Population-Based Penetrance of Deleterious Clinical Variants von Forrest, Iain S, Chaudhary, Kumardeep, Vy, Ha My T, Petrazzini, Ben O, Bafna, Shantanu, Jordan, Daniel M, Rocheleau, Ghislain, Loos, Ruth J. F, Nadkarni, Girish N, Cho, Judy H, Do, Ron

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The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population von Chami, Nathalie, Preuss, Michael, Walker, Ryan W, Moscati, Arden, Loos, Ruth J F

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Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study von Li, Shengxu, Zhao, Jing Hua, Luan, Jian'an, Ekelund, Ulf, Luben, Robert N, Khaw, Kay-Tee, Wareham, Nicholas J, Loos, Ruth J F

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15 years of genome-wide association studies and no signs of slowing down von Loos, Ruth J. F.

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Clinical Characterization of Copy Number Variants Associated With Neurodevelopmental Disorders in a Large-scale Multiancestry Biobank von Birnbaum, Rebecca, Mahjani, Behrang, Loos, Ruth J. F, Sharp, Andrew J

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The genetics of obesity: from discovery to biology von Loos, Ruth J. F., Yeo, Giles S. H.

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Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity von Dallner, Olof S., Marinis, Jill M., Lu, Yi-Hsueh, Birsoy, Kivanc, Werner, Emory, Fayzikhodjaeva, Gulya, Dill, Brian D., Molina, Henrik, Moscati, Arden, Kutalik, Zoltán, Marques-Vidal, Pedro, Kilpeläinen, Tuomas O., Grarup, Niels, Linneberg, Allan, Zhang, Yinxin, Vaughan, Roger, Loos, Ruth J. F., Lazar, Mitchell A., Friedman, Jeffrey M.

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Correlates of physical activity: why are some people physically active and others not? von Bauman, Adrian E, Prof, Reis, Rodrigo S, Prof, Sallis, James F, Prof, Wells, Jonathan C, Prof, Loos, Ruth JF, Prof, Martin, Brian W, MD

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Eating behavior trajectories in the first 10 years of life and their relationship with BMI von Herle, Moritz, Stavola, Bianca De, Hübel, Christopher, Ferreira, Diana L. Santos, Abdulkadir, Mohamed, Yilmaz, Zeynep, Loos, Ruth J. F., Bryant-Waugh, Rachel, Bulik, Cynthia M., Micali, Nadia

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Genomics and phenomics of body mass index reveals a complex disease network von Huang, Jie, Huffman, Jennifer E., Huang, Yunfeng, Do Valle, Ítalo, Assimes, Themistocles L., Raghavan, Sridharan, Voight, Benjamin F., Liu, Chang, Barabási, Albert-László, Huang, Rose D. L., Hui, Qin, Nguyen, Xuan-Mai T., Ho, Yuk-Lam, Djousse, Luc, Lynch, Julie A., Vujkovic, Marijana, Tcheandjieu, Catherine, Tang, Hua, Damrauer, Scott M., Reaven, Peter D., Miller, Donald, Phillips, Lawrence S., Ng, Maggie C. Y., Graff, Mariaelisa, Haiman, Christopher A., Loos, Ruth J. F., North, Kari E., Yengo, Loic, Smith, George Davey, Saleheen, Danish, Gaziano, J. Michael, Rader, Daniel J., Tsao, Philip S., Cho, Kelly, Chang, Kyong-Mi, Wilson, Peter W. F., Sun, Yan V., O’Donnell, Christopher J.

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Prognostic value of polygenic risk scores for adults with psychosis von Landi, Isotta, Kaji, Deepak A., Cotter, Liam, Van Vleck, Tielman, Belbin, Gillian, Preuss, Michael, Loos, Ruth J. F., Kenny, Eimear, Glicksberg, Benjamin S., Beckmann, Noam D., O’Reilly, Paul, Schadt, Eric E., Achtyes, Eric D., Buckley, Peter F., Lehrer, Douglas, Malaspina, Dolores P., McCarroll, Steven A., Rapaport, Mark H., Fanous, Ayman H., Pato, Michele T., Pato, Carlos N., Bigdeli, Tim B., Nadkarni, Girish N., Charney, Alexander W.

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Heritability of objectively assessed daily physical activity and sedentary behavior von Hoed, Marcel den, Brage, Søren, Zhao, Jing Hua, Westgate, Kate, Nessa, Ayrun, Ekelund, Ulf, Spector, Tim D, Wareham, Nicholas J, Loos, Ruth JF

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A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood von Kurniansyah, Nuzulul, Goodman, Matthew O., Kelly, Tanika N., Elfassy, Tali, Wiggins, Kerri L., Bis, Joshua C., Guo, Xiuqing, Palmas, Walter, Taylor, Kent D., Lin, Henry J., Haessler, Jeffrey, Gao, Yan, Shimbo, Daichi, Smith, Jennifer A., Yu, Bing, Feofanova, Elena V., Smit, Roelof A. J., Wang, Zhe, Hwang, Shih-Jen, Liu, Simin, Wassertheil-Smoller, Sylvia, Manson, JoAnn E., Lloyd-Jones, Donald M., Rich, Stephen S., Loos, Ruth J. F., Redline, Susan, Correa, Adolfo, Kooperberg, Charles, Fornage, Myriam, Kaplan, Robert C., Psaty, Bruce M., Rotter, Jerome I., Arnett, Donna K., Morrison, Alanna C., Franceschini, Nora, Levy, Daniel, Sofer, Tamar

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Associations between common variants in GC and DHCR7/NADSYN1 and vitamin D concentration in Chinese Hans von Lu, Ling, Sheng, Hongguang, Li, Huaixing, Gan, Wei, Liu, Chen, Zhu, Jingwen, Loos, Ruth J. F., Lin, Xu

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Common Variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE Genes Are Associated With Type 2 Diabetes and Impaired Fasting Glucose in a Chinese Han Population von YING WU, HUAIXING LI, LOOS, Ruth J. F, ZHIJIE YU, XINGWANG YE, LIHUA CHEN, AN PAN, HU, Frank B, XU LIN

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The genetic epidemiology of melanocortin 4 receptor variants von Loos, Ruth J.F.

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Implementing genomic screening in diverse populations von Abul-Husn, Noura S, Soper, Emily R, Braganza, Giovanna T, Rodriguez, Jessica E, Zeid, Natasha, Cullina, Sinead, Bobo, Dean, Moscati, Arden, Merkelson, Amanda, Loos, Ruth J F, Cho, Judy H, Belbin, Gillian M, Suckiel, Sabrina A, Kenny, Eimear E

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Trend in obesity prevalence in European adult cohort populations during follow-up since 1996 and their predictions to 2015 von von Ruesten, Anne, Steffen, Annika, Floegel, Anna, van der A, Daphne L, Masala, Giovanna, Tjønneland, Anne, Halkjaer, Jytte, Palli, Domenico, Wareham, Nicholas J, Loos, Ruth J F, Sørensen, Thorkild I A, Boeing, Heiner

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Life course variations in the associations between FTO and MC4R gene variants and body size von Hardy, Rebecca, Wills, Andrew K., Wong, Andrew, Elks, Cathy E., Wareham, Nicholas J., Loos, Ruth J.F., Kuh, Diana, Ong, Ken K.

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Variants in the Fat Mass–and Obesity-Associated (FTO) Gene Are Not Associated With Obesity in a Chinese Han Population von Li, Huaixing, Wu, Ying, Loos, Ruth J F, Hu, Frank B, Liu, Yong, Wang, Jing, Yu, Zhijie, Lin, Xu

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