Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells von Romagnoli, Romeo, Prencipe, Filippo, Lopez-Cara, Luisa Carlota, Oliva, Paola, Baraldi, Stefania, Baraldi, Pier Giovanni, Estévez-Sarmiento, Francisco, Quintana, José, Estévez, Francisco

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Targeting Aryl hydrocarbon receptor for next-generation immunotherapies: Selective modulators (SAhRMs) versus rapidly metabolized ligands (RMAhRLs) von Dolciami, Daniela, Ballarotto, Marco, Gargaro, Marco, López-Cara, Luisa Carlota, Fallarino, Francesca, Macchiarulo, Antonio

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Design, Synthesis, and Biological Evaluation of 6‑Substituted Thieno[3,2‑d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors von Romagnoli, Romeo, Prencipe, Filippo, Oliva, Paola, Baraldi, Stefania, Baraldi, Pier Giovanni, Schiaffino Ortega, Santiago, Chayah, Mariem, Kimatrai Salvador, Maria, Lopez-Cara, Luisa Carlota, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Ronca, Roberto, Bortolozzi, Roberta, Mariotto, Elena, Mattiuzzo, Elena, Viola, Giampietro

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3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine von Clement, Cristina C., D’Alessandro, Angelo, Thangaswamy, Sangeetha, Chalmers, Samantha, Furtado, Raquel, Spada, Sheila, Mondanelli, Giada, Ianni, Federica, Gehrke, Sarah, Gargaro, Marco, Manni, Giorgia, Cara, Luisa Carlota Lopez, Runge, Peter, Tsai, Wanxia Li, Karaman, Sinem, Arasa, Jorge, Fernandez-Rodriguez, Ruben, Beck, Amanda, Macchiarulo, Antonio, Gadina, Massimo, Halin, Cornelia, Fallarino, Francesca, Skobe, Mihaela, Veldhoen, Marc, Moretti, Simone, Formenti, Silvia, Demaria, Sandra, Soni, Rajesh K., Galarini, Roberta, Sardella, Roccaldo, Lauvau, Gregoire, Putterman, Chaim, Alitalo, Kari, Grohmann, Ursula, Santambrogio, Laura

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EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells von Mariotto, Elena, Bortolozzi, Roberta, Volpin, Ilaria, Carta, Davide, Serafin, Valentina, Accordi, Benedetta, Basso, Giuseppe, Navarro, Pilar Luque, López-Cara, Luisa Carlota, Viola, Giampietro

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New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action von Luque-Navarro, Pilar M., Carrasco-Jiménez, M. Paz, Goracci, Laura, Paredes, Jose M., Espinar-Barranco, Laura, Valverde-Pozo, Javier, Torretta, Archimede, Parisini, Emilio, Mariotto, Elena, Marchioro, Chiara, Laso, Alejandro, Marco, Carmen, Viola, Giampietro, Lanari, Daniela, López Cara, Luisa Carlota

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Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imidazole von Romagnoli, Romeo, Baraldi, Pier Giovanni, Prencipe, Filippo, Oliva, Paola, Baraldi, Stefania, Tabrizi, Mojgan Aghazadeh, Lopez-Cara, Luisa Carlota, Ferla, Salvatore, Brancale, Andrea, Hamel, Ernest, Ronca, Roberto, Bortolozzi, Roberta, Mariotto, Elena, Basso, Giuseppe, Viola, Giampietro

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Crystal Structure of the Apo and the ADP-Bound Form of Choline Kinase from Plasmodium falciparum von Torretta, Archimede, Lopez-Cara, Luisa Carlota, Parisini, Emilio

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Synthesis, biological evaluation, in silico modeling and crystallization of novel small monocationic molecules with potent antiproliferative activity by dual mechanism von Serrán- Aguilera, Lucía, Mariotto, Elena, Rubbini, Gianluca, Castro Navas, Francisco Fermín, Marco, Carmen, Carrasco-Jiménez, María Paz, Ballarotto, Marco, Macchiarulo, Antonio, Hurtado-Guerrero, Ramón, Viola, Giampietro, Lopez-Cara, Luisa Carlota

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2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition von Romagnoli, Romeo, Kimatrai Salvador, Maria, Schiaffino Ortega, Santiago, Baraldi, Pier Giovanni, Oliva, Paola, Baraldi, Stefania, Lopez-Cara, Luisa Carlota, Brancale, Andrea, Ferla, Salvatore, Hamel, Ernest, Balzarini, Jan, Liekens, Sandra, Mattiuzzo, Elena, Basso, Giuseppe, Viola, Giampietro

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Biological Evaluation of New Thienopyridinium and Thienopyrimidinium Derivatives as Human Choline Kinase Inhibitors von Luque-Navarro, Pilar María, Mariotto, Elena, Ballarotto, Marco, Rubbini, Gianluca, Aguilar-Troyano, Francisco José, Fasiolo, Alberto, Torretta, Archimede, Parisini, Emilio, Macchiarulo, Antonio, Laso, Alejandro, Marco, Carmen, Viola, Giampietro, Carrasco-Jimenez, María Paz, López-Cara, Luisa Carlota

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Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors von Schiaffino-Ortega, Santiago, Mariotto, Elena, Luque-Navarro, Pilar María, Kimatrai-Salvador, María, Rios-Marco, Pablo, Hurtado-Guerrero, Ramon, Marco, Carmen, Carrasco-Jimenez, María Paz, Viola, Giampietro, López-Cara, Luisa Carlota

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1H and 13C NMR spectral assignments of 1,1′-(((ethane-1,2-diylbis(oxy))bis(4,1-phenylene))bis(methylene))-bispyridinium and -bisquinolinium bromide derivatives von Schiaffino-Ortega, Santiago, Kimatrai-Salvador, María, Baglioni, Eleonora, Gallo, Miguel Angel, Entrena Guadix, Antonio, Lopez-Cara, Luisa Carlota

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New Compounds with Bioisosteric Replacement of Classic Choline Kinase Inhibitors Show Potent Antiplasmodial Activity von Aguilar-Troyano, Francisco José, Torretta, Archimede, Rubbini, Gianluca, Fasiolo, Alberto, Luque-Navarro, Pilar María, Carrasco-Jimenez, María Paz, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, González-Pacanowska, Dolores, Parisini, Emilio, Lopez-Cara, Luisa Carlota

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Choline Kinase Alpha Inhibition by EB-3D Triggers Cellular Senescence, Reduces Tumor Growth and Metastatic Dissemination in Breast Cancer von Mariotto, Elena, Viola, Giampietro, Ronca, Roberto, Persano, Luca, Aveic, Sanja, Bhujwalla, Zaver M, Mori, Noriko, Accordi, Benedetta, Serafin, Valentina, López-Cara, Luisa Carlota, Bortolozzi, Roberta

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Synthesis and Biological Evaluation of Novel 1-Deoxy-1-[6-[((hetero)arylcarbonyl)hydrazino]- 9H-purin-9-yl]-N-ethyl-β-d-ribofuranuronamide Derivatives as Useful Templates for the D... von Baraldi, Pier Giovanni, Preti, Delia, Tabrizi, Mojgan Aghazadeh, Fruttarolo, Francesca, Romagnoli, Romeo, Carrion, Maria Dora, Cara, Luisa Carlota Lopez, Moorman, Allan R., Varani, Katia, Borea, Pier Andrea

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Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1) von Schiaffino-Ortega, Santiago, Baglioni, Eleonora, Mariotto, Elena, Bortolozzi, Roberta, Serrán-Aguilera, Lucía, Ríos-Marco, Pablo, Carrasco-Jimenez, M. Paz, Gallo, Miguel A., Hurtado-Guerrero, Ramon, Marco, Carmen, Basso, Giuseppe, Viola, Giampietro, Entrena, Antonio, López-Cara, Luisa Carlota

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1,2-Diphenoxiethane salts as potent antiplasmodial agents von Schiafino-Ortega, Santiago, Baglioni, Eleonora, Pérez-Moreno, Guiomar, Marco, Pablo Rios, Marco, Carmen, González-Pacanowska, Dolores, Ruiz-Pérez, Luis Miguel, Carrasco-Jiménez, María Paz, López-Cara, Luisa Carlota

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Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents von Romagnoli, Romeo, Baraldi, Pier Giovanni, Prencipe, Filippo, Oliva, Paola, Baraldi, Stefania, Salvador, Maria Kimatrai, Lopez-Cara, Luisa Carlota, Bortolozzi, Roberta, Mattiuzzo, Elena, Basso, Giuseppe, Viola, Giampietro

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New non-symmetrical choline kinase inhibitors von Schiaffino-Ortega, Santiago, López-Cara, Luisa Carlota, Ríos-Marco, Pablo, Carrasco-Jimenez, Maria Paz, Gallo, Miguel A., Espinosa, Antonio, Marco, Carmen, Entrena, Antonio

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