Editor Profile: Daniel Longley von Longley, Daniel B.

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The role of Ubiquitination in Apoptosis and Necroptosis von Roberts, Jamie Z., Crawford, Nyree, Longley, Daniel B.

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Cancer drug resistance: an evolving paradigm von Holohan, Caitriona, Van Schaeybroeck, Sandra, Longley, Daniel B., Johnston, Patrick G.

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The Multiple Roles of the IAP Super-family in cancer von Kumar, Swati, Fairmichael, Ciaran, Longley, Daniel B., Turkington, Richard C.

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FLIP(L): the pseudo‐caspase von Smyth, Peter, Sessler, Tamas, Scott, Christopher J., Longley, Daniel B.

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Patients with mesenchymal tumours and high Fusobacteriales prevalence have worse prognosis in colorectal cancer (CRC) von Salvucci, Manuela, Crawford, Nyree, Stott, Katie, Bullman, Susan, Longley, Daniel B, Prehn, Jochen H M

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FLIP as a therapeutic target in cancer von Humphreys, Luke, Espona‐Fiedler, Margarita, Longley, Daniel B.

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Fusobacterium nucleatum in the Colorectum and Its Association with Cancer Risk and Survival: A Systematic Review and Meta-analysis von Gethings-Behncke, Christian, Coleman, Helen G, Jordao, Haydee W T, Longley, Daniel B, Crawford, Nyree, Murray, Liam J, Kunzmann, Andrew T

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TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells von Woznicki, Jerzy A., Saini, Nisha, Flood, Peter, Rajaram, Subhasree, Lee, Ciaran M., Stamou, Panagiota, Skowyra, Agnieszka, Bustamante-Garrido, Milan, Regazzoni, Karine, Crawford, Nyree, McDade, Simon S., Longley, Daniel B., Aza-Blanc, Pedro, Shanahan, Fergus, Zulquernain, Syed A., McCarthy, Jane, Melgar, Silvia, McRae, Bradford L., Nally, Ken

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5-Fluorouracil: mechanisms of action and clinical strategies von Longley, Daniel B., Harkin, D. Paul, Johnston, Patrick G.

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The E3 ubiquitin ligase Itch regulates death receptor and cholesterol trafficking to affect TRAIL-mediated apoptosis von Holloway, James, Seeley, Aidan, Cobbe, Neville, Turkington, Richard C., Longley, Daniel B., Evergren, Emma

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Heterogeneous responses to low level death receptor activation are explained by random molecular assembly of the Caspase-8 activation platform von Matveeva, Anna, Fichtner, Michael, McAllister, Katherine, McCann, Christopher, Sturrock, Marc, Longley, Daniel B, Prehn, Jochen H M

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Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil von Chatterjee, Susanta, Naeli, Parisa, Onar, Okan, Simms, Nicole, Garzia, Aitor, Hackett, Angela, Coyle, Kelsey, Harris Snell, Patric, McGirr, Tom, Sawant, Tanvi Nitin, Dang, Kexin, Stoichkova, Zornitsa Vasileva, Azam, Yumna, Saunders, Mark P, Braun, Michael, Alain, Tommy, Tuschl, Thomas, McDade, Simon S, Longley, Daniel B, Gkogkas, Christos G, Adrain, Colin, Knight, John R P, Jafarnejad, Seyed Mehdi

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cFLIPL acts as a suppressor of TRAIL- and Fas-initiated inflammation by inhibiting assembly of caspase-8/FADD/RIPK1 NF-κB-activating complexes von Davidovich, Pavel, Higgins, Catherine A., Najda, Zaneta, Longley, Daniel B., Martin, Seamus J.

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ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer von Van Schaeybroeck, Sandra, Kalimutho, Murugan, Dunne, Philip D., Carson, Robbie, Allen, Wendy, Jithesh, Puthen V., Redmond, Keara L., Sasazuki, Takehiko, Shirasawa, Senji, Blayney, Jaine, Michieli, Paolo, Fenning, Cathy, Lenz, Heinz-Josef, Lawler, Mark, Longley, Daniel B., Johnston, Patrick G.

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Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification von Dunne, Philip D., Alderdice, Matthew, O'Reilly, Paul G., Roddy, Aideen C., McCorry, Amy M. B., Richman, Susan, Maughan, Tim, McDade, Simon S., Johnston, Patrick G., Longley, Daniel B., Kay, Elaine, McArt, Darragh G., Lawler, Mark

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surviveR: a flexible shiny application for patient survival analysis von Sessler, Tamas, Quinn, Gerard P., Wappett, Mark, Rogan, Emily, Sharkey, David, Ahmaderaghi, Baharak, Lawler, Mark, Longley, Daniel B., McDade, Simon S.

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TRAIL signaling promotes entosis in colorectal cancer von Bozkurt, Emir, Düssmann, Heiko, Salvucci, Manuela, Cavanagh, Brenton L, Van Schaeybroeck, Sandra, Longley, Daniel B, Martin, Seamus J, Prehn, Jochen H M

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classifieR a flexible interactive cloud-application for functional annotation of cancer transcriptomes von Quinn, Gerard P, Sessler, Tamas, Ahmaderaghi, Baharak, Lambe, Shauna, VanSteenhouse, Harper, Lawler, Mark, Wappett, Mark, Seligmann, Bruce, Longley, Daniel B, McDade, Simon S

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Identification of unique rectal cancer-specific subtypes von Kisakol, Batuhan, Matveeva, Anna, Salvucci, Manuela, Kel, Alexander, McDonough, Elizabeth, Ginty, Fiona, Longley, Daniel B., Prehn, Jochen H. M.

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