Potentiation of Synaptic GluN2B NMDAR Currents by Fyn Kinase Is Gated through BDNF-Mediated Disinhibition in Spinal Pain Processing von Hildebrand, Michael E., Xu, Jian, Dedek, Annemarie, Li, Yi, Sengar, Ameet S., Beggs, Simon, Lombroso, Paul J., Salter, Michael W.

Volltext

Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing von Dedek, Annemarie, Xu, Jian, Kandegedara, Chaya M, Lorenzo, Louis-Étienne, Godin, Antoine G, De Koninck, Yves, Lombroso, Paul J, Tsai, Eve C, Hildebrand, Michael E

Volltext

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease von Xu, Jian, Chatterjee, Manavi, Baguley, Tyler D, Brouillette, Jonathan, Kurup, Pradeep, Ghosh, Debolina, Kanyo, Jean, Zhang, Yang, Seyb, Kathleen, Ononenyi, Chimezie, Foscue, Ethan, Anderson, George M, Gresack, Jodi, Cuny, Gregory D, Glicksman, Marcie A, Greengard, Paul, Lam, TuKiet T, Tautz, Lutz, Nairn, Angus C, Ellman, Jonathan A, Lombroso, Paul J

Volltext

Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders von Goebel-Goody, Susan M, Baum, Matthew, Paspalas, Constantinos D, Fernandez, Stephanie M, Carty, Niki C, Kurup, Pradeep, Lombroso, Paul J

Volltext

Disruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disorders von Karasawa, Takatoshi, Lombroso, Paul J.

Volltext

Extrasynaptic NMDA Receptors Couple Preferentially to Excitotoxicity via Calpain-Mediated Cleavage of STEP von Xu, Jian, Kurup, Pradeep, Zhang, Yongfang, Goebel-Goody, Susan M, Wu, Peter H, Hawasli, Ammar H, Baum, Matthew L, Bibb, James A, Lombroso, Paul J

Volltext

Regulation of a Protein Phosphatase Cascade Allows Convergent Dopamine and Glutamate Signals to Activate ERK in the Striatum von Valjent, Emmanuel, Pascoli, Vincent, Svenningsson, Per, Paul, Surojit, Enslen, Hervé, Corvol, Jean-Christophe, Stipanovich, Alexandre, Caboche, Jocelyne, Lombroso, Paul J., Nairn, Angus C., Greengard, Paul, Hervé, Denis, Girault, Jean-Antoine

Volltext

Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer’s disease mouse model von Zhang, Yongfang, Kurup, Pradeep, Xu, Jian, Carty, Nikisha, Fernandez, Stephanie M., Nygaard, Haakon B., Pittenger, Christopher, Greengard, Paul, Strittmatter, Stephen M., Nairn, Angus C., Lombroso, Paul J.

Volltext

Inhibition of striatal-enriched protein tyrosine phosphatase (STEP) activity reverses behavioral deficits in a rodent model of autism von Chatterjee, Manavi, Singh, Priya, Xu, Jian, Lombroso, Paul J., Kurup, Pradeep K.

Volltext

Tourette Syndrome and Tic Disorders: A Decade of Progress von SWAIN, JAMES E., M.D., Ph.D., F.R.C.P.C, SCAHILL, LAWRENCE, M.S.N., Ph.D, LOMBROSO, PAUL J., M.D, KING, ROBERT A., M.D, LECKMAN, JAMES F., M.D

Volltext

STEP₆₁ is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease von Kurup, Pradeep K, Xu, Jian, Videira, Rita Alexandra, Ononenyi, Chimezie, Baltazar, Graça, Lombroso, Paul J, Nairn, Angus C

Volltext

The Tyrosine Phosphatase STEP Mediates AMPA Receptor Endocytosis after Metabotropic Glutamate Receptor Stimulation von Zhang, Yang, Venkitaramani, Deepa V, Gladding, Clare M, Zhang, Yongfang, Kurup, Pradeep, Molnar, Elek, Collingridge, Graham L, Lombroso, Paul J

Volltext

Streptococcal Upper Respiratory Tract Infections and Exacerbations of Tic and Obsessive-Compulsive Symptoms: A Prospective Longitudinal Study von Leckman, James F., M.D, King, Robert A., M.D, Gilbert, Donald L., M.D, Coffey, Barbara J., M.D., M.S, Singer, Harvey S., M.D, Dure, Leon S., M.D, Grantz, Heidi, M.S.W, Katsovich, Liliya, M.B.A, Lin, Haiqun, M.D., Ph.D, Lombroso, Paul J., M.D, Kawikova, Ivana, M.D., Ph.D, Johnson, Dwight R., B.S, Kurlan, Roger M., M.D, Kaplan, Edward L., M.D

Volltext

NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling von Lombroso, Paul J, Paul, Surojit, Nairn, Angus C, Wang, Ping

Volltext

Striatal-enriched protein tyrosine phosphatase controls responses to aversive stimuli: implication for ethanol drinking von Legastelois, Rémi, Darcq, Emmanuel, Wegner, Scott A, Lombroso, Paul J, Ron, Dorit

Volltext

Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP) von Lambert, Lester J, Grotegut, Stefan, Celeridad, Maria, Gosalia, Palak, Backer, Laurent Js De, Bobkov, Andrey A, Salaniwal, Sumeet, Chung, Thomas Dy, Zeng, Fu-Yue, Pass, Ian, Lombroso, Paul J, Cosford, Nicholas Dp, Tautz, Lutz

Volltext

Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia von Deb, Ishani, Manhas, Namratta, Poddar, Ranjana, Rajagopal, Sathyanarayanan, Allan, Andrea M, Lombroso, Paul J, Rosenberg, Gary A, Candelario-Jalil, Eduardo, Paul, Surojit

Volltext

Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function von Lombroso, Paul J., Nairn, Angus C., Benedict, Jessie, Kamceva, Marija

Volltext

Tourette syndrome and obsessive–compulsive disorder von Lombroso, Paul J, Scahill, Lawrence

Volltext

Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades von Chen, Jun, Rusnak, Milan, Lombroso, Paul J., Sidhu, Anita

Volltext