Enhancing the accuracy of next-generation sequencing for detecting rare and subclonal mutations von Salk, Jesse J., Schmitt, Michael W., Loeb, Lawrence A.

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Human Cancers Express a Mutator Phenotype: Hypothesis, Origin, and Consequences von Loeb, Lawrence A

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Detection of ultra-rare mutations by next-generation sequencing von Schmitt, Michael W, Kennedy, Scott R, Salk, Jesse J, Fox, Edward J, Hiatt, Joseph B, Loeb, Lawrence A

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Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage von Kennedy, Scott R, Salk, Jesse J, Schmitt, Michael W, Loeb, Lawrence A

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DNA polymerase delta in dna replication and genome maintenance von Prindle, Marc J., Loeb, Lawrence A.

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Multiple Mutations and Cancer von Loeb, Lawrence A., Loeb, Keith R., Anderson, Jon P.

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Human Cancers Express a Mutator Phenotype von Bielas, Jason H., Loeb, Keith R., Rubin, Brian P., True, Lawrence D., Loeb, Lawrence A.

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The Werner syndrome protein is distinguished from the Bloom syndrome protein by its capacity to tightly bind diverse DNA structures von Kamath-Loeb, Ashwini, Loeb, Lawrence A, Fry, Michael

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Human cancers express mutator phenotypes: origin, consequences and targeting von Loeb, Lawrence A

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Mutational heterogeneity in human cancers: origin and consequences von Salk, Jesse J, Fox, Edward J, Loeb, Lawrence A

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DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice von Loeb, Lawrence A, Vermulst, Marc, Wanagat, Jonathan, Kujoth, Gregory C, Bielas, Jason H, Rabinovitch, Peter S, Prolla, Tomas A

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Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging von DAI, Dao-Fu, SANTANA, Luis F, RABINOVITCH, Peter S, VERMULST, Marc, TOMAZELA, Daniela M, EMOND, Mary J, MACCOSS, Michael J, GOLLAHON, Katherine, MARTIN, George M, LOEB, Lawrence A, LADIGES, Warren C

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Extensive subclonal mutational diversity in human colorectal cancer and its significance von Loeb, Lawrence A., Kohrn, Brendan F., Loubet-Senear, Kaitlyn J., Dunn, Yasmin J., Ahn, Eun Hyun, O’Sullivan, Jacintha N., Salk, Jesse J., Bronner, Mary P., Beckman, Robert A.

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Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan von Salk, Jesse J., Loubet-Senear, Kaitlyn, Maritschnegg, Elisabeth, Valentine, Charles C., Williams, Lindsey N., Higgins, Jacob E., Horvat, Reinhard, Vanderstichele, Adriaan, Nachmanson, Daniela, Baker, Kathryn T., Emond, Mary J., Loter, Emily, Tretiakova, Maria, Soussi, Thierry, Loeb, Lawrence A., Zeillinger, Robert, Speiser, Paul, Risques, Rosa Ana

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Cancers exhibit a mutator phenotype: clinical implications von Loeb, Lawrence A, Bielas, Jason H, Beckman, Robert A

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Lethal Mutagenesis: Targeting the Mutator Phenotype in Cancer von Fox, Edward J, Loeb, Lawrence A

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Implications of genetic heterogeneity in cancer von Schmitt, Michael W., Prindle, Marc J., Loeb, Lawrence A.

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The Mitochondrial Theory of Aging and Its Relationship to Reactive Oxygen Species Damage and Somatic mtDNA Mutations von Loeb, Lawrence A., Wallace, Douglas C., Martin, George M.

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Detection of Ultra-Rare Mitochondrial Mutations in Breast Stem Cells by Duplex Sequencing von Ahn, Eun Hyun, Hirohata, Kensen, Kohrn, Brendan F, Fox, Edward J, Chang, Chia-Cheng, Loeb, Lawrence A

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Protein Tolerance to Random Amino Acid Change von Guo, Haiwei H., Choe, Juno, Loeb, Lawrence A., Hood, Leroy E.

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