Current approaches to fine mapping of antigen–antibody interactions von Abbott, W. Mark, Damschroder, Melissa M., Lowe, David C.

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An in vivo platform to select and evolve aggregation-resistant proteins von Ebo, Jessica S., Saunders, Janet C., Devine, Paul W. A., Gordon, Alice M., Warwick, Amy S., Schiffrin, Bob, Chin, Stacey E., England, Elizabeth, Button, James D., Lloyd, Christopher, Bond, Nicholas J., Ashcroft, Alison E., Radford, Sheena E., Lowe, David C., Brockwell, David J.

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Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS von Devine, Paul W. A., Fisher, Henry C., Calabrese, Antonio N., Whelan, Fiona, Higazi, Daniel R., Potts, Jennifer R., Lowe, David C., Radford, Sheena E., Ashcroft, Alison E.

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Inducing protein aggregation by extensional flow von Dobson, John, Kumar, Amit, Willis, Leon F., Tuma, Roman, Higazi, Daniel R., Turner, Richard, Lowe, David C., Ashcroft, Alison E., Radford, Sheena E., Kapur, Nikil, Brockwell, David J.

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Short-term variations in the oxidizing power of the atmosphere von Manning, Martin R, Lowe, David C, Moss, Rowena C, Bodeker, Gregory E, Allan, William

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Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation von Cohen, E. Suzanne, Scott, Ian C., Majithiya, Jayesh B., Rapley, Laura, Kemp, Benjamin P., England, Elizabeth, Rees, D. Gareth, Overed-Sayer, Catherine L., Woods, Joanne, Bond, Nicholas J., Veyssier, Christel Séguy, Embrey, Kevin J., Sims, Dorothy A., Snaith, Michael R., Vousden, Katherine A., Strain, Martin D., Chan, Denice T. Y., Carmen, Sara, Huntington, Catherine E., Flavell, Liz, Xu, Jianqing, Popovic, Bojana, Brightling, Christopher E., Vaughan, Tristan J., Butler, Robin, Lowe, David C., Higazi, Daniel R., Corkill, Dominic J., May, Richard D., Sleeman, Matthew A., Mustelin, Tomas

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Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction von England, Elizabeth, Rees, D. Gareth, Scott, Ian Christopher, Carmen, Sara, Chan, Denice T. Y., Chaillan Huntington, Catherine E., Houslay, Kirsty F., Erngren, Teodor, Penney, Mark, Majithiya, Jayesh B., Rapley, Laura, Sims, Dorothy A., Hollins, Claire, Hinchy, Elizabeth C., Strain, Martin D., Kemp, Benjamin P., Corkill, Dominic J., May, Richard D., Vousden, Katherine A., Butler, Robin J., Mustelin, Tomas, Vaughan, Tristan J., Lowe, David C., Colley, Caroline, Cohen, E. Suzanne

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Global change A green source of surprise von Lowe, David C

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Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo von Dobson, Claire L., Devine, Paul W. A., Phillips, Jonathan J., Higazi, Daniel R., Lloyd, Christopher, Popovic, Bojana, Arnold, Joanne, Buchanan, Andrew, Lewis, Arthur, Goodman, Joanne, van der Walle, Christopher F., Thornton, Peter, Vinall, Lisa, Lowne, David, Aagaard, Anna, Olsson, Lise-Lotte, Ridderstad Wollberg, Anna, Welsh, Fraser, Karamanos, Theodoros K., Pashley, Clare L., Iadanza, Matthew G., Ranson, Neil A., Ashcroft, Alison E., Kippen, Alistair D., Vaughan, Tristan J., Radford, Sheena E., Lowe, David C.

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Rituximab causes a polarization of B cells that augments its therapeutic function in NK-cell–mediated antibody-dependent cellular cytotoxicity von Rudnicka, Dominika, Oszmiana, Anna, Finch, Donna K., Strickland, Ian, Schofield, Darren J., Lowe, David C., Sleeman, Matthew A., Davis, Daniel M.

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Global and Local Conformation of Human IgG Antibody Variants Rationalizes Loss of Thermodynamic Stability von Edgeworth, Matthew J., Phillips, Jonathan J., Lowe, David C., Kippen, Alistair D., Higazi, Daniel R., Scrivens, James H.

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Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1 von Vousden, Katherine A., Lundqvist, Tomas, Popovic, Bojana, Naiman, Brian, Carruthers, Alan M., Newton, Philip, Johnson, Daniel J. D., Pomowski, Anja, Wilkinson, Trevor, Dufner, Patrick, de Mendez, Isabelle, Mallinder, Philip R., Murray, Clare, Strain, Martin, Connor, Jane, Murray, Lynne A., Sleeman, Matthew A., Lowe, David C., Huntington, James A., Vaughan, Tristan J.

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Variability in atmospheric O2 and CO2 concentrations in the southern Pacific Ocean and their comparison with model estimates von Thompson, Rona L., Gloor, Manuel, Manning, Andrew C., Lowe, David C., Rödenbeck, Christian, Le Quéré, Corinne

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Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1 von Douthwaite, Julie A, Sridharan, Sudharsan, Huntington, Catherine, Hammersley, Jayne, Marwood, Rose, Hakulinen, Jonna K, Ek, Margareta, Sjögren, Tove, Rider, David, Privezentzev, Cyril, Seaman, Jonathan C, Cariuk, Peter, Knights, Vikki, Young, Joyce, Wilkinson, Trevor, Sleeman, Matthew, Finch, Donna K, Lowe, David C, Vaughan, Tristan J

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Whole-Molecule Antibody Engineering: Generation of a High-Affinity Anti-IL-6 Antibody with Extended Pharmacokinetics von Finch, Donna K., Sleeman, Matthew A., Moisan, Jacques, Ferraro, Franco, Botterell, Sara, Campbell, Jamie, Cochrane, Duncan, Cruwys, Simon, England, Elizabeth, Lane, Steven, Rendall, Elizabeth, Sinha, Monisha, Walker, Craig, Rees, Gareth, Bowen, Michael A., Schneider, Amy, Liang, Meina, Faggioni, Raffaella, Fung, Michael, Mallinder, Philip R., Wilkinson, Trevor, Kolbeck, Roland, Vaughan, Tristan, Lowe, David C.

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Affinity maturation of a novel antagonistic human monoclonal antibody with a long V H CDR3 targeting the Class A GPCR formyl-peptide receptor 1 von Douthwaite, Julie A, Sridharan, Sudharsan, Huntington, Catherine, Hammersley, Jayne, Marwood, Rose, Hakulinen, Jonna K, Ek, Margareta, Sjögren, Tove, Rider, David, Privezentzev, Cyril, Seaman, Jonathan C, Cariuk, Peter, Knights, Vikki, Young, Joyce, Wilkinson, Trevor, Sleeman, Matthew, Finch, Donna K, Lowe, David C, Vaughan, Tristan J

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The INNs and outs of antibody nonproprietary names von Jones, Tim D., Carter, Paul J., Plückthun, Andreas, Vásquez, Max, Holgate, Robert G.E., Hötzel, Isidro, Popplewell, Andrew G., Parren, Paul W.H.I., Enzelberger, Markus, Rademaker, Hendrik J., Clark, Michael R., Lowe, David C., Dahiyat, Bassil I., Smith, Victoria, Lambert, John M., Wu, Herren, Reilly, Mary, Haurum, John S., Dübel, Stefan, Huston, James S., Schirrmann, Thomas, Janssen, Richard A.J., Steegmaier, Martin, Gross, Jane A., Bradbury, Andrew R.M., Burton, Dennis R., Dimitrov, Dimiter S., Chester, Kerry A., Glennie, Martin J., Davies, Julian, Walker, Adam, Martin, Steve, McCafferty, John, Baker, Matthew P.

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A comparison of the ability of the human IgG1 allotypes G1m3 and G1m1,17 to stimulate T-cell responses from allotype matched and mismatched donors von Webster, Carl I, Bryson, Christine J, Cloake, Edward A, Jones, Tim D, Austin, Mark J, Karle, Anette C, Spindeldreher, Sebastian, Lowe, David C, Baker, Matthew P

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Engineering a High-Affinity Anti-IL-15 Antibody: Crystal Structure Reveals an α-Helix in VH CDR3 as Key Component of Paratope von Lowe, David C., Gerhardt, Stefan, Ward, Alison, Hargreaves, David, Anderson, Malcolm, Ferraro, Franco, Pauptit, Richard A., Pattison, Debbie V., Buchanan, Catriona, Popovic, Bojana, Finch, Donna K., Wilkinson, Trevor, Sleeman, Matthew, Vaughan, Tristan J., Mallinder, Philip R.

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Seasonal cycles of mixing ratio and 13C in atmospheric methane at Suva, Fiji von Lowe, David C., Koshy, Kanayathu, Bromley, Tony, Allan, W., Struthers, H., Mani, F., Maata, M.

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