Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease von Tufi, Roberta, Gandhi, Sonia, de Castro, Inês P., Lehmann, Susann, Angelova, Plamena R., Dinsdale, David, Deas, Emma, Plun-Favreau, Hélène, Nicotera, Pierluigi, Abramov, Andrey Y., Willis, Anne E., Mallucci, Giovanna R., Loh, Samantha H. Y., Martins, L. Miguel

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PINK1 cleavage at position A103 by the mitochondrial protease PARL von DEAS, Emma, PLUN-FAVREAU, Helene, ABRAMOV, Andrey Y, WOOD, Nicholas W, GANDHI, Sonia, DESMOND, Howard, KJAER, Svend, LOH, Samantha H. Y, RENTON, Alan E. M, HARVEY, Robert J, WHITWORTH, Alexander J, MARTINS, L. Miguel

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Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease von Yu, Yizhou, Fedele, Giorgio, Celardo, Ivana, Loh, Samantha H. Y., Martins, L. Miguel

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Evidence for involvement of the alcohol consumption WDPCP gene in lipid metabolism, and liver cirrhosis von O’Farrell, Felix, Aleyakpo, Benjamin, Mustafa, Rima, Jiang, Xiyun, Pinto, Rui Climaco, Elliott, Paul, Tzoulaki, Ioanna, Dehghan, Abbas, Loh, Samantha H. Y., Barclay, Jeff W., Martins, L. Miguel, Pazoki, Raha

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Enhancing NAD + salvage metabolism is neuroprotective in a PINK1 model of Parkinson's disease von Lehmann, Susann, Loh, Samantha H Y, Martins, L Miguel

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Blocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson’s disease von Popovic, Rebeka, Mukherjee, Amrita, Leal, Nuno Santos, Morris, Lydia, Yu, Yizhou, Loh, Samantha H. Y., Miguel Martins, L.

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Enhancing mitochondrial one-carbon metabolism is neuroprotective in Alzheimer’s disease models von Yu, Yizhou, Chen, Civia Z., Celardo, Ivana, Tan, Bryan Wei Zhi, Hurcomb, James D., Leal, Nuno Santos, Popovic, Rebeka, Loh, Samantha H. Y., Martins, L. Miguel

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Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective von Wilson, Emma L., Yu, Yizhou, Leal, Nuno S., Woodward, James A., Patikas, Nikolaos, Morris, Jordan L., Field, Sarah F., Plumbly, William, Paupe, Vincent, Chowdhury, Suvagata R., Antrobus, Robin, Lindop, Georgina E., Adia, Yusuf M., Loh, Samantha H. Y., Prudent, Julien, Martins, L. Miguel, Metzakopian, Emmanouil

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The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors von Hardy, Rachel E, Chung, Injae, Yu, Yizhou, Loh, Samantha H Y, Morone, Nobuhiro, Soleilhavoup, Clement, Travaglio, Marco, Serreli, Riccardo, Panman, Lia, Cain, Kelvin, Hirst, Judy, Martins, Luis M, MacFarlane, Marion, Pryde, Kenneth R

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Correction: Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease von Yu, Yizhou, Fedele, Giorgio, Celardo, Ivana, Loh, Samantha H. Y., Martins, L. Miguel

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Forcing contacts between mitochondria and the endoplasmic reticulum extends lifespan in a Drosophila model of Alzheimer's disease von Garrido-Maraver, Juan, Loh, Samantha H. Y., Martins, L. Miguel

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Upregulation of Tribbles decreases body weight and increases sleep duration von Popovic, Rebeka, Yu, Yizhou, Leal, Nuno Santos, Fedele, Giorgio, Loh, Samantha H Y, Martins, L Miguel

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Combined Transcriptomic and Proteomic Analysis of Perk Toxicity Pathways von Popovic, Rebeka, Celardo, Ivana, Yu, Yizhou, Costa, Ana C., Loh, Samantha H. Y., Martins, L. Miguel

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MAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins von Lam, David, Dickens, David, Reid, Elizabeth B, Loh, Samantha H.Y, Moisoi, Nicoleta, Martins, L. Miguel

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Enhancing folic acid metabolism suppresses defects associated with loss of Drosophila mitofusin von Garrido-Maraver, Juan, Celardo, Ivana, Costa, Ana C., Lehmann, Susann, Loh, Samantha H. Y., Martins, L. Miguel

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dATF4 regulation of mitochondrial folate-mediated one-carbon metabolism is neuroprotective von Celardo, Ivana, Lehmann, Susann, Costa, Ana C, Loh, Samantha HY, Miguel Martins, L

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Suppression of intestinal dysfunction in a Drosophila model of Parkinson's disease is neuroprotective von Fedele, Giorgio, Loh, Samantha H Y, Celardo, Ivana, Leal, Nuno Santos, Lehmann, Susann, Costa, Ana C, Martins, L Miguel

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Mitochondrial ROS signalling requires uninterrupted electron flow and is lost during ageing in flies von Graham, Charlotte, Stefanatos, Rhoda, Yek, Angeline E. H., Spriggs, Ruth V., Loh, Samantha H. Y., Uribe, Alejandro Huerta, Zhang, Tong, Martins, L. Miguel, Maddocks, Oliver D. K., Scialo, Filippo, Sanz, Alberto

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Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS von Hall, Claire E., Yao, Zhi, Choi, Minee, Tyzack, Giulia E., Serio, Andrea, Luisier, Raphaelle, Harley, Jasmine, Preza, Elisavet, Arber, Charlie, Crisp, Sarah J., Watson, P. Marc D., Kullmann, Dimitri M., Abramov, Andrey Y., Wray, Selina, Burley, Russell, Loh, Samantha H.Y., Martins, L. Miguel, Stevens, Molly M., Luscombe, Nicholas M., Sibley, Christopher R., Lakatos, Andras, Ule, Jernej, Gandhi, Sonia, Patani, Rickie

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Mitochondrial complex I derived ROS regulate stress adaptation in Drosophila melanogaster von Scialò, Filippo, Sriram, Ashwin, Stefanatos, Rhoda, Spriggs, Ruth V., Loh, Samantha H.Y., Martins, L. Miguel, Sanz, Alberto

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