Increased brain penetration and potency of a therapeutic antibody using a monovalent molecular shuttle von Niewoehner, Jens, Bohrmann, Bernd, Collin, Ludovic, Urich, Eduard, Sade, Hadassah, Maier, Peter, Rueger, Petra, Stracke, Jan Olaf, Lau, Wilma, Tissot, Alain C, Loetscher, Hansruedi, Ghosh, Anirvan, Freskgård, Per-Ola

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Region-specific permeability of the blood–brain barrier upon pericyte loss von Villaseñor, Roberto, Kuennecke, Basil, Ozmen, Laurence, Ammann, Michelle, Kugler, Christof, Grüninger, Fiona, Loetscher, Hansruedi, Freskgård, Per-Ola, Collin, Ludovic

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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier von Villaseñor, Roberto, Ozmen, Laurence, Messaddeq, Nadia, Grüninger, Fiona, Loetscher, Hansruedi, Keller, Annika, Betsholtz, Christer, Freskgård, Per-Ola, Collin, Ludovic

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Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer’s Disease von Borroni, Edilio, Bohrmann, Bernd, Grueninger, Fiona, Prinssen, Eric, Nave, Stephane, Loetscher, Hansruedi, Chinta, Shankar J, Rajagopalan, Subramanian, Rane, Anand, Siddiqui, Almas, Ellenbroek, Bart, Messer, Juerg, Pähler, Axel, Andersen, Julie K, Wyler, Rene, Cesura, Andrea M

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Separation of Fast from Slow Anabolism by Site-specific PEGylation of Insulin-like Growth Factor I (IGF-I) von Metzger, Friedrich, Sajid, Waseem, Saenger, Stefanie, Staudenmaier, Christian, van der Poel, Chris, Sobottka, Bettina, Schuler, Angelika, Sawitzky, Mandy, Poirier, Raphael, Tuerck, Dietrich, Schick, Eginhard, Schaubmar, Andreas, Hesse, Friederike, Amrein, Kurt, Loetscher, Hansruedi, Lynch, Gordon S., Hoeflich, Andreas, De Meyts, Pierre, Schoenfeld, Hans-Joachim

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Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport von Ruderisch, Nadine, Schlatter, Daniel, Kuglstatter, Andreas, Guba, Wolfgang, Huber, Sylwia, Cusulin, Carlo, Benz, Jörg, Rufer, Arne Christian, Hoernschemeyer, Joerg, Schweitzer, Christophe, Bülau, Tina, Gärtner, Achim, Hoffmann, Eike, Niewoehner, Jens, Patsch, Christoph, Baumann, Karlheinz, Loetscher, Hansruedi, Kitas, Eric, Freskgård, Per-Ola

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Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span von von Kienlin, Markus, Künnecke, Basil, Metzger, Friedrich, Steiner, Guido, Richards, J. Grayson, Ozmen, Laurence, Jacobsen, Helmut, Loetscher, Hansruedi

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In vitro pharmacological selectivity profile of oseltamivir prodrug (Tamiflu ®) and active metabolite von Lindemann, Lothar, Jacobsen, Helmut, Schuhbauer, Diana, Knoflach, Frederic, Gatti, Silvia, Wettstein, Joseph G., Loetscher, Hansruedi, Chu, Tom, Ebeling, Martin, Paulson, James C., Prinssen, Eric, Brockhaus, Manfred

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Presenilins Are Processed by Caspase-type Proteases von Loetscher, Hansruedi, Deuschle, Ulrich, Brockhaus, Manfred, Reinhardt, Dieter, Nelboeck, Peter, Mous, Jan, Grünberg, Jürgen, Haass, Christian, Jacobsen, Helmut

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Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia? von Loetscher, Hansruedi, Niederhauser, Olivier, Kemp, John, Gill, Rammy

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Amyloidogenic Function of the Alzheimer's Disease-Associated Presenilin 1 in the Absence of Endoproteolysis von Steiner, Harald, Romig, Helmut, Pesold, Brigitte, Philipp, Uwe, Baader, Miriam, Citron, Martin, Loetscher, Hansruedi, Jacobsen, Helmut, Haass, Christian

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Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor von Loetscher, Hansruedi, Pan, Yu-Ching E., Lahm, Hans-Werner, Gentz, Reiner, Brockhaus, Manfred, Tabuchi, Hisahiro, Lesslauer, Werner

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Cargo Delivery into the Brain by in vivo identified Transport Peptides von Urich, Eduard, Schmucki, Roland, Ruderisch, Nadine, Kitas, Eric, Certa, Ulrich, Jacobsen, Helmut, Schweitzer, Christophe, Bergadano, Alessandra, Ebeling, Martin, Loetscher, Hansruedi, Freskgård, Per-Ola

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Disturbed Cross Talk between Insulin-Like Growth Factor I and AMP-Activated Protein Kinase as a Possible Cause of Vascular Dysfunction in the Amyloid Precursor Protein/Presenilin 2... von Lopez-Lopez, Cristina, Dietrich, Marcelo O, Metzger, Friedrich, Loetscher, Hansruedi, Torres-Aleman, Ignacio

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Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier von Villaseñor, Roberto, Ozmen, Laurence, Messaddeq, Nadia, Grüninger, Fiona, Loetscher, Hansruedi, Keller, Annika, Betsholtz, Christer, Freskgård, Per-Ola, Collin, Ludovic

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TUMOR-NECROSIS-FACTOR RECEPTORS - STRUCTURE AND FUNCTION von ROTHE, J, GEHR, G, LOETSCHER, H, LESSLAUER, W

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PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and Inflammation von Richards, J. Grayson, Higgins, Guy A, Ouagazzal, Abdel-Mouttalib, Ozmen, Laurence, Kew, James N. C, Bohrmann, Bernd, Malherbe, Pari, Brockhaus, Manfred, Loetscher, Hansruedi, Czech, Christian, Huber, Gerda, Bluethmann, Horst, Jacobsen, Helmut, Kemp, John A

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Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences von Dembic, Zlatko, Loetscher, Hansruedi, Gubler, Ueli, Pan, Yu-Ching E., Lahm, Hans-Werner, Gentz, Reiner, Brockhaus, Manfred, Lesslauer, Werner

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Crystal structure of the novel aspartic proteinase zymogen proplasmepsin II from Plasmodium falciparum von James, Michael N.G, Bernstein, Nina Khazanovich, Cherney, Maia M, Loetscher, Hansruedi, Ridley, Robert G

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Role of Caspase-3 Activation in Cerebral Ischemia-Induced Neurodegeneration in Adult and Neonatal Brain von Gill, Ramanjit, Soriano, Marc, Blomgren, Klas, Hagberg, Henrik, Wybrecht, Remy, Miss, Marie-Therese, Hoefer, Sandra, Adam, Geo, Niederhauser, Olivier, Kemp, John A., Loetscher, Hansruedi

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