Bendamustine (Treanda) Displays a Distinct Pattern of Cytotoxicity and Unique Mechanistic Features Compared with Other Alkylating Agents von LEONI, Lorenzo M, BAILEY, Brandi, REIFERT, Jack, BENDALL, Heather H, ZELLER, Robert W, CORBEIL, Jacques, ELLIOTT, Gary, NIEMEYER, Christina C

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Activation of the Wnt Signaling Pathway in Chronic Lymphocytic Leukemia von Lu, Desheng, Zhao, Yandong, Tawatao, Rommel, Cottam, Howard B., Sen, Malini, Leoni, Lorenzo M., Kipps, Thomas J., Corr, Maripat, Carson, Dennis A.

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Mechanism of Action: The Unique Pattern of Bendamustine-Induced Cytotoxicity von Leoni, Lorenzo M, Hartley, John A

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Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria von Genini, Davide, Adachi, Souichi, Chao, Qi, Rose, David W., Carrera, Carlos J., Cottam, Howard B., Carson, Dennis A., Leoni, Lorenzo M.

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Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1 von Pedersen, Irene M., Kitada, Shinichi, Leoni, Lorenzo M., Zapata, Juan M., Karras, James G., Tsukada, Nobuhiro, Kipps, Thomas J., Choi, Yong Sung, Bennett, Frank, Reed, John C.

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Bendamustine: Rescue of an Effective Antineoplastic Agent From the Mid-Twentieth Century von Leoni, Lorenzo M

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Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion von Hustinx, Steven R, Leoni, Lorenzo M, Yeo, Charles J, Brown, Priscilla N, Goggins, Michael, Kern, Scott E, Hruban, Ralph H, Maitra, Anirban

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The R-Enantiomer of the Nonsteroidal Antiinflammatory Drug Etodolac Binds Retinoid X Receptor and Induces Tumor-Selective Apoptosis von Kolluri, Siva Kumar, Corr, Maripat, James, Sharon Y., Bernasconi, Michele, Lu, Desheng, Liu, Wen, Cottam, Howard B., Leoni, Lorenzo M., Carson, Dennis A., Zhang, Xiao-kun

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SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma von Yasui, Hiroshi, Hideshima, Teru, Hamasaki, Makoto, Roccaro, Aldo M., Shiraishi, Norihiko, Kumar, Shaji, Tassone, Pierfrancesco, Ishitsuka, Kenji, Raje, Noopur, Tai, Yu-Tzu, Podar, Klaus, Chauhan, Dharminder, Leoni, Lorenzo M., Kanekal, Sarath, Elliott, Gary, Munshi, Nikhil C., Anderson, Kenneth C.

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Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers von Karikari, Collins A, Mullendore, Michael, Eshleman, James R, Argani, Pedram, Leoni, Lorenzo M, Chattopadhyay, Shrikanta, Hidalgo, Manuel, Maitra, Anirban

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Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: A potential new target for therapy von Hustinx, Steven R., Hruban, Ralph H., Leoni, Lorenzo M., Iacobuzio-Donahue, Christine, Cameron, John L., Yeo, Charles J., Brown, Priscilla N., Argani, Pedram, Ashfaq, Raheela, Fukushima, Noriyoshi, Goggins, Michael, Kern, Scott E., Maitra, Anirban

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The Evolving Role of Bendamustine in Lymphoid Malignancy: Understanding the Drug and Its Mechanism of Action—Introduction von Leoni, Lorenzo M

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Induction of an Apoptotic Program in Cell-Free Extracts by 2-Chloro-2′-deoxyadenosine 5′-Triphosphate and Cytochrome c von Leoni, Lorenzo M., Chao, Qi, Cottam, Howard B., Genini, Davide, Rosenbach, Michael, Carrera, Carlos J., Budihardjo, Imawati, Wang, Xiaodong, Carson, Dennis A.

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Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis von Rachmilewitz, Daniel, Karmeli, Fanny, Takabayashi, Kenji, Hayashi, Tomoko, Leider-Trejo, Leonor, Lee, Jongdae, Leoni, Lorenzo M., Raz, Eyal

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Conclusion and Future Directions von Leoni, Lorenzo M

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Substituted Isoquinolines and Quinazolines as Potential Antiinflammatory Agents. Synthesis and Biological Evaluation of Inhibitors of Tumor Necrosis Factor α von Chao, Qi, Deng, Lynn, Shih, Hsiencheng, Leoni, Lorenzo M, Genini, Davide, Carson, Dennis A, Cottam, Howard B

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Nucleotide Requirements for the in Vitro Activation of the Apoptosis Protein-activating Factor-1-mediated Caspase Pathway von Genini, D, Budihardjo, I, Plunkett, W, Wang, X, Carrera, C J, Cottam, H B, Carson, D A, Leoni, L M

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A New Reporter Cell Line to Monitor HIV Infection and Drug Susceptibility in vitro von Gervaix, Alain, West, Daniel, Leoni, Lorenzo M., Richman, Douglas D., Wong-Staal, Flossie, Corbeil, Jacques

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Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells von LEONI, L. M, HAMEL, E, GENINI, D, SHIH, H, CARRERA, C. J, COTTAM, H. B, CARSON, D. A

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Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP von Balakrishnan, Kumudha, Stellrecht, Christine M., Genini, Davide, Ayres, Mary, Wierda, William G., Keating, Michael J., Leoni, Lorenzo M., Gandhi, Varsha

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