Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release von Jin, Hong, Kelley, Ann C, Loakes, David, Ramakrishnan, V

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Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution von Holliger, Philipp, Ghadessy, Farid J, Ramsay, Nicola, Boudsocq, François, Loakes, David, Brown, Anthony, Iwai, Shigenori, Vaisman, Alexandra, Woodgate, Roger

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Molecular breeding of polymerases for amplification of ancient DNA von Pääbo, Svante, Woodgate, Roger, Holliger, Philipp, Cadet, Jean, Vaisman, Alexandra, Gasparutto, Didier, d'Abbadie, Marc, Hofreiter, Michael, Loakes, David

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Directed Evolution of DNA Polymerase, RNA Polymerase and Reverse Transcriptase Activity in a Single Polypeptide von Ong, Jennifer L., Loakes, David, Jaroslawski, Szymon, Too, Kathleen, Holliger, Philipp

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Polymerase engineering: towards the encoded synthesis of unnatural biopolymers von Loakes, David, Holliger, Philipp

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Lethal Mutagenesis of Picornaviruses with N-6-Modified Purine Nucleoside Analogues von GRACI, Jason D, TOO, Kathleen, BROWN, Daniel M, CAMERON, Craig E, SMIDANSKY, Eric D, EDATHIL, Jocelyn P, BARR, Eric W, HARKI, Daniel A, GALARRAGA, Jessica E, BOLLINGER, J. Martin, PETERSON, Blake R, LOAKES, David

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Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome von Kelley, Ann C, Voorhees, Rebecca M, Weixlbaumer, Albert, Ramakrishnan, V, Loakes, David

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Lethal Mutagenesis of Poliovirus Mediated by a Mutagenic Pyrimidine Analogue von GRACI, Jason D, HARKI, Daniel A, LOAKES, David, CAMERON, Craig E, KORNEEVA, Victoria S, EDATHIL, Jocelyn P, TOO, Kathleen, FRANCO, David, SMIDANSKY, Eric D, PAUL, Aniko V, PETERSON, Blake R, BROWN, Daniel M

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Synthetic polymers and their potential as genetic materials von Pinheiro, Vitor B., Loakes, David, Holliger, Philipp

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Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose) von Eustermann, Sebastian, Neuhaus, David, Yang, Ji-Chun, Ahel, Ivan, West, Stephen C, Brockmann, Christoph, Mehrotra, Pawan Vinod, Loakes, David

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Synthetic polymers and their potential as genetic materials von Pinheiro, Vitor B, Loakes, David, Holliger, Philipp

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Evolving a Polymerase for Hydrophobic Base Analogues von Loakes, David, Gallego, José, Pinheiro, Vitor B, Kool, Eric T, Holliger, Philipp

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Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53 von Wong, Tuck Seng, Rajagopalan, Sridharan, Townsley, Fiona M, Freund, Stefan M, Petrovich, Miriana, Loakes, David, Fersht, Alan R

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3-Nitropyrrole and 5-nitroindole as universal bases in primers for DNA sequencing and PCR von Loakes, David, Brown, Daniel M., Linde, Solvita, Hill, Fergal

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Isolation of Antirhinoviral Sesquiterpenes from Ginger (Zingiber officinale) von Denyer, Clive V, Jackson, Peter, Loakes, David M, Ellis, Malcolm R, Young, David A. B

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Solution structure and dynamics of DNA duplexes containing the universal base analogues 5-nitroindole and 5-nitroindole 3-carboxamide von Gallego, José, Loakes, David

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Synthesis and Some Biochemical Properties of a Novel 5,6,7,8-Tetrahydropyrimido[4,5-c]pyridazine Nucleoside von Loakes, David, Brown, Daniel M., Salisbury, Stephen A., McDougall, Mark G., Neagu, Constantin, Nampalli, Satyam, Kumar, Shiv

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Darwinian chemistry: towards the synthesis of a simple cell von Loakes, David, Holliger, Philipp

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Template properties of mutagenic cytosine analogues in reverse transcription von Suzuki, Tetsuya, Moriyama, Kei, Otsuka, Chie, Loakes, David, Negishi, Kazuo

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Nucleotides and nucleic acids; oligo- and polynucleotides

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