proia, David, Rao, Pat, Inoue, Takayo, Ogawa, Luisa Shin, Singh, Ritu, Tatsuta, Noriaki

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sup 99m^Tc-Labeled Small-Molecule Inhibitors of Prostate-Specific Membrane Antigen for Molecular Imaging of Prostate Cancer von Hillier, Shawn M, Maresca, Kevin P, Lu, Genliang, Merkin, Ross D, Marquis, John C, Zimmerman, Craig N, Eckelman, William C, Joyal, John L, Babich, John W

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