Metabolic Contrasts Between Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: I. Observations Using the Hyperglycemic Clamp von Ehrmann, David A., Temple, Karla A., Rue, Abby, Barengolts, Elena, Mokhlesi, Babak, Van Cauter, Eve, Sam, Susan, Miller, M. Annette, Kahn, Steven E., Atkinson, Karen M., Palmer, Jerry P., Utzschneider, Kristina M., Gebremedhin, Tsige, Kernan-Schloss, Abigail, Kozedub, Alexandra, Montgomery, Brenda K., Morse, Emily J., Mather, Kieren J., Garrett, Tammy, Hannon, Tamara S., Lteif, Amale, Patel, Aniket, Chisholm, Robin, Moore, Karen, Pirics, Vivian, Pratt, Linda, Nadeau, Kristen J., Gross, Susan, Zeitler, Philip S., Williams, Jayne, Cree-Green, Melanie, Garcia Reyes, Yesenia, Vissat, Krista, Arslanian, Silva A., Brown, Kathleen, Guerra, Nancy, Porter, Kristin, Caprio, Sonia, Savoye, Mary, Pierpont, Bridget, Buchanan, Thomas A., Xiang, Anny H., Trigo, Enrique, Beale, Elizabeth, Hendee, Fadi N., Katkhouda, Namir, Nayak, Krishan, Martinez, Mayra, Montgomery, Cortney, Wang, Xinhui, Edelstein, Sharon L., Lachin, John M., Hogan, Ashley N., Marcovina, Santica, Harting, Jessica, Albers, John, Hill, Dave, Savage, Peter J., Leschek, Ellen W.

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Impact of Insulin and Metformin Versus Metformin Alone on β-Cell Function in Youth With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes von Nadeau, Kristen J., Hannon, Tamara S., Edelstein, Sharon L., Arslanian, Silva A., Caprio, Sonia, Leschek, Ellen W., Zeitler, Philip S., Buchanan, Thomas A., Ehrmann, David A., Mather, Kieren J., Kahn, Steven E., Gross, Susan, Williams, Jayne, Cree-Green, Melanie, Reyes, Yesenia Garcia, Vissat, Krista, Brown, Kathleen, Guerra, Nancy, Porter, Kristin, Savoye, Mary, Pierpont, Bridget, Garrett, Tammy, Lteif, Amale, Patel, Aniket, Chisholm, Robin, Moore, Karen, Pirics, Vivian, Pratt, Linda, Temple, Karla A., Rue, Abby, Barengolts, Elena, Mokhlesi, Babak, Van Cauter, Eve, Sam, Susan, Miller, M. Annette, Atkinson, Karen M., Palmer, Jerry P., Utzschneider, Kristina M., Gebremedhin, Tsige, Kernan-Schloss, Abigail, Kozedub, Alexandra, Montgomery, Brenda K., Morse, Emily J., Xiang, Anny H., Trigo, Enrique, Beale, Elizabeth, Hendee, Fadi N., Katkhouda, Namir, Nayak, Krishan, Martinez, Mayra, Montgomery, Cortney, Wang, Xinhui, Lachin, John M., Hogan, Ashley N., Marcovina, Santica, Harting, Jessica, Albers, John, Hill, Dave, Savage, Peter J.

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Effects of Treatment of Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes With Metformin Alone or in Combination With Insulin Glargine on β-Cell Function: Comparison... von Edelstein, Sharon L

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Metabolic Contrasts Between Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: II. Observations Using the Oral Glucose Tolerance Test von Ehrmann, David A., Temple, Karla A., Rue, Abby, Barengolts, Elena, Mokhlesi, Babak, Van Cauter, Eve, Sam, Susan, Miller, M. Annette, Kahn, Steven E., Atkinson, Karen M., Palmer, Jerry P., Utzschneider, Kristina M., Gebremedhin, Tsige, Kernan-Schloss, Abigail, Kozedub, Alexandra, Montgomery, Brenda K., Morse, Emily J., Mather, Kieren J., Garrett, Tammy, Hannon, Tamara S., Lteif, Amale, Patel, Aniket, Chisholm, Robin, Moore, Karen, Pirics, Vivian, Pratt, Linda, Nadeau, Kristen J., Gross, Susan, Zeitler, Philip S., Williams, Jayne, Green, Melanie-Cree, Garcia Reyes, Yesenia, Vissat, Krista, Arslanian, Silva A., Brown, Kathleen, Guerra, Nancy, Porter, Kristin, Caprio, Sonia, Savoye, Mary, Pierpont, Bridget, Buchanan, Thomas A., Xiang, Anny H., Trigo, Enrique, Beale, Elizabeth, Hendee, Fadi N., Katkhouda, Namir, Nayak, Krishan, Martinez, Mayra, Montgomery, Cortney, Wang, Xinhui, Edelstein, Sharon L., Lachin, John M., Hogan, Ashley N., Marcovina, Santica, Harting, Jessica, Albers, John, Hill, Dave, Savage, Peter J., Leschek, Ellen W.

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Lack of Durable Improvements in β-Cell Function Following Withdrawal of Pharmacological Interventions in Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabete... von Ehrmann, David A., Temple, Karla A., Rue, Abby, Barengolts, Elena, Mokhlesi, Babak, Van Cauter, Eve, Sam, Susan, Miller, M. Annette, Kahn, Steven E., Atkinson, Karen M., Palmer, Jerry P., Utzschneider, Kristina M., Gebremedhin, Tsige, Kernan-Schloss, Abigail, Kozedub, Alexandra, Montgomery, Brenda K., Morse, Emily J., Mather, Kieren J., Garrett, Tammy, Hannon, Tamara S., Lteif, Amale, Patel, Aniket, Chisholm, Robin, Moore, Karen, Pirics, Vivian, Pratt, Linda, Nadeau, Kristen J., Gross, Susan, Zeitler, Philip S., Williams, Jayne, Cree-Green, Melanie, Garcia Reyes, Yesenia, Vissat, Krista, Arslanian, Silva A., Brown, Kathleen, Guerra, Nancy, Porter, Kristin, Caprio, Sonia, Savoye, Mary, Pierpont, Bridget, Buchanan, Thomas A., Xiang, Anny H., Trigo, Enrique, Beale, Elizabeth, Chow, Ting, Hendee, Fadi N., Katkhouda, Namir, Nayak, Krishan, Martinez, Mayra, Montgomery, Cortney, Wang, Xinhui, Wu, Jun, Edelstein, Sharon L., Lachin, John M., Tjaden, Ashley Hogan, Marcovina, Santica, Harting, Jessica, Albers, John, Hill, Dave, Savage, Peter J., Leschek, Ellen W.

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Association of Self-Reported Sleep and Circadian Measures With Glycemia in Adults With Prediabetes or Recently Diagnosed Untreated Type 2 Diabetes von Mokhlesi, Babak, Temple, Karla A, Tjaden, Ashley H, Edelstein, Sharon L, Utzschneider, Kristina M, Nadeau, Kristen J, Hannon, Tamara S, Sam, Susan, Barengolts, Elena, Manchanda, Shalini, Ehrmann, David A, Van Cauter, Eve

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Comparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes: The GRADE Randomized Clinical Trial von Wexler, Deborah J, de Boer, Ian H, Ghosh, Alokananda, Younes, Naji, Bebu, Ionut, Inzucchi, Silvio E, McGill, Janet B, Mudaliar, Sunder, Schade, David, Steffes, Michael W, Tamborlane, William V, Tan, Meng H, Ismail-Beigi, Faramarz

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Baseline Predictors of Glycemic Worsening in Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study von Sam, Susan, Edelstein, Sharon L, Arslanian, Silva A, Barengolts, Elena, Buchanan, Thomas A, Caprio, Sonia, Ehrmann, David A, Hannon, Tamara S, Tjaden, Ashley Hogan, Kahn, Steven E, Mather, Kieren J, Tripputi, Mark, Utzschneider, Kristina M, Xiang, Anny H, Nadeau, Kristen J

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Baseline Characteristics of Randomized Participants in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) von Wexler, Deborah J, Krause-Steinrauf, Heidi, Crandall, Jill P, Florez, Hermes J, Hox, Sophia H, Kuhn, Alexander, Sood, Ajay, Underkofler, Chantal, Aroda, Vanita R

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OGTT Glucose Response Curves, Insulin Sensitivity, and β-Cell Function in RISE: Comparison Between Youth and Adults at Randomization and in Response to Interventions to Preserve β-... von Arslanian, Silva A, El Ghormli, Laure, Kim, Joon Young, Tjaden, Ashley H, Barengolts, Elena, Caprio, Sonia, Hannon, Tamara S, Mather, Kieren J, Nadeau, Kristen J, Utzschneider, Kristina M, Kahn, Steven E

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Obstructive Sleep Apnea, Glucose Tolerance, and β-Cell Function in Adults With Prediabetes or Untreated Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study von Mokhlesi, Babak, Tjaden, Ashley H, Temple, Karla A, Edelstein, Sharon L, Sam, Susan, Nadeau, Kristen J, Hannon, Tamara S, Manchanda, Shalini, Mather, Kieren J, Kahn, Steven E, Ehrmann, David A, Van Cauter, Eve

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Role of Endogenous ET-1 in the Regulation of Myocardial Blood Flow in Lean and Obese Humans von Mather, Kieren J, Lteif, Amale A, Veeneman, Emily, Fain, Richard, Giger, Susan, Perry, Kevin, Hutchins, Gary D

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Impact of Gastric Banding Versus Metformin on β-Cell Function in Adults With Impaired Glucose Tolerance or Mild Type 2 Diabetes von Xiang, Anny H, Trigo, Enrique, Martinez, Mayra, Katkhouda, Namir, Beale, Elizabeth, Wang, Xinhui, Wu, Jun, Chow, Ting, Montgomery, Cortney, Nayak, Krishna S, Hendee, Fadi, Buchanan, Thomas A

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Association of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Coh... von Rasouli, Neda, Younes, Naji, Utzschneider, Kristina M, Inzucchi, Silvio E, Balasubramanyam, Ashok, Cherrington, Andrea L, Ismail-Beigi, Faramarz, Cohen, Robert M, Olson, Darin E, DeFronzo, Ralph A, Herman, William H, Lachin, John M, Kahn, Steven E

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Hyperglucagonemia Does Not Explain the β-Cell Hyperresponsiveness and Insulin Resistance in Dysglycemic Youth Compared With Adults: Lessons From the RISE Study von Kahn, Steven E, Mather, Kieren J, Arslanian, Silva A, Barengolts, Elena, Buchanan, Thomas A, Caprio, Sonia, Ehrmann, David A, Hannon, Tamara S, Marcovina, Santica, Nadeau, Kristen J, Utzschneider, Kristina M, Xiang, Anny H, Edelstein, Sharon L

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Lanthanum Carbonate Interference With Lumbar Spine DXA von Walsh, James P, Lteif, Amale A

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Optimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight von Sivitz, William I, Phillips, Lawrence S, Wexler, Deborah J, Fortmann, Stephen P, Camp, Anne W, Tiktin, Margaret, Perez, Magalys, Craig, Jacqueline, Hollander, Priscilla A, Cherrington, Andrea, Aroda, Vanita R, Tan, Meng Hee, Krakoff, Jonathan, Rasouli, Neda, Butera, Nicole M, Younes, Naji

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Association of Glycemia, Lipids, and Blood Pressure With Cognitive Performance in People With Type 2 Diabetes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effect... von Luchsinger, José A, Younes, Naji, Manly, Jennifer J, Barzilay, Joshua, Valencia, Willy, Larkin, Mary E, Falck-Ytter, Corinna, Krause-Steinrauf, Heidi, Pop-Busui, Rodica, Florez, Hermes, Seaquist, Elizabeth

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Precision and accuracy of hyperglycemic clamps in a multicenter study von Mather, Kieren J, Tjaden, Ashley H, Hoehn, Adam, Nadeau, Kristen J, Buchanan, Thomas A, Kahn, Steven E, Arslanian, Silva A, Caprio, Sonia, Atkinson, Karen M, Cree-Green, Melanie, Utzschneider, Kristina M, Edelstein, Sharon L

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Effect of Medical and Surgical Interventions on α-Cell Function in Dysglycemic Youth and Adults in the RISE Study von Kahn, Steven E, Edelstein, Sharon L, Arslanian, Silva A, Barengolts, Elena, Caprio, Sonia, Ehrmann, David A, Hannon, Tamara S, Marcovina, Santica, Mather, Kieren J, Nadeau, Kristen J, Utzschneider, Kristina M, Xiang, Anny H, Buchanan, Thomas A

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