The discovery of BMS-275183: an orally efficacious novel taxane von Mastalerz, Harold, Cook, Donald, Fairchild, Craig R, Hansel, Steven, Johnson, Walter, Kadow, John F, Long, Byron H, Rose, William C, Tarrant, James, Wu, Mu-Jen, Xue, May Quifen, Zhang, Guifen, Zoeckler, Mary, Vyas, Dolatrai M

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Synthesis and Antitumor Activity of Novel C-7 Paclitaxel Ethers:  Discovery of BMS-184476 von Altstadt, Thomas J, Fairchild, Craig R, Golik, Jerzy, Johnston, Kathy A, Kadow, John F, Lee, Francis Y, Long, Byron H, Rose, William C, Vyas, Dolatrai M, Wong, Henry, Wu, Mu-Jen, Wittman, Mark D

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Eleutherobin, a New Cytotoxin that Mimics Paclitaxel (Taxol) by Stabilizing Microtubules von Lindel, Thomas, Jensen, Paul R, Fenical, William, Long, Byron H, Casazza, Anna Maria, Carboni, Joan, Fairchild, Craig R

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Eleutherobin, a novel cytotoxic agent that induces tubulin polymerization, is similar to paclitaxel (Taxol®) von LONG, B. H, CARBONI, J. M, WASSERMAN, A. J, CORNELL, L. A, CASAZZA, A. M, JENSEN, P. R, LINDEL, T, FENICAL, W, FAIRCHILD, C. R

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A Novel Application of a Pd(0)-Catalyzed Nucleophilic Substitution Reaction to the Regio- and Stereoselective Synthesis of Lactam Analogues of the Epothilone Natural Products von Borzilleri, Robert M, Zheng, Xiaoping, Schmidt, Robert J, Johnson, James A, Kim, Soong-Hoon, DiMarco, John D, Fairchild, Craig R, Gougoutas, Jack Z, Lee, Francis Y. F, Long, Byron H, Vite, Gregory D

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Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase von LONG, B. H, FAIRCHILD, C. R

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Synthesis and Biological Activity of Novel Epothilone Aziridines von Regueiro-Ren, Alicia, Borzilleri, Robert M, Zheng, Xiaoping, Kim, Soong-Hoon, Johnson, James A, Fairchild, Craig R, Lee, Francis Y. F, Long, Byron H, Vite, Gregory D

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Preclinical Pharmacology of BMS-275183, an Orally Active Taxane von ROSE, William C, LONG, Byron H, FAIRCHILD, Craig R, LEE, Francis Y. F, KADOW, John F

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Discovery of a Fluoroindolo[2,3-a]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11 von Saulnier, Mark G, Balasubramanian, Balu N, Long, Byron H, Frennesson, David B, Ruediger, Edward, Zimmermann, Kurt, Eummer, Jeffrey T, St. Laurent, Denis R, Stoffan, Karen M, Naidu, B. Narasimhulu, Mahler, Mikael, Beaulieu, Francis, Bachand, Carol, Lee, Frank Y, Fairchild, Craig R, Stadnick, Linda K, Rose, William C, Solomon, Carola, Wong, Henry, Martel, Alain, Wright, John J, Kramer, Robert, Langley, David R, Vyas, Dolatrai M

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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- d-glucopyran... von Balasubramanian, Balu N, St. Laurent, Denis R, Saulnier, Mark G, Long, Byron H, Bachand, Carol, Beaulieu, Francis, Clarke, Wendy, Deshpande, Milind, Eummer, Jeffrey, Fairchild, Craig R, Frennesson, David B, Kramer, Robert, Lee, Frank Y, Mahler, Mikael, Martel, Alain, Naidu, B. Narasimhulu, Rose, William C, Russell, John, Ruediger, Edward, Solomon, Carola, Stoffan, Karen M, Wong, Henry, Zimmermann, Kurt, Vyas, Dolatrai M

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SAR and pH Stability of Cyano-Substituted Epothilones von Regueiro-Ren, Alicia, Leavitt, Kenneth, Kim, Soong-Hoon, Höfle, Gerhard, Kiffe, Michael, Gougoutas, Jack Z, DiMarco, John D, Lee, Francis Y. F, Fairchild, Craig R, Long, Byron H, Vite, Gregory D

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Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP16-213 and VM26: a quantitative structure-activity relationship von Long, Byron H, Musial, Steven T, Brattain, Michael G

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Non-camptothecin topoisomerase I active compounds as potential anticancer agents von Long, Byron H, Balasubramanian, Balu N

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Synthesis and Biological Evaluation of 2-Acyl Analogues of Paclitaxel (Taxol) von Kingston, David G. I, Chaudhary, Ashok G, Chordia, Mahendra D, Gharpure, Milind, Gunatilaka, A. A. Leslie, Higgs, Paul I, Rimoldi, John M, Samala, Lakshman, Jagtap, Prakash G, Giannakakou, Paraskevi, Jiang, Yuan Q, Lin, Chii M, Hamel, Ernest, Long, Byron H, Fairchild, Craig R, Johnston, Kathy A

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BMS-247550 : A novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy von LEE, Francis Y. F, BORZILLERI, Robert, FAIRCHILD, Craig R, KIM, Soong-Hoon, LONG, Byron H, REVENTOS-SUAREZ, Carmen, VITE, Gregory D, ROSE, William C, KRAMER, Robert A

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Synthesis and biological activity of macrocyclic taxane analogues von Tarrant, James G., Cook, Donald, Fairchild, Craig, Kadow, John F., Long, Byron H., Rose, William C., Vyas, Dolatrai

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Synthesis and Biological Evaluation of 1-Deoxypaclitaxel Analogues von Kingston, David G. I, Chordia, Mahendra D, Jagtap, Prakash G, Liang, Jingyu, Shen, Ya-Ching, Long, Byron H, Fairchild, Craig R, Johnston, Kathy A

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Synthesis and bioactivity of 2,4-diacyl analogues of paclitaxel von Chordia, Mahendra D, Yuan, Haiqing, Jagtap, Prakash G, Kadow, John F, Long, Byron H, Fairchild, Craig R, Johnston, Kathy A, Kingston, David G.I

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Synthesis and antitumor activity of novel paclitaxel–chlorambucil hybrids von Wittman, Mark D., Kadow, John F., Vyas, Dolatrai M., Lee, Francis L., Rose, William C., Long, Byron H., Fairchild, Craig, Johnston, Kathy

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Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β-d-glucopyrano... von Balasubramanian, Balu N, St. Laurent, Denis R, Saulnier, Mark G, Long, Byron H, Bachand, Carol, Beaulieu, Francis, Clarke, Wendy, Deshpande, Milind, Eummer, Jeffrey, Fairchild, Craig R, Frennesson, David B, Kramer, Robert, Lee, Frank Y, Mahler, Mikael, Martel, Alain, Naidu, B. Narasimhulu, Rose, William C, Russell, John, Ruediger, Edward, Solomon, Carola, Stoffan, Karen M, Wong, Henry, Wright, John J, Zimmermann, Kurt, Vyas, Dolatrai M

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